chemokine

“Novel role of chemokines in the ovulatory cascade and their potential application for nonhormonal contraceptive development”

The Anne Klibanski Visiting Lecture Series was created to support and advance the careers of women. These lectures offer the opportunity for women faculty from outside institutions that have hosted Anne Klibanski Scholars to present on their expertise, either alone or in tandem with an Anne Klibanski Scholar.

Presenter: Marina Cinthia Peluffo, PhD, Independent Scientist, CONICET, División de Endocrinología, Hospital de Niños Ricardo Gutiérrez, Buenos Aires, Argentina

Learning Objectives:
Upon completion of this activity, participants were able to:

• Describe the periovulatory events and the increasing evidence for the role of chemokines in regulating these crucial events in different species
• Assess our laboratory evidence regarding the chemokine receptor CCR2 and its chemokine ligands in the ovarian follicles and cumulus-oocyte complex (COC) in the rhesus monkeys and domestic cats
• Analyze the direct effect of triggering or inhibiting the CCR2 receptor within the COC using a feline model in vitro
• Evaluate the interaction between the CCR2 and epidermal growth factor receptor (EGFR, a crucial intermediate in the ovulatory cascade) systems within the feline COC
• Review and discuss the overall course of this research

Click here to watch webinar.

In season two, episode seven of the integrative health podcast Word of Mouth, IAOMT member Michael Gosswieler, DDS interviews Johann Lechner, PhD about Chemokine RANTES/CCL5 from Jawbone Cavitations

The TWiV team covers outbreaks of eastern equine encephalitis virus in the US and poliovirus in the Philippines, and explain how a chemokine induced by HIV-1 infection helps release more virus particles from cells.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker

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Links for this episode

• Poliomyelitis returns to the Philippines (Mashable, virology blog)
• EEE in the USA (Am J Trop Med Hyg)
• Chemokine helps HIV-1 release (eLIFE)
• Image credit
• Letters read on TWiV 567
• Timestamps by Jolene. Thanks!

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Brianne - History of infectious disease before/after vaccines
Alan - NIH Ham Radio Club
Rich - Renewable jet fuel from air
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Vincent - Non-polio enterovirus surveillance network

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Alexey - Periodic Table Podcasts and Videos

Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.

Vincent, Michael, and Michele reveal how a fungal protease blunts the innate immune response and promotes pathogenicity.

Subscribe to TWiM (free) on iTunes, Stitcher, RSS, or by email. You can also listen on your mobile device with the Microbeworld app.

Links for this episode

• Michele on Flint Legionella outbreak (Detroit News)
• Fungal mimicry of a mammalian aminopeptidase (Cell Host Micr)

 

This episode is sponsored by ASM Agar Art Contest and ASM Microbe 2016

Send your microbiology questions and comments (email or mp3 file) to twim@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twim.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler

Guest: Stephanie Neal

Stephanie joins the super professors to discuss the gut virome of children with serious malnutrition, caterpillar genes acquired from parasitic wasps, and the effect of adding chemokines to a simian immunodeficiency virus DNA vaccine.

 

Links for this episode

• Invitrogen Science Hero Awards 15:05
• Gut DNA viromes of twins with severe malnutrition (PNAS) 34:30
• Random forests 48:00
• Wasps engineer caterpillars (PLoS Genetics) 50:20
• Chemokine-adjuvanted SIV DNA vaccine (Mucos Immunol) 1:02:20
• Guide to chemokines (pdf)
• Role for CCR10 in IgA secreting cell accumulation (J Immunol)
• CCL28 controls IgA plasma cell accumulation (J Exp Med)
• In vivo electroporation 1:07:25, 1:09:50
• Kathy's groan (jpg)
• Image credit
• Letters read on TWiV 356 14:55

Weekly Science Picks 1:18:35, 1:45:30

Alan - Plates from Hooke's Micrographia
Rich - The Wright Brothers by David McCullough
Kathy - Spore evaporation-driven engines (video and article)
Dickson - Color variations of Pluto and Lunar total eclipse
Stephanie - The science of moldy cheese by Carl Zimmer
Vincent - But Why?

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Reed - The Bench Warmers Podcast

Send your virology questions and comments to twiv@twiv.tv

Hosts: Vincent Racaniello, Rich Alan Dove, and Kathy Spindler

Vincent, Alan, and Kathy discuss how coagulation factor X binding to adenovirus activates the innate immune system, and a novel polyomavirus associated with brain tumors in raccoons.

Links for this episode:

• Coagulation factor X activates innate immunity to adenovirus (Science)
• A decorated virus cannot hide (Science)
• Reflecting on goals for Science
• Polyomavirus associated with raccoon brain tumors (EID)
• MPNST
• Moore tumor viruses - TWiV 160
• Treating CLL with lentivirus vectors (NEJM)
• Letters read on TWiV 214

Weekly Science Picks

Alan - Parasite of the Day
Kathy - Tour of International Space Station
Vincent - Earth as Art

Listener Pick of the Week

Robin - Angell on Big Pharma
Michael - Flu jokes
Jim - Database of Ted talks; Downloadable Ted Talks

Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv