ketone supplements

Join us on this episode of the Flex Diet Podcast for a riveting conversation with Dr. Dwayne Jackson as we explore the world of neuro-protection and the critical role nutrition plays in it. We dig into the potentially harmful effects of inflammation and how it can lead to chronic traumatic encephalopathy (CTE). We also highlight the importance of entering sports activities in the least inflammatory state possible and how a balanced diet and supplements can assist.

If you enjoyed this podcast, you can get more from me at MikeTNelson.com/podcast. You can see all the other podcasts and guest episodes I’ve done. Then if you scroll down, you can subscribe to my Fitness Insider Newsletter.

Episode Chapters:

• (0:00:01) - Neuro-Protection and Nutrition
• (0:07:57) - Colorful Diet
• (0:13:01) - Exploring Variety in Food and Supplements
• (0:24:38) - CBD's Impact on Immunosuppression and Neurology
• (0:29:43) - Microdosing Mushrooms and Lyon's Main
• (0:39:13) - BHB, Ketone Supplements for Concussions
• (0:51:40) - Podcast Disclaimer for Health Advice

Connect with Dr. Dwayne Jackson:

• Instagram
• Website

Previous Podcast:

• Flex Diet Podcast Episode 202: Cold water immersion and the body's regulation systems: An interview with Dr. Dwayne Jackson

View all show notes and timestamps on the KoopCast website.

Episode overview:

Brendan is an Associate Professor of Sport and Exercise Physiology and Head of School for the School of Health and Human Performance at DCU. His current research investigates skeletal muscle function and adaptation across the life course, with special interest in the synergy between nutrition and exercise interventions ranging from athletes to older adults. His research group performs human trials involving both acute and chronic interventions for outcomes around performance (physical and cognitive), recovery, and adaptation. It has employed various experimental designs and has been complimented by molecular analysis tools, including transcriptomics, proteomics, and metabolomics. Nutrients recently and presently under investigation include caffeine, creatine, omega-3 fatty acids, resveratrol, leucine, protein hydrolysates, beetroot juice, and exogenous ketones.

Brendan received his BSc in Sport and Exercise Science from the University of Limerick in 2003, MSc in Sport and Exercise Nutrition from Loughborough University in 2004, and Ph.D. from Dublin City University in 2008 before completing two years of post-doctoral training with Prof. Juleen Zierath’s Integrative Physiology group at the Karolinska Institute, Sweden. His doctoral studies focussed on skeletal muscle adaptation to exercise, and in particular, the continuity between acute molecular responses to individual bouts of exercise and adaptations induced by exercise training, whereas his post-doctoral training utilized animal models and in vitro cell systems to investigate the transcriptional regulation of skeletal muscle development and mechanisms of insulin resistance. He joined the faculty in the School of Public Health, Physiotherapy, and Sport Science at University College Dublin in 2011, where he spent five years before moving to DCU. He is also a Visiting Research Scientist at the Florida Institute for Human and Machine Cognition, Pensacola, FL, USA, and a Principal Investigator at the National Institute for Cellular Biotechnology at DCU.

Outside of academia, through his sporting career as an inter-county Gaelic footballer with Sligo from 2003 to 2017, Brendan has had a lifelong association with sport, training, and performance at all levels of competition, from grassroots to elite level, and also practices in the field as a performance nutritionist with emphasis on field-based team sports, and endurance athletes.

Episode highlights:

(25:27) The “preferred energy source”: media sources, ketones become the dominant fuel in the brain during starvation, dominant does not mean preferred, ketogenesis is a survival mechanism, exogenous ketones can rescue heart failure

(35:30) Ketones as glycogen sparing: Tour de France background, mechanistic basis, two existing relevant studies, one showed glycogen sparing and one showed no difference, differences in methods, the theory is solid but the proof is lacking

(57:27) Ketones for protein generation study: design, downstream markers from mTOR increase with ketones, protein synthesis was not measured directly but is likely, once again the mechanistic theory is promising but the proof is pending, ketones for sleep

Additional  resources:

Papers discussed-

Exogenous Ketone Supplements in Athletic Contexts: Past Present and Future

Ketone monoester ingestion increases postexercise serum erythropoietin concentrations

Our guest is Dr. Mary Newport, a board-certified pediatrician and neonatologist with over thirty years of experience in her field. She is also a Certified Ketogenic Nutrition Specialist through the American Society of Nutrition and an international speaker on the benefits of ketones as an alternative fuel for the brain. Dr. Newport is the author of three books, including "Clearly Keto for Healthy Brain Aging and Alzheimer's Prevention." Her groundbreaking research and experience with ketones have made her a leading authority on the subject. In 2008, Dr. Newport implemented a ketogenic nutritional intervention using coconut and medium-chain triglyceride oil that drastically improved her husband's early-onset Alzheimer's disease.

On this Episode: 

• Introduction to Dr. Mary Newport
• 3:53 Dr. Mary Newport's Journey to Discovering the Benefits of Ketones for Brain Health in Alzheimer's Patients.
• 17:54 The Miracle of MCT Oil and Ketones
• 20:58 Benefits of Ketones for Brain Health and Alzheimer's Disease
• 27:15 Roadblocks Dr. Newport Faced Trying to Share Her Research on MCT Oil and Alzheimer's
• 33:00 Importance of Nutrition in Diabetes and Dementia
• 37:19 Origins of the Low-Fat Diet Myth
• 48:35 MCT oil for brain health and preventing Alzheimer's disease
• 57:29 Promoting the Benefits of Ketones for Alzheimer's Disease

Show Links:

• Link to Dr. Mary Newport’s bio:

Website: http://coconutketones.com

Books: 

Available on Amazon and many other book websites and stores

Clearly Keto for Healthy Brain Aging and Alzheimer’s Prevention (November 29, 2022)

Amazon Books: https://amzn.to/3sXbrMR (to preorder)

The Complete Book of Ketones: A Practical Guide to Ketogenic Diets and Ketone Supplements (2019)  

Amazon Books: https://amzn.to/2AxBcLp 

The Coconut Oil and Low Carb Solution for Alzheimer’s, Parkinson’s, and Other Diseases (2015) 

Amazon Books: https://amzn.to/2BaClJE  

Alzheimer’s Disease: What If There Was a Cure?  The Story of Ketones. (2011, 2 nd edition 2013, 3 rd edition

coming September 2023)  Amazon Books: https://amzn.to/3d4n0HP 

• Call to action for listeners: Follow ketones and Coffee Podcast on Instagram ( https://www.instagram.com/keton.esncoffee ), Youtube (

Listen on: Apple Podcasts   Spotify

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