loading dose

In this episode, Marion Elligsen, BScPhm, MSc, RPh, ACPR; Keith S Kaye, MD, MPH; and Andrew Shorr, MD, MPH, MBA, discuss key considerations for selecting empiric antibiotic regimens in patients with HABP/VABP in the intensive care unit, including: 

• The role of novel β-lactam/β-lactamase inhibitor combinations
• Use of clinical predictions scores (eg, Drug Resistance in Pneumonia [DRIP] score) to predict risk for pneumonia caused by multidrug-resistant pathogens
• Application of rapid diagnostic testing in critically ill patients with pneumonia, including current limitations
• Implementation of advanced antibiograms and clinical prediction scores
• Clinical utility of biomarkers for pneumonia (eg, procalcitonin)
• Application of updated nosocomial pneumonia classifications in clinical practice

Faculty:
Marion Elligsen, BScPhm, ​ MSc, RPh, ACPR​
Practice-Based Researcher​
Sunnybrook Research Institute​
Antimicrobial Stewardship Pharmacy Lead​
Department of Pharmacy​
Sunnybrook Health Sciences Centre​
Toronto, Ontario, Canada​

Keith S. Kaye, MD, MPH
Chief  
Division of Allergy, Immunology and Infectious Diseases
Professor of Medicine
Rutgers Robert Wood Johnson Medical School
New Brunswick, New Jersey

Andrew Shorr, MD, MPH, MBA​
Director​
Pulmonary and Critical Care Medicine​
Medstar Washington Hospital Center​
Washington, DC​

Content based on a CME program supported by an educational grant from Merck Sharp & Dohme Corp. 

Link to full program:
https://bit.ly/3HaZpYw

Link to downloadable slideset:
https://bit.ly/3UxHoqr

Does loading vancomycin lead to achieving target levels within the first 24 hours? Does it increase the risk of nephrotoxicity?
 
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References:
All references for Episode 60 are found on my Read by QxMD collection

Disclaimer: 
The information contained within the  ER-Rx podcast episodes, errxpodcast.com, and the @errxpodcast Instagram page is for informational/ educational purposes only, is not meant to replace professional medical judgement, and does not constitute a provider-patient relationship between you and the authors. Information contained herein may be accidentally inaccurate, incomplete, or outdated, and users are to use caution,  seek medical advice from a licensed physician,  and consult available resources prior to any medical decision making. The contributors of the ER-Rx podcast are not affiliated with, nor do they speak on behalf of,  any medical institutions, educational facilities, or other healthcare programs.

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Disclaimer:

The information contained within the ER-Rx podcast episodes, errxpodcast.com, and the @errxpodcast Instagram page is for informational/ educational purposes only, is not meant to replace professional medical judgement, and does not constitute a provider-patient relationship between you and the authors. Information contained herein may be accidentally inaccurate, incomplete, or outdated, and users are to use caution, seek medical advice from a licensed physician, and consult available resources prior to any medical decision making. The contributors of the ER-Rx podcast are not affiliated with, nor do they speak on behalf of, any medical institutions, educational facilities, or other healthcare programs.