Perspectives From Latin America on Advances in HIV PrEP

In this episode, Robert Wong, MD, MS, and a patient discuss opportunities to optimize care for people living with hepatitis B virus (HBV), including:

• Opportunities to improve patient education, including education for expectant mothers with HBV
• Potential cultural considerations that may result in delayed HBV diagnosis and care 
• Stigma reduction with universal HBV screening and vaccination
• Strategies to improve patient education (eg, online resources, advocacy groups, use of layman’s terms and diagrams, repetition)

Presenter: 

Robert Wong, MD, MS 
Clinical Associate Professor 
Division of Gastroenterology and Hepatology
Stanford University School of Medicine
Palo Alto, California

Content based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program: 
https://bit.ly/49TuZ8U

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

Listen to Roger Bedimo, MD, MS, FACP, discuss considerations for older people living with HIV, including:

• Polypharmacy and deprescribing
• The risk of cardiovascular events with various ART regimens
• Approaches for managing weight gain

Presenter:

Roger Bedimo, MD, MS, FACP
Professor of Medicine
Interim Director, Office of Global Health
UT Southwestern Medical Center
Chief, Infectious Diseases Section
VA North Texas Health Care System
Dallas, Texas

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

To download the slides: 
 https://bit.ly/49zrnZs

To view the full online program:
https://bit.ly/49x0W6D

In this episode, Dr. Bedimo discusses best practices for individualized care in transgender women living with HIV, including:

• Providing services in a gender-affirmative care model
• Proactive counseling on drug-drug interactions with gender-affirming hormone therapy
• Strategies to reduce adverse events

Presenter:

Roger Bedimo, MD, MS, FACP
Professor of Medicine
Interim Director, Office of Global Health
UT Southwestern Medical Center
Chief, Infectious Diseases Section
VA North Texas Health Care System
Dallas, Texas

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

To download the slides: 
https://bit.ly/49zrnZs

To view the full online program:
https://bit.ly/49x0W6D

In this episode, Renslow Sherer, MD, and Trinh P. Vu, PharmD, BCIDP, discuss how to optimize the use of COVID-19 antivirals and how to navigate drug-drug interactions between COVID-19 treatments and a patient’s home medications. Their discussion includes:

• Current COVID-19 landscape
• COVID-19 testing and vaccination recommendations
• Treatment guidelines and antiviral options for nonhospitalized adults with COVID-19
• Resources for assessing and managing COVID-19 antiviral-related drug-drug interactions
• Answers to learners’ most pressing questions

Presenters:

Renslow Sherer, MD
Professor of Medicine
Section of Infectious Diseases and Global Health
University of Chicago
Chicago, Illinois

Trinh P. Vu, PharmD, BCIDP
Clinical Pharmacy Specialist in Infectious Diseases
Department of Pharmacy
Emory University Hospital Midtown
Atlanta, Georgia

Slideset: https://bit.ly/4c6kwbJ

Downloadable resource:
https://bit.ly/49rofP6

Full program: 
https://bit.ly/3P16TR8

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts or Spotify.

In this episode, Nancy Reau, MD, discusses new data on hepatitis B virus presented at AASLD 2023, including:

• Current therapies
  • Studies 108 and 110: Factors Linked With Lack of Virologic Suppression After 8 Yr of TAF or TDF
  • Kaiser Permanente Northern California: HCC or Death With TDF vs ETV for Chronic Hepatitis B
  • Early vs Late Postpartum Cessation of TDF Initiated for Prevention of Vertical HBV Transmission
• Investigational functional cure strategies
  • B-Together: Sequential Bepirovirsen and PegIFN Added to NA Therapy for Chronic HBV Infection
  • MARCH Part B: VIR-3434 ± VIR-2218 ± PegIFN Added to NA Therapy for Chronic HBV Infection
  • REEF-IT: JNJ-3989 + NA ± JNJ-6379 With PegIFN Add-on Consolidation in Patients With HBeAg-Positive CHB
  • HBV003: VTP-300 + Nivolumab Added to NA Therapy for Chronic HBV Infection
  • CVP-NASVAC: Nasally Administered Therapeutic Vaccine for Chronic HBV Infection

Presenter:
Nancy Reau, MD
Professor of Medicine
Richard B. Capps Chair of Hepatology
Chief, Section of Hepatology
Associate Director, Solid Organ Transplantation
Rush University Medical Center 
Chicago, Illinois

Link to full program: 
https://bit.ly/47XJlU4

In this episode, LaRon E. Nelson, PhD, RN, FNP, FNAP, FNYAM, FAAN, discusses the role that healthcare professionals (HCPs) may be playing in their patients’ pre-exposure prophylaxis (PrEP) persistence and strategies to modify their approach to encourage persistence, from Clinical Care Options (CCO), including:

• Racial disparities in the PrEP care continuum
• Consideration that PrEP persistence may be less about relationship to the drug than the environment
• Examples of HCP implicit bias regarding PrEP responsibility based on racism and sexual prejudice
• Impact of HCP implicit bias on PrEP persistence
• Impact of racism on clinical cognition
• The demonstrated effects of stereotype threat and the potential healthcare implications
• Ways to improve clinical conversations about PrEP
• Providing person-centered care to encourage PrEP persistence using the Client‑Centered Care Coordination (C4™) Model

Faculty

LaRon E. Nelson, PhD, RN, FNP, FNAP, FNYAM, FAAN
Independence Foundation Professor
School of Nursing
Yale University
New Haven, Connecticut

Follow along with the slides: 
https://bit.ly/497cahK

Link to full program:
https://bit.ly/3ZlICsL

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease podcast on Apple Podcasts, Google Podcasts, or Spotify.

In this episode, Nancy Reau, MD, and her patient discuss opportunities to optimize care for people living with hepatitis B virus and hepatitis delta virus, including:

• The importance of patient education along the care continuum
• Ensuring smooth transitions of care and communication between medical teams
• Screening hepatitis delta in persons with chronic hepatitis B
• Managing hepatitis delta, including considerations for clinical trials
• Promoting patient advocacy

Presenter: 

Nancy Reau, MD
Professor of Medicine 
Chief, Section of Hepatology
Associate Director, Solid Organ Transplantation
Richard B. Capps Chair of Hepatology
Rush University Medical Center
Chicago, Illinois

Content based on an online CME program supported by an independent educational grant from Gilead Sciences, Inc.

Link to full program: bit.ly/3SrMuGO

Get access to all of our new podcasts by subscribing to the CCO Infectious Disease Podcast on Apple Podcasts, Google Podcasts, or Spotify.

In this episode, David Saunders discusses the value of nonstigmatizing discussions between people using HIV pre-exposure prophylaxis (PrEP) and healthcare professionals, including: 

• Encouraging accountability to individualize adherence strategies and improve persistence to PrEP
• Reducing stigma, discrimination, and prejudice in healthcare settings to foster PrEP persistence

Faculty: 

David Saunders
PrEP User and Advocate

Link to full program:
https://bit.ly/3ZlICsL

To automatically get new episodes as soon as they launch, subscribe to the CCO Infectious Disease podcast.

In this episode, Sarah M. Wood, MD, MS, discusses data and recommendations for long-acting pre-exposure prophylaxis (PrEP) as a strategy to support PrEP persistence and engagement for adolescents, including: 

• The PrEP care continuum for adolescents
• System barriers to PrEP coverage and privacy concerns for adolescents
• The benefits and challenges of same-day PrEP initiation and real-world data to support it
• Interventions to support PrEP persistence
• PrEP options for different populations and the data to support the efficacy of long-acting cabotegravir (CAB) PrEP from HPTN 083 and HPTN 084
• Data and recommendations for a CAB PrEP oral lead-in
• Data from HPTN 083 showing no interaction between feminizing hormone therapy and long-acting CAB PrEP
• Project LifeSkills: a culturally specific, empowerment-based, group-delivered behavioral HIV prevention intervention for young transgender women

Faculty

Sarah M. Wood, MD, MS
Assistant Professor of Pediatrics 
Division of Adolescent Medicine
Perelman School of Medicine
University of Pennsylvania 
Children’s Hospital of Philadelphia
Philadelphia, Pennsylvania

Follow along with the slides: 
https://bit.ly/3Ha9Kmt

Link to full program: 
https://bit.ly/3ZlICsL

To automatically get new episodes as soon as they launch, subscribe to the CCO Infectious Disease podcast show.

In this episode, Angela Branche, MD, discusses RSV vaccines in older adults, including: 

• Current Advisory Committee on Immunization Practices recommendations
• Risk factors associated with severe RSV disease, including RSV-related hospitalizations
• Approach to stratifying risk factors (eg, age, comorbidities) in determining which adults may benefit from the RSV vaccine 
• Ongoing research on RSV vaccines in younger adults (eg, aged 40s and 50s years) with chronic comorbidities 
• Health disparities related to RSV vaccines
• Considerations for a risk-based approach, rather than age alone, to determine vaccine candidacy 

Faculty: 

Angela Branche, MD
Associate Professor of Medicine
Division of Infectious Diseases
Department of Medicine
University of Rochester
Rochester, New York

Link to full program: 
https://bit.ly/3nb25xe

Link to downloadable slides: 
https://bit.ly/3TsXym5