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    maximal

    Explore "maximal" with insightful episodes like "Seibertron.com Twincast / Podcast #327 "Review of the Beasts"", "Wie alt können Menschen maximal werden?", "Maximal spridning för minimal rysk propaganda, KD hotar SR med bojkott efter flera översättningsfel, pressfrihetsindex prövat i praktiken", "Seibertron.com Twincast / Podcast #278 "The Return of Rodimus Prime"" and "Snicksnack? Ja, tack!, Maximal harmoni - Galet!! & Mycel-mys med Spanarna" from podcasts like ""Seibertron.com Transformers Twincast/Podcast", "CheckGPT", "Medierna", "Seibertron.com Transformers Twincast/Podcast" and "Spanarna"" and more!

    Episodes (46)

    Seibertron.com Twincast / Podcast #327 "Review of the Beasts"

    Seibertron.com Twincast / Podcast #327 "Review of the Beasts"
    Seibertron.com Twincast / Podcast #327: Review of the Beasts
    Rise of the Beasts has hit movie theaters across the globe and the Seibertron.com Twincast Podcast takes most of episode 327 to talk about the film. Reflections on its characters occur throughout, including both the robot and human cast with standouts such as Mirage and Noah. The plot is discussed in-depth alongside speculation of what may have been left on the cutting room floor that could have helped the story along. Continuity comes up as well, leaving the ultimate decision on prequel vs reboot status to the listener. The G.I. Joe presence at the end of the film also leads to informal predictions of what may occur in the future. After some retrospective thought about its toyline, the cast quickly checks out the upcoming Buzzworthy Bumblebee troop-builder 4-pack before the episode concludes with a quick round of the recurring Bragging Rights segment.

    Maximal spridning för minimal rysk propaganda, KD hotar SR med bojkott efter flera översättningsfel, pressfrihetsindex prövat i praktiken

    Maximal spridning för minimal rysk propaganda, KD hotar SR med bojkott efter flera översättningsfel, pressfrihetsindex prövat i praktiken

    Kreml annonserar, Twitter exploderar, svenska medier rapporterar. Totalt okritisk SVT-dokumentär om Christer Björkmans dröm att ta Melodifestivalen till USA. KD hotar SR med bojkott efter flera översättningsfel. Vi testar Reportrar utan gränsers pressfrihetsindex i praktiken.

    Lyssna på alla avsnitt i Sveriges Radio Play.

    Seibertron.com Twincast / Podcast #278 "The Return of Rodimus Prime"

    Seibertron.com Twincast / Podcast #278 "The Return of Rodimus Prime"
    Seibertron.com Twincast / Podcast #278: The Return of Rodimus Prime
    Episode 278 of the Seibertron.com Twincast Podcast starts off with some catching up with former podcast crew member RodimusConvoy13, with no set topic and general talk about recent Transformers toys. Next up, we dive into the latest War for Cybertron Battle Across Time set with earth-mode Sideswipe and a throw back to Beast Wars II, Maximal Skywarp. With the reveal of Kingdom Tracks, we knew it would only be a matter of time until we saw Kingdom Road Rage unofficially revealed, so some very brief discussion occurs about it. Next, we discuss the new images of what looks to be Kingdom Deluxe Class Waspinator. It looks like we will be seeing more in the Premium Finish line with the latest reveal from Takara Tomy Mall, SS-02 Optimus Prime from the Bumblebee film and WFC-02 Megatron. With all that has been revealed recently, the crew discusses their thoughts on different character iterations throughout the years before the episode concludes with the recurring Bragging Rights segment.

    Snicksnack? Ja, tack!, Maximal harmoni - Galet!! & Mycel-mys med Spanarna

    Snicksnack? Ja, tack!, Maximal harmoni - Galet!! & Mycel-mys med Spanarna

    Helena von Zweigbergk: Snicksnack? Ja, tack! Göran Everdahl: Maximal harmoni - Galet!! Katarina Barrling: Mycel-mys.

    Lyssna på alla avsnitt i Sveriges Radio Play.

    Spanarna Helena von Zweigbergk, Göran Everdahl & Katarina Barrling bjuder på framtidsvisioner med humor

    Helena von Zweigbergk: Snicksnack? Ja, tack!

    Göran Everdahl: Maximal harmoni - Galet!!

    Katarina Barrling: Mycel-mys.

    Spanarna är ett program och en podd för dig som gillar samhällsspaning med humor. Tre skarpsynta personligheter försöker avläsa trender i vår vardag och ge oss sina framtidsvisioner.

    Programledare Ingvar Storm.

    spanarna@sverigesradio.se

    Seibertron.com Twincast / Podcast #270 "An Ox, a Seagull and a Monster"

    Seibertron.com Twincast / Podcast #270 "An Ox, a Seagull and a Monster"
    Seibertron.com Twincast / Podcast #270: An Ox, a Seagull and a Monster
    On episode 270 of the Seibertron.com Twincast Podcast the Transformers talk begins with discussion on the soon to be released Haslab Unicron in light of the final pre-shipment update from Hasbro, as well as the first video reviews, being released around the internet. Next up, product codes have been leaked that include the likes of Beast Machines T-Wrecks, the Sweeps and Wreck-Gar, among other potential exclusives and movie figures. A surprise rumor about Movie Masterpiece Optimus Prime from the Bumblebee film is brought up next. The chat then shifts to Super7's new Ultimates featuring Optimus Prime, Ghostly Starscream, Bazai-Tron and Bombshell. Rumors about Beast Wars toy reissues from the Transmetals segment of the line prompt speculation and wishful thinking about what the cast would like to see come out of that, if true, before a listener question is answered. The Beast Wars talk concludes with a discussion on the recently released Beast Wars #1 from IDW Publishing, followed by the recurring Bragging Rights segment to end the episode.

    Episode 093 - Bobby Maximus: Maximum Motivation for Maximal Results

    Episode 093 - Bobby Maximus:  Maximum Motivation for Maximal Results
    In Episode 093, we spend one of our final sessions of 2020 with Bobby Maximus. Bobby talks about the motivation he used and still uses today to develop and drive his career. Hailing from a small town in Northern Ontario, Bobby managed to work his way up the tactical and sporting ladder using a blue collar attitude. He also talks about how training and fitness adds significant value to his life and he helps others to find that same enjoyment and motivation around physical preparation and fitness. Bobby continues to apply this approach to his own daily training, even as he approaches middle age, keeping his workouts fresh and varying up the programming as he feels necessary. Whatever it takes to maintain his enjoyment of the process of exercising and maximizing his potential.

    During his career Bobby Maximus has been featured in numerous workout publications, conducted many seminars and worked with numerous Tier One Assets and Special Forces groups within the United Stated military. Bobby is also a regular contributor to Men’s Health Magazine and is the Keeper Of Authenticity at Lalo Tactical. In the past, Bobby was a police officer in serving as a member of the Peel Regional Police Force as well as The Toronto Police Service. He spent time on the road, as part of the Toronto Anti-Violence Intervention Strategy Team, and also as a Defensive Tactics Instructor. He has also competed in numerous fight competitions across North America. In 2006 he fought in UFC 58, UFC 62 and Ultimate Fight Night 5, where he won Submission of the Night. Robert also starred on Spike TV's The Ultimate Fighter series, was the Ring of Fire light-heavyweight champion and fought for an amateur world kickboxing championship. In addition to his policing, training and fighting career, Bobby earned a Bachelor of Arts degree from the University of Western Ontario with a double major in Psychology and English. He also earned a Bachelor of Education graduate degree from Lakehead University.

    You can find out more information on Bobby Maximus via the following links:

    Website: https://www.bobbymaximus.com/

    Instagram: https://www.instagram.com/bobbymaximus/

    Twitter:https://twitter.com/bobbymaximus


    The D&D Fitness Radio podcast is available at the following locations for downloadable audio, including:

    iTunes – https://itunes.apple.com/us/podcast/d-d-fitness-radio-podcast/id1331724217

    iHeart Radio – https://www.iheart.com/podcast/dd-fitness-radio-28797988/

    Spreaker.com – https://www.spreaker.com/show/d-and-d-fitness-radios-show

    Spotify – https://open.spotify.com/show/5Py2SSPA4mntNwYRm0Opri


    You can reach both Don and Derek at the following locations:

    Don Saladino:
    http://www.DonSaladino.com
    Twitter and Instagram - @DonSaladino
    YouTube - http://www.youtube.com/donsaladino

    Derek M. Hansen:
    http://www.SprintCoach.com
    Twitter and Instagram - @DerekMHansen
    YouTube - http://youtube.com/derekmhansen

    The High Prevalence of Exercise Intolerance in Adult Survivors of Childhood Cancer Is Predictive of All-Cause Mortality

    The High Prevalence of Exercise Intolerance in Adult Survivors of Childhood Cancer Is Predictive of All-Cause Mortality

    This podcast describes a study examining aerobic capacity in a cohort of over 1200 adult survivors of childhood cancer and related impairments of cardiac, pulmonary and neuromuscular body systems, to understand how aerobic capacity influences all-cause mortality.

    TRANSCRIPT

    This JCO Podcast provides observations and commentary on the JCO article 'Exercise Intolerance, Mortality, and Organ System Impairment in Adult Survivors of Childhood Cancer' by Ness et al. My name is Kristin Campbell, and I am a licenced physical therapist and associate professor in the Faculty of Medicine at the University of British Columbia in Vancouver, Canada. My oncologic specialty is in rehabilitation, primarily related to breast cancer.

    Exercise intolerance is a global measure of functional capacity that reflects the complex integration of body systems. It is well established in the general population that exercise intolerance is predictive of future cardiovascular health and mortality. Whether this relationship also existed for adult survivors of childhood cancer was examined by Ness and colleagues in the article that accompanies this podcast. . In the largest study to date of its kind, this manuscript reports on a comprehensive and methodologically rigorous examination of exercise intolerance measured by a gold standard maximal cardiopulmonary exercise test in over 1200 adult survivors of childhood cancer who are part of the St. Jude’s Lifetime Cohort Study.

    The first main finding is the low levels of exercise capacity in this sample of childhood cancer survivors despite a relatively young mean age of 35 years. The observed maximal aerobic capacity, or VO2peak, ranged on average between 25-27 ml/kg/min, which fall into the “poor” or “very poor” categories of age and sex matched normative values. Compared to 285 community controls who were friends or family members of the cohort patients, the observed maximal aerobic capacity values for childhood cancer survivors were on average 22% lower. In fact, these values are actually more consistent with values seen in healthy adults in their seventies or eighties. Furthermore, the low value of maximal aerobic capacity may also be an underestimate. Thirteen percent of individuals in the St. Jude’s cohort who agreed to participate in the study were not cleared to undertake the maximal cardiopulmonary exercise test due to recent diagnosis of cardiac or pulmonary disease, or lab values and symptoms indicating cardiac or pulmonary issues. This suggests that the prevalence of exercise intolerance may be even greater in a real-world clinical setting than that observed in this cohort.

    To examine the association between exercise intolerance and mortality, the authors defined exercise intolerance as a maximal aerobic capacity of < 85% of predicted VO2peak. Using this approach. 56% of childhood cancer survivors were categorized with exercise intolerance compared to only 26% in controls. In addition to the high prevalence, exercise intolerance in childhood cancer survivors increased hazard of death nearly four-fold compared to those without exercise intolerance. Of the 24 deaths observed, 21 were seen in those categorized as having exercise intolerance compared to only 3 in those categorized without exercise intolerance. This highlights the potential importance of developing and implementing effective interventions that aim to increase physical activity levels and exercise tolerance in childhood cancer survivors with the goal of improving long-term health and survival.

    A unique feature of this study is that the authors also undertook comprehensive measures of host, treatment, and lifestyle factors to better understand how these factors influence exercise intolerance. These additional measures included cardiac imaging at rest, autonomic response, measured by blood pressure response to the maximal graded exercise test, standard pulmonary function testing, quadriceps strength testing, and peripheral sensorimotor function using the modified total neuropathy scale. This data provides a rare look into the acute and chronic responses to exercise of the cardiovascular, pulmonary, autonomic and neuromuscular systems in those exposed or not exposed to cardiotoxic agents and will appeal to those an interest in exercise physiology. Odds of exercise intolerance were highest with reporting <150 minutes per week of moderate to vigorous physical activity, lower quadriceps strength, chronotropic incompetence, FEV1 <80% of predicted, non-white race, and poorer diet quality. These findings provide guidance around key factors that could be used to design effective interventions and monitor response to interventions, with a goal to improve exercise tolerance in childhood cancer survivors.

    Of note, the type of treatment received impacted the presentation of exercise intolerance. Lower exercise tolerance was observed in individuals who received >350 mg/m2 of anthracyclines, >30 Gy of chest radiation, >20 Gy of cranial radiation and receipt of carboplatin. As a result, the authors suggest that even asymptomatic childhood cancer survivors who have received these treatments be screened by medical providers for any required medical management prior to recommending or implementing an exercise program.  Furthermore, while ejection fraction of <53% was not associated with exercise intolerance, global longitudinal strain > 1.5 SD above age- and sex-predicted increased the odds of exercise intolerance with an odds ratio of 1.71 in those exposed to cardiotoxic agents and an odds ratio of 1.29 in those not exposed to cardiotoxic agents. The authors suggest that the use of echocardiology derived strain be expanded from current published guidelines from the American Society of Clinical Oncology on Prevention and Monitoring of Cardiac Dysfunction to identify early cardiac dysfunction in childhood cancer survivors with exercise intolerance and normal ejection fraction.

    The study does have some key limitations. It is cross-sectional in design, making it difficult to assign temporal relationships between impairments in body systems and exercise tolerance. For example, is it the treatment that causes impairments in body systems that then limit exercise tolerance, or does situational inactivity due to side-effects of cancer treatment drive exercise intolerance and this in turn negatively impacts the exercise response of body systems? Furthermore, while there was a high participation rate and participants did not differ from non-participants by age, race or sex, not all eligible survivors enrolled. This may over or underestimate the prevalence of exercise intolerance or impact on mortality.

    In considering the implications of these findings to clinical oncology, the authors acknowledge that adult survivors of childhood cancer face unique challenges in engaging in physical activity. In light of the high prevalence of exercise intolerance in childhood cancer survivors and the association to all cause mortality, the authors suggest that survivors may require referral to trained exercise specialists to learn how to accommodate specific impairments and deficits in order to reap the benefits of engaging in exercise. In the United States, the appropriate exercise specialists could include physical therapists, occupational specialists, certified exercise physiologists or physical medicine and rehabilitation specialists. Oncology providers are encouraged to include these individuals on their care teams and establish a connection to available programming in their healthcare facility or community to provide adult survivors of childhood cancer with greater access to appropriate exercise programming aimed at improving exercise tolerance.

    This concludes this JCO podcast. Thank you for listening.