influenza

Could we eliminate the number one cause of death? Neil deGrasse Tyson and co-hosts Chuck Nice and Gary O’Reilly go to medical school to learn about heart health, the impacts of COVID, and the cardiovascular disease epidemic with physician Dr. Lipi Roy.

NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free here: 
https://startalkmedia.com/show/beating-time-dodging-the-number-one-killer-with-dr-lipi-roy/

Thanks to our Patrons Kaleda Davis, Saúl Franco, Jake Egli, Josh Rolstad, Roxanne Landin, jamie brutnell, and Bailey Manasco for supporting us this week.

Photo Credit: Nephron, https://creativecommons.org/licenses/by-sa/3.0 target=_blank>CC BY-SA 3.0, via Wikimedia Commons

In this episode of a16z bio Journal Club, general partner Vijay Pande, bio deal team partner Andy Tran, and bio editor Lauren Richardson discuss a novel CRISPR-Cas-based anti-viral strategy.

The discussion covers the differences between this newly developed prophylactic strategy, traditional vaccines, and anti-viral drugs; how this strategy can be engineered to target a huge range of coronavirus and influenza strains; and the next steps needed to go from paper to practice:

• “Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza” in Cell (April 2020), by Timothy Abbott, Girija Dhamdhere, Yanxia Liu, Xueqiu Lin, Laine Goudy, Leiping Zeng, Augustine Chemparathy, Stephen Chmura, Nicholas Heaton, Robert Debs, Tara Pande, Drew Endy, Marie La Russa, David Lewis, and Lei Qi

a16z Journal Club (part of the a16z Podcast), curates and covers recent advances from the scientific literature -- what papers we’re reading, and why they matter from our perspective at the intersection of biology & technology (for bio journal club). You can find all these episodes at a16z.com/journalclub.