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    E27: The Great Inflation Debate, Amazon gets spicy on Twitter, rethinking supply chains & more

    enMarch 27, 2021

    Podcast Summary

    • A friendly debate between Sacks and Chamath on All In PodcastThe audience preferred Sacks as a mentor for startup growth and podcast moderator, while Chamath was chosen as the preferred choice in a hypothetical bar fight. Sacks acknowledged the poll results might have been influenced by his larger following on social media.

      During a recent episode of the All In Podcast, the hosts David Freiberg, David Sacks, and Chamath Palihapitiya engaged in a friendly debate, with Sacks representing the interests of the wealthy and established, and Chamath advocating for the underdogs. The audience participated by casting votes in various polls, revealing that Sacks was preferred as a mentor for startup growth and a podcast moderator, while Chamath was chosen as the preferred choice in a hypothetical bar fight. Despite the friendly banter, Sacks acknowledged that the poll results might have been influenced by his larger following on social media. Additionally, the discussion touched on an AI breakthrough and a humorous moment regarding misperceptions of Chamath's physical appearance. Sacks' humility and good sportsmanship were on display as he acknowledged the results and poked fun at himself. Overall, the episode showcased the camaraderie and playful dynamic among the hosts, as well as their willingness to engage with their audience.

    • A lighthearted debate on inflation, leg circumference, and hypothetical bar fightsDespite differing views on inflation's impact, the hosts agreed on the importance of financial literacy and making informed decisions.

      During their discussion, the podcast hosts touched upon various topics including measuring leg circumference, physical fights, and inflation. Jason, who is known for his taekwondo skills, was jokingly challenged to a hypothetical bar fight. They also debated the impact of inflation on goods and services, with some believing it could lead to significant price increases while others saw it as beneficial. Chamath expressed his view that inflation creates equality, referencing the year 1979. David, however, took issue with Chamath's perspective and shared insights from a respected mentor. The lower income population was discussed, with most spending above their income, leading to consumption or investment. In summary, the hosts engaged in a lively conversation covering a range of topics, from personal anecdotes to economic theories.

    • Income distribution and consumption patterns impact inflationThe lowest income earners drive inflation through spending every dollar, while the middle class spends more due to credit access. The wealthy save and invest, contributing less to inflation. Pandemics and large money transfers can artificially increase consumption and commodity prices, leading to inflation, but it's not an exact analogy to the 1970s.

      Income distribution and consumption patterns play a significant role in driving inflation. The lowest income earners spend every dollar they earn, while the middle class spends a bit more due to access to credit. The richest 20% save and invest, contributing less to inflation through consumption. Inflation arises from the volume of economic activity, and as more people consume, inflation increases. The pandemic has led to the printing of trillions of dollars, artificially increasing consumption and driving up commodity prices, which in turn fuels inflation. Historically, similar programs leading to large transfers of money to a significant portion of the population have resulted in inflation peaking, as seen in the late 1970s. However, it's important to note that this is not an exact analogy, and other factors also contribute to inflation. The debate between Jamal and David centered around the validity of this take, with David expressing concerns about the accuracy of the comparison to the 1970s and the potential for inflation to escalate further.

    • Focusing solely on GINI index overlooks economic complexitiesConsider economic growth, real wage growth, poverty rates, and power concentrations for a balanced view on economic conditions

      Focusing solely on the GINI index as an indicator of economic success or failure is oversimplified. The year 1979, despite a low GINI index, was marked by a severe recession, high unemployment, inflation, and economic hardship for many. This period, known as the "stagflation misery index," led to decreased wealth concentration among the top 0.1%, but it also resulted in economic stagnation and hardship for the broader population. Economic booms, rather than equalities, tend to create and widen the wealth gap. Instead, it's crucial to consider economic growth, real wage growth, poverty rates, and concentrations of power when evaluating economic conditions. Additionally, the discussion highlighted the impact of policy decisions, such as the discontinuation of transfer payments during the Carter administration, and their long-term consequences on economic inequality.

    • Biden's Spending Spree and US-China Trade RelationsBiden's large spending plans may drive inflation, benefit those without investments, and potentially change US-China trade dynamics.

      The first 60 days of the Biden presidency have seen an unprecedented amount of spending, with $1.9 trillion already allocated and a proposed $3 trillion infrastructure package. This era of spend, spend, spend is expected to drive inflation, commodity prices, and potentially suppress wealth creation for the rich. However, it may also benefit those without investments by giving them the ability to make more in real income. The speakers agreed that the US-China trade agreement in 2001 was a mistake, as it led to the outsourcing of jobs and the devastation of wage growth for the average worker. They discussed the possibility of unwinding this situation and making the relationship between the US and China a two-way street. It was suggested that Bush may have granted China permanent normal trade relations in exchange for their support in the UN resolution to go to war with Iraq in 2003. Overall, the conversation touched on the economic consequences of US-China trade policies and the potential for future changes.

    • The relationship between US and China is complex and multifacetedThe notion of a clear-cut victory or defeat between US and China oversimplifies the complexities of globalization and the evolving role of governments in the 21st century. Inflation is not the only solution to close the wealth gap.

      The relationship between businesses and countries, particularly the United States and China, is complex and multifaceted. It's not as simple as labeling one government as innately better or worse than another. Many American companies operate globally, and the economy of China is deeply interconnected with that of the United States. The notion of a clear-cut victory or defeat between these two entities is a simplistic view that doesn't account for the intricacies of globalization and the evolving role of governments in the 21st century. Furthermore, the idea that inflation is the only way to close the wealth gap by making everyone poorer is not accurate. Instead, the economic landscape has been growing significantly over the past few decades, and finding a path forward requires a nuanced understanding of these complexities.

    • Misconceptions about income inequality and povertyDespite income inequality, economic growth and government transfers have led to fewer people living in poverty, contrary to popular belief.

      While some people may feel poorer due to the wealth gap, the idea that people are actually becoming poorer is not factually correct. The Gini index, which measures income inequality, does not fully account for government transfers and their impact on reducing poverty. During periods of strong economic growth, such as the Reagan-Clinton boom, real wage growth and the ability to fund social safety net programs increase. The economy's strength under Reagan and Clinton led to high approval ratings despite scandals. The decline in interest rates since the 1980s, caused by Paul Volcker breaking inflation, led to more investment and economic growth. The misconception that GDP is not increasing independently of these factors is not accurate.

    • Economic Growth Trends and Inflation ConcernsDespite fluctuations, the American economy has grown significantly since the 1950s. High inflation can impact financial assets and the wealthy, but deflationary trends suggest it may not be a major concern for most.

      While the economy experiences periods of growth and recession, the overall trend is one of growth, with the American economy growing from less than a trillion dollars in the 1950s to over $23 trillion today. The speaker questions the significance of small percentage differences in growth rates and suggests that the natural tendency is for the economy to continue growing, despite fluctuations. However, high inflation can be detrimental, particularly for financial assets and the top quartile of the population, but may not be as much of a concern due to deflationary trends in modern society. The speaker also argues that hyperinflation, which is characterized by rapidly increasing prices, is unlikely in today's economy due to deflationary trends and the limited role of the government in areas like NFTs, Bitcoin, and cryptocurrencies.

    • United front against adversariesAmericans should prioritize unity against adversaries like Russia and China over domestic debates, while companies like Amazon defend themselves and implement policies.

      Despite various concerns, economic growth and business success are not the primary issues at hand. Instead, there's a focus on addressing larger adversaries like Russia and China, who aim to build authoritarian countries and control the economy and planet. The debate among Americans over issues like minimum wage and healthcare should be put aside in favor of a united front against these adversaries. Additionally, companies like Amazon are standing up for themselves against political attacks and implementing policies like minimum wage increases.

    • Senators Criticize Tech CEOs Over Labor and RegulationSenators challenged tech CEOs on labor practices and regulation during heated discussions, with limited time leading to frustration and simplified responses.

      During a discussion, Senator Bernie Sanders criticized Amazon's Jeff Bezos for spending large sums to prevent workers from unionizing, while Bezos countered by questioning Sanders' record on minimum wage in his own state. Mark Zuckerberg, during a congressional hearing, proposed increasing regulations for social media sites, which some argue could create a competitive advantage for larger platforms like Facebook. The format of the hearing, with limited time for questioning, led to frustration among senators and a lack of nuanced responses. Overall, the discussions highlight the complex interplay between business, politics, and regulation, and the potential consequences of regulatory decisions.

    • Decentralizing power and decision-making on social mediaTech executives like Jack Dorsey propose decentralized approaches to social media, enabling individuals to control their own algorithms and curate content, while projects like BitCloud offer decentralized solutions for quantifying reputation and trust.

      Tech executives, such as Jack Dorsey, are recognizing the need to decentralize power and decision-making on social media platforms. Dorsey's proposal for a protocol approach and Twitter's project to turn social networks into open standards reflects a desire to remove the power from companies and the government to decide who has access to the digital town square. Instead, individuals should have the ability to control their own algorithms and curate their own content. Additionally, projects like BitCloud, which aims to create a decentralized blockchain-based platform, offer a potential solution for quantifying reputation and trust, which could help in determining the value and trustworthiness of content and users. The Suez Canal incident was an unrelated topic discussed in the conversation.

    • Suez Canal incident highlights global supply chain fragility10% of global trade disrupted by Suez Canal incident, underscoring need for more distributed and durable industrial systems using green tech, 3D printing, biomanufacturing, and renewable energy

      The Suez Canal incident serves as a reminder of the fragility of our global supply chain. The incident involved a massive ship getting lodged in the Suez Canal due to a power outage, causing a disruption to around 10% of global trade. This highlights the vulnerability of our centralized global supply chain and the potential significant economic consequences when disruptions occur. The 21st century presents an opportunity to shift the balance of power and sources of production towards a more distributed and durable system using green technology, 3D printing, biomanufacturing, and renewable energy. This can help increase the resilience of our industrial systems and reduce our reliance on centralized production.

    • Increasing vulnerability of global supply chains and the need for resilienceThe recent Suez Canal blockage and nickel mine flooding underscore the importance of resilient and distributed supply chains, which could lead to job creation, resource reduction, and crisis prevention. Long-term infrastructure investments are crucial to create a robust system.

      The global supply chain is increasingly vulnerable to disruptions due to various factors such as extreme weather events, geopolitical tensions, and reliance on specific resources. The recent incident of the Ever Given blocking the Suez Canal and the flooding of a major nickel mine are examples of such disruptions. These incidents highlight the importance of creating more resilient and distributed supply chains, which could lead to the creation of manufacturing jobs and the reduction of reliance on specific resources. The infrastructure bill could be an opportunity to invest in industry-enabling projects, similar to the Manhattan Project and the Apollo mission, rather than just short-term service contracts. The lack of redundancy and inefficiency in the current system can lead to significant price increases and potential crises, as seen with the nickel shortage. Therefore, it is crucial to consider the long-term effects of infrastructure investments and focus on creating a more robust and resilient supply chain system.

    • Emphasizing urgency in climate action and tech growthAddress climate change swiftly to mitigate human cost and invest in SaaS companies for tech growth potential

      Addressing climate change requires prioritizing progress over potential roadblocks, even if those roadblocks are valid concerns. The speaker emphasizes the need for quicker decision-making in green energy projects and the potential human cost of delaying such projects. On a separate note, the tech industry continues to defy expectations with massive valuations and growth, as seen in the Microsoft-Discord acquisition and the success of cloud services like Azure, Google Cloud, and AWS. The speaker's personal investment strategy is now fully committed to Software-as-a-Service (SaaS) companies due to the industry's unprecedented growth. Microsoft's acquisition of Discord may be driven by the competitive threat posed by Slack, as well as the potential to expand its gaming business.

    • Microsoft's acquisition of Yammer and competition from Salesforce's acquisition of SlackMicrosoft's acquisition of Yammer was a strategic move towards cloud, social, and mobile technologies, but they now face competition from Salesforce's acquisition of Slack. On the lighter side, private movie theater rentals have become popular during the pandemic, offering a unique and memorable experience.

      Microsoft's acquisition of Yammer was a strategic move to accelerate their transition into cloud, social, and mobile technologies. However, they now face competition from Salesforce's acquisition of Slack, which could potentially disrupt their plans. On a lighter note, the conversation also touched upon the topic of movie theaters, with some sharing their recent experiences of renting out entire theaters for private screenings. This has become an increasingly popular trend, especially during the pandemic, and offers a unique and memorable experience for families and friends. It seems that despite the challenges faced by traditional movie theaters, they continue to hold a special place in our lives.

    • Individual pressure and government action led to California's accelerated vaccination processPersistent individual efforts and government response ultimately led to faster COVID-19 vaccination progress in California. Excess US vaccines could be used for 'vaccine tourism' or to help developing countries.

      The persistent efforts of individuals and the eventual action by the government led to the accelerated vaccination process against COVID-19 in California. The constant shaming and pressure on Governor Gavin Newsom through social media, along with the President's announcement of moving up the vaccination timeline, ultimately led to Newsom's decision to make vaccines more widely available. Moving forward, there is an excess of vaccines in the US, and there is a suggestion to formalize "vaccine tourism" or use the excess doses to help vaccinate people in developing countries. The discussion also touched upon the contrasting approaches to vaccine distribution between the US and Europe, with the US making faster progress due to less hesitancy in placing orders. The overall conversation highlighted the importance of individual action and government response in addressing a global crisis.

    • Efficiency and Effectiveness in Resource AllocationGovernments must prioritize efficiency and cut through red tape to address equity issues and make a meaningful impact in vaccine distribution and infrastructure projects.

      The efficiency and effectiveness of vaccine distribution and infrastructure projects depend greatly on the ability of governments to allocate resources wisely and avoid bureaucratic delays. The speaker expressed frustration with the slow progress in vaccine distribution in certain countries, particularly in comparison to the UK. The speaker also shared concerns about the lengthy completion times and costs of infrastructure projects, such as the repair of the Bay Bridge in San Francisco. The speaker emphasized the importance of prioritizing efficiency and cutting through red tape to address equity issues and make a meaningful impact. The speaker also touched on the theme of trust, suggesting that the public's faith in governments to manage resources effectively has been eroded. Overall, the speaker's message was one of urgency and a call to action to streamline processes and prioritize results.

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    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484390

    https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30418-9/fulltext

    https://oversight.house.gov/release/new-covid-select-memo-details-allegations-of-wrongdoing-and-illegal-activity-by-dr-faucis-senior-scientific-advisor

    https://fiscaldata.treasury.gov/americas-finance-guide/national-deficit

    https://x.com/KatherineEban

    https://x.com/emilyakopp

    https://www.semafor.com/article/05/28/2024/a-dying-empire-led-by-bad-people-poll-finds-young-voters-despairing-over-us-politics

    https://www.youtube.com/watch?v=nvQTXAgtA6s

    https://s23.q4cdn.com/574569502/files/doc_financials/2025/q1/CRM-Q1-FY25-Earnings-Press-Release-w-financials.pdf

    https://www.investors.com/news/economy/federal-reserve-core-pce-inflation-gdp-q1-jobless-claims-sp-500

    https://www.nytimes.com/live/2024/05/30/nyregion/trump-trial-verdict

    https://www.google.com/finance/quote/DELL:NYSE

    https://www.bloomberg.com/news/articles/2024-05-30/us-gdp-grew-at-softer-pace-as-spending-inflation-marked-down

    Scarlett Johansson vs OpenAI, Nvidia's trillion-dollar problem, the "vibecession," plastic in our balls

    Scarlett Johansson vs OpenAI, Nvidia's trillion-dollar problem, the "vibecession," plastic in our balls

    (0:00) Bestie intros: Recapping "General AI Hospital"

    (2:46) Scarlett Johansson vs. OpenAI

    (14:37) OpenAI's novel off-boarding agreements, ex-employee equity problem, and safety team resignations

    (25:35) Nvidia crushes earnings again, but it faces a trillion-dollar problem

    (40:05) Understanding why economic sentiment is so negative among US citizens despite positive data

    (1:02:36) New study shows plastics in testicles

    Follow the besties:

    https://twitter.com/chamath

    https://twitter.com/Jason

    https://twitter.com/DavidSacks

    https://twitter.com/friedberg

    Follow on X:

    https://twitter.com/theallinpod

    Follow on Instagram:

    https://www.instagram.com/theallinpod

    Follow on TikTok:

    https://www.tiktok.com/@all_in_tok

    Follow on LinkedIn:

    https://www.linkedin.com/company/allinpod

    Intro Music Credit:

    https://rb.gy/tppkzl

    https://twitter.com/yung_spielburg

    Intro Video Credit:

    https://twitter.com/TheZachEffect

    Referenced in the show:

    https://x.com/BobbyAllyn/status/1792679435701014908

    https://x.com/sama/status/1790075827666796666

    https://openai.com/index/how-the-voices-for-chatgpt-were-chosen

    https://www.washingtonpost.com/technology/2024/05/22/openai-scarlett-johansson-chatgpt-ai-voice

    https://x.com/SydSteyerhart/status/1792981291266138531

    https://www.vox.com/future-perfect/351132/openai-vested-equity-nda-sam-altman-documents-employees

    https://x.com/sama/status/1791936857594581428

    https://x.com/ilyasut/status/1790517455628198322

    https://x.com/janleike/status/1790603862132596961

    https://x.com/janleike/status/1791498184671605209

    https://openai.com/index/openai-announces-leadership-transition

    https://nvidianews.nvidia.com/news/nvidia-announces-financial-results-for-first-quarter-fiscal-2025

    https://www.google.com/finance/quote/INTC:NASDAQ

    https://www.morningstar.com/stocks/nvidia-2023-vs-cisco-1999-will-history-repeat

    https://www.fool.com/investing/2024/03/06/is-nvidia-doomed-to-be-the-next-cisco-what-investo

    https://www.elitetrader.com/et/threads/nvidia-and-the-cautionary-tale-of-cisco-systems.379022

    https://chamath.substack.com/p/2023-annual-letter

    https://www.forbes.com/sites/theapothecary/2024/03/23/summers-inflation-reached-18-in-2022-using-the-governments-previous-formula

    https://www.theguardian.com/us-news/article/2024/may/22/poll-economy-recession-biden

    https://fred.stlouisfed.org/series/CCLACBW027SBOG

    https://x.com/KariLake/status/1792986501820850333

    https://www.stlouisfed.org/on-the-economy/2024/apr/how-big-mac-index-relates-overall-consumer-inflation

    https://www.google.com/finance/quote/MCD:NYSE

    https://www.wsj.com/economy/gdp-and-the-dow-are-up-but-what-about-american-well-being-87f90e6d

    https://www.consumerreports.org/health/food-contaminants/the-plastic-chemicals-hiding-in-your-food-a7358224781

    https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2605.2007.00837.x

    https://pubmed.ncbi.nlm.nih.gov/12708228

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559247

    https://pubmed.ncbi.nlm.nih.gov/21524797

    https://academic.oup.com/toxsci/advance-article/doi/10.1093/toxsci/kfae060/7673133

    https://www.youtube.com/watch?v=o6yuYkfNh-k

    https://www.youtube.com/watch?v=EYQjShJxCtM

    https://www.youtube.com/watch?v=r_4jrMwvZ2A

    GPT-4o launches, Glue demo, Ohalo breakthrough, Druck's Argentina bet, did Google kill Perplexity?

    GPT-4o launches, Glue demo, Ohalo breakthrough, Druck's Argentina bet, did Google kill Perplexity?

    (0:00) Bestie Intros: Recapping Phil Hellmuth's birthday weekend

    (7:38) OpenAI launches GPT-4o: better, faster, cheaper

    (29:40) Sacks demos Glue: How AI unlocked his Slack killer

    (40:12) Friedberg walks through his major breakthrough at Ohalo

    (1:01:35) Stanley Druckenmiller bets on Argentina and Javier Milei: strategy, roadmap for the US

    (1:13:54) Jason's bet on Athena, how AI will change company building

    (1:22:21) Google launches AI summaries in search

    Follow the besties:

    https://twitter.com/chamath

    https://twitter.com/Jason

    https://twitter.com/DavidSacks

    https://twitter.com/friedberg

    Follow on X:

    https://twitter.com/theallinpod

    Follow on Instagram:

    https://www.instagram.com/theallinpod

    Follow on TikTok:

    https://www.tiktok.com/@all_in_tok

    Follow on LinkedIn:

    https://www.linkedin.com/company/allinpod

    Intro Music Credit:

    https://rb.gy/tppkzl

    https://twitter.com/yung_spielburg

    Intro Video Credit:

    https://twitter.com/TheZachEffect

    Referenced in the show:

    https://www.pokernews.com/news/2024/05/phil-hellmuth-60th-birthday-bash-las-vegas-45984.htm

    https://x.com/OpenAI/status/1790130703721521305

    https://x.com/OpenAI/status/1790089513387143469

    https://crfm.stanford.edu/helm/mmlu/v1.3.0/#

    https://www.businessinsider.com/inflection-implosion-chatgpt-stall-ai-consumer-chatbot-problem-2024-3

    https://www.opencompute.org

    https://glue.ai

    https://ragie.ai

    https://ohalo.com

    https://www.cnbc.com/2024/05/07/cnbc-exclusive-cnbc-transcript-billionaire-investor-stanley-druckenmiller-speaks-with-cnbcs-squawk-box-today.html

    https://www.forbes.com/sites/theapothecary/2024/03/23/summers-inflation-reached-18-in-2022-using-the-governments-previous-formula

    https://twitter.com/DavidSacks/status/1378034932006592512

    https://www.athenawow.com/jcal

    https://calacanis.substack.com/p/startup-productivity-in-the-age-of

    https://blog.google/products/search/generative-ai-google-search-may-2024

    https://www.youtube.com/watch?v=XEzRZ35urlk

    https://finance.yahoo.com/quote/GOOG

    https://startuptalky.com/apple-failed-products

    In conversation with Sam Altman

    In conversation with Sam Altman

    (0:00) Welcoming Sam Altman to the show!

    (2:28) What's next for OpenAI: GPT-5, open-source, reasoning, what an AI-powered iPhone competitor could look like, and more

    (21:56) How advanced agents will change the way we interface with apps

    (33:01) Fair use, creator rights, why OpenAI has stayed away from the music industry

    (42:02) AI regulation, UBI in a post-AI world

    (52:23) Sam breaks down how he was fired and re-hired, why he has no equity, dealmaking on behalf of OpenAI, and how he organizes the company

    (1:05:33) Post-interview recap

    (1:10:38) All-In Summit announcements, college protests

    (1:19:06) Signs of innovation dying at Apple: iPad ad, Buffett sells 100M+ shares, what's next?

    (1:29:41) Google unveils AlphaFold 3.0

    Follow Sam:

    https://twitter.com/sama

    Follow the besties:

    https://twitter.com/chamath

    https://twitter.com/Jason

    https://twitter.com/DavidSacks

    https://twitter.com/friedberg

    Follow on X:

    https://twitter.com/theallinpod

    Follow on Instagram:

    https://www.instagram.com/theallinpod

    Follow on TikTok:

    https://www.tiktok.com/@all_in_tok

    Follow on LinkedIn:

    https://www.linkedin.com/company/allinpod

    Intro Music Credit:

    https://rb.gy/tppkzl

    https://twitter.com/yung_spielburg

    Intro Video Credit:

    https://twitter.com/TheZachEffect

    Referenced in the show:

    https://twitter.com/EconomyApp/status/1622029832099082241

    https://sacra.com/c/openai

    https://twitter.com/tim_cook/status/1787864325258162239

    https://openai.com/index/introducing-the-model-spec

    https://twitter.com/SabriSun_Miller/status/1788298123434938738

    https://www.archives.gov/founding-docs/bill-of-rights-transcript

    https://twitter.com/ClayTravis/status/1788312545754825091

    https://www.inc.com/bill-murphy-jr/warren-buffett-just-sold-more-than-100-million-shares-of-apple-reason-why-is-eye-opening.html

    https://www.youtube.com/watch?v=snbTCWL6rxo

    https://www.digitimes.com/news/a20240506PD216/apple-ev-startup-genai.html

    https://www.theonion.com/fuck-everything-were-doing-five-blades-1819584036

    https://blog.google/technology/ai/google-deepmind-isomorphic-alphafold-3-ai-model

    In conversation with Sheryl Sandberg, plus open-source AI gene editing explained

    In conversation with Sheryl Sandberg, plus open-source AI gene editing explained

    (0:00) Welcoming Sheryl Sandberg and remembering Dave Goldberg

    (11:10) What led Sheryl to get involved with "Screams Before Silence"; reaction to sexual violence on and after 10/7

    (28:18) Paths forward, documentary decisions, involvement of women in protests

    (53:03) Post-interview debrief

    (59:45) Science Corner: Open-source AI gene editing with OpenCRISPR-1

    Follow Sheryl:

    https://twitter.com/sherylsandberg

    Watch Screams Before Silence:

    https://www.youtube.com/watch?v=zAr9oGSXgak&rco=1

    Follow the besties:

    https://twitter.com/chamath

    https://twitter.com/Jason

    https://twitter.com/DavidSacks

    https://twitter.com/friedberg

    Follow on X:

    https://twitter.com/theallinpod

    Follow on Instagram:

    https://www.instagram.com/theallinpod

    Follow on TikTok:

    https://www.tiktok.com/@all_in_tok

    Follow on LinkedIn:

    https://www.linkedin.com/company/allinpod

    Intro Music Credit:

    https://rb.gy/tppkzl

    https://twitter.com/yung_spielburg

    Intro Video Credit:

    https://twitter.com/TheZachEffect

    Referenced in the show:

    https://twitter.com/fakechamath

    https://www.youtube.com/watch?v=zAr9oGSXgak&rco=1

    https://www.cnn.com/2023/11/20/opinions/sheryl-sandberg-something-we-can-all-agree-on/index.html

    https://news.un.org/en/story/2024/03/1147477

    https://thegrayzone.com/2024/03/07/media-concocts-un-hamas-rape-report/amp/

    https://www.nytimes.com/2024/01/29/world/middleeast/israel-hamas-sexual-violence-un.html

    https://github.com/Profluent-AI/OpenCRISPR

    Meta's scorched earth approach to AI, Tesla's future, TikTok bill, FTC bans noncompetes, wealth tax

    Meta's scorched earth approach to AI, Tesla's future, TikTok bill, FTC bans noncompetes, wealth tax

    (0:00) Bestie Intros: Reservation Tips!

    (5:20) Meta goes scorched earth in AI, why the stock was down despite beating on earnings

    (22:20) Tesla's roadmap, ranking the company's highest-upside bets outside of cars for the next 10 years

    (47:25) FTC bans noncompetes: impact on startups and company formation

    (1:00:33) Besties reminisce on their encounters with Steve Jobs

    (1:10:25) TikTok "divest-or-ban" bill is signed into law: Will China comply? What's it worth without the algorithm? Will a deal get done?

    (1:27:22) Biden's proposed capital gains hikes and a 25% wealth tax for those with $100M+ in assets

    Follow the besties:

    https://twitter.com/chamath

    https://twitter.com/Jason

    https://twitter.com/DavidSacks

    https://twitter.com/friedberg

    Follow on X:

    https://twitter.com/theallinpod

    Follow on Instagram:

    https://www.instagram.com/theallinpod

    Follow on TikTok:

    https://www.tiktok.com/@all_in_tok

    Follow on LinkedIn:

    https://www.linkedin.com/company/allinpod

    Intro Music Credit:

    https://rb.gy/tppkzl

    https://twitter.com/yung_spielburg

    Intro Video Credit:

    https://twitter.com/TheZachEffect

    Referenced in the show:

    https://ai.meta.com/blog/meta-llama-3

    https://huggingface.co/meta-llama/Meta-Llama-3-8B

    https://about.fb.com/news/2024/04/introducing-our-open-mixed-reality-ecosystem

    https://about.fb.com/news/2024/04/meta-ai-assistant-built-with-llama-3

    https://www.cnn.com/2024/04/25/investing/meta-stock-plunges-ai-spending/index.html

    https://www.youtube.com/watch?v=kiMTRQXBol0

    https://twitter.com/AravSrinivas/status/1781099224169320500

    https://wow.groq.com/12-hours-later-groq-is-running-llama-3-instruct-8-70b-by-meta-ai-on-its-lpu-inference-enginge

    https://twitter.com/lauramaywendel/status/1782040453266710551

    https://twitter.com/naveengrao/status/1781491370114633816

    https://twitter.com/winglian/status/1783456379199484367

    https://www.meta.ai

    https://twitter.com/chamath/status/1780302197772952049

    https://electrek.co/2024/03/16/tesla-full-self-driving-beta-v12-finally-rolls-out

    https://www.reuters.com/business/autos-transportation/tesla-cuts-price-full-self-driving-software-by-third-8000-2024-04-21

    https://fortune.com/2024/04/15/elon-musk-tesla-cut-10-percent-global-workforce-14000-employees-slowing-ev-demand

    https://www.reuters.com/business/autos-transportation/tesla-take-shareholder-vote-shifting-incorporation-texas-musk-says-2024-02-01

    https://www.ft.com/content/46aac746-4a54-437f-a0b7-9b81b154c21d

    https://www.google.com/finance/quote/TSLA:NASDAQ

    https://www.cnbc.com/2024/04/24/tesla-stock-up-after-elon-musk-says-new-affordable-ev-models-coming.html

    https://www.tesla.com/blog/master-plan-part-deux

    https://twitter.com/chamath/status/1776663647735218491

    https://digitalassets.tesla.com/tesla-contents/image/upload/IR/TSLA-Q1-2024-Update.pdf

    https://www.cnbc.com/2024/04/25/gdp-q1-2024-increased-at-a-1point6percent-rate.html

    https://palmetto.com

    https://www.youtube.com/watch?v=pja_n8ThDsU

    https://www.fastcompany.com/90972171/cruise-suspends-driverless-vehicle-operations-in-san-francisco-after-dmv-revokes-permit

    https://twitter.com/DavidSacks/status/1777496946263134414

    https://www.nytimes.com/2023/11/03/technology/cruise-general-motors-self-driving-cars.html

    https://thehill.com/business/4615452-ftc-votes-to-ban-non-compete-agreements

    https://www.ftc.gov/news-events/news/press-releases/2024/04/ftc-announces-rule-banning-noncompetes

    https://www.techemails.com/p/steve-jobs-emails-adobes-ceo

    https://venturebeat.com/business/how-steve-jobs-felt-betrayed-by-eric-schmidt-over-googles-android

    https://www.youtube.com/watch?v=CWOt9Cjq2mw

    https://www.theverge.com/2024/4/24/24139036/biden-signs-tiktok-ban-bill-divest-foreign-aid-package

    https://abcnews.go.com/Politics/senate-returns-95b-foreign-aid-package-ukraine-israel/story?id=109506150

    https://www.cnbc.com/2023/12/06/tiktok-parent-bytedance-offers-share-buyback-at-268-billion-valuation.html

    https://www.theinformation.com/articles/bytedance-exploring-scenarios-for-selling-tiktok-without-algorithm?rc=pxkrxo

    https://www.aclu.org/press-releases/senate-reauthorizes-and-expands-section-702-surveillance

    https://twitter.com/DavidSacks/status/1783220583075111401

    https://www.wsj.com/tech/tiktok-ban-chinese-owners-bytedance-1a857a06

    https://x.com/MsMelChen/status/1783524423963697262

    https://x.com/Jason/status/1783556155924705388

    https://x.com/Jason/status/1783604248569360516

    https://www.atr.org/biden-calls-for-44-6-capital-gains-tax-rate-highest-capital-gains-tax-since-its-creation-in-1922

    https://home.treasury.gov/system/files/131/General-Explanations-FY2025.pdf

    https://www.bloomberg.com/news/articles/2024-04-24/tax-on-rich-to-save-social-security-popular-with-swing-state-voters-poll

    https://balajis.com/p/all-it-takes-is-all-you-got

    https://twitter.com/maceskridge/status/1783290784311058788

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