Care Oncology Clinic- Repurposed drugs for cancer

In this episode of the podcast I discuss the potential applications of ChatGPT in healthcare with Dr Harvey Castro.

Dr Castro is a physician, healthcare consultant and author, on a mission to increase awareness of digital health and implement new changes in healthcare. He has just released a new book, titled 'ChatGPT and Healthcare: The Key To The New Future of Medicine'. He is passionate about helping others to succeed in the healthcare and digital health industries and so I was grateful to have him on the podcast.

What is ChatGPT and how might it transform healthcare?

ChatGPT is a powerful language generation model that has the ability to understand and respond to natural language input. In the field of healthcare, ChatGPT has the potential to revolutionize the way patients interact with their medical providers and access information about their health.

If you would like to learn more about Dr Castro and his work please see the links below:

'ChatGPT and Healthcare: The Key To The New Future of Medicine' https://www.amazon.co.uk/ChatGPT-Healthcare-Key-Future-Medicine-ebook/dp/B0BS1YYNL9

 LinkedIn profile
 linkedin.com/in/harveycastromd
Websites
• harveycastromd.info (Company)
• successreinvention.com (Blog)
• doximity.com/cv/harveycastromd (Other)
https://wikitia.com/wiki/Dr._Harvey_Castro
Twitter
@HarveycastroMD
Facebook
https://www.facebook.com/HarveyCastroMD
Instagram
https://www.instagram.com/harveycastromd/
Youtube
https://www.youtube.com/harveycastromd

In this episode I raise awareness of the cancer metabolism study that I will be working on alongside Isabella Cooper at the University of Westminster. 

This is a self-funded study that requires support from a number of sources. Establishing key partnerships and engaging with an audience who are equally as passionate about this subject is vital to our success. 


To find out more about the study and to see how you can contribute, see the following link:

https://beatbraincancer.co.uk


For more information, you can find our most recent interview about the study here:

https://www.youtube.com/watch?v=EK6KGd7K_J0&t=1065s

Mary Biles is a medical cannabis writer and educator. She has written extensively on the subject, authoring a book titled ‘The CBD Book: The Essential Guide to CBD oil, and hosts the podcast series Cannabis Voices.

In this episode we will be covering the subject of cannabis and cannabis based medicines.

Mary Biles can be found at:
https://www.marybiles.com

Cannabis Voices

Show notes:

Cancard-

A medical ID card, recognised by the police, indicating to any third-party that you are consuming cannabis for medical reasons.

https://cancard.co.uk

ProjectCBD-

A California based not for profit with an established history covering the subject with fact checked, evidence based information on a variety of conditions

https://www.projectcbd.org

Project Twenty21-

The largest observational medical cannabis study in the UK, gathering data on the efficacy of cannabis-based medicines for a wide range of conditions.

https://www.drugscience.org.uk/twenty21/

Sapphire Clinics

The first UK medical cannabis clinic registered by the Care Quality Commision.

https://www.sapphireclinics.com/about/

This episode represents the final part of a series of conversations regarding the safety of gadolinium based contrast agents.

Here we discuss who is most at risk for retaining gadolinium and how we can effectively get it out of the body using chelation therapy.

I am joined by:

Dr Richard Semelka -

Dr Richard Semelka is a leading expert in Radiology for body MRI and gadolinium toxicity.

He has written over 370 peer-reviewed papers and 16 text-books. and is the first doctor to publish on the entity of gadolinium deposition disease.

Dr semelka offers clinical medical consultations for individuals experiencing gadolinium toxicity and in this discussion we will be observing practically how this is treated in the clinic.


Kate Skardon -

A patient advocate, continuing chelation therapy to remove gadolinium from the body following devastating consequences. Her story can be found here:   

https://www.youtube.com/watch?v=4aozx...

https://www.youtube.com/watch?v=1RvHA...


Debbie Lambert-

A patient advocate who seeks to raise awareness about Gadolinium Deposition Disease through various mediums, including the links below:

https://m.facebook.com/pg/livingwithg...

https://twitter.com/lambertdebb


Show notes:

HOPO Therapeutics- oral chelation
http://www.hopotx.com/science/

SAGE- Symptoms Associated with Gadolinium Exposure
https://pubs.rsna.org/doi/abs/10.1148/radiol.2021211349

Dr. Wagner is a clinical nephrologist. He is the Director of the Kidney Institute of New Mexico as well as being the acting Associate Chief of Research and Renal Section Chief for the VA in Albuquerque.

This is the second time Dr. Wagner has been on the podcast with his research team. In this episode we re-examine the mechanisms behind gadolinium retention and receive updates on new discoveries.

To fund Dr. Wagner’s work you can donate to the Kidney Institute of New Mexico at

https://www.unmfund.org/fund/unm-kidney-institute-of-new-mexico/

Links:

Reveal Pharmaceuticals, Gadolinium-free MRI contrast agents products.

http://www.revealpharma.com


The FDA adverse event reporting system

https://open.fda.gov/data/faers/


Gadolinium-Based Contrast Agent Use, Their Safety, and Practice Evolution

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8378745/

Dr. Elena Gross is a neuroscientist with a PhD in clinical research (specifically Ketosis in migraine prevention). She is also the CEO & founder of KetoSwiss.

KetoSwiss develops and markets high quality exogenous ketone body therapeutics for use in disease prevention and treatment of specifically neurological diseases.

KetoSwiss-  https://www.keto.swiss

You can find Dr. Elena Gross on:

Twitter - https://twitter.com/drelenagross
Instagram - https://www.instagram.com/drelenagross/
Youtube - https://www.youtube.com/c/DrElenaGross

Gemma Herbertson is the creator of the Neuro Fronteirs website http://neurofrontiers.org and the Diets for Epilepsy Facebook group.

In this episode we talk about the upcoming Neuro Frontier Summit, holistic approaches to managing epilepsy and her son Eddy's recovery following a brain tumour diagnosis as a baby. Eddy greatly benefited from neuroplastic therapies, a personalised diet and hyperbaric oxygen therapy under the guidance of experienced practitioners. Gemma seeks to raise awareness of these approaches through the website, related events and discussion groups.

Show notes:

Education: The Neuro Frontier Summit - https://www.neurofrontiers.org/summit/

ANI Diet  https://www.neurofrontiers.org/anti-n...

Exchange Breathing Method  https://www.neurofrontiers.org/natura...

Epilepsy  https://www.neurofrontiers.org/condit...

Neuroplasticity Therapies  https://www.neurofrontiers.org/neurop...

Practitioner Locator  https://www.neurofrontiers.org/natura...

In this episode we discuss how the Care Oncology Clinic supports cancer patients with integrating repurposed drugs into their treatment regime. 

The clinic aims to complement standard treatments with repurposed drugs under the guidance of expert clinicians in order to deliver a safe, evidence based approach. Data is collected in order to improve outcomes for patients with various forms of cancer.

We discuss the drug selection process, how safety and efficacy is monitored, what are the findings so far and future directions of the clinic.

Resources mentioned in discussion:

The Frontiers paper from 2019 which takes in research methods and strategy, and discusses some of the challenges associated with generating good quality real world evidence. It also present preliminary outcomes data in our cohort of 95 GBM patients:

https://www.frontiersin.org/articles/10.3389/fphar.2019.00681/full

The best place for patients to find white papers aggregating a sample of relevant research literature on the COC Protocol meds in the context of different types of disease is on the US sister company website under the tab “COC – Select Cancer Types”. For example, here is the link to one on Ovarian cancer: https://careoncology.com/the-coc-protocol-in-ovarian-cancer/

In this episode I chat to Dr. Stuart Farrimond. 

Dr Farrimond is a science and medical writer, presenter and educator. He is also a trained medical doctor and qualified teacher. 

Dr Farrimond has written a number of international best selling books including ‘The Science of Cooking, Science of Spice, and most recently ‘The Science of Life’, in which he answers 219 key questions on how to live your best life. He has made numerous TV and radio appearances as well as having produced several articles in various publications.

In this episode of the podcast we discuss his experiences as a brain cancer survivor with a medical background and what influence this has had on his life.

8-year-old Deliah Sitorius had been fighting a rare brain cancer for almost a year with chemotherapy . Unfortunately this was unsuccessful and she stopped treatment immediately. Deliah was given hope after her mother discovered the tumour has a rare mutation often seen in lung cancer. Since applying a more targeted, personalised approach using a drug called Lorlatinib the tumour has been shrinking.

Loratinib is a third generation ALK ROS1 tyosine kinase inhibitor, specifically designed to overcome known ALK resistance mutations. It is able to penetrate the blood brain barrier and more recently we have seen paediatric brain cancer patients who are responding very well to the drug.