Logo
    Search

    Lilly weight loss drug succeeds in sleep apnea trial

    enApril 17, 2024

    Podcast Summary

    • Promising results for Eli Lilly's weight loss therapy Tirzepatide in phase three trialsEli Lilly's Tirzepatide shows promise in treating obesity and obstructive sleep apnea, potentially impacting companies in the sleep apnea industry and broader healthcare sector.

      Eli Lilly's weight loss therapy Tirzepatide showed promising results in phase three trials for obesity and obstructive sleep apnea, potentially impacting companies like ResMed, Inspire Medical Systems, Philips, and Jazz Pharmaceuticals. Meanwhile, the market is adjusting to the new Fed funds rate landscape, with the implied floor for the funds rate being in the 4% area. Despite this, BMO strategist Brian Belsky suggests that higher interest rates may not be detrimental to stock investors, as some of the strongest S&P 500 performance periods have occurred during rising or higher interest rate environments.

    • Market transition causing volatility and uncertaintyDespite some positive earnings reports and collaborations, the market is experiencing volatility and uncertainty due to the transition to a more normal rate structure, causing some funds to underperform and investors to pull out.

      The market is facing a challenging transition from easy money investing to a more normal rate structure, leading to potential volatility and uncertainty in the coming months. This was highlighted by Abbott Labs' better-than-expected Q1 earnings but narrowed sales growth guidance, as well as Travelers Companies' earnings miss due to catastrophe losses. Elsewhere, Cathie Wood's ARK Innovation ETF fell below its 200-day moving average for the first time since late 2023, and investors pulled $1.4 billion from the fund this year. Meanwhile, Walmart announced a new collaboration with the Jessica Simpson brand, and the retail sector continues to be a bright spot. Despite these developments, the broader market remains in a downtrend, with many ETFs trading below their 200-day moving averages.

    • Impact of Rising Rates on Housing Finance IndustryRising interest rates are affecting MSR values positively but decreasing refinancing levels, leading to increased overall operating margins. However, if rates fall below 4.5%, origination volumes can still be maintained. Above 4.5% and volatile conditions put pressure on single multifamily origination volumes and stress on credit metrics.

      The current rising interest rates are having a significant impact on the housing finance industry, particularly on mortgage servicing rights (MSR) and origination volumes. According to Wedbush, the positive effect of higher rates on MSR values is being offset by lower refinancing levels, leading to decreased amortization costs and increased overall operating margins. However, if the US 10-year treasury yield falls below 4.5%, most housing finance companies covered by Wedbush can still maintain acceptable levels of origination volumes and gain margins. On the other hand, with the 10-year above 4.5% and volatile rate conditions, there is expected pressure on single multifamily origination volumes and stress on multifamily credit metrics. For originators like Guild Holdings, Rocket Companies, and UWM Holdings, climbing rates are likely to slow the purchase market and refi market, resulting in lower gain on sales margins. Overall, the housing finance industry is facing challenges due to the current interest rate environment, and companies will need to adapt to these changing conditions.

    Recent Episodes from Wall Street Breakfast

    Tech stocks recover, South Korea grants and Micron's Q3

    Tech stocks recover, South Korea grants and Micron's Q3
    Nasdaq, S&P snap 3-day losing streak as Nvidia rebounds (0:28), South Korea to start granting aid to chip manufacturers (3:20), and a Micron Q3 preview (4:55).

    Episode transcripts: seekingalpha.com/wsb

    Show links: 
    Nasdaq, S&P, Dow futures tick up after tech stocks recover
    Asia markets mixed on hotter-than-expected Australian CPI data; eyes on U.S. inflation data
    Exxon threatens to suspend French refinery if strike continues

    Sign up for our daily newsletter here and for full access to analyst ratings, stock quant scores, dividend grades, subscribe to Seeking Alpha Premium at seekingalpha.com/subscriptions.

    Pfizer working on new weight-loss drug mechanism

    Pfizer working on new weight-loss drug mechanism
    Weight loss drug candidate will differ from popular GLP-1s. (0:16) Tesla recalls thousands of Cybertrucks. (3:09) Hedge funds keep cashing in on tech. (3:55)

    Show Notes
    Airbus's stock falls more than 9% after cutting guidance
    U.S. consumer confidence pulls back in June, but range-bound for past two years

    Episode transcripts seekingalpha.com/wsb
    Sign up for our daily newsletter here and for full access to analyst ratings, stock quant scores, dividend grades, subscribe to Seeking Alpha Premium at seekingalpha.com/subscriptions.

    Boeing shifts to stock deal to acquire Spirit Aerosystems

    Boeing shifts to stock deal to acquire Spirit Aerosystems
    Boeing (BA) offers to buy Spirit Aero (SPR) for $35 a share mainly in stock - WSJ. (00:28) Novo Nordisk (NVO) to spend $4.1B to build new plant for obesity drugs in N.C. (01:12) Oracle (ORCL): TikTok (BDNCE) ban in U.S. would 'adversely' impact earnings. (02:04)

    Episode transcripts seekingalpha.com/wsb.

    Show links: 
    Biggest stock movers today: DJT, SEDG, EPAC and more
    Shein confidentially files paperwork for possible London IPO - reports
    Uber cutting out idle time for NYC drivers by enacting lock-out periods - report
    Google working on customizable chatbot product to rival Meta, Character. AI - report

    Sign up for our daily newsletter here and for full access to analyst ratings, stock quant scores, dividend grades, subscribe to Seeking Alpha Premium at seekingalpha.com/subscriptions.

    UAE gets ready to roll the dice on casinos

    UAE gets ready to roll the dice on casinos
    United Arab Emirates' Marjan Island could rival Macau. (0:16) What can Paolo Maldini tell us about soft landings? (1:49) Disney's 'Inside Out 2' on the way to $1 billion. (4:23)

    Show Notes
    Gap between growth and small-cap is huge, but don't call it a bubble
    Micron sees price target raised at Citi, Wolfe ahead of earnings
    CrowdStrike reaches S&P 500 Index five years after IPO

    Episode transcripts seekingalpha.com/wsb
    Sign up for our daily newsletter here and for full access to analyst ratings, stock quant scores, dividend grades, subscribe to Seeking Alpha Premium at seekingalpha.com/subscriptions.

    ByteDance reportedly teams with Broadcom on AI chip

    ByteDance reportedly teams with Broadcom on AI chip
    ByteDance (BDNCE) working with Broadcom (AVGO) on advanced AI chip - report. (00:25) Fast-fashion firm Shein may abandon London IPO - report. (01:16) Freight M&A: UPS sells Coyote Logistics to RXO. (02:23)

    Episode transcripts seekingalpha.com/wsb.

    Show links: 
    Biggest stock movers today: RXO, RMD, and more
    CDK Global works on fixing data breach that hit thousands of car dealers
    Microsoft has a 'hidden' $100B opportunity inside. And it's all about cybersecurity
    Gap between growth and small-cap is huge, but don't call it a bubble - Oppenheimer

    Sign up for our daily newsletter here and for full access to analyst ratings, stock quant scores, dividend grades, subscribe to Seeking Alpha Premium at seekingalpha.com/subscriptions.

    Inflation data and NIke earnings on the way

    Inflation data and NIke earnings on the way
    A cool core PCE would put the Fed on the spot to cut in September. (0:18) The Mag 7, the Terrible 3 and the Magnificent 1. (2:14) Nike guidance in focus with Adidas snapping at its heels. (3:58)

    Show Notes
    Stocks with the highest ROIC but not the highest valuation
    Apple and Meta have held talks about AI partnership
    GLP-1 drugs linked to reduced dementia risk: study
    Earnings Calendar

    Episode transcripts seekingalpha.com/wsb
    Sign up for our daily newsletter here and for full access to analyst ratings, stock quant scores, dividend grades, subscribe to Seeking Alpha Premium at seekingalpha.com/subscriptions.

    Qualcomm dips following reports of AI laptop struggles

    Qualcomm dips following reports of AI laptop struggles
    Qualcomm (QCOM) dips following reports of AI laptop struggles; other chip stocks drop. (00:26) Canada said to be eyeing tariffs on Chinese EVs, following lead of U.S. and EU. (01:19) WHO warns on fake versions of Novo Nordisk's (NVO) Ozempic. (02:20)

    Episode transcripts seekingalpha.com/wsb.

    Show links: Biggest stock movers: ASAN, SWBI, and more
    Unprofitable growth stocks with a path to profitability - GS
    Top 10 Info Tech stocks according to SA Quant Ratings
    SoftBank boss regrets Nvidia stake sale, calling it 'the fish that got away'

    Sign up for our daily newsletter here and for full access to analyst ratings, stock quant scores, dividend grades, subscribe to Seeking Alpha Premium at seekingalpha.com/subscriptions.

    Dell, Super Micro in on xAI supercomputer

    Dell, Super Micro in on xAI supercomputer
    Elon Musk says the duo will provide servers for the supercomputer. (0:16) Housing numbers slump. (2:09) UBS spies small-cap outperformance. (5:38)

    Show Notes
    Seeking Alpha Investing Summit insight
    Nvidia ahead in 'big tech race' to $4T as GPUs are tech's 'new gold or oil'
    Kroger rallies after topping Q1 estimates, backing full-year profit guidance

    Episode transcripts seekingalpha.com/wsb
    Sign up for our daily newsletter here and for full access to analyst ratings, stock quant scores, dividend grades, subscribe to Seeking Alpha Premium at seekingalpha.com/subscriptions.

    Switzerland cuts rates again as Fed holds steady

    Switzerland cuts rates again as Fed holds steady
    Policy divergence: Switzerland cuts interest rates for second time this year. (00:21) Former OpenAI chief scientist Ilya Sutskever unveils new AI company. (00:56)  Netflix House (NFLX) to open in Pennsylvania, Texas next year. (01:48)

    Episode transcripts seekingalpha.com/wsb.

    Show links: 
    Biggest stock movers today: NVDA, DJT, and more
    BlackRock sees no AI bubble and says AI winners will drive market returns for a while
    Accenture plans to buy Fibermind - a network services player in Italy
    U.S. homebuilder sentiment declines for the second month

    Sign up for our daily newsletter here and for full access to analyst ratings, stock quant scores, dividend grades, subscribe to Seeking Alpha Premium at seekingalpha.com/subscriptions.

    Softer retail sales, rate cuts and tech's top targets

    Softer retail sales, rate cuts and tech's top targets
    Nasdaq, S&P, Dow drift after retail sales come in softer than expected (0:35). 2 Fed rate cuts in 2024 and 6 in 2025? (1:47). Nvidia driving things; anxiety about 2nd half of the year (2:50). Apple price target raised; tech bull market 'is just starting.' (4:00). Crypto eventually going to be in every portfolio (7:20).

    Episode transcripts: seekingalpha.com/wsb

    Show links: 
    Nvidia rises after Rosenblatt sets Street High PT of $200
    Invesco sees two rate cuts this year while KPMG sees six in 2025; SA Summit
    Apple's price target raised at J.P. Morgan on AI boost to iPhones
    Tech bull market to last another 2–3 years
    Powell And The Fed Are More Hawkish Than You Think: Expect Economic Weakness Ahead





    Sign up for our daily newsletter here and for full access to analyst ratings, stock quant scores, dividend grades, subscribe to Seeking Alpha Premium at seekingalpha.com/subscriptions.

    Related Episodes

    Here comes Nvidia

    Here comes Nvidia
    Nvidia is due for the most important earnings report in years. (0:15) Walmart reports results ahead of stock split. (2:05) How do the biggest modern bubbles look today? (4:59)

    Show Notes
    Seeking Alpha Catalyst Watch
    Earnings Calendar

    Episode transcripts seekingalpha.com/wsb
    Sign up for our daily newsletter here and for full access to analyst ratings, stock quant scores, dividend grades, subscribe to Seeking Alpha Premium at seekingalpha.com/subscriptions.

    Fed holds rates, Powell shuts door on March cut

    Fed holds rates, Powell shuts door on March cut
    Stocks sink as Fed chief Jay Powell calls a March interest rate cut unlikely. (0:17) Boeing suspends 2024 guidance amid 737 problems. (4:23) Walmart switches gears to open new stores. (4:57)

    Show Notes
    Private sector adds 107K jobs in December, less than expected
    Seeking Alpha's Alpha Picks portfolio

    Episode transcripts seekingalpha.com/wsb
    Sign up for our daily newsletter here and for full access to analyst ratings, stock quant scores, dividend grades, subscribe to Seeking Alpha Premium at seekingalpha.com/subscriptions.

    Fed, jobs report ahead as Apple, Amazon report

    Fed, jobs report ahead as Apple, Amazon report
    Traders will be looking for any hints to the timing of rate cuts. (0:17) Apple and Amazon lead the earnings parade. (2:06) Elon Musk makes surprise visit to China. (4:12)

    Show Notes
    SA Analyst Roundtable: When will the Fed cut rates?
    Earnings Calendar
    Baird says short interest increased in April in the fashion and wellness industries

    Episode transcripts seekingalpha.com/wsb
    Sign up for our daily newsletter here and for full access to analyst ratings, stock quant scores, dividend grades, subscribe to Seeking Alpha Premium at seekingalpha.com/subscriptions.

    Goldman Sachs posts strong numbers

    Goldman Sachs posts strong numbers
    Goldman's global banking and markets business rebounds in latest quarter. (0:15) Retail sales in March trounce expectations. (2:03) Tesla confirms it will lay off 10%. (4:01)

    Show Notes
    Small and midcap pair trades for every sector - Oppenheimer

    Episode transcripts seekingalpha.com/wsb
    Sign up for our daily newsletter here and for full access to analyst ratings, stock quant scores, dividend grades, subscribe to Seeking Alpha Premium at seekingalpha.com/subscriptions.

    Apple Vision Pro potential 'game changer'

    Apple Vision Pro potential 'game changer'
    The Vision Pro is showing customer intrigue not seen in many years. (0:16) Service inflation has yields climbing after Powell remarks. (1:55) How do the Magnificent 7 stack up against the Tech Bubble 5? (5:02)

    Show Notes
    Hertz Global hits the brakes on EV plans with Polestar Automotive
    McDonald's falls short of Q4 comparable sales expectations

    Episode transcripts seekingalpha.com/wsb
    Sign up for our daily newsletter here and for full access to analyst ratings, stock quant scores, dividend grades, subscribe to Seeking Alpha Premium at seekingalpha.com/subscriptions.