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    pbc

    Explore " pbc" with insightful episodes like "Habrá tiro Mexicano en las vegas", "VENADO LOPEZ POR LA CONSOLIDACION!", "Selected FXR Agonist PBC Studies: Conference Coverage of AASLD", "Investigational PPAR-delta Agonist for PBC Treatment and Race-Based Considerations for PBC Diagnosis: Conference Coverage of AASLD" and "Investigational Dual PPAR Agonist, FXR Agonist With Fibrate, and Hyperlipidemia in People With PBC: Conference Coverage of AASLD" from podcasts like ""De Campana a Campana", "De Campana a Campana", "CCO Infectious Disease Podcast", "CCO Infectious Disease Podcast" and "CCO Infectious Disease Podcast"" and more!

    Episodes (100)

    Selected FXR Agonist PBC Studies: Conference Coverage of AASLD

    Selected FXR Agonist PBC Studies: Conference Coverage of AASLD

    During the 2023 American Association for the Study of Liver Diseases conference, exciting and important results from many primary biliary cholangitis (PBC) clinical trials were reported, including 3 late-breaking studies on the PPAR-δ agonist seladelpar, the dual PPAR agonist elafibranor, and the combination of the FXR agonist obeticholic acid and a fibrate.

    In this episode, Kris V. Kowdley MD, FAASLD, FACP, FACG, discusses topline results from several of these studies and more, including: 

    • A combination of 3 studies—HEROES, COBALT, and COBALT EC—that evaluated the real-world effectiveness and safety of second-line therapy in PBC where OCA was added to the treatment regimen of people with PBC with an incomplete response to ursodeoxycholic acid 
    • Lessons learned from a long-term outcomes study of people with PBC
    • Results from 2 phase II studies of obeticholic acid plus bezafibrate in people with PBC who did not respond to or were intolerant of ursodeoxycholic acid

    Presenter:

    Kris V. Kowdley MD, FAASLD, FACP, FACG
    Professor, Elson S. Floyd College of Medicine
    Washington State University
    Director, Liver Institute Northwest
    Seattle, Washington      

    Link to reviews of other PBC studies from AASLD 2023: 
    https://bit.ly/3RvXXEI

    Investigational PPAR-delta Agonist for PBC Treatment and Race-Based Considerations for PBC Diagnosis: Conference Coverage of AASLD

    Investigational PPAR-delta Agonist for PBC Treatment and Race-Based Considerations for PBC Diagnosis: Conference Coverage of AASLD

    During the 2023 American Association of the Study of Liver Diseases (AASLD) conference, exciting and important results from many primary biliary cholangitis (PBC) clinical trials were reported, including 3 late-breaking studies on the PPAR-delta agonist seladelpar, the dual PPAR agonist elafibranor, and the combination of the FXR agonist obeticholic acid and a fibrate.

    In this episode, Stuart C. Gordon, MD, FAASLD, discusses topline results from one of these late-breaking studies and more, including: 

    • A phase III study of an investigational PPAR-delta agonist (seladelpar) in people with PBC who had failed to respond to ursodeoxycholic acid
    • A study that explored racial differences as they relate to the presentation and diagnosis of PBC

    Presenter: 
    Stuart C. Gordon, MD, FAASLD
    Director of Hepatology
    Henry Ford Health System
    Professor of Medicine
    Wayne State University School of Medicine
    Detroit, Michigan

    Link to commentary:
    https://bit.ly/3GzRMt2

    Link to reviews of other PBC studies from AASLD 2023:
    https://bit.ly/3RvXXEI

    Investigational Dual PPAR Agonist, FXR Agonist With Fibrate, and Hyperlipidemia in People With PBC: Conference Coverage of AASLD

    Investigational Dual PPAR Agonist, FXR Agonist With Fibrate, and Hyperlipidemia in People With PBC: Conference Coverage of AASLD

    During the 2023 American Association of the Study of Liver Diseases (AASLD) conference, exciting and important results from many primary biliary cholangitis (PBC) clinical trials were reported, including 3 late-breaking studies on the PPAR-delta agonist seladelpar, the dual PPAR agonist elafibranor, and the combination of the FXR agonist obeticholic acid and a fibrate.

    In this episode, Marlyn J. Mayo, MD, discusses topline results from several of these studies and more, including: 

    • A phase III study of an investigational dual PPAR α/δ agonist (elafibranor) in people with PBC who did not respond to or were intolerant of ursodeoxycholic acid (UDCA)
    • A study that evaluated the effectiveness and safety of second-line therapy in PBC where obeticholic acid with or without a fibrate was added to the treatment regimen of people with PBC with an incomplete response to UDCA
    • A retrospective review of the rates of hyperlipidemia, atherosclerosis, and/or hepatic steatosis in patients with PBC

    Presenter: 

    Marlyn J. Mayo, MD
    Professor of Internal Medicine
    Division of Digestive & Liver Diseases
    UT Southwestern Medical Center
    Dallas, Texas

    Link to commentary:
    https://bit.ly/47PmGdc

    Link to reviews of other PBC studies from AASLD 2023: 
    https://bit.ly/3RvXXEI

    Episode 205 [Less Is More]

    Episode 205 [Less Is More]

    This is the 205th episode of the "Talk That Talk Show", hosted by Barry Holmes. Holmes delivers another quality episode, discussing sports, society and culture! 

    1. Shout Out To Touri & TK Placing 2nd In Tournament
    2. "Playing The Villain"
    3. Hat Hookup - New Era Buffalo
    4. Tank Davis Vs Ryan Garcia Fight Reaction
    5. NBA Playoffs - Inconsistent Refereeing
    6. Knicks Real Contenders? 


    Music: Zeshan Abbas (Vitamin Z)

    Support the show

    Boxing Week, Exciting Matchups Discussion and UFC!

    Boxing Week, Exciting Matchups Discussion and UFC!

    This past weekend's boxing matches were outstanding, and we discuss DAZN's highly entertaining event with fighters like Nikita Ababiy, Jessica McCaskill, MJ, Jesse Bam Rodriguez, and Hekkie Budler. We also discuss the UFC and their fantastic event this last weekend.

    Hekkie Budler vs Elwin Soto (1:50)
    DAZN' stacked Card (10:44)
    Canelo vs GGG Press tour reaction (53:59)
    UFC Apex Fight Night (59:24)

    https://www.instagram.com/thehbpod_/

    Ryan Garcia vs Emmanuel Tagoe, Gennady Golovkin vs Ryota Murata y Fundora vs Lubin En Español

    Ryan Garcia vs Emmanuel Tagoe, Gennady Golovkin vs Ryota Murata y Fundora vs Lubin En Español

    Otra vez tenemos peleas en diferentes canales todo el día! Dime sus opiniones! Quién va ganar?

    #Boxing #Boxeo #GarciaTagoe

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    ...

    Alexis Rocha vs Blair Cobbs Steals The Show; Berlanga vs Rolls Post Fight

    Alexis Rocha vs Blair Cobbs Steals The Show; Berlanga vs Rolls Post Fight

    Joined by the one and only A-Rod Without The Paycheck to talk about the fights that took place on March 19! Alexis Rocha vs Blair Cobbs was supposed to be the co-main for Vergil Ortiz Jr. vs Mckinson but due to the changes to Ortiz vs Mckinson, Rocha vs Cobbs became the main event! Turned out to be an exciting fight! Berlanga beat Rolls by decision which was not what his fan base expected.

    #Boxing #Boxeo

    https://www.youtube.com/@BoxingWithB

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    @ARODNOCHECK

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    ...

    Edgar Berlanga Contra Steve Rolls y Rocha Contra Cobbs En Espanol

    Edgar Berlanga Contra Steve Rolls y Rocha Contra Cobbs En Espanol

    Este fin de semana hay dos tarjetas, una en ESPN y otra en DAZN. Alexis Rocha vs Blair Cobbs en DAZN y Edgar Berlanga vs Steve Rolls en ESPN. Steve Rolls tiene una derrota y esa derrota era contra Gennady Golovkin!

    TWITTER:
    @BOXINGWITHB
    @ARODNOCHECK

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    https://www.youtube.com/@BoxingWithB

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    @ARODNOCHECK

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    ...

    Edgar Berlanga vs Steve Rolls and Alexis Rocha vs Blair Cobbs

    Edgar Berlanga vs Steve Rolls and Alexis Rocha vs Blair Cobbs

    March 19 we are set to tune in to 2 different fight cards on ESPN and on DAZN. We were expecting to see Vergil Ortiz jr vs Mckinson, but due to health reasons Vergil withdrew from the fight so we will now see Alexis Rocha vs undefeated fighter Blair Cobbs as the main event. On ESPN, Berlanga will take on Steve Rolls who has only one loss in his professional career but that one loss is to Gennady Golovkin.


    https://www.youtube.com/@BoxingWithB

    TWITTER:
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    @ARODNOCHECK

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    ...

    Chocolatito vs Martinez, Should Martinez stay at 115? Or Drop back down!?

    Chocolatito vs Martinez, Should Martinez stay at 115? Or Drop back down!?

    Roman Chocolatito Gonzalez is a living legend! He displayed his intelligence and patience in the ring against Julio Cesar Martinez! Martinez had some trouble making weight for the fight, but the fight was able to continue! Mauricio Lara vs Emilio Sanchez was a Mexican Style Fight! Definitely a great night of boxing!

    #boxing #boxeo #ChocolatitoMartinez 

    TWITTER:
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    @ARODNOCHECK

    IG: @BOXINGWITHB

    https://www.youtube.com/@BoxingWithB

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    @ARODNOCHECK

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    ...

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