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    Why one in ten children have a food allergy | Dr. Gideon Lack

    enAugust 15, 2024
    What does Professor Gideon Lack suggest about food exposure?
    How does the LEAP study impact allergy prevention guidelines?
    What role does the microbiome play in allergies?
    Why is avoiding allergens during pregnancy considered a misconception?
    What dietary practices can reduce allergy risk in infants?

    Podcast Summary

    • Food exposure during pregnancy and early childhoodExposing children to a diverse range of foods early on can help their immune system learn to distinguish friend from foe and develop long-term tolerance, contrary to current guidelines.

      Current guidelines to prevent allergies by avoiding certain foods during pregnancy and early childhood may not be effective and could even contribute to the rise of allergies. Instead, Professor Gideon Lack suggests exposing children to a diverse range of foods as early as possible to help their immune system learn to distinguish friend from foe and develop long-term tolerance. He also emphasizes that there is a misconception that avoiding allergens will protect against developing allergies, but the opposite may be true. Furthermore, there is no need for schools to ban nuts if it deprives children of healthy snacks. Instead, focus on education and awareness to keep children with allergies safe.

    • Immune system development and food allergiesEarly experiences with food and bacteria impact immune system development, but can also lead to food allergies, which are a potentially dangerous response to foreign proteins.

      Our immune system's development is strongly influenced by our early experiences with the outside world, including the foods and bacteria we encounter during infancy. This oral phase, as Freud described, plays a crucial role in our evolution, as babies actively explore their environment and build their immune system. However, this exploration can also lead to food allergies, which are a more dangerous response than food intolerances. Allergies occur when the body produces allergic antibodies against a foreign protein, triggering a cascade of events that can result in severe symptoms, including swelling, difficulty breathing, and even death. The number of food allergies has significantly increased over the last century, and while genetics may play a role, it's widely believed that environmental and cultural factors are the primary causes. Adults can also develop allergies, often to foods with proteins similar to those found in pollen, such as nuts, fruits, and vegetables. These allergies can range from mild to life-threatening, depending on the individual's reaction.

    • Food allergies and early exposureEarly exposure to foods, particularly in high-risk children, may help prevent the development of food allergies, contradicting previous guidelines.

      Food allergies, particularly to peanuts and other nuts, are becoming more prevalent in young children and are persisting into adulthood at an alarming rate. This shift is leading to a significant increase in the number of adults with persistent food allergies. The reason for this trend is not fully understood but may be linked to changes in early exposure to foods. For example, in Israel, where peanuts are introduced to babies as early as four months old, the rate of peanut allergy is almost non-existent. In contrast, in the UK and other Western countries, where peanuts are often avoided during pregnancy and early childhood, the rate of peanut allergy is much higher. A large-scale study confirmed this observation, showing a tenfold higher rate of peanut allergy in UK children compared to Israeli children. These findings challenge previous guidelines that advised avoiding certain foods during pregnancy and early childhood to prevent allergies. Instead, early introduction of these foods, particularly in high-risk children with eczema, may help prevent the development of allergies. The LEAP study, a randomized controlled trial, showed an 85% reduction in the rate of peanut allergy in children who were given peanuts regularly compared to those who avoided them. These findings suggest that early exposure to peanuts and other foods may play a crucial role in the development of food allergies and that current guidelines may need to be reevaluated.

    • Peanut introduction and allergy riskRegularly introducing peanuts to high-risk infants as early as 4-6 months old can reduce peanut allergy risk by 85% despite having low allergic antibodies, and a diverse microbiome may play a role in promoting immunological tolerance.

      A study called LEAP (Learning Early About Peanut Allergy) revealed an 85% lower risk of developing peanut allergies in high-risk infants who were regularly fed peanuts from as early as four to six months old. This was surprising as many of these infants already had low levels of allergic antibodies to peanut. The study's impact led to rapid changes in guidelines in the US, UK, and other countries, emphasizing the importance of early and regular peanut introduction. The microbiome also plays a role in this process, as studies suggest that the presence of a diverse microbiome may promote immunological tolerance. However, we are still in the early stages of understanding the exact mechanisms behind this.

    • Skin microbiome and allergiesModern hygiene practices, such as frequent bathing and use of harsh soaps, can disrupt the skin barrier and alter the microbial balance, potentially leading to allergic responses. Maintaining a healthy diet during pregnancy, exclusive breastfeeding for the first three months, and early introduction to common food allergens can help prevent allergies in high-risk infants.

      The balance of good and bad bacteria on our skin and in our gut plays a crucial role in preventing allergies. However, modern hygiene practices, such as frequent bathing and use of harsh soaps and cleansers, can disrupt the skin barrier and alter the microbial balance, potentially allowing harmful bacteria like staphylococcus aureus to grow and promote allergic responses. To help you apply this knowledge to your life, our team has created a free guide with 10 impactful discoveries from the podcast. During pregnancy, maintaining a normal, healthy diet is recommended, and there is some observational evidence suggesting that exposure to pets or farm environments may reduce the risk of food allergies. After birth, exclusive breastfeeding for the first three months and early introduction to common food allergens in small amounts can help prevent allergies in high-risk infants. These practices can make a significant difference in preventing severe, potentially life-threatening allergies. It's important to remember that being a young mother is challenging, and it's essential not to put undue pressure on yourself to follow all the advice perfectly. Instead, focus on the crucial steps that can make the most difference.

    • Food Introductions, AllergiesIntroduce complementary foods like egg, peanut, milk, wheat, sesame, kiwi, and fish around 4 months to reduce risk of severe sleeping difficulties and allergies. Learn to live with potential allergens and teach children to read labels.

      While exclusive breastfeeding for the first three to six months is beneficial, it's important to introduce complementary foods like egg, peanut, milk, wheat, sesame, kiwi, and fish to babies as early as possible, ideally around four months of age. This approach, known as early introduction, can help reduce the risk of severe sleeping difficulties and allergies. Parents should introduce these foods in a family-friendly manner and focus on the foods consumed in their household as babies will be exposed to them anyway. Schools and airlines banning certain foods is not a practical solution, and it's crucial for families to learn to live with potential allergens and teach children to read labels. New treatments, such as desensitization and monoclonal antibodies, are also promising in managing food allergies. Ultimately, it's essential to find a balance and educate families on how to manage potential allergens in their daily lives.

    • Food allergies preventionEarly and frequent exposure to common allergens like peanuts, eggs, milk, wheat, sesame, and fish can prevent up to 85% of allergies in children, according to the LEAP study. Introducing these foods at home during critical developmental stages is crucial for allergy prevention.

      Food allergies, particularly in children, have seen a significant increase in the past 50 years, with close to one in 10 children in the US and UK having an allergy. Allergies occur when the immune system mistakenly identifies harmless proteins as threats, and exposure to these proteins during critical developmental stages can help prevent allergies. The LEAP study showed an 85% reduction in babies developing peanut allergies if they were exposed to peanuts early and frequently. While peanuts, eggs, milk, wheat, sesame, and fish are common allergens, the biggest risk comes from foods in the home. Exposure to pets, such as dogs, can also reduce the risk of allergies. It's important to note that while food allergies can be life-threatening, they are also treatable, and medical interventions can help reduce the risk and severity of allergic reactions. The guidance for introducing allergens to children has shifted, and it's crucial for families to be aware of this change and to introduce these foods early and regularly to help prevent allergies.

    • Microbiome, allergiesMaintaining a healthy microbiome can help protect against allergies and improve overall health. Personalized testing and coaching from services like Zoe can help make sustainable dietary changes for better health.

      The microbiome plays a crucial role in protecting us from allergies and improving our overall health. This was a key theme discussed during the podcast episode. The expert guests shared simple yet valuable information on how maintaining a healthy microbiome can help combat allergies and improve our wellbeing. Additionally, the podcast emphasized that while listening to a weekly podcast can provide helpful advice, taking concrete steps towards better health requires more sustained effort. This is where services like Zoe come in. Zoe uses world-leading science and personalized testing to provide members with customized food recommendations based on their unique body. The app then acts as a health coach, offering weekly check-ins and daily guidance to help members make the necessary shifts in their food choices. I, for one, have seen significant improvements in my energy levels and overall health since I started following Zoe's advice. If you're looking to make sustainable improvements to your health, consider taking the first step by identifying changes to your food choices that you could make right now. Go to zoe.com/podcast to take the quiz and get 10% off as a podcast listener.

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