drug design

Daphne Koller is the founder and CEO of insitro, a company using AI and machine learning to engineer drug discovery. In this conversation with a16z's Vijay Pande, she discusses how an LLM for cells could revolutionize drug discovery and how to bridge the technological and cultural divide between building with atoms and building with bits.

• [0:59] Why life sciences?
• [3:42] AI in the life sciences
• [7:20] LLM for cells
• [11:55] Engineering disease and drug discovery
• [13:51] Bits vs. atoms
• [17:55] The opportunity ahead

This conversation is part of our AI Revolution series, recorded August 2023 at a live event in San Francisco. The series features some of the most impactful builders in the field of AI discussing and debating where we are, where we’re going, and the big open questions in AI. Find more content from our AI Revolution series on www.a16z.com/AIRevolution.

Our 96th episode with a summary and discussion of last week's big AI news!

Sponsor: This episode is sponsored by Zencastr, our go-to tool for recording the podcast. It is super easy to use, and there is nothing to download. Go to http://zen.ai/lastweekinai and get 30% off your first three months with a PRO account!

Outline:

• (00:00) Intro
• (01:36) Wearable, AI-powered whole-breast ultrasound system cleared by the FDA + FDA plays tooth fairy, awards clearance to VideaHealth's cavity-spotting AI 
• (06:40) Another Firing Among Google’s A.I. Brain Trust, and More Discord 
• (12:30) AI Model Can Accurately Detect Multiple Retinal Diseases in Real Time
• (12:50) Intel wins DARPA RACER-Sim program
• (14:00) Mayo researchers use AI to detect weak heart pump via patients' Apple Watch ECGs
• (17:50) Tsinghua U & BAAI’s CogView2 Achieves SOTA Competitive Text-to-Image Generation With 10x Speedups 
• (23:13) In The Latest Research From The University Of Toronto, Machine learning-Based Approach Speeds Up The Counting Of Microplastics - 
• (23:52) Northeastern U & Microsoft Expand StyleGAN’s Latent Space to Surpass the SOTA on Real Face Semantic Editing 
• (24:55) Microsoft AI Researchers Develop MoLeR: A Deep Learning-Based Generative Model That Enables Efficient Drug Design 
• (26:50) Ad break
• (28:40) UK Regulators' Path for AI Starts with Auditing Algorithms 
• (32:16) A unique machine-learning model predicts homelessness among US soldiers before their transition to civilian life
• (35:45) Researchers Taught A.I. to Write Wine and Beer Reviews and They're Pretty Convincing
• (39:33) T-SNE to view and order your Spotify tracks
• (42:40) What’s New in Spot | Boston Dynamics
• (44:17) Outro