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    monoclonal antibody

    Explore " monoclonal antibody" with insightful episodes like "Ep 106: A new RSV shot for kids--should your child get it? with Michael Hochman MD, MPH", "184. Revisiting Apoquel vs. Cytopoint", "Preparing for the Fall: New RSV Vaccine Approvals", "Amgen Launches Humira Biosimilar Amjevita + Potential New Blood Test for Early Detection of Alzheimer's" and "Should We Be Concerned About Resistance and Development of New Variants With COVID-19 Antiviral Therapy?" from podcasts like ""Ask Dr Jessica", "The Derm Vet Podcast", "CCO Infectious Disease Podcast", "Xtalks Life Science Podcast" and "CCO Infectious Disease Podcast"" and more!

    Episodes (17)

    Ep 106: A new RSV shot for kids--should your child get it? with Michael Hochman MD, MPH

    Ep 106: A new RSV shot for kids--should your child get it? with Michael Hochman MD, MPH

    Today’s episode features Dr Michael Hochman,to discuss the newly approved FDA product to prevent RSV in children, Nirsevimab (sold under the brand name Beyfortus). Recently there have been two RSV vaccines approved for adults—one for individuals over 60 years old, and one for use in pregnancy to prevent RSV in infants.  On today’s podcast, the conversation will focus on  Nirsevimab, a shot that has been approved by the FDA for all babies up to 8 months old and  a second shot for infants up to 19 months who are considered to be at high risk of severe RSV infection.   Nirsevimab is a monoclonal antibody with activity againast respiratory syncytial virus (RSV).  On today's podcast we will review the benefits and potential side effects of Nirsevimab.

    Dr Michael Hochman is a Harvard Medical School graduate,  a Robert Wood Johnson Clinical Scholars Fellow at UCLA where he received his masters in public health, and he is the founding editor of a book series called “ 50 studies every doctor should know”, so he has a keen interest in reviewing medical studies.  




    Dr Jessica Hochman is a board certified pediatrician, mom to three children, and she is very passionate about the health and well being of children. Most of her educational videos are targeted towards general pediatric topics and presented in an easy to understand manner.

    Do you have a future topic you'd like Dr Jessica Hochman to discuss? Email Dr Jessica Hochman askdrjessicamd@gmail.com.

    Follow her on Instagram: @AskDrJessica
    Subscribe to her YouTube channel! Ask Dr Jessica
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    Subscribe to her mailing list: www.askdrjessicamd.com

    The information presented in Ask Dr Jessica is for general educational purposes only. She does not diagnose medical conditions or formulate treatment plans for specific individuals. If you have a concern about your child's health, be sure to call your child's health care provider.

    Preparing for the Fall: New RSV Vaccine Approvals

    Preparing for the Fall: New RSV Vaccine Approvals

    In this episode, Helen Y. Chu, MD, MPH, shares updates on RSV vaccines, including:

    • An overview of vaccine candidates under investigation
    • Recently FDA-approved RSV vaccines for older adults
    • Considerations for the next respiratory viral season
    • Coadministration of RSV vaccines with other respiratory viral vaccines (eg, influenza, SARS-CoV-2)
    • Target populations for RSV vaccination
    • RSV prevention in infants with the maternal vaccine and monoclonal

    Faculty:

    Helen Y. Chu, MD, MPH
    Associate Professor of Medicine
    Division of Allergy & Infectious Diseases
    University of Washington 
    School of Medicine
    Seattle, Washington

    Link to full program: https://bit.ly/3nb25xehttps://bit.ly/3nb25xe

    Link to downloadable slides: https://bit.ly/3TsXym5

    Amgen Launches Humira Biosimilar Amjevita + Potential New Blood Test for Early Detection of Alzheimer's

    Amgen Launches Humira Biosimilar Amjevita + Potential New Blood Test for Early Detection of Alzheimer's

    In this episode, Ayesha talked about the launch of Amgen’s Amjevita, the first Humira biosimilar to hit the market. Amjevita received FDA approval in 2016 and after a legal settlement with Humira maker AbbVie, has finally reached market launch. AbbVie has been embroiled in legal battles over accusations of overpatenting and price hiking to block Humira biosimilar competition. Hear more about Amjevita and how 2023 is a big year for Humira biosimilars with over half a dozen more launching this year.

    Ayesha also discussed new Alzheimer’s research from Kings College London that could lead to the development of a blood test for the early detection of the disease. The research found that certain biomarkers in the blood of patients with mild cognitive impairment (MCI), which some Alzheimer’s patients develop before being diagnosed with the disease, could predict the onset of Alzheimer’s up to 3.5 years before a clinical diagnosis is made. Learn more about the new research in this episode.

    Read the full articles here:

    Amgen’s Amjevita Enters Market as First Humira Biosimilar, But at Two Different Price Points

    Early Detection of Alzheimer’s Disease: New Research Shows How a Blood Test Could Lead to Earlier Diagnosis

    For more life science and medical device content, visit the Xtalks Vitals homepage.

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    Should We Be Concerned About Resistance and Development of New Variants With COVID-19 Antiviral Therapy?

    Should We Be Concerned About Resistance and Development of New Variants With COVID-19 Antiviral Therapy?

    Fernando Carnavali, MD; Rasika Karnik, MS, MD; Renslow Sherer, MD; and Joseph Torrisi, PharmD, BCIDP, discuss COVID-19 treatments and the possibility for antiviral resistance, including:

    • Treatment resistance mechanisms
    • COVID-19 testing
    • COVID-19 treatments, including antivirals and monoclonal antibodies

    Presenters:
    Fernando Carnavali, MD
    Associate Professor of Medicine
    Division Chief
    General Internal Medicine
    Department of Medicine
    Site Director
    COVID Center of Excellence Satellite-Ansonia 
    Mount Sinai Health 
    New York, New York

    Rasika Karnik, MS, MD
    Assistant Professor
    Division of Primary Care
    Department of Internal Medicine
    University of Chicago
    Medical Director
    Post-COVID Recovery Clinic
    Chicago, Illinois

    Renslow Sherer, MD
    Director
    International HIV Training Center
    Professor of Medicine
    Section of Infectious Diseases and Global Health
    Department of Medicine
    University of Chicago
    Chicago, Illinois

    Joseph Torrisi, PharmD, BCIDP
    Clinical Pharmacy Specialist
    Infectious Diseases 
    Pharmacy
    Grady Health System
    Atlanta, Georgia

    Link to slides: 
    https://bit.ly/3hXMgId

    Link to full program: 
    https://bit.ly/3G271KL

    Will New COVID-19 Vaccines Affect Risk Stratification?

    Will New COVID-19 Vaccines Affect Risk Stratification?

    Fernando Carnavali, MD; Renslow Sherer, MD; and Joseph Torrisi, PharmD, BCIDP, discuss how new COVID-19 vaccines may affect risk stratification, including:

    • Omicron-specific vaccine
    • Role of vaccination in risk stratification

    Presenters:

    Fernando Carnavali, MD
    Associate Professor of Medicine
    Division Chief
    General Internal Medicine
    Department of Medicine
    Site Director 
    COVID Center of Excellence Satellite-Ansonia
    Mount Sinai Health System
    New York, New York

    Renslow Sherer, MD
    Director
    International HIV Training Center
    Professor of Medicine
    Section of Infectious Diseases and Global Health
    Department of Medicine
    University of Chicago
    Chicago, Illinois

    Joseph Torrisi, PharmD, BCIDP
    Clinical Pharmacy Specialist
    Infectious Diseases
    Pharmacy
    Grady Health System
    Atlanta, Georgia

    Link to slides:
    https://bit.ly/3WDYeFK

    Link to full program: 
    https://bit.ly/3WJdIbs

    COVID-19: Outpatient Therapeutic Updates

    COVID-19: Outpatient Therapeutic Updates

    In this episode, Sharon R. Lewin, AO, FRACP, PhD, FAHMS, discusses:  

    Principles for antiviral agent use in nonhospitalized patients

    • Preferred and alternative treatment options
    • Treatment prioritization when there are logistical or supply constraints

    Outpatient remdesivir use

    • PINETREE data (adult patients)
    • CARAVAN data (pediatric patients)
    • FDA approval and treatment candidacy

    Therapeutic updates

    • Ivermectin and the TOGETHER study
    • Monoclonal antibody use during current omicron era

    Presenter:  

    Sharon R. Lewin, AO, FRACP, PhD, FAHMSZ
    Director, The Peter Doherty Institute for Infection and Immunity
    Professor of Infectious Diseases
    University of Melbourne
    Consultant Infectious Diseases Physician
    Alfred Hospital and Royal Melbourne Hospital
    Melbourne, Australia

    Review the downloadable slideset at:
    https://bit.ly/3FXc90w

     

    Omicron Variant: Effects on Treatments for COVID-19

    Omicron Variant: Effects on Treatments for COVID-19

    The SARS-CoV-2 omicron variant has affected which of our COVID-19 treatment strategies are currently effective, with some expected to maintain their efficacy and some expected to lose their efficacy. In this episode, Arthur Kim, MD, discusses the effects of the SARS-CoV-2 omicron variant on many of the COVID-19 approved, authorized, and investigational treatment options, including:

    • Direct-acting, small-molecule antiviral agents such as   molnupiravir, nirmatrelvir + ritonavir, and remdesivir
    • Monoclonal antibody treatments such as bamlanivimab + etesevimab, casirivimab + imdevimab, cilgavimab + tixagevimab, regdanvimab, and sotrovimab

    Presenter:

    Arthur Kim, MD
    Associate Professor
    Department of Medicine
    Harvard Medical School
    Director, Viral Hepatitis Clinic
    Division of Infectious Diseases
    Massachusetts General Hospital
    Boston, Massachusetts

    Review the downloadable slidesets at:
    https://bit.ly/3FXc90w
    https://bit.ly/32tp2BT

    Link to full program: 
    https://bit.ly/3Ix8uZg

    Episode 67- What options exist for outpatient COVID treatment?

    Episode 67- What options exist for outpatient COVID treatment?

    What are these new oral antiviral agents for COVID and how well do they work? We answer these questions and a few more this week.

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    References:
    All references for Episode 67 are found on my Read by QxMD collection

    Disclaimer: 
    The information contained within the  ER-Rx podcast episodes, errxpodcast.com, and the @errxpodcast Instagram page is for informational/ educational purposes only, is not meant to replace professional medical judgement, and does not constitute a provider-patient relationship between you and the authors. Information contained herein may be accidentally inaccurate, incomplete, or outdated, and users are to use caution,  seek medical advice from a licensed physician, and consult available resources prior to any medical decision making. The contributors of the ER-Rx podcast are not affiliated with, nor do they speak on behalf of,  any medical institutions, educational facilities, or other healthcare programs.


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    Disclaimer:

    The information contained within the ER-Rx podcast episodes, errxpodcast.com, and the @errxpodcast Instagram page is for informational/ educational purposes only, is not meant to replace professional medical judgement, and does not constitute a provider-patient relationship between you and the authors. Information contained herein may be accidentally inaccurate, incomplete, or outdated, and users are to use caution, seek medical advice from a licensed physician, and consult available resources prior to any medical decision making. The contributors of the ER-Rx podcast are not affiliated with, nor do they speak on behalf of, any medical institutions, educational facilities, or other healthcare programs.

    Is the Juice Worth the Squeeze?

    S02E39 No Longer Vaxxed vs Unvaxxed

    S02E39 No Longer Vaxxed vs Unvaxxed

    John delivers a tribute to Justice Centre lawyer Brandon Langhjelm (1981-2021), to whom we dedicate this podcast. Then we discuss the hatred of the vaccinated against the unvaccinated. But there are signs of hope, as more and more vaxxed people take a stand against medical passports and mandates. We are beginning to see a realignment in the debate, away from “vaxxed versus unvaxxed” and instead toward  debate about tyranny versus human agency.

    Justice Centre, Nov 8, 2021: Tribute to Brandon Langhjelm 1981-2021

    The Post Millennial, Nov 11, 2021: Gene Simmons has harsh words for unvaccinated Americans, calling them 'the enemy'

    Daily Mail, Sep 5, 2021: Israel is planning to administer FOURTH Covid shot which could be adjusted to fight new variants as country battles wave of infections despite hugely successful vaccine roll-out

    IB Times, Aug 5, 2021: Fully Vaccinated Carnival Cruise Prompts Policy Changes After 'Small Number' Of Passengers Infected With COVID

    Gateway Pundit, May 12, 2021: Dr. Cole on Covid Jabs: "We've Seen More Deaths From This Shot Than All Vaccines in the Last 20 Years Combined"

    Citizen's Free Press, Nov 12, 2021: Young Cardiologist dies in sleep two weeks after getting Booster Vaccine

    CBC, Nov 9, 2021: Saint John cardiologist and 'inspiring spirit' dies suddenly

    Calgary Herald on Youtube, Sep 27, 2021: NDP calls for door to door vaccination campaign

    Newsmax, Oct 27, 2021: Bongino Off Radio This Week Over Vaccine Mandate

    Link to Tim Moen's Okotoks speech not found. Here's his Youtube page

    en-volve, Nov 10, 2021: Austrian Brothel Is Offering Free Sex If You Get Vaccinated

    Greencrow As The Crow Flies, Nov 9, 2021: Cpl. Daniel Bulford Speaks in Toronto

    BPR, Nov 4, 2021: Timely new Pfizer ad featuring ‘superhero’ kids sparks fierce debate

    James Kunstler, Nov 12, 2021: The Recognition

    CBC, Nov 10, 2021: Alberta rolls out its first outpatient COVID-19 treatment as experts warn it's not a vaccine substitute

    The Guardian, Nov 12, 2021: Netherlands imposes lockdown measures as Covid cases hit new high

    Theme Music "Carpay Diem" by Dave Stevens

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    The Monoclonal Antibodies Strike Back: New Data on Their Use in COVID-19

    The Monoclonal Antibodies Strike Back: New Data on Their Use in COVID-19

    In this podcast episode, Sharon R. Lewin, AO, FRACP, PhD, FAHMS, and Arthur Kim, MD, discuss data on the potential use of monoclonal antibodies (mAb) for the prevention and treatment of COVID-19, including:

    • Rationale for use of mAb
    • Potential for resistance to mAb
    • Single vs combination therapy with mAb
    • Challenges in implementation of mAb as treatment or prevention
    • Bamlanivimab
    • Sotrovimab
    • Casirivimab plus imdevimab

    Link to full program, including downloadable slidesets:  https://bit.ly/3zVTwYW

    Presenters: 

    Sharon R. Lewin, AO, FRACP, PhD, FAHMS
    Director, The Peter Doherty Institute for Infection and Immunity
    Professor of Infectious Diseases
    Faculty Medicine Dentistry and Health Sciences
    University of Melbourne and Royal Melbourne Hospital
    Consultant Infectious Diseases Physician
    Department of Infectious Diseases
    Royal Melbourne Hospital and Alfred Hospital
    Melbourne, Australia

    Arthur Kim, MD
    Associate Professor
    Department of Medicine
    Harvard Medical School
    Director, Viral Hepatitis Clinic
    Division of Infectious Diseases
    Massachusetts General Hospital
    Boston, Massachusetts

    Sharon R. Lewin, AO, FRACP, PhD, FAHMS, has disclosed that she has received consulting fees from AbbVie, Gilead Sciences, and ViiV Healthcare; funds for research support from Leidos; and other financial or material support from Gilead Sciences, Merck, and ViiV Healthcare.

    Arthur Kim, MD, has disclosed that he has served on the drug and safety monitoring board for Kintor.

    Expert Answers to Questions on Contemporary Management of Multiple Myeloma

    Expert Answers to Questions on Contemporary Management of Multiple Myeloma

    In this episode,  Shaji K. Kumar, MD; Thomas G. Martin, MD; Philippe Moreau, MD; S. Vincent Rajkumar, MD, and Jesús F. San-Miguel, MD, PhD, answer audience questions from a recent Clinical Care Options live webinar on managing multiple myeloma. Topics include:

    • Approaches for managing smoldering multiple myeloma
    • Insights on new strategies for managing newly diagnosed multiple myeloma
    • Incorporating newly approved agents in the frontline and early relapse setting
    • Choosing and sequencing BCMA-targeted therapies
    • Managing patients with refractory multiple myeloma

    Presenters:

    Shaji K. Kumar, MD
    Mark and Judy Mullins Professor of Hematological Malignancies
    Chair, Myeloma Amyloidosis Dysproteinemia Group
    Consultant, Division of Hematology
    Mayo Clinic
    Rochester, Minnesota

    Thomas G. Martin, MD
    Clinical Professor of Medicine
    Associate Director, Myeloma Program
    University of California, San Francisco Medical Center
    San Francisco, California

    Philippe Moreau, MD
    Professor of Clinical Hematology
    Head, Hematology Department
    University Hospital Hôtel-Dieu
    Nantes, France

    S. Vincent Rajkumar, MD
    Edward W. and Betty Knight Scripps Professor of Medicine
    Mayo Clinic
    Rochester, Minnesota

    Jesús F. San-Miguel, MD, PhD
    Director of Clinical and Translational Medicine
    Universidad de Navarra
    Pamplona, Spain

    Supported by educational grants from Amgen, Bristol-Myers Squibb, GlaxoSmithKline, Karyopharm and Oncopeptides.

    Link to full program, including downloadable slidesets and expert commentaries:
    https://bit.ly/39MWNid

     

    Interleukin 5: The Lancet Respiratory Medicine: March 23, 2015

    Interleukin 5: The Lancet Respiratory Medicine: March 23, 2015

    Targeting interleukin 5 for eosinophilic asthma – discussion with Jean Bousquet and Richard Lane.

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    The Lancet Oncology: March 01, 2011

    The Lancet Oncology: March 01, 2011

    March issue highlights, including new data from the HERA trial about long-term efficacy of herceptin for early breast cancer.

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    The Lancet Oncology: March 01, 2010

    The Lancet Oncology: March 01, 2010

    March issue highlights, including hypofractionated radiotherapy for early breast cancer.

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