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    Vaccines - Are They Safe?

    enSeptember 14, 2017
    What are parents concerned about regarding childhood vaccines?
    How has the perception of vaccines affected vaccination rates?
    What study sparked fears linking vaccines to autism?
    What does scientific consensus say about vaccine safety?
    How can parents find accurate information about vaccines?

    Podcast Summary

    • Parents' concerns about childhood vaccinesDespite scientific consensus, some parents delay or refuse vaccines due to perceived risks, leading to preventable diseases like measles. Access to accurate info is crucial for informed decisions.

      Parents are increasingly concerned about the safety of childhood vaccines due to the perception that their children are receiving too many shots too young, and that vaccines may be linked to conditions like autism or seizures. These concerns have led some parents to delay or refuse vaccines, resulting in resurgences of preventable diseases like measles. However, scientific consensus supports the safety and efficacy of the current vaccine schedule, and the risks of not vaccinating far outweigh any potential side effects. It's important for parents to have access to accurate and reliable information about vaccines to make informed decisions for their families. In the following episode of Science Versus, we will delve deeper into these concerns and explore the scientific evidence surrounding vaccines and their potential risks and benefits.

    • The Debunked Study Linking Vaccines to AutismA debunked 1998 study falsely linked vaccines to autism, but extensive scientific research continues to prove their safety and effectiveness in preventing serious diseases.

      The concern over vaccines causing autism stems from a 1998 study published in The Lancet by British doctor Andrew Wakefield. At the time, Wakefield was a respected gastroenterologist, but his research linking the measles, mumps and rubella vaccine to autism gained widespread attention and sparked fear among parents. However, the study has since been debunked due to ethical concerns and undisclosed financial conflicts of interest. Despite this, the misconception persists, fueled by anti-vaccine activists like Wakefield. It's important to remember that extensive scientific research continues to support the safety and effectiveness of vaccines in preventing serious diseases.

    • MMR Vaccine and Autism: Debunking the MythExtensive research disproves the link between MMR vaccine and autism. Andrew Wakefield's study was flawed and retracted, and no credible evidence supports the theory that mercury in vaccines causes autism.

      Despite early claims suggesting a link between autism and the measles, mumps, and rubella (MMR) vaccine, extensive scientific research has since found no credible evidence to support this theory. The MMR vaccine scare, fueled by a small, flawed study led by Andrew Wakefield, caused significant public concern and mistrust in vaccines. However, numerous studies involving over a million children in various countries using different methods all showed no connection between the vaccine and autism. Wakefield's original paper was later retracted due to ethical and scientific concerns. The ongoing debate about vaccines and autism has shifted to the possible role of mercury, a preservative used in some vaccines, but the evidence supporting this theory is also lacking. Overall, the scientific consensus remains that vaccines do not cause autism.

    • Vaccines and Autism: Debunking the MythDespite widespread concerns, there's no scientific evidence linking vaccines to autism. Thimerosal, the mercury used in some vaccines, is less harmful than other sources, and the number of vaccines a child receives at once is not linked to autism. Mercury is rarely used in vaccines today, and parents can ask for thimerosal-free versions.

      The scientific consensus is clear: there is no evidence linking vaccines containing thimerosal to autism. This claim has been extensively studied, and numerous research findings show no difference in autism rates between children who received vaccines with thimerosal and those who did not. Moreover, thimerosal, the type of mercury used in vaccines, is less harmful than other sources of mercury, such as fish or thermometers. Despite this evidence, the idea that vaccines cause autism persists, likely due to parents' concerns for their children's health. However, it is important to remember that the science on this issue is settled, and it's time to move on. Another concern some parents have is the number of vaccines children receive at once. While there are fears that this could be harmful, research suggests that there is no link between the number of vaccines a child gets and the development of autism. Additionally, mercury is no longer used in most childhood vaccines, and parents can ask their doctors for thimerosal-free versions of the influenza vaccine. In summary, the evidence supports the safety and efficacy of vaccines, and parents can trust that the scientific community is working to ensure their children's health and wellbeing.

    • Safety of Multiple Vaccines Given TogetherLimited research exists on the safety of multiple vaccines given together. While individual vaccines have been thoroughly tested, potential side effects should be weighed against disease protection.

      While individual vaccines undergo rigorous testing, there is limited research on the safety of multiple vaccines given together. Some studies suggest that vaccines do not cause asthma or allergies in children. Although vaccines can cause seizures, the risk is low, with about 1 in 3,000 children experiencing seizures after receiving the measles, mumps, and rubella vaccine, and 1 in 14,000 children after getting the DTaP vaccine. According to neurologist Ingrid Scheffer, these seizures can be frightening for parents, but the children typically recover without any long-term damage. It's essential for parents to weigh the risks of potential side effects against the benefits of protecting their children from serious diseases.

    • Discovering the truth behind vaccine encephalopathyGenetic conditions, like Dravet syndrome, may explain some cases of severe epilepsy following vaccination, but not all adverse reactions can be attributed to this cause.

      The condition called vaccine encephalopathy, which was believed to be caused by vaccines leading to severe epilepsy and brain damage, may not actually exist. Instead, some children diagnosed with vaccine encephalopathy were found to have underlying genetic conditions, specifically Dravet syndrome, which caused their seizures and epilepsy. This misdiagnosis was discovered in the early 2000s when researchers identified the gene for Dravet syndrome and tested patients. However, it's important to note that not all cases of severe epilepsy following vaccination can be explained by genetic conditions, and the Institute of Medicine's 2012 report didn't rule out the possibility of vaccine encephalopathy existing. Nevertheless, the evidence suggests that most adverse reactions to vaccines come from pre-existing conditions. This discovery is significant because it highlights the importance of considering all possible explanations for medical conditions and the potential for advances in genetic research to improve diagnosis and treatment.

    • Vaccines and the Risk of SeizuresThough rare, vaccines might trigger a child's first seizure, but the risks of not getting vaccinated, such as contracting severe diseases and their complications, are significantly greater.

      While there is little evidence that vaccines cause epilepsy, they can potentially trigger a child's first seizure. However, the risks associated with not getting vaccinated, such as contracting diseases like measles, pertussis, diphtheria, or tetanus, which can lead to severe health complications or even death, far outweigh the risks associated with vaccines. Measles, for example, can kill up to 2 people per 1,000 infected, and it's highly contagious, living in the air for up to 2 hours. The risks of vaccine-induced brain damage, such as encephalitis, are extremely rare. Heather's research showed that the benefits of vaccination far outweigh the risks, making it a crucial step in protecting individuals from serious and potentially fatal diseases.

    • Safety and efficacy of vaccinesVaccines are safe and effective, debunking common misconceptions about autism and seizures, and the risks of vaccines are significantly lower than the risks of the diseases they prevent, leading to a decline in preventable diseases if vaccination rates drop.

      The evidence supports the safety and efficacy of vaccines. Contrary to popular belief, vaccines do not cause autism, and while they can cause seizures in rare cases, they do not cause long-term harm. The risks of vaccines are significantly lower than the risks of the diseases they prevent. This is demonstrated by numerous studies, and the decline in vaccination rates can lead to a resurgence of preventable diseases. Despite the scientific consensus, fear and misinformation persist. In the next episode, we will explore the origins and reasons behind these fears. For those interested in the research behind this episode, full transcripts, including 86 footnotes, are now available by signing up for our newsletter. This episode was produced by Heather Rogers, Wendy Zuckerman, and Truti Ravindran, with production help from Rose Rimmler. It was edited by Blythe Terrell and Annie Rose Strasser, fact-checked by Michelle Harris with help from Rose Rimmler, and featured interviews with doctors Saad Omer, Neil Halsey, Paul Offit, and Alison Buttenheim.

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