Towards a Cure for IPEX Syndrome: Engineered-Treg Replacement or Stem Cell Gene Editing - Rosa Bacchetta

Labor leader and activist Dolores Huerta, visual effects supervisor at Pixar Animation Studios Danielle Feinberg, and NASA aerospace engineer Aprille Ericsson join journalist Lynn Sherr to talk about what it means to be a woman and a leader in our challenging times. Sharing stories of childhood dreams, career challenges, social justice and more, the panel gives insight into their own journeys, providing inspiration for women and girls everywhere. Series: "Women in Science" [Public Affairs] [Humanities] [Show ID: 37979]

The ocean provides a bounty of essential life-supporting services. Yet, a changing climate and increasing human uses are altering marine ecosystems and their ability to continue to provide this wealth of essential services. Off the coast of California, we are lucky to have one of the worlds longest-running marine observation programs, the California Cooperative Oceanic Fisheries Investigations (CalCOFI), which has continuously and comprehensively sampled the marine environment off the California coast since 1949 to monitor the indicators and impacts of El Nino and climate change and to support effective marine management. Join marine ecologist and California Sea Grant extension specialist Erin Satterthwaite as she tells the story of CalCOFI through a series of case studies documenting how CalCOFI has been used to understand and address human and natural impacts on marine life along the California coast. Series: "Jeffrey B. Graham Perspectives on Ocean Science Lecture Series" [Science] [Show ID: 37033]

The Southern California Coastal Ocean Observing System (SCCOOS) – part of the national U.S. Integrated Ocean Observing System (IOOS) – works to collect, integrate and deliver coastal and ocean observations in order to improve safety, enhance the economy, and protect the environment. SCCOOS serves a diverse stakeholder community of managers and planners, operational decision-makers, scientists, and the general public. Join SCCOOS Executive Director Clarissa Anderson as she describes how SCCOOS technology and observational programs provide information critical to decision-making related to climate change, coastal hazards, marine ecosystems, fisheries, water quality, and marine operations. Series: "Jeffrey B. Graham Perspectives on Ocean Science Lecture Series" [Science] [Show ID: 37032]

Climate scientist Julie Kalansky discusses how drought in California and Nevada is a common occurrence, with the attendant water restrictions and threat of severe wildfires bringing the reality of climate change into sharp focus. Future climate projections for the region suggest a trend toward more extremes, including more severe and prolonged drought as well as exceptionally wet years. Learn about the science of drought and how the Scripps-based California Nevada Climate Applications (CNAP) program works to provide drought tracking and early warning in support of drought preparedness and resilience in the face of a changing climate. Series: "Jeffrey B. Graham Perspectives on Ocean Science Lecture Series" [Science] [Show ID: 37031]

Breakthroughs in genomics and targeted therapies are revolutionizing the practice of clinical oncology. Precision genomics and immunotherapy offer promise to improve outcomes in cancer, but doing so means we need to move beyond historical models for cancer diagnosis and treatment. Razelle Kurzrock, MD discusses insights from this rapidly changing field and addresses some of the ethical challenges that must be met if we are to transform the lives of patients with cancer. Series: "Exploring Ethics" [Health and Medicine] [Show ID: 36637]

Join us for a candid conversation between trailblazing women leaders about their personal journeys, their hopes, and their visions for the future. Feminist scholar and author Brittney Cooper, astronaut and scientist Kathy Sullivan, news anchor and reporter Maria Hinojosa share with author and journalist Lynn Sherr what it means to them to be leaders and inspire others. Series: "Women in Science" [Public Affairs] [Humanities] [Science] [Show ID: 36626]

As the climate warms across the globe, California is faced with adapting to a range of climate-related challenges - from drought to increased wildfire activity, to more extreme rain events. Many of these climate change phenomena work in concert to trigger catastrophic events such as post-wildfire debris flows like the one that devastated Montecito, California in January 2018. Join Scripps meteorologist Nina Oakley to learn how research is helping us understand, anticipate, and prepare for these cascading disasters in our new climate reality. Series: "Jeffrey B. Graham Perspectives on Ocean Science Lecture Series" [Science] [Show ID: 36729]

Karen Christman and Marianna Alperin discuss the newest discoveries and cutting-edge techniques for pro-regenerative biomaterials for heart and skeletal muscle with applications to cardiovascular disease and pelvic floor disorders. Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 36848]

Local fishermen, surfers, and beachgoers know that ocean temperatures off California's coast vary, often expectedly, but sometimes unexpectedly. Join Scripps oceanographer Katherine Zaba to learn how scientists deploy innovative ocean technology to monitor and understand ocean warming phenomena, like marine heatwaves and El Niño events, that affect California's coastline.  Series: "Jeffrey B. Graham Perspectives on Ocean Science Lecture Series" [Science] [Show ID: 36728]

Rita Colwell discusses her pioneering research that led to the discovery of how cholera survives between epidemics. During an open question and answer session, she addresses themes and issues covered in her recently published book, “A Lab of One’s Own—One Woman’s Personal Journey Through Sexism in Science.” Considered a science book for the #MeToo era, Colwell offers an astute diagnosis of how to fix the problem of sexism in science—and a celebration of the women pushing back. Series: "Women in Science" [Humanities] [Science] [Show ID: 36767]