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    AMA #8: Balancing Caffeine, Decision Fatigue & Social Isolation

    enJune 23, 2023
    What are the benefits of daily caffeine consumption?
    What should you avoid before bedtime regarding caffeine?
    How can one reduce caffeine intake safely?
    What symptoms indicate caffeine overuse or withdrawal?
    Why is it recommended to delay caffeine for young people?

    • Determining the Right Amount of Daily Caffeine ConsumptionCaffeine can enhance focus, mood, and athletic performance but may cause anxiety, sleep disturbances, and increased heart rate. Consider individual tolerance and avoid consuming close to bedtime for optimal benefits.

      For most adults, daily caffeine consumption can be beneficial if it doesn't cause anxiety or disrupt nighttime sleep. The Huberman Lab Podcast Premium channel supports research on mental health, physical health, and human performance, with every dollar generating a match from The Tiny Foundation. To determine if daily caffeine consumption is right for you, listen to the "Caffeine" episode on HubermanLab.com and consider the potential pros and cons. Key points include caffeine's ability to improve focus, mood, and athletic performance, but potential downsides like increased heart rate, jitters, and sleep disturbances. To minimize negative effects, avoid consuming caffeine within 8-12 hours of bedtime due to its long half-life. If you're interested in supporting the Huberman Lab's research and want access to premium content, visit HubermanLab.com/premium.

    • Caffeine's Effect on Sleep ArchitectureConsuming caffeine too close to bedtime can negatively impact sleep quality by reducing REM and slow wave sleep, while abstaining within 8-12 hours leads to better sleep architecture and increased energy.

      Consuming caffeine too close to bedtime can disrupt the architecture of your sleep, specifically reducing the amount of rapid eye movement sleep and slow wave sleep, leading to decreased alertness and cognitive abilities the next day. While it's understood that some people may still be able to fall asleep after consuming caffeine late in the day, consistently doing so can negatively impact sleep quality. Conversely, abstaining from caffeine within eight to 12 hours of bedtime can result in better sleep architecture and increased daytime energy and focus. Despite the widespread consumption of caffeine every day by 90% of adult humans, it's essential to be mindful of its potential impact on sleep, as the primary reason for daily consumption is often to feel more energized and focused at our baseline level.

    • Caffeine's Performance Enhancing Effects are Primarily Observed in Non-Regular UsersCaffeine can improve cognitive and physical performance, but benefits are mainly seen in those who abstain for a few days and then consume it, or for non-regular users.

      While caffeine can enhance cognitive and physical performance, the benefits are primarily observed when individuals abstain from caffeine for a few days and then consume it, or for those who don't regularly use caffeine. For the majority of the population who consume caffeine daily, there doesn't seem to be a significant net benefit in terms of cognitive or physical improvement, but there's also no major drawback, assuming one doesn't suffer from anxiety or lack of sleep due to caffeine consumption. Caffeine acts as a performance enhancer, but only in comparison to the non-caffeinated state. Most adults can tolerate caffeine doses between 100 to 300 milligrams, and the effects can vary depending on factors like body weight and regularity of consumption.

    • Caffeine intake varies based on beverage type and sizeConsuming coffee, yerba mate, or espresso provides caffeine, with intake ranging from 100 to 500 mg per serving. Best to drink in the morning for energy, avoid afternoon crashes, and for cognitive benefits, consider abstaining for a few days then consuming regularly.

      The type and amount of coffee or other caffeinated beverages consumed can determine caffeine intake, which ranges from 100 to 500 milligrams for a six to eight ounce serving. Regular sources of caffeine for most people include coffee, yerba mate, and espresso. For optimal energy levels, it's recommended to drink caffeine in the morning, preferably 90 minutes after waking, to avoid an afternoon crash. For those seeking enhanced cognitive effects, abstaining from caffeine for several days can lead to withdrawal symptoms, but regular consumption can increase dopamine receptors. Overall, moderate caffeine consumption for most adults is generally considered safe.

    • Caffeine's Effects on Mood and EnergyCaffeine can boost mood and energy by blocking adenosine receptors and increasing dopamine production. However, it's essential to consider individual tolerance and potential risks, especially for young people.

      Caffeine can have both mood-elevating and energy-boosting effects by blocking adenosine receptors and increasing dopamine production. However, not everyone can tolerate caffeine, and some people should avoid it due to sensitivity. As for children and adolescents, it's best to avoid caffeine consumption due to the developing brain's sensitivity and the lack of evidence supporting potential harms, such as stunted growth or osteoporosis. For older teenagers and young adults, caffeine consumption may be less risky as more brain development has already occurred. Overall, it's essential to consider individual tolerance and potential risks when deciding on daily caffeine consumption, especially for young people.

    • Limiting caffeine intake during adolescence benefits brain healthAvoiding caffeine during adolescence can improve brain health by preventing excessive neurochemicals and promoting better sleep quality, appetite, and reduced anxiety. However, clean sources like coffee or tea are recommended if consumed.

      Limiting caffeine intake, especially during adolescence and teenage years, can have significant advantages for brain health. Caffeine, found in energy drinks, sodas, and coffee, can negatively impact the developing brain by introducing excessive neurochemicals. Companies add ingredients like theanine to reduce the jitters and anxiety caused by caffeine, enabling consumers to continue consuming more. However, daily caffeine consumption can lead to poor sleep quality, lack of appetite, and anxiety. Personal experiences suggest that abstaining from caffeine can improve mindfulness and meditation practices but may result in lethargy and decreased motivation. It's recommended to avoid caffeine intake until 18 years old, but if consumed, it's essential to understand the ingredients and their potential long-term effects. Opting for clean sources like coffee or tea is recommended.

    • Reducing Caffeine Intake GraduallyInstead of quitting caffeine cold turkey, gradually cut intake in half and take a few days off to minimize withdrawal symptoms

      If you're experiencing the classic symptoms of caffeine overuse and withdrawal, but aren't necessarily abusing caffeine, there are ways to reduce your intake and minimize the withdrawal symptoms. Instead of quitting cold turkey, consider cutting your caffeine intake in half for a few days, then taking a couple of days off completely. This approach allows you to still enjoy the performance-enhancing effects of caffeine while reducing your dependence. By following this method, you can avoid the unpleasant symptoms of withdrawal and maintain a healthier relationship with caffeine.

    • Maintain a consistent caffeine baseline with occasional increasesRegularly reduce caffeine intake to a half dose as normal, increase occasionally for energy, mitigate crashes with sunlight and movement, avoid quantitative approach, recognize potential for anxiety and withdrawal, and consider delaying intake for young people.

      Maintaining a consistent baseline of caffeine intake with occasional increases for added energy is a healthier approach than setting a new higher baseline every day. This means reducing your daily caffeine intake to a half dose as your new normal, and only increasing it occasionally when needed. It's important to recognize that every time you significantly increase your caffeine intake above your baseline, you will experience a boost in energy followed by a crash. To mitigate the negative effects of this crash, try getting outside for some sunlight and movement. Avoid becoming too quantitative about your caffeine intake, as it's difficult to measure exact amounts, but do understand the contour of how caffeine works and the potential for anxiety and withdrawal effects. Lastly, if you're a young person, it's recommended to delay caffeine intake altogether or until you're older.

    • Join Huberman Lab Premium for Exclusive Content and Fund ResearchSupport Huberman Lab with a monthly or yearly membership to gain access to premium content, transcripts, and contribute to mental health, physical health, and performance research, with donations being matched dollar-for-dollar.

      By becoming a member of the Huberman Lab premium channel, you'll not only gain access to in-depth answers to your burning questions through Ask Me Anything sessions, but you'll also be directly contributing to funding valuable research focused on mental health, physical health, and performance for human beings. Your support will be matched dollar-for-dollar by The Tiny Foundation, effectively doubling the impact of your contribution. By signing up for $10 per month or $100 per year at HubermanLab.com/premium, you'll receive exclusive premium content and transcripts, as well as the satisfaction of contributing to scientific advancements.

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    AMA #18: Cold Therapy Advice, Skin Health Tips, Motivation, Learning Strategies & More

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    Welcome to a special edition of the 18th Ask Me Anything (AMA) episode, part of Huberman Lab Premium. This episode is a recording of the live stream AMA, exclusive to our Premium members. We've decided to make the full-length version available to everyone, including non-members of Huberman Lab Premium. Huberman Lab Premium was launched for two main reasons. First, it was launched in order to raise support for the main Huberman Lab podcast — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation and other donors. If you're not yet a member but enjoyed this full-length livestream AMA, we invite you to join Huberman Lab Premium. By subscribing, you'll gain access to exclusive benefits including our regular monthly full-length AMA episodes, AMA transcripts, podcast episode transcripts, early access to live events and more. Additionally, a significant portion of your membership proceeds contributes to advancing human scientific research. You can learn more about the research we were able to support in our Annual Letter 2023. If you're a Huberman Lab Premium member, you can access the transcript for this AMA episode here. Timestamps 00:00 Introduction & Announcements 00:15 Supporting Mental & Physical Health Research 01:56 Exciting New Research Initiatives 03:39 Skin Health & Appearance 14:46 Cold Therapy Benefits & Guidelines 21:18 Self-Motivation Strategies 27:05 Understanding REM Sleep 28:45 Morning Routine: Exercise & Cold Exposure 29:17 The Importance of REM Sleep 29:49 Non-Sleep Deep Rest (NSDR) Protocols 31:27 REM Sleep Rebound & Compensation 32:55 Impactful School Strategies for Learning 34:19 Meditation & Micro Gaps in Learning 39:13 Physical Activity & Learning 41:01 Exploring Shilajit & Testosterone 47:51 Writing Process & Overcoming Obstacles 51:32 Addiction & Recovery Resources 53:47 Closing Remarks & Gratitude Disclaimer & Disclosures
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    Dr. Peter Attia: Supplements for Longevity & Their Efficacy

    Dr. Peter Attia: Supplements for Longevity & Their Efficacy
    In this episode, my guest is Dr. Peter Attia, M.D., a Stanford and Johns Hopkins School of Medicine-trained physician expert in improving human healthspan and lifespan. Dr. Attia is also the host of The Drive podcast and author of the best-selling book Outlive.  We discuss the NAD pathway in human cells and its possible links to aging and health. We evaluate how supplementation can augment molecules in the NAD pathway; we compare NAD, NMN, and NR, different routes of administration, their safety, and bioavailability. Then, we discuss the broader research and clinical literature on longevity to decide if supplementation with NAD, NR, NMN, rapamycin, or resveratrol can indeed extend lifespan.  Finally, we each describe our supplement regimens and compare the role of supplementation to behaviors such as sleep, nutrition, and exercise for longevity. We also discuss whether tests of biological age are true indicators of aging and whether normal radiation levels increase cancer risk.  Listeners of this episode will learn if supplements purported to improve lifespan show any efficacy and the behaviors and other factors that can prevent disease and extend lifespan. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/huberman Levels: https://levels.link/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps 00:00:00 Dr. Peter Attia, NAD Pathway 00:02:31 Sponsors: LMNT, Levels & Eight Sleep 00:06:38 Categories of Longevity Approaches 00:17:22 Peter’s Supplements; Rapamycin & Research Data 00:25:01 NAD Pathway: Energy & DNA Repair; Knock-Out & Knock-In, Klotho 00:30:35 Sponsor: AG1 00:32:25 Yeast, Sirtuins, Caloric Restriction & Lifespan 00:38:56 Sirtuins, Transgenic Mice, Gender & Lifespan 00:43:42 DNA Repair, Sirtuins, Cancer; Resveratrol 00:53:31 Perform with Dr. Andy Galpin Podcast 00:54:18 NAD & NADH, Reactive Oxygen Species (ROS), Mitochondrial Health 01:02:17 NAD vs NR vs NMN Supplementation; IV & Oral Routes 01:11:33 NR vs. NMN, Doses, Side Effects; Interventions Testing Program 01:17:43 Fatty Liver Disease & NR; NMN & Glucose; Clinical Significance 01:25:17 Safety & FDA, NMN & NR Supplementation; Skin Cancer Benefits 01:30:38 Longevity, NR & NMN Supplementation, Inflammation 01:41:00 Rapamycin & Immune Function 01:44:37 Biological Aging Tests, Chronologic & Biologic Age; Vigor  01:55:24 Radiation & Cancer Risk 01:58:12 Tool: Self-Care in 50s-70s & Aging; Energy Decline 02:07:12 Tool: Exercise Timing & Energy Levels 02:11:22 Peter’s Supplements 02:18:46 Andrew’s Supplements 02:24:34 Tool: Supplement Use vs. Critical Behaviors; Titanic Analogy  02:26:52 NAD Pathway Supplementation for Longevity? 02:28:52 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Social Media, Neural Network Newsletter Disclaimer
    Huberman Lab
    enJuly 29, 2024

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    Order Dr Chatterjee's new book Happy Mind, Happy Life:

    UK version: https://amzn.to/304opgJ

    US & Canada version: https://amzn.to/3DRxjgp 

    Show notes available at https://drchatterjee.com/250


    Support the podcast and enjoy Ad-Free episodes. Try FREE for 7 days on Apple Podcasts https://apple.co/3oAKmxi. For other podcast platforms go to https://fblm.supercast.com.


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    Hosted on Acast. See acast.com/privacy for more information.


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