antivenom

How do you feel about snakes? Intrigued or terrified? In awe or creeped out? Of course, those aren’t the only options; the sight or thought of a snake can evoke many different emotions, but chances are indifference isn’t one of them. And is it any wonder? Some snakes can produce incredibly potent venoms that can seriously harm or even kill you, a characteristic that likely helped earn them their prominent role in many cultures and religions as a creature or god to be respected, if not feared. In this episode, we take a closer look at the diverse compounds that make up these venoms by exploring how they impact our bodies in the myriad ways they do and the current tools we have to combat their effects. Then we turn to evolution, not of snakes themselves but rather the role snakes may have played in primate evolution (snake detection hypothesis, anyone?) before discussing the historical development of antivenoms. We round out the episode by reviewing the current status of snakebite as a neglected tropical disease and mentioning some very exciting therapies on the horizon. Don’t missssss out on this enlightening envenoming episode today! Learn more about your ad choices. Visit megaphone.fm/adchoices

Snake venom is a wily beast. It's packed with hundreds of toxins that can attack our blood vessels, muscles and nerves. That's why snake bites kill some 100,000 people each year. On today's show — dangerous snake bites and the bizarre way we make the only thing that can save you from them: antivenom. (Spoiler alert: it takes snake milkers and stables filled with horses.) We'll also look at the groundbreaking research that could eventually revolutionise all this. We speak to Captain Pete Bethune, snake venom researchers Dr. Christina Zdenek, Professor José María Gutiérrez, Dr. Laura Albulescu and snake milker Greivin Corales.  To read more about Pete Bethune's work: https://www.earthrace.net/  Our instagram is: science_vs Check out the transcript right here: https://bit.ly/3ffV8oE This episode was produced by Wendy Zukerman with help from Meryl Horn, Rose Rimler, Michelle Dang, Nick DelRose, and Taylor White. We’re edited by Blythe Terrell. Fact checking by Erica Akiko Howard. Mix and sound design by Bumi Hidaka. Music written by Peter Leonard, Marcus Bagala, Emma Munger, and Bobby Lord. A huge thanks to all the researchers we got in touch with for this episode, including Professor Abdul Razaq Habib, Dr. Gavin Smith, Professor Abina Crean, Professor Nick Casewell, Dr. Jessicah Kurere, and Dr. Tarek Mohamed. And special thanks to Pia Gadkari, the Zukerman family and Joseph Lavelle Wilson. Learn more about your ad choices. Visit podcastchoices.com/adchoices