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    flt3

    Explore " flt3" with insightful episodes like "Using Available Evidence and Guidelines for Managing an Evolving AML Treatment Paradigm", "Acute Myeloid Leukemia with FLT3 Mutations" and "Future Treatment Strategies for Acute Myeloid Leukemia—Emerging Targeted Therapy Combinations and Beyond" from podcasts like ""ClinicalXchange Oncology podcasts", "Oncology Today with Dr Neil Love" and "CCO Oncology Podcast"" and more!

    Episodes (3)

    Using Available Evidence and Guidelines for Managing an Evolving AML Treatment Paradigm

    Using Available Evidence and Guidelines for Managing an Evolving AML Treatment Paradigm

    Presenter:

    Gail J. Roboz MD
    Professor of Medicine
    Director, Clinical and Translational Leukemia Program
    Weill Medical College of Cornell University
    New York-Presbyterian Hospital
    New York, New York, United States

    This brief program will begin with a review of NCCN Guidelines® Recommendations for the treatment of AML in individuals 60 years of age or older. Next, the results of the BRIGHT AML 1003 trial comparing glasdegib + LDAC to LDAC alone, the VIALE-A trial comparing venetoclax + azacitidine vs azacitidine alone, and a comparison of CPX-351 vs standard of care cytarabine + daunorubicin (7 + 3 regimen) for induction and consolidation, will be reviewed. The faculty will discuss FLT3 and IDH inhibitor approvals for AML, IDK differentiation syndrome, and measuring MRD in AML. Finally, results of a trial examining oral azacitidine and a meta-analysis of 5 trials examining gemtuzumab ozogamicin will be reviewed.https://www.clinical-care.org/resource-center-details/using-available-evidence-and-guidelines-for-managing-an-evolving-aml-treatment-paradigm

    Follow along with the slideset located here:
    https://bit.ly/3lJNHYC  

    Acute Myeloid Leukemia with FLT3 Mutations

    Acute Myeloid Leukemia with FLT3 Mutations
    For this special edition of Oncology Today, I met with Dr Keith Pratz from the University of Pennsylvania in Philadelphia to discuss recently published and emerging research in the use of FLT3 inhibitors for patients with acute myeloid leukemia. CME information and select publications here (http://www.researchtopractice.com/OncologyTodayAMLFLT320).

    Future Treatment Strategies for Acute Myeloid Leukemia—Emerging Targeted Therapy Combinations and Beyond

    Future Treatment Strategies for Acute Myeloid Leukemia—Emerging Targeted Therapy Combinations and Beyond

    In this episode, Naval G. Daver, MD, discusses promising investigational agents and treatment combinations in clinical trials for patients with newly diagnosed and relapsed/refractory AML, including:

    • FLT3 inhibitors crenolanib and quizartinib
    • Anti-CD47 antibody magrolimab
    • IMGN632, a CD123 antibody–drug conjugate
    • Anti-CD70 antibody cusatuzumab
    • APR-246, targeting the TP53 mutation

    Content is part of an online CME program supported by an educational grant from Daiichi-Sankyo.

    Link to full program, including a ClinicalThought commentary:  https://bit.ly/2Y2uCG2

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