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    Tools for Managing Stress & Anxiety

    enMarch 08, 2021
    What is the relationship between stress and emotions?
    How can controlling breath affect stress response?
    What physiological mechanisms help in managing stress?
    Why is mindfulness described as a vague concept?
    What studies are exploring stress modulation techniques?

    Podcast Summary

    • Understanding Stress, Emotions, and the Importance of ControlStress is a natural response that can enhance our immune system, but it can also lead to negative emotions. By understanding how stress affects us and learning objective tools to control our emotions, we can better manage our internal experience and live more fulfilling lives.

      Stress lies at the heart of our internal experience not matching our external experiences, creating emotions. Emotions have a strong physiological component involving the brain and body's communication. The nervous system, which controls the body and brain, has a concrete influence on each other. Stress is not always bad, and it can enhance the immune system. Mindfulness is a vague concept, and today we're discussing objective tools to control emotions and lean into life better. This gives us greater power and control over our inner real estate, allowing us to control our emotions when appropriate. It's important to understand what stress is and that it's not just an ancient leftover from times when we were being attacked by predators.

    • Understanding and Controlling Your Stress ResponseStress is inevitable, but we can control our response to it. Our stress response is initiated by a chain of neurons and is generic regardless of the type of stressor. By understanding the biology behind stress, we can use tools like meditation and breathwork to de-stress in real-time.

      Stress is a universal experience for all species, and it is not something we can completely eliminate from our lives. However, we can control our stress response with hardwired biological mechanisms that exist in us, allowing us to de-stress in real time. Stressors can be physical or emotional and our response to them is generic. Our stress response is initiated by a chain of neurons called sympathetic chain ganglia, which become activated in response to stress. Understanding the underlying mechanisms of stress and our response to it can help us better incorporate stress-reducing tools like meditation and breathwork, and to modify them as our circumstances change. Our ability to control our stress is a powerful tool, and through the right tools and understanding, we can learn to breakthrough it in real-time.

    • The two-pronged reaction of stress and practical solutionsDeep breathing or meditation can reduce stress quickly and understanding the stress response is crucial for effective stress management. Telling oneself or others to calm down does not work.

      The stress response is a two-pronged reaction in which the body activates certain systems while shutting down others. The result is an agitation that is designed to make you move or speak. To reduce or eliminate stress quickly in real-time, tools that have a direct line to the autonomic nervous system, such as deep breathing or meditation, are recommended. Telling oneself or others to calm down does not work and can even exacerbate stress. Understanding the stress response and learning how to work with its agitation is crucial for stress management.

    • The Power of Physiological Sigh for Stress Management.By controlling your breathing with physiological sigh, you can directly affect your heart rate and reduce stress response. Inhale longer or more vigorously to speed up your heart rate, exhale longer or more vigorously to slow it down.

      The parasympathetic nervous system has levers that allow you to push back on stress in real-time and feel relaxed quickly. One effective technique is physiological sigh, which involves controlling your breathing to directly affect your heart rate. Inhalations and exhalations affect the size of your heart and the speed of blood flow, which can elicit different responses from the sinoatrial node and impact heart rate. By inhaling longer or more vigorously than exhaling, you can speed up your heart rate. Conversely, if you want to slow down your heart rate and reduce stress response, exhale longer or more vigorously than inhaling. Understanding these mechanisms of physiological si can enable you to conveniently and self-directedly manage stress in your daily life.

    • The Physiology of Stress Control Through Breathing TechniquesExhales are the quickest way to calm down and the physiological p sigh, a double inhale and long exhale, helps to eliminate stress response in real-time. You can voluntarily control your diaphragm to double or triple inhales/exhales, modulating emotionality and stress response.

      Controlling stress can be achieved through the relationship between the body, the meaning, the diaphragm, heart and brain. Exhales play a vital role in calming down quickly and require no learning. The physiological p sigh, a double inhale and long exhale combination, reinflates little sacks of lungs and rids the body and bloodstream of carbon dioxide, relaxing you immediately. You can control your diaphragm voluntarily to double or even triple up your inhales or exhales. Physiological p sigh, the fastest hardwired way to eliminate the stress response in real-time, can modulate emotionality and stress response. Huberman and David Spiegel's ongoing studies explore the effective modulation of stress response through various breathing patterns.

    • The Power of Physiological Sigh BreathingTake control of your stress levels in real-time by using the physiological sigh technique. Double inhale through your nose and exhale through your mouth. Repeat one to three times for fast relief from heightened alertness.

      The physiological sigh, which involves double inhale through the nose and exhale through the mouth, is a powerful tool for controlling stress levels in real-time situations. When we are stressed, it is difficult to control our mind with our mind, but using physiological breathing techniques can quickly bring our levels of autonomic activation down. This technique should be done one to three times, bringing fast relief to a heightened state of alertness. It is important to note that the heart rate may take time to come down to baseline, so repeat the physiological sigh as necessary. This tool can also improve our brain and mind's availability to control the stress response and react to it. Additionally, exhale emphasized breathing can be used to induce sleep and relaxation, making it a useful tool for those with trouble sleeping or relaxing.

    • The Connection Between Breathing, Stress, and Our HealthOur breathing and level of stress affect our emotional and physical health. By activating our para facial nucleus through the physiological sigh, we can improve our speaking and relaxation. Understanding different types of stress can help us better manage our well-being.

      Breathing and stress have a profound impact on our emotions and functioning. The para facial nucleus in the brain is responsible for helping us breathe while speaking and relaxing our jaw. By using the physiological sigh, we can activate this neural circuitry and speak more clearly. Stress can be short-term, medium-term, or long-term, and each type of stress has different effects on our bodies. While chronic stress is harmful, acute stress can boost our immune system by combatting bacterial and viral infections. It's important to understand the boundaries and guidelines around stress to better manage our emotional and physical health.

    • Short-term stress can boost immune function but should be used with cautionControlled short-term stress can prime the immune system to fight infections, but it's important to balance stress levels and avoid overuse of stress-inducing techniques like hyperventilation or exposure to cold.

      Short-term stress and the release of adrenaline, specifically through deliberate hyperventilation or exposure to cold, can be beneficial in combating infections. Adrenaline released during the stress response primes the immune system to fight against invaders like bacteria and viruses. This was demonstrated in a study where participants who did deliberate hyperventilation were better able to combat a bacterial wall that mimicked infection. However, it is important to note that short-term stress narrows our focus and may not be ideal for seeing the big picture. It is also important to control stress thresholds and not overuse this tool. This breathing technique is called whim Hoff breathing and it involves rapid deliberate breathing for 15-25 cycles. Overall, short-term stress and adrenaline release should not be overlooked in the context of fighting infections.

    • How Short-Term Stress Can Be Beneficial and How to Use it WiselyShort-term stress can be beneficial for healing and focus, but chronic stress can harm the immune system and overall health. Learn to turn off your stress response and use stress wisely, while avoiding risky activities like hyper oxygenated breathing near water.

      Activating your stress system through short-term stress can be beneficial for combating infection and healing wounds. Deliberately activating your stress response through methods like hyper oxygenated breathing can be beneficial, but it is important to know when to press the break and turn it off. Chronic stress can have negative effects on the immune system and overall health. Therefore, it is crucial to learn how to turn off your stress response and achieve good sleep. Short-term stress is not always intense and can help with tasks like focusing on a deadline. It is important to remember that stress acts like a powerful neutropic or smart drug and can be used to your advantage but should be used responsibly and with caution depending on one's health conditions. Lastly, it is crucial to avoid certain stress-inducing activities such as deliberate hyper oxygenated breathing near water to prevent any health risks

    • Building Stress Resilience with Simple ToolsTo manage medium term stress, try activities that increase adrenaline such as cold showers or sprinting, and then mentally calm yourself. This increases stress capacity and makes stress more manageable.

      Managing medium term stress involves raising our stress threshold through simple tools such as placing ourselves in situations where adrenaline is increased and then calming ourselves mentally. This helps things that once felt unmanageable feel manageable. Such tools include cold showers, cyclic oxygenation breathing, sprinting, or biking. Dissociating mind and body in a healthy way is important. To do this, we need to relax the mind while the body is very activated. Physiological responses help calm the mind when it's stressed. By doing this, it increases our stress capacity and makes medium term stress more manageable.

    • Dilating Your Gaze to Manage Stress and Improve SleepWidening your view from tunnel vision to panoramic vision can calm your mind and release stress response in the brainstem. This can be trained over time to make stress more manageable and improve sleep through regulating heart rate with breathing.

      Dilating your gaze can help in managing stress. By deliberately widening your view from tunnel vision to panoramic vision, you can calm your mind while your body stays in high alertness, high reactivity mode, high output. It creates a calming effect on the mind because it releases a particular circuit in the brainstem that's associated with stress response. Training yourself to be calm when your body is activated can make stress more manageable in the medium term. Long-term stress is bad, and you want to be able to fall asleep at night, stay asleep for most of the night, and go back to sleep if you wake up. Breathing can modulate heart rate through the loop that includes the brain and the parasympathetic nervous system, and this is the basis of H R V heart rate variability.

    • The Importance of Social Connection in Managing Chronic StressExercise, sleep and stress management tools are important for managing long-term stress, but social connection is crucial. It activates our neuromodulation systems and mitigates the negative effects of stress, leading to feelings of wellbeing.

      Chronic stress is bad for our health and can lead to heart disease. To manage long-term stress, engaging in regular exercise, getting good sleep, and using real-time tools to manage stress response are essential. However, the best mechanism to reduce long-term stress is social connection. Humans are social creatures, and we need to stay connected to one another. Social connection can mitigate the long-term effects of stress by activating neuromodulation systems like serotonin and blocking certain harmful elements like tacky kinan. While oxytocin is not associated with the release of social connection, serotonin generally gives us feelings of wellbeing and makes us feel like we have enough in our immediate environment.

    • The Power of Social Connection and Delight in Mitigating Chronic StressMaintaining social connections can suppress harmful molecules and promote positive functions in our brain and body. Paying attention to feelings of comfort and delight can have positive effects on our immune system and neural repair.

      Social connection and finding delight in things can mitigate the negative effects of chronic stress and improve various aspects of our life. It's important to invest time and effort in maintaining connections, whether it's with humans, animals or even inanimate objects. Chronic social isolation leads to the secretion of tachykinin, a harmful molecule that makes us more fearful, paranoid and impairs our immune system. Suppressing tachykinin is crucial as it promotes good functions of our brain and body and prevents bad ones like irritability and fear. Paying attention to feelings of comfort, trust, bliss and delight can help recognize the release of serotonin in the brain which has positive effects on the immune system and neural repair. Social connections are powerful and worth the investment of time and flexibility.

    • The Power of Gratitude and Stress ManagementPracticing gratitude and implementing stress-management techniques, such as social connections, a healthy diet, exercise, and quality sleep, can positively impact overall wellbeing. Non-prescription compounds like ashwagandha and theanine can help, but be cautious with high-dose melatonin supplementation.

      Practicing gratitude by recognizing and writing down small things you're thankful for can have a positive effect on the serotonin system, which can help reduce long-term stress. It's important to also focus on social connections, finding the right diet and exercise schedule, and getting quality sleep. There are non-prescription compounds like ashwagandha, theanine, and melatonin that can help modulate the stress system, but it's important to be cautious with supplementing melatonin at high doses as it can have negative effects on reproductive hormones and the adrenals. While there's no such thing as adrenal burnout, taking melatonin at high levels for too long can cause a pseudo adrenal insufficiency syndrome. Overall, practicing gratitude and finding ways to modulate the stress system can greatly benefit overall wellbeing.

    • The Benefits of Theanine and Ashwagandha for Sleep, Stress, and AnxietyTheanine and Ashwagandha can be helpful in reducing sleep issues, chronic stress, and anxiety by increasing GABA and reducing cortisol levels respectively. They should only be used during times of chronic stress and in appropriate dosages. Avoid tourine found in energy drinks.

      Supplementing with theanine and Ashwagandha can help alleviate sleep issues, chronic stress, and anxiety. Theanine can improve sleep quality and reduce stress by increasing GABA, an inhibitory neurotransmitter in the brain. It can also help reduce anxiety related to task completion. Ashwagandha, on the other hand, can reduce cortisol, which is associated with the negative effects of chronic stress. It can also reduce fatigue, cognitive impairment, and depression. Both supplements should be taken during times of chronic stress and not on a regular basis. Examine.com is a great resource to find dosages and the human effect matrix. Tourine, found in energy drinks, may have negative effects on the microvasculature and isn't recommended for everyone.

    • Controlling Stress through Physiological and Neuroscience Perspective.Matching your internal state with the demands placed upon you is crucial for interpreting emotions. Tools like proper diet, exercise, and sleep can help control stress. Understand your emotions better through a physiological and neuroscience perspective.

      Matching your internal state with the demands placed upon you is crucial for interpreting emotions. When our internal state of stress or calm matches the demands, we tend to interpret them as good, and when it's mismatched, we tend to interpret them as bad. Understanding stress and controlling it can help us stay in a better position to handle demands. Tools like respiration, dilation of gaze, social connection, and proper diet, exercise, and sleep can help control stress. Emotions are context-dependent, and having a physiological and neuroscience perspective helps understand it better. Stress will happen, but our ability to modulate and control it in real-time using tools can help take control over it.

    • Modulating Stress Response for Optimal PerformanceLearning to modulate stress can improve our ability to process information and react more effectively. Tools anchored to our body, brain, eyes, and diaphragm can help control our internal levels of alertness or calmness, improving sleep, work, and social connection.

      Learning to modulate your stress response can help you hear information better and react to things in a more effective way. This can be achieved in real time by using tools that are anchored to the neuronal systems in our body, brain, eyes, and diaphragm. Poor rest, overwork, and feeling like the world is bearing down on us can make us grumpy, anxious, or depressed. Therefore, it's important to have tools that can help us modulate our stress response. Stress isn't necessarily evil, but it's powerful and useful in certain contexts and problematic in other contexts. What's in our control is how we react to events in the world. By using tools to control our internal levels of alertness or calmness, we can lean more effectively into life, including sleep, social connection, and work.

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    Dr. Layne Norton: Tools for Nutrition & Fitness
    In this episode, my guest is Dr. Layne Norton, Ph.D., one of the world’s top experts in nutrition and training for physical fitness. We discuss how to evaluate scientific evidence and the validity of different practices aimed at achieving fat loss, muscle strength and hypertrophy, microbiome health, vitality, and longevity. We explore many hotly debated topics, including fasting, seed oils, saturated fats, sugar, red meat, artificial/low-calorie sweeteners, and GLP-1 agonists (e.g., Ozempic). Additionally, we delve into the timing of protein and carbohydrate intake relative to fasting and exercise, fat loss and sleep, and the benefits of dietary protein and fiber on overall health. We also discuss how to accelerate hypertrophy and fat loss, improve strength, whether we need to train to “failure,” how to enhance exercise recovery, and how to manage pain. We cover training before versus after age 50, whether metabolism changes with age, and the connection between muscle health and longevity. We also address why certain behaviors and supplements might work for some people but not others. Listeners to this episode will benefit greatly from Layne’s science-based expertise on a wide range of topics, including health, nutrition, and fitness. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Mateina: https://drinkmateina.com/huberman Eight Sleep: https://www.eightsleep.com/huberman Maui Nui: https://mauinuivenison.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Dr. Layne Norton 00:01:49 Sponsors: Mateina, Eight Sleep, Maui Nui 00:06:39 Science-Based Evidence, Mechanism vs. Outcome 00:14:31 Meta-analysis, Methods, Evidence Quality 00:22:45 Evidence Hierarchy, Randomized Controlled Trials, Cohort Data 00:33:53 Sponsor: AG1 00:35:05 “Don’t Turn Your Brain Off”; Protein Synthesis 00:42:01 Protein Synthesis, Refractory Response; Resistance Training   00:46:05 Protein Intake, Intermittent Fasting & Training 00:54:52 Tool: Total Protein Intake, Distribution & Protein Synthesis 01:00:25 Muscle Quality, Protein Remodeling, Muscle Growth 01:05:34 Sponsor: LMNT 01:06:46 Early vs. Late Time-Restricted Eating; Fasting Blood Glucose & HbA1c 01:10:30 Carbohydrate Timing, Individual Response, Placebo; Tool: Tracking Diet 01:19:50 “The Norton Method”; Tool: Consistency 01:25:16 Resistance & Cardiovascular Training; Competition; Immune System & Rest 01:33:50 Mind & Body Effects, Stress; Belief Effects 01:41:30 Training to Failure, Reps in Reserve, Hypertrophy & Strength Training 01:50:24 Fatigue & Training to Failure, Speed, Strength Training 01:59:06 Tool: Training After 50, Consistency 02:09:12 Fat Cells, Diabetes, Exercise 02:16:50 Metabolism & Age-Related Changes?, Appetite 02:23:17 Ozempic, Mounjaro, GLP-1 Agonists, Lean Mass, “Food Noise” 02:33:42 GLP-1 Agonists, Judgement & Obesity 02:40:19 Sugar, Excess Calories, Body Weight 02:49:16 Satiety, Sugar & Calorie Budget 02:54:56 Tool: Individualization, Context & Diet Psychology 02:57:22 Seed Oils, Butter, Olive Oil 03:06:56 Red Meat, Carcinogenic?; Simple Diet; Fiber Benefits 03:13:43 Saturated Fat, Cholesterol; Seed Oils 03:18:41 Artificial & Low-Calorie Sweeteners, Insulin, Appetite 03:29:06 Artificial & Low-Calorie Sweeteners, Gut Microbiome; Cancer 03:37:58 Tools: Training Recovery, Glycogen Replenishment; Stress & Activity 03:45:56 Collagen Supplementation, Skin & Nails, Whey Protein 03:57:00 Evidence-Based Approach 04:01:41 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures
    Huberman Lab
    enAugust 12, 2024

    Dr. Martha Beck: Access Your Best Self With Mind-Body Practices, Belief Testing & Imagination

    Dr. Martha Beck: Access Your Best Self With Mind-Body Practices, Belief Testing & Imagination
    In this episode, my guest is Dr. Martha Beck, Ph.D., a Harvard-trained sociologist, bestselling author, and one of the world’s foremost experts on personal exploration and development.  Dr. Beck shares specific frameworks and practices to tap into your unique and deepest desires, core truths, and best life direction—all elements that comprise your authentic self. She also explains how to align your work and relationships of all kinds with your true self and how to embrace the discomfort and process of leaving unhealthy relationships. We discuss how to deal with negative thoughts and emotions, grapple with societal norms, and improve body awareness to gauge your inner truth. We also discuss codependency and self-abandonment - and how to exit and recover from these experiences.  By the end of the episode, you will have learned numerous practical tools to access your best self and live a richly fulfilling life.  Access the full show notes for this episode at hubermanlab.com. Dr. Beck's Wayfinder Life Coach Training: https://marthabeck.com/life-coach-training Thank you to our sponsors AG1: https://drinkag1.com/huberman BetterHelp: https://betterhelp.com/huberman Helix Sleep: https://helixsleep.com/huberman LMNT: https://drinklmnt.com/huberman Waking Up: https://wakingup.com/huberman Timestamps 00:00:00 Dr. Martha Beck 00:01:34 Sponsors: BetterHelp, Helix Sleep & LMNT 00:05:34 Tool: Perfect Day Exercise 00:15:31 “Clear Eyed”, Male vs. Female 00:23:31 Family & Work; Directed Attention & Miracles 00:30:21 Sponsor: AG1 00:32:10 Unease, Restlessness & Guilt; Life Worth, Fear 00:37:22 Accessing the Subconscious; Compassionate Witness Self 00:46:16 Finding Self, Suffering, Anxiety; Tool: “KIST”, Self-Parenting 00:54:01 Self, Radiance, Death; Awakening 00:59:14 Suffering & Compassionate Attention 01:02:10 Challenging Internal Thoughts, Understanding Truth, Body & Mind; 01:08:44 Sponsor: Waking Up 01:10:20 Western Society & Pressure 01:18:30 Tool: Sensing Truth in Body; Meditation, “Stopping the World” 01:25:02 Energy, Magnetoreception, Pet’s Death 01:33:49 Lying to Ourselves, Addiction 01:38:18 Tool: “Integrity Cleanse”, Lies; The Light 01:47:32 Relationship with Loss; Love, Self-Abandonment & Codependency 01:55:10 Romantic Relationships; Jobs & Family 02:02:06 Hurting Others, Relationship Imbalance 02:06:55 Tool: True Empathy 02:11:26 “Happiness is an Inside Job”, Codependency 02:18:58 Live Your Joy, Western Society 02:24:41 Relationships, Love & Integrity, “Feeling Good By Looking Weird” 02:30:42 “I Like It!”, Punk Rock Music, Love 02:34:24 Honesty & Essential Self; Helping People & Healers 02:42:12 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures
    Huberman Lab
    enAugust 05, 2024

    AMA #18: Cold Therapy Advice, Skin Health Tips, Motivation, Learning Strategies & More

    AMA #18: Cold Therapy Advice, Skin Health Tips, Motivation, Learning Strategies & More
    Welcome to a special edition of the 18th Ask Me Anything (AMA) episode, part of Huberman Lab Premium. This episode is a recording of the live stream AMA, exclusive to our Premium members. We've decided to make the full-length version available to everyone, including non-members of Huberman Lab Premium. Huberman Lab Premium was launched for two main reasons. First, it was launched in order to raise support for the main Huberman Lab podcast — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation and other donors. If you're not yet a member but enjoyed this full-length livestream AMA, we invite you to join Huberman Lab Premium. By subscribing, you'll gain access to exclusive benefits including our regular monthly full-length AMA episodes, AMA transcripts, podcast episode transcripts, early access to live events and more. Additionally, a significant portion of your membership proceeds contributes to advancing human scientific research. You can learn more about the research we were able to support in our Annual Letter 2023. If you're a Huberman Lab Premium member, you can access the transcript for this AMA episode here. Timestamps 00:00 Introduction & Announcements 00:15 Supporting Mental & Physical Health Research 01:56 Exciting New Research Initiatives 03:39 Skin Health & Appearance 14:46 Cold Therapy Benefits & Guidelines 21:18 Self-Motivation Strategies 27:05 Understanding REM Sleep 28:45 Morning Routine: Exercise & Cold Exposure 29:17 The Importance of REM Sleep 29:49 Non-Sleep Deep Rest (NSDR) Protocols 31:27 REM Sleep Rebound & Compensation 32:55 Impactful School Strategies for Learning 34:19 Meditation & Micro Gaps in Learning 39:13 Physical Activity & Learning 41:01 Exploring Shilajit & Testosterone 47:51 Writing Process & Overcoming Obstacles 51:32 Addiction & Recovery Resources 53:47 Closing Remarks & Gratitude Disclaimer & Disclosures
    Huberman Lab
    enAugust 02, 2024

    Dr. Peter Attia: Supplements for Longevity & Their Efficacy

    Dr. Peter Attia: Supplements for Longevity & Their Efficacy
    In this episode, my guest is Dr. Peter Attia, M.D., a Stanford and Johns Hopkins School of Medicine-trained physician expert in improving human healthspan and lifespan. Dr. Attia is also the host of The Drive podcast and author of the best-selling book Outlive.  We discuss the NAD pathway in human cells and its possible links to aging and health. We evaluate how supplementation can augment molecules in the NAD pathway; we compare NAD, NMN, and NR, different routes of administration, their safety, and bioavailability. Then, we discuss the broader research and clinical literature on longevity to decide if supplementation with NAD, NR, NMN, rapamycin, or resveratrol can indeed extend lifespan.  Finally, we each describe our supplement regimens and compare the role of supplementation to behaviors such as sleep, nutrition, and exercise for longevity. We also discuss whether tests of biological age are true indicators of aging and whether normal radiation levels increase cancer risk.  Listeners of this episode will learn if supplements purported to improve lifespan show any efficacy and the behaviors and other factors that can prevent disease and extend lifespan. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/huberman Levels: https://levels.link/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps 00:00:00 Dr. Peter Attia, NAD Pathway 00:02:31 Sponsors: LMNT, Levels & Eight Sleep 00:06:38 Categories of Longevity Approaches 00:17:22 Peter’s Supplements; Rapamycin & Research Data 00:25:01 NAD Pathway: Energy & DNA Repair; Knock-Out & Knock-In, Klotho 00:30:35 Sponsor: AG1 00:32:25 Yeast, Sirtuins, Caloric Restriction & Lifespan 00:38:56 Sirtuins, Transgenic Mice, Gender & Lifespan 00:43:42 DNA Repair, Sirtuins, Cancer; Resveratrol 00:53:31 Perform with Dr. Andy Galpin Podcast 00:54:18 NAD & NADH, Reactive Oxygen Species (ROS), Mitochondrial Health 01:02:17 NAD vs NR vs NMN Supplementation; IV & Oral Routes 01:11:33 NR vs. NMN, Doses, Side Effects; Interventions Testing Program 01:17:43 Fatty Liver Disease & NR; NMN & Glucose; Clinical Significance 01:25:17 Safety & FDA, NMN & NR Supplementation; Skin Cancer Benefits 01:30:38 Longevity, NR & NMN Supplementation, Inflammation 01:41:00 Rapamycin & Immune Function 01:44:37 Biological Aging Tests, Chronologic & Biologic Age; Vigor  01:55:24 Radiation & Cancer Risk 01:58:12 Tool: Self-Care in 50s-70s & Aging; Energy Decline 02:07:12 Tool: Exercise Timing & Energy Levels 02:11:22 Peter’s Supplements 02:18:46 Andrew’s Supplements 02:24:34 Tool: Supplement Use vs. Critical Behaviors; Titanic Analogy  02:26:52 NAD Pathway Supplementation for Longevity? 02:28:52 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Social Media, Neural Network Newsletter Disclaimer
    Huberman Lab
    enJuly 29, 2024

    Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

    Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity
    In this episode, my guest is Dr. Stacy Sims, Ph.D., an exercise physiologist, nutrition scientist, and expert in female-specific nutrition and training for health, performance, and longevity. We discuss which exercise and nutrition protocols are ideal for women based on their age and particular goals. We discuss whether women should train fasted, when and what to eat pre- and post-training, and how the menstrual cycle impacts training and nutrition needs. We also explain how to use a combination of resistance, high-intensity, and sprint interval training to effectively improve body composition, hormones, and cardiometabolic health, offset cognitive decline, and promote longevity.  We also discuss supplements and caffeine, the unique sleep needs of women based on age, whether women should use deliberate cold exposure, and how saunas can improve symptoms of hot flashes and benefit athletic performance. Dr. Sims challenges common misconceptions about women’s health and fitness and explains why certain types of cardio, caloric restriction, and low-protein diets can be harmful to women’s metabolic health. Listeners will learn a wealth of actionable information on how to improve their training and nutrition to enhance their health and how to age with greater ability, mobility, and vitality. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Maui Nui Venison: https://mauinuivenison.com/huberman  Eight Sleep: https://eightsleep.com/huberman   Waking Up: https://wakingup.com/huberman  Timestamps 00:00:00 Dr. Stacy Sims 00:02:24 Sponsors: Maui Nui, Eight Sleep & Waking Up 00:07:03 Intermittent Fasting, Exercise & Women 00:12:50 Cortisol & Circadian Rhythm, Caffeine & Training 00:17:25 Reps in Reserve, Rate of Perceived Exertion (RPE); Age & Women 00:21:06 Pre-Training Meal & Brain, Kisspeptin 00:26:45 Post-Training Meal & Recovery Window 00:29:59 Sponsor: AG1 00:31:48 Hormones, Calories & Women 00:34:24 Women, Strength Improvements & Resistance Training 00:39:10 Tool: Women & Training Goals by Age Range 00:44:16 Women, Perimenopause, Training & Longevity 00:47:14 Women & Training for Longevity, Cardio, Zone 2 00:51:42 Tools: How to Start Resistance Training, Machines; Polarized Training 00:58:23 Perform with Dr. Andy Galpin Podcast 00:59:10 Menstrual Cycle & Training, Tool: Tracking & Individual Variability 01:04:31 Tool: 10-Minute Rule; High-Intensity Training & Menstrual Cycle 01:08:36 “Train Hard & Eat Well”; Appetite, Nutrition & Menstrual Cycle 01:12:22 Oral Contraception, Hormones, Athletic Performance; IUD 01:20:57 Evaluating Menstrual Blood, PCOS; Hormones & Female Athletes 01:26:31 Iron, Fatigue; Blood Testing & Menstrual Cycle 01:29:33 Caffeine & Perimenopause; Nicotine, Schisandra 01:34:24 Deliberate Cold Exposure & Women, Endometriosis; Tool: Sauna & Hot Flashes 01:42:19 Tools: “Sims’ Protocol”: Post-Training Sauna & Performance; “Track Stack” 01:49:37 Women, Hormones & Sleep, Perimenopause & Sleep Hygiene 01:52:54 Supplements: Creatine, Water Weight, Hair Loss; Vitamin D3 01:57:21 Protein Powder; Adaptogens & Timing 02:00:11 Pregnancy & Training; Cold & Hot Exposure 02:06:19 Tool: Women in 50s & Older, Training & Nutrition for Longevity 02:09:38 Tool: Women in 20s-40s & Training, Lactate 02:12:18 Tool: What is High-Intensity Training?, Cardiovascular Sets & Recovery 02:17:22 Training for Longevity, Cellular & Metabolic Changes 02:19:30 Nutrition, 80/20 Rule 02:23:30 Listening to Self 02:26:00 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter  Disclaimer & Disclosures
    Huberman Lab
    enJuly 22, 2024

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