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    Dr. Craig Heller: Using Temperature To Optimize Performance, Brain & Body Health

    enOctober 04, 2021
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    Podcast Summary

    • The Key to Mental and Physical Performance: Controlling Your Core Body TemperatureLearn how your body maintains homeostasis through thermal regulation and cool down effectively through specialized vascular compartments on your palms, soles, and upper face. Skip the ice bath and opt for a cold shower for better physiological and performance benefits.

      Learning to control your core body temperature can greatly increase both mental and physical performance, regardless of the environment that you're in. Dr. Craig Heller explains how thermal regulation works in the body to maintain homeostasis for healthy neurons and organ function. Contrary to popular belief, putting a cold pack on your head or neck is not the optimal way to cool down quickly and can actually lead to hyperthermia. Instead, specialized vascular compartments on the palms, soles, and upper face are the primary avenues for heat loss. While whole body immersion in cold water like an ice bath may provide a shock of adrenaline, it does not necessarily translate into any physiological or performance benefits compared to a cold shower.

    • Benefits of Taking a Cold Shower or Bath before ExerciseA quick cold shower or bath before working out regulates the body temperature, sustains performance, and can increase speed or distance, but should be used appropriately to achieve optimal results.

      Taking a cold shower or bath before aerobic activity helps increase the body's capacity to absorb excess heat. This helps sustain the performance and increase speed or distance of the workout. It only takes a few minutes to extract the heat from the body and the core temperature goes down, preventing heat loss. For anaerobic athletes like strength trainers, the temperature increase is local, and the body's core temperature does not rise as fast. Taking a cold shower or bath is beneficial for regulating body temperature and improving athletic performance, but its benefits depend on how one uses it. It could increase speed or distance, but some athletes use it to go faster, not necessarily further.

    • The Impact of Muscle Temperature on FatigueHigh muscle temperature can lead to fatigue and muscle failure, and traditional cooling methods may not be effective in preventing hyperthermia. Even non-targeted muscles can be influenced by the rise in temperature.

      Muscles produce heat during anaerobic activity and can reach hyperthermic limits, which can lead to muscle fatigue. The rise in temperature of the muscle is the most immediate factor that causes muscle fatigue. When the muscle temperature gets above 39 or 39 and five, it can shut off the enzyme required for fuel delivery and supply to the mitochondria, leading to muscular failure. Although muscles have fail-safe mechanisms to ensure hyperthermia doesn't occur, cooling off quadriceps by throwing a nice, cool towel on them isn't an effective strategy. Also, the biceps may not be the direct focal point, but they will still experience a fatigue curve influenced by the rise in temperature generated by lower body exercises.

    • The Science of Cooling the BodyWhile remedies like ice water or a neck towel may provide temporary relief from overheating, they do not fully cool the body. The thermoregulatory system of the body is complex and requires regulating temperature through the entire body surface.

      The skin, fascia, and muscles under the surface of our body act as insulators and prevent heat from escaping. Drinking ice water or using an ice pack on the back of the neck can provide temporary relief from overheating, but they do not have the full capacity to cool our body. Our thermoregulatory system works like a thermostat, and the pre optic interior hypothalamus in our brain serves as the thermostat, which requires input from our overall body surface to regulate temperature. Cooling the torso with an ice vest constricts heat loss portals and impairs heat loss rate. Putting a cold towel on the neck can protect the brain, but it could trick us into thinking that we have cooled off, whereas the brain could cook due to excessive hot blood flow from the body.

    • The Role of Temperature on Cognitive Capacity and Body FunctioningRising temperature can decrease cognitive capacity and lead to dangerous hyperthermic temperature. The body has portals that can be leveraged for performance, but it's important to recognize and prevent heat stroke during physical activity.

      Rising temperature decreases cognitive capacity and can lead to dangerous hyperthermic temperature. The brain receives thermal afferent information from the whole body and integrates the representation of body temperature. There are portals located in the hairless skin that can be leveraged for performance. These portals are in the pads of feet, upper part of the face for primates, portions of the ears for rabbits, inner surfaces for bears, and the tongue. When individuals transition into heat stroke, they feel exhausted, miserable and experience high heart rate. Heat stroke can occur during practice due to motivation to push.

    • The Science of Heat Loss in Mammals and Human PerformanceMale mammals use limited surface areas without fur to lose heat. Proper cooling of skin surfaces can improve human performance during exercise. Wearing thin protectors on hands and feet can maximize heat loss.

      Male mammals have evolved special blood vessels in limited surface areas without fur to lose heat, which are shunts between the arteries and veins. These shunts enable the blood to bypass tiny capillaries and flow directly from arteries to veins. In the skin, these vessels are located below the epidermis and are absent in the backs of the hands. Gloves and thick socks impede heat loss and hinder performance during exercise. To maximize heat loss, it is recommended to wear thin protectors on hands and feet. Proper cooling of glamour skin surfaces can improve human performance during exercise. Cooling upper half of the face improves endurance and pouring water on the head can increase cognitive performance.

    • The Brain-Cooling Mechanism above the Beard Line and Its BenefitsCooling the brain through the non-hairy skin above the beard line can decrease inflammation and blood flow, benefiting athletes during anaerobic exercises and potentially offsetting physical damage. However, the mechanism still requires more investigation.

      Cooling the brain through the non-hairy skin above the beard line is one of the natural mechanisms for decreasing inflammation and blood flow. Athletes can benefit from cooling during anaerobic exercises like dips, increasing their capacity to do more reps by decreasing swelling. The blood vessels that cool the brain can also be used to offset physical damage, but it is still a controversial topic. Through the skull, the blood flows in a strange way, and these blood vessels are primarily thought to be ways that blood is leaving the brain. These discoveries need more investigation.

    • The Benefits of Hand Cooling for Athletes' WorkoutsCooling the palms for three minutes can enhance workout performance and reduce muscle soreness, allowing for more workouts. Cooling technology can be a game-changer for athletes looking to improve their workout performance and reduce recovery times.

      Cooling the palms of the hands for three minutes can significantly improve an athlete's workout performance. It can reduce the occurrence of delayed onset muscle soreness, allowing for more workouts between recovery periods. This was demonstrated through an athlete who doubled his work volume and tripled what he could do after standardizing intervals for resting and cooling. Cooling technology can enhance performance in various activities, including push-ups, bench presses, and endurance work. The technology is not yet portable, but was utilized by special ops soldiers who experienced its benefits. Overall, cooling technology can be a game-changer for athletes seeking to improve their workout performance and reduce recovery times.

    • CoolMitt technology improves endurance and mobility in various situationsTyroBio's CoolMitt technology enhances performance and is in beta testing with professional sports teams and the military. The wearable device fits under personal protective gear, making it useful for workers in high-temperature environments. Sign up for alerts on the company's website.

      Cooling technology developed by TyroBio, called CoolMitt, has been shown to improve endurance and mobility in a variety of situations, including multiple sclerosis patients playing golf, athletes in hot environments, and military special operators. The technology is currently in beta testing with professional sports teams and the military, but the company plans to eventually make it available to the general public. Although there have been many positive studies of the technology over the years, there hasn't been a clear pathway for getting it out to consumers. The development of wearable devices, which can fit under personal protective gear, has been particularly useful for military and medical workers facing high temperatures. While the technology is not currently available for purchase, interested individuals can sign up on the company's website to be alerted when the product becomes available.

    • CoolBot Technology: Enhancing Performance by Cooling the Body through the HandsThe CoolBot is a technology that cools the body temperature through the hands, enhancing performance. Even individuals can use a crude version with a frozen packet or juice can, taking care not to seal up heat loss or using water that is too cold.

      Cooling the body through the hands can enhance performance, and the CoolBot is a technology developed at Stanford University that cools the hand and, thus, the body temperature. Standardized on three minutes, the technology offers maximum benefit in the first two to three minutes. While the CoolBot is being used by sports teams and the military, an individual can use a crude version of the protocol with a packet of frozen peas or juice can, taking care not to seal up heat loss by long usage or using water that is too cold. Optimal results for an individual can be determined by testing. If the hand is cool to touch after switching peas, it indicates a successful heat loss.

    • Effective Cooling Methods for OverheatingTo cool down efficiently, use cooling methods like cold packs on the face, palms, and soles of the feet as they have larger surface areas for radiating heat. Cooling the radiating surfaces is more efficient than standard treatments.

      To cool down efficiently when overheated, it's better to put cooling methods like cold packs on the face, palms, and soles of the feet rather than on armpits, groin, or neck. This is because the efficiency of heat transfer between two objects increases with convection of the medium, and the areas mentioned have larger surface areas for radiating heat. Standard treatments recommended by medical organizations for hyperthermia are not as efficient as cooling the radiating surfaces. Also, putting cold packs with no convective stream of the cooling medium, like frozen peas, is not optimal as boundary layers decrease efficacy. Heat transfer involves convection, radiation, and convection.

    • Use of Heated Limbs to Warm up Hypothermic IndividualsWhen dealing with hypothermia, heat up extremities and torso using heated limbs. This method pulls blood into the limb, effectively warming it and the whole body in a science-backed solution for quick and effective warming. Also, warm liquids should be provided, but not too hot.

      When dealing with hypothermic individuals, it is important to heat up their extremities as well as their torso to prevent further heat loss. The use of one heated appendage, such as an arm, can effectively warm up the whole body by pulling more blood into the limb and effectively heating it. This method has been successful in preventing shivering and normalizing core temperature in a short amount of time. This is a science-backed solution that could be used in hospitals, military settings, athletes, and civilians doing other types of work to quickly and effectively warm up hypothermic individuals. It is also important to note that warm liquids could be given to someone who is hypothermic, but not too hot.

    • Palmer Cooling and Warming Up for DogsPalmer cooling uses a dog's instinctual behavior to cool them down by targeting the AVS found in their paws and palms. Warming up is also important for flexibility, not just raising body temperature. Core body temperature can be measured through a salvage seal or tympanic temperature.

      Palmer cooling, a technique used to cool down overheated dogs, was made possible due to the discovery of special blood vessels called arterial venous anastomosis (AVS). AVS is a connection between arteries and veins found only in the hands and feet. This technique works because dogs instinctively know to stand in bodies of water to cool themselves off and have the advantage that their paws and palms are essentially the same things. Warming up before exercise is essential to avoid joint damage and increase flexibility. Interestingly, the major contribution of warming up is not to raise the temperature but to increase flexibility. The best way to measure core body temperature is a salvage seal, but tympanic (ear) temperature is also reliable.

    • Improving Sports Performance through Cooling Workouts and Proper GearDecreasing heat loss and proper ventilation in helmets and gloves, along with cooling workouts, can enhance performance without the negative effects of anabolic steroids. It's crucial to prioritize safe and natural methods for improving athletic performance.

      Improving performance can be done by decreasing heat loss and ensuring proper ventilation in helmets and gloves during sports activities. Cooling workouts can also lead to a true conditioning effect as it increases the number of contractual elements in muscles and causes them to get bigger, resulting in a performance-enhancing effect. This can occur even without the cooling workout. Anabolic steroids, which are commonly used to improve recovery time and ability to synthesize protein, have negative effects and are banned in many sports organizations. It is important to note that while there is no research comparing Palmer cooling to anabolic steroids, there is plenty of research available on the latter.

    • Steroid Use in Bodybuilding and Sports PerformanceSteroids only show a marginal increase in bench press performance, while paying attention to nutrition, sleep, and other factors such as temperature has a more significant impact. Military special operators and black bears are interesting groups to study for their ability to perform under unpredictable conditions.

      Steroids are not an effective tool for bodybuilding and sports performance, with independent studies showing only a 1% per week increase in bench press performance with or without steroids. Alternative parameters like temperature may have a more significant impact on performance while paying attention to nutrition and sleep is essential. Military special operators are an interesting group because they are trained to perform under unpredictable and variable conditions. Shivering increases metabolism but exercise can take metabolism up to 10 times, and it can happen without being exposed to cold. Black bears do hibernate, and researchers can implant them with EEG, EKG, and temperature sensors to study their hibernation patterns.

    • Brown Fat and Hibernation: How Animals Stay WarmBrown fat helps animals produce heat during hibernation, and humans also have brown fat that can be stimulated by ice packs, but caution should be exercised to avoid shivering and activation of brown fat.

      Bears maintain their body temperature while hibernating by shivering if the temperature drops below 33-34 degrees Celsius, while smaller animals like ground squirrels can drop their body temperature to one or two degrees Celsius above the environment. Brown fat is a tissue that helps animals produce heat during hibernation by storing energy and having lots of mitochondria and blood supply. Humans also have brown fat, which is distributed along with other fat tissue, and can be stimulated by ice packs; however, putting ice packs on the upper back may not be the best way to stimulate brown fat activation as it can affect the vertebral arteries and cause shivering and activation of brown fat.

    • Brown fat, brain freeze, and fidgeting: How temperature affects the body's functions.The amount of brown fat in one's body varies, while cold temperatures activate the sympathetic nervous system causing brain freeze. Fidgeting burns significant calories, and preliminary data suggests heat devices alleviate migraines.

      The activation of brown fat is a sympathetic nervous system response, and any lowering of core temperature will let the thermostat say you're too cold and turn on sympathetic. Different people have different amounts of brown fat, and newborns have more brown fat than adults. The brain freeze from eating something cold like an ice cream cone or drinking a cold beverage is caused by vasomotor change, which is an increase in blood pressure. There is preliminary data that suggests using a heat device can help reduce migraines, but it's anecdotal and doesn't have a decent dataset. Fidgeters burn off a large amount of calories (800-2500 calories per day) by way of shaking their knee or moving around a lot.

    • The Connection Between Muscle Activity and Energy ConsumptionSmall movements like tapping your foot can produce a lot of heat. Energy drinks may hinder muscular performance and affect the adenosine system. Keeping the temperature cool while sleeping can improve muscle oxygenation. Muscle hypoxia releases adenosine, increasing blood flow to muscles.

      Muscle activity increases energy consumption and heat production, and even small movements like tapping your foot can result in four times the amount of energy being lost as heat. While energy drinks and pre-workout drinks may contain thermogenic compounds to increase body temperature, they may also hinder muscular performance by inhibiting the adenosine system that supports the oxygenation of muscle. The effects of these drinks may vary depending on their cocktail of compounds and glucose sources. Additionally, keeping the room cool and dark while sleeping is advised, and there may be other useful tips for better sleep that people don't hear much about. Muscle hypoxia releases adenosine, which causes blood vessels to dilate, increasing blood flow to the muscles.

    • Tips for Better Sleep Hygiene with Cognitive Behavioral TherapyEstablish a consistent sleep schedule, avoid screens before bedtime, relax before sleeping, regulate temperature with a cooler environment and try sleeping with a limb out to help regulate body temperature. Wearing socks for toe-sensitive spots can enhance thermal comfort.

      Cognitive behavioral therapy is more emphasized than pharmacology in the sleep medicine community to increase sleep hygiene. Rules such as having regular bedtime and wake time, avoiding screens before bedtime, doing relaxing activities, and keeping the sleep environment cooler for thermoregulation are recommended. Sleeping with one leg or hand out in cool environments can help regulate body temperature passively. Temperature-sensitive spots in the body are the toes, making wearing socks helpful for thermal comfort in cooler environments. However, socks may not be necessary if it is too warm. Finally, a rational and science-grounded explanation is given for why it's better to sleep in a cool room.

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    In this episode, my guest is Dr. Layne Norton, Ph.D., one of the world’s top experts in nutrition and training for physical fitness. We discuss how to evaluate scientific evidence and the validity of different practices aimed at achieving fat loss, muscle strength and hypertrophy, microbiome health, vitality, and longevity. We explore many hotly debated topics, including fasting, seed oils, saturated fats, sugar, red meat, artificial/low-calorie sweeteners, and GLP-1 agonists (e.g., Ozempic). Additionally, we delve into the timing of protein and carbohydrate intake relative to fasting and exercise, fat loss and sleep, and the benefits of dietary protein and fiber on overall health. We also discuss how to accelerate hypertrophy and fat loss, improve strength, whether we need to train to “failure,” how to enhance exercise recovery, and how to manage pain. We cover training before versus after age 50, whether metabolism changes with age, and the connection between muscle health and longevity. We also address why certain behaviors and supplements might work for some people but not others. Listeners to this episode will benefit greatly from Layne’s science-based expertise on a wide range of topics, including health, nutrition, and fitness. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Mateina: https://drinkmateina.com/huberman Eight Sleep: https://www.eightsleep.com/huberman Maui Nui: https://mauinuivenison.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Dr. Layne Norton 00:01:49 Sponsors: Mateina, Eight Sleep, Maui Nui 00:06:39 Science-Based Evidence, Mechanism vs. Outcome 00:14:31 Meta-analysis, Methods, Evidence Quality 00:22:45 Evidence Hierarchy, Randomized Controlled Trials, Cohort Data 00:33:53 Sponsor: AG1 00:35:05 “Don’t Turn Your Brain Off”; Protein Synthesis 00:42:01 Protein Synthesis, Refractory Response; Resistance Training   00:46:05 Protein Intake, Intermittent Fasting & Training 00:54:52 Tool: Total Protein Intake, Distribution & Protein Synthesis 01:00:25 Muscle Quality, Protein Remodeling, Muscle Growth 01:05:34 Sponsor: LMNT 01:06:46 Early vs. Late Time-Restricted Eating; Fasting Blood Glucose & HbA1c 01:10:30 Carbohydrate Timing, Individual Response, Placebo; Tool: Tracking Diet 01:19:50 “The Norton Method”; Tool: Consistency 01:25:16 Resistance & Cardiovascular Training; Competition; Immune System & Rest 01:33:50 Mind & Body Effects, Stress; Belief Effects 01:41:30 Training to Failure, Reps in Reserve, Hypertrophy & Strength Training 01:50:24 Fatigue & Training to Failure, Speed, Strength Training 01:59:06 Tool: Training After 50, Consistency 02:09:12 Fat Cells, Diabetes, Exercise 02:16:50 Metabolism & Age-Related Changes?, Appetite 02:23:17 Ozempic, Mounjaro, GLP-1 Agonists, Lean Mass, “Food Noise” 02:33:42 GLP-1 Agonists, Judgement & Obesity 02:40:19 Sugar, Excess Calories, Body Weight 02:49:16 Satiety, Sugar & Calorie Budget 02:54:56 Tool: Individualization, Context & Diet Psychology 02:57:22 Seed Oils, Butter, Olive Oil 03:06:56 Red Meat, Carcinogenic?; Simple Diet; Fiber Benefits 03:13:43 Saturated Fat, Cholesterol; Seed Oils 03:18:41 Artificial & Low-Calorie Sweeteners, Insulin, Appetite 03:29:06 Artificial & Low-Calorie Sweeteners, Gut Microbiome; Cancer 03:37:58 Tools: Training Recovery, Glycogen Replenishment; Stress & Activity 03:45:56 Collagen Supplementation, Skin & Nails, Whey Protein 03:57:00 Evidence-Based Approach 04:01:41 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures
    Huberman Lab
    enAugust 12, 2024

    Dr. Martha Beck: Access Your Best Self With Mind-Body Practices, Belief Testing & Imagination

    Dr. Martha Beck: Access Your Best Self With Mind-Body Practices, Belief Testing & Imagination
    In this episode, my guest is Dr. Martha Beck, Ph.D., a Harvard-trained sociologist, bestselling author, and one of the world’s foremost experts on personal exploration and development.  Dr. Beck shares specific frameworks and practices to tap into your unique and deepest desires, core truths, and best life direction—all elements that comprise your authentic self. She also explains how to align your work and relationships of all kinds with your true self and how to embrace the discomfort and process of leaving unhealthy relationships. We discuss how to deal with negative thoughts and emotions, grapple with societal norms, and improve body awareness to gauge your inner truth. We also discuss codependency and self-abandonment - and how to exit and recover from these experiences.  By the end of the episode, you will have learned numerous practical tools to access your best self and live a richly fulfilling life.  Access the full show notes for this episode at hubermanlab.com. Dr. Beck's Wayfinder Life Coach Training: https://marthabeck.com/life-coach-training Thank you to our sponsors AG1: https://drinkag1.com/huberman BetterHelp: https://betterhelp.com/huberman Helix Sleep: https://helixsleep.com/huberman LMNT: https://drinklmnt.com/huberman Waking Up: https://wakingup.com/huberman Timestamps 00:00:00 Dr. Martha Beck 00:01:34 Sponsors: BetterHelp, Helix Sleep & LMNT 00:05:34 Tool: Perfect Day Exercise 00:15:31 “Clear Eyed”, Male vs. Female 00:23:31 Family & Work; Directed Attention & Miracles 00:30:21 Sponsor: AG1 00:32:10 Unease, Restlessness & Guilt; Life Worth, Fear 00:37:22 Accessing the Subconscious; Compassionate Witness Self 00:46:16 Finding Self, Suffering, Anxiety; Tool: “KIST”, Self-Parenting 00:54:01 Self, Radiance, Death; Awakening 00:59:14 Suffering & Compassionate Attention 01:02:10 Challenging Internal Thoughts, Understanding Truth, Body & Mind; 01:08:44 Sponsor: Waking Up 01:10:20 Western Society & Pressure 01:18:30 Tool: Sensing Truth in Body; Meditation, “Stopping the World” 01:25:02 Energy, Magnetoreception, Pet’s Death 01:33:49 Lying to Ourselves, Addiction 01:38:18 Tool: “Integrity Cleanse”, Lies; The Light 01:47:32 Relationship with Loss; Love, Self-Abandonment & Codependency 01:55:10 Romantic Relationships; Jobs & Family 02:02:06 Hurting Others, Relationship Imbalance 02:06:55 Tool: True Empathy 02:11:26 “Happiness is an Inside Job”, Codependency 02:18:58 Live Your Joy, Western Society 02:24:41 Relationships, Love & Integrity, “Feeling Good By Looking Weird” 02:30:42 “I Like It!”, Punk Rock Music, Love 02:34:24 Honesty & Essential Self; Helping People & Healers 02:42:12 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures
    Huberman Lab
    enAugust 05, 2024

    AMA #18: Cold Therapy Advice, Skin Health Tips, Motivation, Learning Strategies & More

    AMA #18: Cold Therapy Advice, Skin Health Tips, Motivation, Learning Strategies & More
    Welcome to a special edition of the 18th Ask Me Anything (AMA) episode, part of Huberman Lab Premium. This episode is a recording of the live stream AMA, exclusive to our Premium members. We've decided to make the full-length version available to everyone, including non-members of Huberman Lab Premium. Huberman Lab Premium was launched for two main reasons. First, it was launched in order to raise support for the main Huberman Lab podcast — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation and other donors. If you're not yet a member but enjoyed this full-length livestream AMA, we invite you to join Huberman Lab Premium. By subscribing, you'll gain access to exclusive benefits including our regular monthly full-length AMA episodes, AMA transcripts, podcast episode transcripts, early access to live events and more. Additionally, a significant portion of your membership proceeds contributes to advancing human scientific research. You can learn more about the research we were able to support in our Annual Letter 2023. If you're a Huberman Lab Premium member, you can access the transcript for this AMA episode here. Timestamps 00:00 Introduction & Announcements 00:15 Supporting Mental & Physical Health Research 01:56 Exciting New Research Initiatives 03:39 Skin Health & Appearance 14:46 Cold Therapy Benefits & Guidelines 21:18 Self-Motivation Strategies 27:05 Understanding REM Sleep 28:45 Morning Routine: Exercise & Cold Exposure 29:17 The Importance of REM Sleep 29:49 Non-Sleep Deep Rest (NSDR) Protocols 31:27 REM Sleep Rebound & Compensation 32:55 Impactful School Strategies for Learning 34:19 Meditation & Micro Gaps in Learning 39:13 Physical Activity & Learning 41:01 Exploring Shilajit & Testosterone 47:51 Writing Process & Overcoming Obstacles 51:32 Addiction & Recovery Resources 53:47 Closing Remarks & Gratitude Disclaimer & Disclosures
    Huberman Lab
    enAugust 02, 2024

    Dr. Peter Attia: Supplements for Longevity & Their Efficacy

    Dr. Peter Attia: Supplements for Longevity & Their Efficacy
    In this episode, my guest is Dr. Peter Attia, M.D., a Stanford and Johns Hopkins School of Medicine-trained physician expert in improving human healthspan and lifespan. Dr. Attia is also the host of The Drive podcast and author of the best-selling book Outlive.  We discuss the NAD pathway in human cells and its possible links to aging and health. We evaluate how supplementation can augment molecules in the NAD pathway; we compare NAD, NMN, and NR, different routes of administration, their safety, and bioavailability. Then, we discuss the broader research and clinical literature on longevity to decide if supplementation with NAD, NR, NMN, rapamycin, or resveratrol can indeed extend lifespan.  Finally, we each describe our supplement regimens and compare the role of supplementation to behaviors such as sleep, nutrition, and exercise for longevity. We also discuss whether tests of biological age are true indicators of aging and whether normal radiation levels increase cancer risk.  Listeners of this episode will learn if supplements purported to improve lifespan show any efficacy and the behaviors and other factors that can prevent disease and extend lifespan. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/huberman Levels: https://levels.link/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps 00:00:00 Dr. Peter Attia, NAD Pathway 00:02:31 Sponsors: LMNT, Levels & Eight Sleep 00:06:38 Categories of Longevity Approaches 00:17:22 Peter’s Supplements; Rapamycin & Research Data 00:25:01 NAD Pathway: Energy & DNA Repair; Knock-Out & Knock-In, Klotho 00:30:35 Sponsor: AG1 00:32:25 Yeast, Sirtuins, Caloric Restriction & Lifespan 00:38:56 Sirtuins, Transgenic Mice, Gender & Lifespan 00:43:42 DNA Repair, Sirtuins, Cancer; Resveratrol 00:53:31 Perform with Dr. Andy Galpin Podcast 00:54:18 NAD & NADH, Reactive Oxygen Species (ROS), Mitochondrial Health 01:02:17 NAD vs NR vs NMN Supplementation; IV & Oral Routes 01:11:33 NR vs. NMN, Doses, Side Effects; Interventions Testing Program 01:17:43 Fatty Liver Disease & NR; NMN & Glucose; Clinical Significance 01:25:17 Safety & FDA, NMN & NR Supplementation; Skin Cancer Benefits 01:30:38 Longevity, NR & NMN Supplementation, Inflammation 01:41:00 Rapamycin & Immune Function 01:44:37 Biological Aging Tests, Chronologic & Biologic Age; Vigor  01:55:24 Radiation & Cancer Risk 01:58:12 Tool: Self-Care in 50s-70s & Aging; Energy Decline 02:07:12 Tool: Exercise Timing & Energy Levels 02:11:22 Peter’s Supplements 02:18:46 Andrew’s Supplements 02:24:34 Tool: Supplement Use vs. Critical Behaviors; Titanic Analogy  02:26:52 NAD Pathway Supplementation for Longevity? 02:28:52 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Social Media, Neural Network Newsletter Disclaimer
    Huberman Lab
    enJuly 29, 2024

    Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

    Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity
    In this episode, my guest is Dr. Stacy Sims, Ph.D., an exercise physiologist, nutrition scientist, and expert in female-specific nutrition and training for health, performance, and longevity. We discuss which exercise and nutrition protocols are ideal for women based on their age and particular goals. We discuss whether women should train fasted, when and what to eat pre- and post-training, and how the menstrual cycle impacts training and nutrition needs. We also explain how to use a combination of resistance, high-intensity, and sprint interval training to effectively improve body composition, hormones, and cardiometabolic health, offset cognitive decline, and promote longevity.  We also discuss supplements and caffeine, the unique sleep needs of women based on age, whether women should use deliberate cold exposure, and how saunas can improve symptoms of hot flashes and benefit athletic performance. Dr. Sims challenges common misconceptions about women’s health and fitness and explains why certain types of cardio, caloric restriction, and low-protein diets can be harmful to women’s metabolic health. Listeners will learn a wealth of actionable information on how to improve their training and nutrition to enhance their health and how to age with greater ability, mobility, and vitality. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Maui Nui Venison: https://mauinuivenison.com/huberman  Eight Sleep: https://eightsleep.com/huberman   Waking Up: https://wakingup.com/huberman  Timestamps 00:00:00 Dr. Stacy Sims 00:02:24 Sponsors: Maui Nui, Eight Sleep & Waking Up 00:07:03 Intermittent Fasting, Exercise & Women 00:12:50 Cortisol & Circadian Rhythm, Caffeine & Training 00:17:25 Reps in Reserve, Rate of Perceived Exertion (RPE); Age & Women 00:21:06 Pre-Training Meal & Brain, Kisspeptin 00:26:45 Post-Training Meal & Recovery Window 00:29:59 Sponsor: AG1 00:31:48 Hormones, Calories & Women 00:34:24 Women, Strength Improvements & Resistance Training 00:39:10 Tool: Women & Training Goals by Age Range 00:44:16 Women, Perimenopause, Training & Longevity 00:47:14 Women & Training for Longevity, Cardio, Zone 2 00:51:42 Tools: How to Start Resistance Training, Machines; Polarized Training 00:58:23 Perform with Dr. Andy Galpin Podcast 00:59:10 Menstrual Cycle & Training, Tool: Tracking & Individual Variability 01:04:31 Tool: 10-Minute Rule; High-Intensity Training & Menstrual Cycle 01:08:36 “Train Hard & Eat Well”; Appetite, Nutrition & Menstrual Cycle 01:12:22 Oral Contraception, Hormones, Athletic Performance; IUD 01:20:57 Evaluating Menstrual Blood, PCOS; Hormones & Female Athletes 01:26:31 Iron, Fatigue; Blood Testing & Menstrual Cycle 01:29:33 Caffeine & Perimenopause; Nicotine, Schisandra 01:34:24 Deliberate Cold Exposure & Women, Endometriosis; Tool: Sauna & Hot Flashes 01:42:19 Tools: “Sims’ Protocol”: Post-Training Sauna & Performance; “Track Stack” 01:49:37 Women, Hormones & Sleep, Perimenopause & Sleep Hygiene 01:52:54 Supplements: Creatine, Water Weight, Hair Loss; Vitamin D3 01:57:21 Protein Powder; Adaptogens & Timing 02:00:11 Pregnancy & Training; Cold & Hot Exposure 02:06:19 Tool: Women in 50s & Older, Training & Nutrition for Longevity 02:09:38 Tool: Women in 20s-40s & Training, Lactate 02:12:18 Tool: What is High-Intensity Training?, Cardiovascular Sets & Recovery 02:17:22 Training for Longevity, Cellular & Metabolic Changes 02:19:30 Nutrition, 80/20 Rule 02:23:30 Listening to Self 02:26:00 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter  Disclaimer & Disclosures
    Huberman Lab
    enJuly 22, 2024

    Dr. Stuart McGill: Build a Strong, Pain-Proof Back

    Dr. Stuart McGill: Build a Strong, Pain-Proof Back
    In this episode, my guest is Dr. Stuart McGill, Ph.D., a distinguished professor emeritus of spine biomechanics at the University of Waterloo and a world expert on spine anatomy and physiology, back pain, and rehabilitation. We discuss the most common sources of back pain, how back pain can be assessed (including self-assessment techniques), and how to design a personalized recovery plan to reduce back pain. We discuss how to train for lifelong fitness, reduce injury risk, and protect your back and joints based on your age and personal goals. We also discuss how to prevent back pain, build core stability, and explain how “McGill’s Big 3” exercises protect and strengthen the back. Dr. McGill, who is exceptionally fit in his late 60s, describes his low-time investment, personal training routine, and the specific exercises he uses for mobility, strength, and cardiovascular fitness. We also discuss controversial issues in the back pain and rehabilitation field, including how pain originates, the biopsychosocial model of pain, and treatments such as platelet-rich plasma (PRP). This episode provides clear, actionable tools to strengthen, prevent, and remedy back pain and injury so you can be pain-free while enjoying sports, exercise, and daily activities at any age. Access the full show notes for this episode at hubermanlab.com. Watch the clip on back pain relief and spine anatomy that accompanies this episode. Demonstration of The McGill Method Thank you to our sponsors AG1: https://drinkag1.com/huberman Helix Sleep: https://helixsleep.com/huberman BetterHelp: https://betterhelp.com/huberman Waking Up: https://wakingup.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Dr. Stuart McGill 00:02:33 Sponsors: Helix Sleep, BetterHelp & Waking Up 00:06:23 What Causes Back Pain?; Genetics, Dog Breed Analogy 00:12:55 Tool: Skeleton & Body Type; Spine Flexibility & Discs 00:20:25 Flexibility & Exercises; Discs & Collagen 00:25:43 Sponsor: AG1 00:27:32 Stress & Tipping Point; Athletic Tradeoffs, Triathletes 00:36:17 Back Pain, Goals & Training Program 00:45:57 Spine Hygiene, Back Pain, Powerlifting 00:53:33 Genetics & Running 00:59:34 Sponsor: LMNT 01:00:46 Rehabilitation & Reducing Volume; Injury 01:07:42 Tool: Training for Lifelong Fitness, Injury & Joints 01:17:40 Pain Types, Biopsychosocial Model of Pain 01:26:15 Coaching, Explosivity & Endurance 01:32:43 Virtual Surgery & Rest, Pain Recovery 01:41:25 Tool: McGill’s Big 3; Building Back Strength & Stability 01:46:39 Inversion Tables & Spine Deloading, Disc Bulge, Tool: Lumbar Support 01:51:09 Tool: Daily Walking; Sitting 01:55:33 Deadlift & Bone Density, Glute-Ham Raise 02:06:20 Training & Age, Osteoporosis, Tool: Deadlift Alternatives 02:16:47 Tools: Biblical Training Week; Spine Stability & McGill’s Big 3; Shrinking & Age 02:24:16 Platelet-Rich Plasma (PRP); Disc Damage 02:27:56 Tools: Biblical Training Week & Strength Exercises, Neck Strength 02:35:24 Tools: Sword Play, Distal Limb Loading, Training for Symmetry 02:42:38 Tools: Biblical Training Week, Mobility & Cardiovascular Exercises, Athletic Panel 02:49:22 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures
    Huberman Lab
    enJuly 15, 2024

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