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    How Smell, Taste & Pheromone-Like Chemicals Control You

    enJune 21, 2021
    What is chemical sensing and its effects on our biology?
    How does diet influence taste preferences and cravings?
    What exercises can enhance chemical sensing and cognition?
    Why is nasal breathing important for cognitive function?
    How do taste receptors function outside of the tongue?

    Podcast Summary

    • Enhancing Chemical Sensing for Better Health and VisionOur ability to detect chemicals in our environment can impact our biology and mood. Improving chemical sensing can enhance cognition, learning, memory, and vision. Spending time outdoors and consuming lutein may also boost vision and offset age-related degeneration.

      Chemical sensing is our ability to detect odors and tastes in our environment and can have a powerful effect on our biology, including our mood, metabolism and hormones. While human pheromones are controversial, there are chemicals released through tears, sweat and breath that modulate the biology of other individuals. The episode provides tools and protocols to enhance chemical sensing and improve cognition, learning and memory. Near far viewing exercises and spending two hours outside per day can also improve vision and offset nearsightedness. Additionally, lutein may help offset age-related macular degeneration and vision loss as we get older. The similarities between our biology and that of other animals are also highlighted.

    • The Fascinating Connection Between Chemicals and Human SensesOur senses pick up physical stimuli, including chemicals, which can affect our biology and lead us to take action. This connection is both deliberate and non-deliberate, from smelling smoke to consuming food.

      Humans have a remarkable color vision that makes color perception a fascinating subject. Our senses pick up physical stimuli like light, sound waves, pressure, touch, scratch, tickle, etc. Chemicals are another way we sense our environment. We often bring them into our bodies through deliberate and non-deliberate actions. Certain chemicals are made by people with their bodies, like pheromones that can change our biology. We can detect these chemicals through our nose, mouth, or eyes. For example, smelling smoke can cause us to take action, while intentionally consuming food will bring chemicals from it into our body.

    • The Power of Chemicals in Tears and SmellsTears and smells can affect our biology and interpersonal communication, as chemicals from others powerfully modulate our internal state. Olfactory neurons respond to innate odor responses, suggesting a hardwired aspect to the way we smell the world. Understanding this can lead to new insights in communication.

      Chemicals in tears can affect the biology of other individuals, as shown by a study where men's hormone levels and brain activity were affected by the tears of women. This illustrates how chemicals made by others can powerfully modulate our internal state. Smell plays a role in this process: the olfactory neurons responsible for sensing different odorant compounds are connected to pathways in the brain that respond to innate odor responses. This means that we have some hardwired aspects to the way we smell the world. Understanding how chemicals affect our biology and interpersonal communication, including using smells, is a super interesting area of research.

    • The Impact of Smell on Our Brain and BehaviorOur sense of smell affects our alertness, memory, and learning abilities. Breathing through the nose is beneficial and odors impact us through innate, learned, and possible pheromone effects.

      Smelling compounds in our environment triggers innate pathways in our brain, leading to heightened alertness and threat detection. Our olfactory system imprints memories very early on and creates powerful associations with people, places, and contexts. The act of smelling, sniffing, and inhalation powerfully impacts how our brain functions and what we can learn and what we can't learn. Breathing through our nose is beneficial and advantageous compared to mouth breathing, which has several disadvantages. Odors impact us through three paths: innate behaviors, learned responses, and true pheromone effects. The accessory olfactory pathway, responsible for true pheromone effects in other animals, is still controversial in humans.

    • The Power of Nasal Breathing for Brain Function and HealthNasal breathing can improve brain function, jaw structure, immune system, and sensory perception. Incorporating deep inhales and limiting mouth breathing can enhance focus and learning abilities, making nasal breathing a valuable tool for cognitive performance.

      Breathing through the nose can have positive effects on brain arousal, attention, and the ability to learn and remember information. Nasal breathing is beneficial for jaw structure and immune system function. Sniffing, or inhaling more deeply through the nose, can increase sensitivity to smell and taste. Practicing nasal breathing and incorporating more deep inhales can be helpful for staying alert and focused during focused work or learning. Restricting to nasal breathing is also better for learning compared to breathing through the mouth or a combination of both. Becoming a nasal breather can be a powerful tool for improving overall cognitive function.

    • Enhance Your Brain Power with Nasal Breathing and Sense of SmellPracticing nasal breathing and enhancing your sense of smell can wake up your brain, improve perception of smells, and enhance enjoyment while eating. Try a simple experiment of inhaling an orange's scent to boost your sense of smell.

      There are multiple ways to wake up your brain, including the use of smelling salts, which trigger the fear and arousal systems of the brain. However, inhaling through your nose and doing nasal breathing is a subtler way of alerting your brain. You can enhance your sense of smell by practicing or enhancing your ability to sniff. By doing an experiment of taking an orange, smelling it, doing 10 or 15 inhales and exhales through your nose, and smelling it again, you can significantly increase your perception of the smell. You can also train your sense of smell to become very astute in distinguishing one particular odor or combinations of odors. Enhancing your sense of smell can enhance your sense of pleasure and enjoyment while eating.

    • The Power of Smelling and Tasting Food for Your HealthPracticing mindfulness with sniffing and inhaling food can improve your olfactory and taste sensitivity, help distinguish food preferences, and indicate brain health while dopamine and exercise regenerate olfactory neurons.

      Smelling and tasting food is not just a mindfulness practice, it can also increase the sensitivity of your olfactory and taste system. Through occasional practice of sniffing, inhaling, and attention, you can radically change your relationship to food, ingesting those foods as well as becoming more discerning about which foods you like and which ones you don't like. Having a sensitive sense of smell and taste can indicate something about brain health, and losing these senses can be an early sign of diseases like dementia. Exercising regularly and having high dopamine levels can help regenerate olfactory neurons, indicating the importance of taking care of your brain through simple practices like smelling your food.

    • The Connection between Olfactory Neurons and Exercise, Smell, and Social InteractionTo maintain a healthy olfactory system, engage in exercise, social interactions, and positive interactions with odorants. Sniff more and inhale more to keep it tuned up. Olfactory dysfunction may indicate a traumatic brain injury, and recovering your sense of smell may indicate improved sensory performance.

      Our olfactory neurons are special in that they continuously replenish throughout life, and their regeneration is positively correlated with exercise, social interactions, and interactions with odorants. Dopamine is a powerful trigger of the establishment of new neurons and their migration into the olfactory bulb and the ability to smell. As we age, we lose our sense of smell, which is correlated with a loss of other neurons in the retina and ear. To keep the olfactory system tuned up, interact with positive odors, sniff more, and inhale more. Olfactory dysfunction is common in traumatic brain injury, and recovery of sense of smell can be one indicator of regaining sensory performance.

    • The Fascinating Science of Our Sense of SmellOlfactory training and inhaling with focus can improve brain function. Smelling salts aid force development. Sense of smell in dreams is possible, but response to odors is diminished during REM sleep. Sniff reflex has clinical use in assessing brain function.

      Enhancing your sense of smell post-injury through olfactory training can create new neurons by interacting with things that have an odor, improving dopamine dopaminergic signaling. Inhaling more, focusing on the inhale, and testing your sense of smell and taste will help to activate and tune up this system. Ammonia inhalants or smelling salts have been shown to have a psyching up effect that increases maximal force in force development in various movements. Contrary to the myth, we are capable of smelling things in our dreams, but our ability to wake up in response to odors is diminished during rapid eye movement sleep. Clinicians can use sniffing reflex to assess the brain's capacity to recover from deep unconsciousness or brain death.

    • The Science of Sensory Stimulation for Brain ArousalOur sensory experiences are unique due to genetics, and certain odors and tastes can evoke deep biological responses. However, caution should be exercised with specific compounds as they can damage the olfactory pathway and vision.

      Olfactory stimulation is a prominent way to assess the brain's capability of arousal, but specific compounds like peppermint or ammonia smelling salts should be used with caution as they can damage the olfactory pathway and vision. The nervous system can evoke wake up responses to a near-infinite number of stimuli which involve adrenaline and epinephrine. Sensory experience varies from person to person due to genetics. Some people have a gene that makes them sensitive to certain odors, causing them to feel disgusted. Certain tastes can evoke deep biological responses, including hormonal responses. While musky and musty scents may be pleasant to some, they can be noxious to others depending on the concentration.

    • Understanding Our Sense of Taste and SmellOur genes influence our sense of taste and smell. The five basic tastes, sweet, salty, bitter, sour, and umami, are detected by specific receptors in our tongue. The idea that different parts of the tongue detect different tastes is a myth. Sweet foods signal energy or sugars, so it is essential for us to detect them.

      Our sense of smell and taste are influenced by the genes we express in our sensory neurons. The five basic tastes are sweet, salty, bitter, sour, and umami, and they each have specific receptors in our tongue that respond to particular chemicals. The myth that different parts of the tongue harbor different taste receptors is completely false. Our taste receptors are evenly distributed throughout the tongue, and any differences in sensitivity likely reflect the overall receptor density or something going on in our brain. Sweet food signals the presence of energy or sugars, making it essential for us to detect the rapid energy source in our food.

    • The Importance of Taste Receptors in Our Food IntakeOur taste receptors play a crucial role in identifying nutrients and toxins in our food, helping us make informed choices for a healthy diet.

      Our taste receptors, such as sweet, salty, bitter, sour, umami, and possibly fatty acids, are crucial in detecting nutrients and toxins, and ensuring we consume safe and vital substances for our body. For instance, bitter receptors help in identifying poisonous foods, while sweet receptors signal the presence of necessary electrolytes and sensory cells that allow nerves to be electrically active. Sour receptors can detect spoiled or fermented food, which can be poisonous to our system, and trigger the pucker response to prevent ingestion. Moreover, savory receptors indicate the presence of amino acids that our body needs to survive. Understanding the role of taste receptors can help us make informed choices about our food intake.

    • Understanding the Importance of Taste Buds in Our Digestive SystemTaste buds in our mouth and tongue play a crucial role in our digestive system by providing a chemical sensing apparatus that is responsible for tasting different flavors. Training and paying attention to what we eat can enhance our ability to taste, which can affect our desire to eat more. Even though burnt tongues can reduce our sense of taste, the neurons can regenerate themselves.

      The mouth and tongue are an important part of the digestive tract, equipped with an amazing chemical sensing apparatus known as taste buds. These buds contain receptors for sweet, salty, bitter, umami, sour and possibly fat. The ability to sense fat in our mouth is critical, and what we sense impacts our motivation to eat more through the vagus nerve sending signals to the brain to secrete dopamine. The ability to taste is highly subject to training, and one can enhance their ability to taste by paying attention to what they're trying to taste. Burnt tongues can reduce sense of taste for all tastes, but the neurons can replenish themselves.

    • Developing a Sensitive Palate and the Science of Taste PerceptionOur ability to detect and appreciate different tastes can be improved through experience. However, individual differences in taste perception and the influence of marketing on flavor descriptions should also be considered.

      The ability to detect nuances in taste and develop a sensitive palate is amenable to behavioral plasticity. Taste receptors vary across animals, with meat-eating animals having more umami receptors and herbivores having more sweet receptors. Humans with different diets may also have different sensitivity to certain flavors. Developing a nuanced palate can also help with assessing wines and foods, as there are real differences in taste and aroma that can be detected. However, menu-based and marketing-based descriptions of flavors may not always be accurate. The olfactory cortex plays a key role in making sense of taste and determining its utility. The neural circuitry for taste is unique and varying across individuals.

    • The complex relationship between food, taste, and our biologyOur diet can impact our taste preferences and food cravings, with meat enhancing umami flavors and plants increasing the desire for sweet foods. Taste receptors are present in various tissues, affecting sensuality and reproductive behaviors, while our nervous system's core function drives us towards good and away from bad. Further research can shed more light on the intricate connection between food and our bodies.

      Different diets can affect our taste preferences and food cravings. Eating meat can enhance our ability to detect umami flavors, while a plant-based diet can increase our desire for sweet foods. Taste receptors are not only present on the tongue, but also in other tissues such as the gut and reproductive system. This may explain the association between certain foods and sensuality or reproductive behaviors. The relationship between food and taste is deeply rooted in our biology and the nervous system's core function of moving towards things that are good for us and moving away from things that are bad for us. Emerging research in this area may shed more light on the connection between food and our bodies.

    • The Relationship Between Taste and PleasureTaste receptors in our body affect not only our sensory experience of food but also our visceral pleasure. The Maillard reaction provides a basis for flavor, while our nervous system plays a role in determining our taste preferences.

      Our taste receptors are not just limited to the tongue but are expressed in other tissues including the gonads and respiratory system. The presence of taste receptors on the gonads can bridge the gap between our sensory experience of food and the visceral pleasure we derive from it. The Maillard reaction is a chemical reaction that occurs when sugar and amino acids interact and create a ketones group, resulting in a savory flavor. This reaction is important as it provides a chemical basis for how we taste food. Our whole nervous system is tuned to be drawn towards repetitive or repelled by aversive behaviors, and this push-pull exists even in our taste preferences.

    • The Link between Smell and Taste in Processed FoodsProcessed foods are designed to trigger dopamine response by imitating natural foods. Miracle berry changes sourness to sweetness, altering receptor activity. Actual food taste drives different brain pathways, and sugar avoidance occurs when mice swap sweet receptors for bitter ones.

      The relationship between smell and taste is close, and when activated in a particular way, it triggers the activation of multiple brain areas. Manufacturers create processed foods to trigger dopamine response by creating textures and designs that imitate natural foods. These foods stimulate the neurons in your gut, triggering the release of dopamine that makes you seek more of it, regardless of the taste. Miracle berry is a relatively inexpensive way to change the perception of sourness to sweetness, and it does that by changing the activity of the receptors in the mouth and tongue. Lastly, scientists have shown that the actual food's taste drives different pathways in the brain, and when mice swapped out sweet receptors for bitter ones, they avoided sugar water.

    • The Science of our Sensory WorldOur taste and smell perceptions can be altered through various means, including chemicals and pheromones. The synchronicity of menstrual cycles in women may depend on timing and phase.

      Our taste experiences are dependent on the taste receptors on our tongue, and we can change our perception of food using miracle fruit. Pheromonal effects have been established in animals, and the Coolidge effect shows that both males and females can regain their ability to mate with the presence of a new partner's scent. Chemical signaling between humans has been debated, but there is evidence for the synchronization of menstrual cycles among women. The timing of this synchronization, however, depends on the phase of the menstrual cycle that the women are in.

    • Chemical Signaling Between Humans: Its Importance and LimitationsChemical signaling between humans is a complex process influenced by various factors such as gender and individual differences. While it plays a crucial role in mate selection and reproductive biology, there is still limited knowledge about its full impact and underlying mechanisms.

      Chemical signaling between humans is a reality, including the detection of scents and odors from other individuals. Women seem to be better at detecting odors than men, and synchronization of menstrual cycles through chemical signals is possible, although clashes can happen too. While the existence of pheromones is likely, scientists are reluctant to call chemical signaling a true pheromonal effect unless a molecule can be identified as the source of the impact. Chemical signaling also plays a crucial role in reproductive biology, as it helps to detect suitable partners and avoid risks. More research is needed in this field, but there are already some interesting studies and reviews published.

    • The Science Behind Our Chemical EvaluationsThe Science Behind Our Chemical Evaluations  Humans, like animals, evaluate and respond to their chemical environment through inhaling, ingesting, and rubbing. Pay attention to these behaviors to understand their influence on our interactions with others.

      Humans are constantly evaluating the chemicals emitted by other people through interactions like handshakes and rubbing their own eyes. This subconscious behavior is similar to bunting in animals, where they rub their scent glands on others to mark them. Humans not only detect facial expressions but also hormone status, smell, and pheromones, among other signals. The handshake eye rub experiment shows that humans are reflexively wiping themselves with other people's chemicals to evaluate their chemical environment. This behavior illustrates the extent to which humans, like other animals, evaluate and respond to their chemical environment through what they inhale, ingest, and rub on themselves. Thus, it's essential to pay attention to these behaviors in our environment and understand their influence on our interactions with others.

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    I'm honored to share Episode 10, the final episode of Season 1 of Perform with Dr. Andy Galpin. Dr. Andy Galpin is a tenured full professor at California State University, Fullerton, where he co-directs the Center for Sport Performance and leads the Biochemistry and Molecular Exercise Physiology Laboratory. Andy is both a friend and a colleague, and I'm delighted to have assisted in the creation of this podcast. I'm certain you'll both enjoy and learn from it. Season 1 featured 10 episodes, where Dr. Galpin covered everything from building strength, the importance of strength for long-term health, the science of breathing, the benefits of sleep extension, genetic testing for personalized training, and nutrition for injury recovery. While we have Episode 10 of Perform with Dr. Andy Galpin here, please be sure to follow Perform with Dr. Andy Galpin on your preferred platform to listen to all the episodes from Season 1 and to get notified when Season 2 is released. Show notes for this episode can be found at performpodcast.com. Timestamps 00:00:00 Introduction from Dr. Andrew Huberman 00:01:08 Brain Health & Injury   00:05:06 Sponsors: LMNT & Continuum   00:08:16 Nutrition & Supplements for Brain Injury   00:12:44 Brain Injury Categories, Traumatic Brain Injury (TBI), Concussion   00:17:09 Brain Injury Pathophysiology   00:22:16 Burst Capillaries, Initial TBI Response   00:30:03 Delayed TBI Response, Neuroinflammation   00:34:19 Sponsors: Momentous & Maui Nui   00:36:52 Creatine Monohydrate; Second Impact Syndrome   00:41:52 Strength of Evidence Scale, Creatine   00:47:15 Creatine Doses, Frequency, Adverse Issues; Food Sources   00:53:22 Sponsors: AG1 & David Protein   00:56:05 Fish Oil, DHA, EPA   01:00:38 EPA & DHA Dosage, Timing, Adverse Issues; Food Sources; Omega-3 Index   01:04:46 Vitamin B2 (Riboflavin), Vitamin B   01:08:57 Riboflavin Dosages, Timing; Food Sources   01:11:25 Choline   01:18:37 Choline Supplements & Food Sources, Alpha GPC, Dosage   01:21:30 Branched-Chain Amino Acids (BCAAs), Sleep   01:25:04 BCAAs Dosage, Whole Food Sources   01:28:02 Magnesium   01:31:20 Magnesium Dosage, Timing, Supplements, Adverse Issue; Food Sources   01:33:09 Blueberry Anthocyanins   01:35:28 Anthocyanins Dosage; Food Sources   01:37:17 Caffeine & Brain Injury Recovery   01:38:50 Perform Episodes, Perform Newsletter, Acknowledgements   01:41:19 Zero-Cost Support, YouTube, Spotify & Apple Subscribe & Reviews, Sponsors, YouTube Feedback, Social Media   01:42:56 Conclusion by Andrew Huberman   Disclaimer
    Huberman Lab
    enAugust 14, 2024

    Dr. Layne Norton: Tools for Nutrition & Fitness

    Dr. Layne Norton: Tools for Nutrition & Fitness
    In this episode, my guest is Dr. Layne Norton, Ph.D., one of the world’s top experts in nutrition and training for physical fitness. We discuss how to evaluate scientific evidence and the validity of different practices aimed at achieving fat loss, muscle strength and hypertrophy, microbiome health, vitality, and longevity. We explore many hotly debated topics, including fasting, seed oils, saturated fats, sugar, red meat, artificial/low-calorie sweeteners, and GLP-1 agonists (e.g., Ozempic). Additionally, we delve into the timing of protein and carbohydrate intake relative to fasting and exercise, fat loss and sleep, and the benefits of dietary protein and fiber on overall health. We also discuss how to accelerate hypertrophy and fat loss, improve strength, whether we need to train to “failure,” how to enhance exercise recovery, and how to manage pain. We cover training before versus after age 50, whether metabolism changes with age, and the connection between muscle health and longevity. We also address why certain behaviors and supplements might work for some people but not others. Listeners to this episode will benefit greatly from Layne’s science-based expertise on a wide range of topics, including health, nutrition, and fitness. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Mateina: https://drinkmateina.com/huberman Eight Sleep: https://www.eightsleep.com/huberman Maui Nui: https://mauinuivenison.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Dr. Layne Norton 00:01:49 Sponsors: Mateina, Eight Sleep, Maui Nui 00:06:39 Science-Based Evidence, Mechanism vs. Outcome 00:14:31 Meta-analysis, Methods, Evidence Quality 00:22:45 Evidence Hierarchy, Randomized Controlled Trials, Cohort Data 00:33:53 Sponsor: AG1 00:35:05 “Don’t Turn Your Brain Off”; Protein Synthesis 00:42:01 Protein Synthesis, Refractory Response; Resistance Training   00:46:05 Protein Intake, Intermittent Fasting & Training 00:54:52 Tool: Total Protein Intake, Distribution & Protein Synthesis 01:00:25 Muscle Quality, Protein Remodeling, Muscle Growth 01:05:34 Sponsor: LMNT 01:06:46 Early vs. Late Time-Restricted Eating; Fasting Blood Glucose & HbA1c 01:10:30 Carbohydrate Timing, Individual Response, Placebo; Tool: Tracking Diet 01:19:50 “The Norton Method”; Tool: Consistency 01:25:16 Resistance & Cardiovascular Training; Competition; Immune System & Rest 01:33:50 Mind & Body Effects, Stress; Belief Effects 01:41:30 Training to Failure, Reps in Reserve, Hypertrophy & Strength Training 01:50:24 Fatigue & Training to Failure, Speed, Strength Training 01:59:06 Tool: Training After 50, Consistency 02:09:12 Fat Cells, Diabetes, Exercise 02:16:50 Metabolism & Age-Related Changes?, Appetite 02:23:17 Ozempic, Mounjaro, GLP-1 Agonists, Lean Mass, “Food Noise” 02:33:42 GLP-1 Agonists, Judgement & Obesity 02:40:19 Sugar, Excess Calories, Body Weight 02:49:16 Satiety, Sugar & Calorie Budget 02:54:56 Tool: Individualization, Context & Diet Psychology 02:57:22 Seed Oils, Butter, Olive Oil 03:06:56 Red Meat, Carcinogenic?; Simple Diet; Fiber Benefits 03:13:43 Saturated Fat, Cholesterol; Seed Oils 03:18:41 Artificial & Low-Calorie Sweeteners, Insulin, Appetite 03:29:06 Artificial & Low-Calorie Sweeteners, Gut Microbiome; Cancer 03:37:58 Tools: Training Recovery, Glycogen Replenishment; Stress & Activity 03:45:56 Collagen Supplementation, Skin & Nails, Whey Protein 03:57:00 Evidence-Based Approach 04:01:41 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures
    Huberman Lab
    enAugust 12, 2024

    Dr. Martha Beck: Access Your Best Self With Mind-Body Practices, Belief Testing & Imagination

    Dr. Martha Beck: Access Your Best Self With Mind-Body Practices, Belief Testing & Imagination
    In this episode, my guest is Dr. Martha Beck, Ph.D., a Harvard-trained sociologist, bestselling author, and one of the world’s foremost experts on personal exploration and development.  Dr. Beck shares specific frameworks and practices to tap into your unique and deepest desires, core truths, and best life direction—all elements that comprise your authentic self. She also explains how to align your work and relationships of all kinds with your true self and how to embrace the discomfort and process of leaving unhealthy relationships. We discuss how to deal with negative thoughts and emotions, grapple with societal norms, and improve body awareness to gauge your inner truth. We also discuss codependency and self-abandonment - and how to exit and recover from these experiences.  By the end of the episode, you will have learned numerous practical tools to access your best self and live a richly fulfilling life.  Access the full show notes for this episode at hubermanlab.com. Dr. Beck's Wayfinder Life Coach Training: https://marthabeck.com/life-coach-training Thank you to our sponsors AG1: https://drinkag1.com/huberman BetterHelp: https://betterhelp.com/huberman Helix Sleep: https://helixsleep.com/huberman LMNT: https://drinklmnt.com/huberman Waking Up: https://wakingup.com/huberman Timestamps 00:00:00 Dr. Martha Beck 00:01:34 Sponsors: BetterHelp, Helix Sleep & LMNT 00:05:34 Tool: Perfect Day Exercise 00:15:31 “Clear Eyed”, Male vs. Female 00:23:31 Family & Work; Directed Attention & Miracles 00:30:21 Sponsor: AG1 00:32:10 Unease, Restlessness & Guilt; Life Worth, Fear 00:37:22 Accessing the Subconscious; Compassionate Witness Self 00:46:16 Finding Self, Suffering, Anxiety; Tool: “KIST”, Self-Parenting 00:54:01 Self, Radiance, Death; Awakening 00:59:14 Suffering & Compassionate Attention 01:02:10 Challenging Internal Thoughts, Understanding Truth, Body & Mind; 01:08:44 Sponsor: Waking Up 01:10:20 Western Society & Pressure 01:18:30 Tool: Sensing Truth in Body; Meditation, “Stopping the World” 01:25:02 Energy, Magnetoreception, Pet’s Death 01:33:49 Lying to Ourselves, Addiction 01:38:18 Tool: “Integrity Cleanse”, Lies; The Light 01:47:32 Relationship with Loss; Love, Self-Abandonment & Codependency 01:55:10 Romantic Relationships; Jobs & Family 02:02:06 Hurting Others, Relationship Imbalance 02:06:55 Tool: True Empathy 02:11:26 “Happiness is an Inside Job”, Codependency 02:18:58 Live Your Joy, Western Society 02:24:41 Relationships, Love & Integrity, “Feeling Good By Looking Weird” 02:30:42 “I Like It!”, Punk Rock Music, Love 02:34:24 Honesty & Essential Self; Helping People & Healers 02:42:12 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures
    Huberman Lab
    enAugust 05, 2024

    AMA #18: Cold Therapy Advice, Skin Health Tips, Motivation, Learning Strategies & More

    AMA #18: Cold Therapy Advice, Skin Health Tips, Motivation, Learning Strategies & More
    Welcome to a special edition of the 18th Ask Me Anything (AMA) episode, part of Huberman Lab Premium. This episode is a recording of the live stream AMA, exclusive to our Premium members. We've decided to make the full-length version available to everyone, including non-members of Huberman Lab Premium. Huberman Lab Premium was launched for two main reasons. First, it was launched in order to raise support for the main Huberman Lab podcast — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation and other donors. If you're not yet a member but enjoyed this full-length livestream AMA, we invite you to join Huberman Lab Premium. By subscribing, you'll gain access to exclusive benefits including our regular monthly full-length AMA episodes, AMA transcripts, podcast episode transcripts, early access to live events and more. Additionally, a significant portion of your membership proceeds contributes to advancing human scientific research. You can learn more about the research we were able to support in our Annual Letter 2023. If you're a Huberman Lab Premium member, you can access the transcript for this AMA episode here. Timestamps 00:00 Introduction & Announcements 00:15 Supporting Mental & Physical Health Research 01:56 Exciting New Research Initiatives 03:39 Skin Health & Appearance 14:46 Cold Therapy Benefits & Guidelines 21:18 Self-Motivation Strategies 27:05 Understanding REM Sleep 28:45 Morning Routine: Exercise & Cold Exposure 29:17 The Importance of REM Sleep 29:49 Non-Sleep Deep Rest (NSDR) Protocols 31:27 REM Sleep Rebound & Compensation 32:55 Impactful School Strategies for Learning 34:19 Meditation & Micro Gaps in Learning 39:13 Physical Activity & Learning 41:01 Exploring Shilajit & Testosterone 47:51 Writing Process & Overcoming Obstacles 51:32 Addiction & Recovery Resources 53:47 Closing Remarks & Gratitude Disclaimer & Disclosures
    Huberman Lab
    enAugust 02, 2024

    Dr. Peter Attia: Supplements for Longevity & Their Efficacy

    Dr. Peter Attia: Supplements for Longevity & Their Efficacy
    In this episode, my guest is Dr. Peter Attia, M.D., a Stanford and Johns Hopkins School of Medicine-trained physician expert in improving human healthspan and lifespan. Dr. Attia is also the host of The Drive podcast and author of the best-selling book Outlive.  We discuss the NAD pathway in human cells and its possible links to aging and health. We evaluate how supplementation can augment molecules in the NAD pathway; we compare NAD, NMN, and NR, different routes of administration, their safety, and bioavailability. Then, we discuss the broader research and clinical literature on longevity to decide if supplementation with NAD, NR, NMN, rapamycin, or resveratrol can indeed extend lifespan.  Finally, we each describe our supplement regimens and compare the role of supplementation to behaviors such as sleep, nutrition, and exercise for longevity. We also discuss whether tests of biological age are true indicators of aging and whether normal radiation levels increase cancer risk.  Listeners of this episode will learn if supplements purported to improve lifespan show any efficacy and the behaviors and other factors that can prevent disease and extend lifespan. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/huberman Levels: https://levels.link/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps 00:00:00 Dr. Peter Attia, NAD Pathway 00:02:31 Sponsors: LMNT, Levels & Eight Sleep 00:06:38 Categories of Longevity Approaches 00:17:22 Peter’s Supplements; Rapamycin & Research Data 00:25:01 NAD Pathway: Energy & DNA Repair; Knock-Out & Knock-In, Klotho 00:30:35 Sponsor: AG1 00:32:25 Yeast, Sirtuins, Caloric Restriction & Lifespan 00:38:56 Sirtuins, Transgenic Mice, Gender & Lifespan 00:43:42 DNA Repair, Sirtuins, Cancer; Resveratrol 00:53:31 Perform with Dr. Andy Galpin Podcast 00:54:18 NAD & NADH, Reactive Oxygen Species (ROS), Mitochondrial Health 01:02:17 NAD vs NR vs NMN Supplementation; IV & Oral Routes 01:11:33 NR vs. NMN, Doses, Side Effects; Interventions Testing Program 01:17:43 Fatty Liver Disease & NR; NMN & Glucose; Clinical Significance 01:25:17 Safety & FDA, NMN & NR Supplementation; Skin Cancer Benefits 01:30:38 Longevity, NR & NMN Supplementation, Inflammation 01:41:00 Rapamycin & Immune Function 01:44:37 Biological Aging Tests, Chronologic & Biologic Age; Vigor  01:55:24 Radiation & Cancer Risk 01:58:12 Tool: Self-Care in 50s-70s & Aging; Energy Decline 02:07:12 Tool: Exercise Timing & Energy Levels 02:11:22 Peter’s Supplements 02:18:46 Andrew’s Supplements 02:24:34 Tool: Supplement Use vs. Critical Behaviors; Titanic Analogy  02:26:52 NAD Pathway Supplementation for Longevity? 02:28:52 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Social Media, Neural Network Newsletter Disclaimer
    Huberman Lab
    enJuly 29, 2024

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    https://180nutrition.com.au/

    Stu

    This week, I'm excited to welcome Lee Holmes. Lee is a nutritionist, yoga teacher, whole foods chef, and author of multiple books with a whole food focus. She's the founder of the website Supercharged Food that aims to help you feel amazing and improve your health through diet, nutrition, and healthy lifestyle tips. In this episode, we discuss gut health, why it's so important, how we can determine if we might have issues, and then the steps to take to get us back on track. Lee is a wealth of knowledge, we have great fun, and I know you'll enjoy our conversation. Over to Lee.

    01:21 Hey, guys. This is Stu from 180 Nutrition and I'm delighted to welcome Lee Holmes back to the podcast. Lee, how are you?

    Lee

    01:28 Hi. I'm well. How are you, Stu

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    01:30 Very well, thank you. Very well. Thanks for coming back. It was a while ago that we spoke, so I'm just aware that we may have a few new listeners that may not know who you are, so before we get stuck into the questions, could you just tell us a little bit about yourself please?

    Lee

    01:46 Sure. I'm Lee Holmes. I'm a nutritionist, a whole food chef, and I teach yoga and meditation. I have a website called SuperchargedFood.com, which I share a lot of recipes on there and I've written about nine books now.

     

    For full transcript and interview:

    https://180nutrition.com.au/180-tv/lee-holmes-interview/

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