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    E3: Modern Cold War between US & China, economic recovery, potential mass migration out of San Francisco, pandemic politicization & more with David Sacks & David Friedberg

    enMay 21, 2020

    Podcast Summary

    • Adapting to remote work during quarantineDavid Sacks shares how his firm has remained collaborative and productive using tools like Zoom and Yammer, and even closed deals remotely. Despite the challenges, they've proven they can be effective working from home.

      Despite the challenges of the quarantine, business continues to thrive through remote work. David Sacks, a successful entrepreneur with a background at PayPal, Yammer, and Kraft Venture Capital, shared how his firm has adapted to the new normal. They've remained collaborative using tools like Zoom and Yammer, and have even closed several deals remotely. Sacks also mentioned that while they will eventually return to their physical office, they've proven they can be productive working from home. The mental health of those in quarantine was also discussed, with Sacks sharing his experience of living in an undisclosed Mexican location during the pandemic. He noted that while it's sad to see the deserted tourist city, safety measures are being taken and it's been a good experience overall. Overall, the conversation highlighted the resilience of businesses and individuals in the face of unprecedented circumstances.

    • The pandemic's impact on mental health and social interactionThe pandemic has presented unique challenges for mental health and social interaction, with some finding new routines helpful while others struggle. Businesses have also been affected differently, with food businesses seeing success and hardware/lab companies facing interruptions.

      The ongoing shelter-in-place situation is challenging for many people, particularly those who are extroverts and rely on social interaction. The lack of a consistent daily routine has been a major issue for some, leading to mental health concerns and sleep issues. However, creating a new routine and finding ways to work outside of the home have helped improve mental health for others. The business landscape is also varied, with hardware and lab companies facing significant interruptions, while food businesses have seen success. Overall, the pandemic has highlighted the importance of social interaction and the need for a return to offices once it's safe to do so. Chamath Palihapitiya, who runs a startup studio, shared that while some of their hardware and lab companies have faced pauses in operations, their food businesses have thrived. He also reflected on their earlier conversation about the pandemic and noted that while some predictions have held true, others have been surprising. For instance, he is more optimistic about the long-term impact of the pandemic on human health and food supply chains, but more pessimistic about the long-term impact on social interaction and office culture.

    • Politicization of COVID-19 response in USDespite disagreements over lockdowns and mask-wearing, speakers expressed optimism for control within 2 years through therapeutics and vaccines, but lamented the politicized response and potential economic depression.

      The COVID-19 pandemic response has become heavily politicized in the United States, leading to a divide between those who prioritize lockdowns and mask-wearing, and those who prefer to return to work. This politicization has made it difficult for a middle ground approach to gain traction. Another key takeaway is that the fatality rate of COVID-19, initially reported to be around 6%, has been found to be overstated due to the lack of consideration of asymptomatic and mild cases. Additionally, the speakers expressed optimism that the pandemic will be under control within two years through therapeutics and vaccines, but expressed disappointment in the lack of common sense procedures and the politicization of the response. The speakers also mentioned the potential for a depression due to the prolonged lockdowns and economic downturn. Overall, the conversation highlighted the importance of finding a balanced approach to managing the pandemic and the economy, while acknowledging the challenges presented by the politicized nature of the response.

    • COVID-19's Actual Fatality Rate and the Importance of Widescale TestingThe IFR of COVID-19 is likely around 0.5%, much lower than initial estimates. Widescale testing is crucial to accurately determine the baseline and understand the impact of asymptomatic spread.

      The infection fatality rate (IFR) of COVID-19 is likely closer to 0.5% than 5%, and wide-scale population testing is crucial to determine the accurate baseline. Young, healthy individuals under 60 with no preexisting conditions have a significantly lower risk of severe outcomes. Widescale mask usage can effectively control the virus without requiring lockdowns. Early on, it was clear that COVID-19 had a low fatality rate, but the extent of asymptomatic spread was underestimated. Despite these miscalculations, the importance of asymptomatic spread and the effectiveness of masks have become increasingly clear.

    • Desire for freedom hinders lockdown effectivenessDespite strict lockdown measures, people's unwillingness to comply fully and the belief in returning to normalcy have hindered their effectiveness. A nuanced approach with masks, temperature checks, and other safety measures is necessary.

      The lockdown measures implemented in the United States to curb the spread of COVID-19 have been less effective than expected due to people's desire for freedom and unwillingness to comply fully. The speaker observed this during a visit to Berkeley, where frat parties were taking place without masks or social distancing. The belief that a strict lockdown would stop the virus in its tracks has proven to be an overestimation. Instead, a nuanced approach that includes masks, temperature checks, and other safety measures is necessary. The speaker also believes that people will eventually grow tired of the lockdown and return to work and normal life, regardless of the orders in place. The stock market's seemingly inexplicable v-shaped recovery, despite the ongoing pandemic, may be due to this sentiment of returning to normalcy and the belief that the economy will bounce back sooner than expected.

    • Stock Market Booms While Economy StrugglesThe stock market recovers faster than the economy due to the Fed's interventions, but the real economy may take years to recover fully, with potential underemployment or unemployment beyond reported numbers.

      The economy is in a dire state, with millions of Americans unemployed, yet the stock market is buoyed by the Federal Reserve's money printing and interventions. The real economy is not recovering at the same pace as the equity market, with companies that deal in physical goods struggling while software businesses thrive. The recovery may take 2 to 3 years, but the true unemployment numbers may be higher due to people leaving the workforce. The economy's current state is divorced from the financial markets, and it's uncertain how long it will take to create the necessary jobs for a full recovery.

    • The COVID-19 pandemic's economic and societal impacts are complexDespite labor shortages from some leaving workforce, economic crises and waves of defaults are concerns. Population density and individual behaviors impact virus spread, with densely populated areas experiencing faster spread.

      The economic and societal impacts of the COVID-19 pandemic are complex and far-reaching. While some people are leaving the workforce and may not return, creating a labor shortage, there are also concerns about upcoming economic crises due to the ongoing pandemic and potential waves of defaults. The spread of the virus is influenced by factors such as population density and individual behaviors, with confined spaces like subways being particularly risky. It's important to remember that these factors exist on a probabilistic spectrum, and different areas will experience the pandemic differently. The situation in New York City, with its high population density and crowded subways, led to a rapid spread of the virus. However, cities like Dallas, Houston, and San Diego are less densely populated and are more likely to experience a slower spread. Overall, the next few years will be critical in navigating the ongoing economic and societal challenges posed by the pandemic.

    • Political Charge in US COVID-19 Response: Masks, Lockdowns, and Cultural WarThe politically charged COVID-19 response in the US has resulted in a cultural war between mask wearers and non-mask wearers, with inconsistent messaging and a focus on political implications over health crisis. This divide could impact the November election, with frustration among voters due to lack of unity and political courage.

      The COVID-19 pandemic response in the United States has become politically charged, with Americans prioritizing personal freedoms over public health measures like masks and lockdowns. This divide between mask wearers and non-mask wearers has turned into a cultural war between the left and the right. The communication of guidelines has been confusing, with inconsistent messaging from governors and a focus on the political implications of the response rather than the health crisis itself. The lack of unity and political courage to make decisions independently of political persuasion could result in frustration among voters, potentially leading to the re-election of President Trump in November. The unwillingness to end lockdowns and the perceived infringement on personal freedoms has become a significant issue for many Americans, overshadowing the incompetence of the initial COVID-19 response.

    • Hydroxychloroquine Debate: Political Issue vs. Clinical EvidenceValid concerns over side effects and lack of clear data fuel political debate on hydroxychloroquine use as a COVID-19 treatment. Careful consideration and patient-by-patient approach needed.

      The debate surrounding the use of hydroxychloroquine as a COVID-19 treatment has become a political issue, with valid concerns over potential side effects and the lack of clear clinical trial data fueling disagreement. The drug, which can inhibit energy production in certain cells and potentially cause heart and vision issues, requires careful consideration and a patient-by-patient approach. Looking ahead, the world may see permanent changes as a result of the pandemic, such as increased remote work and potential relocation trends for older populations, depending on whether the virus becomes endemic.

    • Impact of remote work on expensive cities like San FranciscoRemote work could lead to decreased demand for expensive housing in cities, increased efficiency, profitability, and better work-life balance for employees.

      The shift to remote work could significantly impact cities like San Francisco, which have historically attracted residents due to their strong industry networks. If companies can operate efficiently and profitably with remote workers, they may cut costs by reducing office space and potentially relocating or hiring from anywhere in the world. This could lead to a decrease in demand for expensive housing in cities like San Francisco, and potentially break the area's network effect. On a positive note, remote work offers employees more flexibility, allowing them to live where they want and have more time for personal pursuits. Overall, the trend towards remote work has the potential to lead to increased efficiency, profitability, and a better work-life balance for many.

    • California Exodus: High Costs, Taxes, and Regulations Driving Businesses and Individuals AwayThe high cost of living, taxes, and regulations in California are causing a mass exodus of businesses and individuals, accelerated by the pandemic, and deregulation could lead to significant advancements in science and engineering, potentially eradicating all infectious diseases within the next 20 years.

      The high cost of living, taxes, and strict regulations in California are driving many businesses and individuals to consider leaving the state. This trend was evident even before the COVID-19 pandemic, but the pandemic has accelerated this trend as people reevaluate their living and work situations. The high-profile examples of Elon Musk selling his homes and moving Tesla out of California, and the political debates over lockdowns and small business regulations, illustrate this trend. Furthermore, the speaker believes that the deregulation of certain industries could lead to significant benefits and accelerate new outcomes, such as the eradication of all infectious diseases within the next 20 years. The speaker's strong belief is that the advancements in science and engineering are holding this goal back, and the removal of regulatory barriers could help bring these advancements to fruition.

    • Regulation and Innovation ChallengesExcessive regulation and inept bureaucracy hinder businesses and innovation, as seen with Tesla and other industries. The COVID-19 pandemic may lead to deregulation and new tech adoption. Geopolitical tensions between the US and China raise questions about the nature of the conflict and US standing.

      Excessive regulation and inept bureaucracy can significantly hinder businesses and innovation, as evidenced by the challenges faced by Tesla and the ongoing regulatory burden in various industries. The COVID-19 pandemic has further highlighted this issue and could potentially lead to deregulation and the adoption of new technologies. Additionally, geopolitically, the US-China relationship is becoming increasingly contentious, with China making strategic investments to challenge the US as the world's most powerful country. This situation raises questions about the nature of this conflict – political, ideological, or practical – and whether it's possible for all parties to agree on a resolution. Personally, some view this as a practical issue, while others see it as an ideological one. Regardless of perspective, the goal is to ensure that the US maintains its standing as the most important country in the world.

    • Speak out against human rights violations, engage or decouple with ChinaIndividuals and governments should uphold human rights, engage or decouple with China depending on strategic considerations, and employ alternative forms of punishment when legal means are limited.

      Individuals and governments should uphold human rights and speak out against human rights violations, such as torture and censorship of free speech. Additionally, there is a need for self-improvement in one's own country before engaging with others on human rights issues. Regarding China, there is a debate on whether engagement or decoupling is the better approach. Decoupling may be necessary for strategic reasons, especially in terms of essential products and national security. China's handling of the COVID-19 pandemic and the case of TikTok raise questions about their liability and the allowance of their platforms in other countries, respectively. However, practical considerations limit the ability to hold China accountable through legal means. Instead, other forms of "punishment" may be employed.

    • US-China economic interdependenceThe US can demand reciprocity in trade, reduce dependence on China for critical parts, and explore new methods of production to decouple from China, while preserving cultural elements and addressing America's own issues.

      The US cannot completely cut ties with China economically due to interdependence and the reality of China being a major source of production for the US. However, the US can demand more reciprocity in trade and focus on reducing dependence on China for critical parts of the supply chain and infrastructure. The speakers also emphasized the importance of addressing America's own issues and preserving unique cultural elements, rather than focusing solely on China's human rights record while continuing to trade with them. Additionally, there is a need to explore new methods of production through automation, 3D printing, and biomanufacturing to potentially decouple from China and shift the balance of power towards labor.

    • Potential benefits of increased production costs and immunity to coronavirusThe US could benefit from higher production costs leading to industry reinvention and global competitiveness, as well as potential herd immunity from previous coronavirus exposure

      The economy could benefit from increased production costs and inflation, as it could lead to the reinvention of industries and the creation of new, more efficient methods of production in the US. This could potentially help the country compete globally and reduce its reliance on imports. Additionally, a significant portion of the population may already have some level of immunity to the current coronavirus due to previous exposure to other coronaviruses, which could contribute to herd immunity and the eventual control of the pandemic. It's important to note that this doesn't mean individuals won't still get infected or spread the virus, but their immune response may help them recover more quickly. The discovery of this individual immunity is an important finding that could help inform public health strategies moving forward. Overall, the discussion highlighted the potential for the US to leverage its unique position in technology and innovation to overcome economic and health challenges.

    • Understanding the human response to coronavirus is a work in progressWe have a good understanding of the coronavirus itself but only around 40-30% of the human response and resulting symptoms are mapped out. It will take time to fully understand the complex relationship between the virus and the human body.

      While we have a good understanding of the coronavirus itself, our knowledge about how it affects individuals based on their genotype is limited. We are currently estimating that we have mapped out around 40-30% of the human response to the virus and the resulting symptoms. This is in contrast to viruses like HIV and Ebola, for which we have a better understanding after years of research. It's important to remember that we have a complete understanding of the virus itself, but the human response and resulting symptoms are still a mystery. We are making progress, but it will take time to fully understand the complex relationship between the virus and the human body. Stay informed and stay safe.

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    https://www.supremecourt.gov/opinions/23pdf/23-939_e2pg.pdf

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    https://www.macrotrends.net/stocks/charts/GME/gamestop/revenue

    https://www.wsj.com/finance/stocks/gamestop-burned-andrew-left-in-2021-hes-betting-against-the-stock-again-4377cecb

    https://www.nytimes.com/2022/05/18/business/melvin-capital-gamestop-short.html

    https://www.instagram.com/tim.naki/reels

    https://www.wsj.com/finance/regulation/new-texas-stock-exchange-takes-aim-at-new-yorks-dominance-e3b4d9ba

    https://listingcenter.nasdaq.com/assets/Board%20Diversity%20Disclosure%20Five%20Things.pdf

    https://www.bloomberg.com/news/articles/2024-06-05/why-is-apple-aapl-teaming-up-with-openai-both-companies-need-each-other

    https://x.com/leonsimons8/status/1793319395080520036

    Trump verdict, COVID Cover-up, Crypto Corner, Salesforce drops 20%, AI correction?

    Trump verdict, COVID Cover-up, Crypto Corner, Salesforce drops 20%, AI correction?

    (0:00) Bestie Intros: Jason's first show for his new production company

    (2:15) Why Sacks and Chamath are hosting a Trump fundraiser

    (18:40) House COVID investigation: findings, cover-up, what's next?

    (41:36) The Deep State Problem: unelected bureaucrats running three letter agencies for decades

    (53:04) Crypto Corner with Chamath

    (1:04:15) State of SaaS: Salesforce drops 20%, market teetering

    (1:20:10) Trump verdict: guilty on 34 counts of falsifying business records

    (1:37:36) Are we seeing an AI correction?

    Follow the besties:

    https://twitter.com/chamath

    https://twitter.com/Jason

    https://twitter.com/DavidSacks

    https://twitter.com/friedberg

    Follow on X:

    https://twitter.com/theallinpod

    Follow on Instagram:

    https://www.instagram.com/theallinpod

    Follow on TikTok:

    https://www.tiktok.com/@all_in_tok

    Follow on LinkedIn:

    https://www.linkedin.com/company/allinpod

    Intro Music Credit:

    https://rb.gy/tppkzl

    https://twitter.com/yung_spielburg

    Intro Video Credit:

    https://twitter.com/TheZachEffect

    Referenced in the show:

    https://oversight.house.gov/release/new-select-subcommittee-report-recommends-ecohealth-alliance-president-debarred-and-criminally-investigated-exposes-failures-in-nih-grant-procedures

    https://oversight.house.gov/release/hearing-wrap-up-nih-repeatedly-refutes-ecohealth-alliance-president-dr-peter-daszaks-testimony-tabak-testimony-reveals-federal-grant-procedures-in-need-of-serious-reform

    https://www.axios.com/2021/07/20/fauci-rand-paul-wuhan-institute

    https://oversight.house.gov/release/breaking-hhs-suspends-funding-and-proposes-formal-debarment-of-ecohealth-alliance-cites-evidence-from-covid-select-report

    https://oversight.house.gov/release/breaking-hhs-to-debar-dr-peter-daszak-president-of-ecohealth-alliance

    https://x.com/emilyakopp/status/1795482121739354552

    https://x.com/R_H_Ebright/status/1795454118594568312

    https://www.youtube.com/watch?v=jGxSlW0NrB4

    https://www.cidrap.umn.edu/dual-use-research/feds-lift-gain-function-research-pause-offer-guidance

    https://www.washingtonpost.com/opinions/a-flu-virus-risk-worth-taking/2011/12/30/gIQAM9sNRP_story.html

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484390

    https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30418-9/fulltext

    https://oversight.house.gov/release/new-covid-select-memo-details-allegations-of-wrongdoing-and-illegal-activity-by-dr-faucis-senior-scientific-advisor

    https://fiscaldata.treasury.gov/americas-finance-guide/national-deficit

    https://x.com/KatherineEban

    https://x.com/emilyakopp

    https://www.semafor.com/article/05/28/2024/a-dying-empire-led-by-bad-people-poll-finds-young-voters-despairing-over-us-politics

    https://www.youtube.com/watch?v=nvQTXAgtA6s

    https://s23.q4cdn.com/574569502/files/doc_financials/2025/q1/CRM-Q1-FY25-Earnings-Press-Release-w-financials.pdf

    https://www.investors.com/news/economy/federal-reserve-core-pce-inflation-gdp-q1-jobless-claims-sp-500

    https://www.nytimes.com/live/2024/05/30/nyregion/trump-trial-verdict

    https://www.google.com/finance/quote/DELL:NYSE

    https://www.bloomberg.com/news/articles/2024-05-30/us-gdp-grew-at-softer-pace-as-spending-inflation-marked-down

    Scarlett Johansson vs OpenAI, Nvidia's trillion-dollar problem, the "vibecession," plastic in our balls

    Scarlett Johansson vs OpenAI, Nvidia's trillion-dollar problem, the "vibecession," plastic in our balls

    (0:00) Bestie intros: Recapping "General AI Hospital"

    (2:46) Scarlett Johansson vs. OpenAI

    (14:37) OpenAI's novel off-boarding agreements, ex-employee equity problem, and safety team resignations

    (25:35) Nvidia crushes earnings again, but it faces a trillion-dollar problem

    (40:05) Understanding why economic sentiment is so negative among US citizens despite positive data

    (1:02:36) New study shows plastics in testicles

    Follow the besties:

    https://twitter.com/chamath

    https://twitter.com/Jason

    https://twitter.com/DavidSacks

    https://twitter.com/friedberg

    Follow on X:

    https://twitter.com/theallinpod

    Follow on Instagram:

    https://www.instagram.com/theallinpod

    Follow on TikTok:

    https://www.tiktok.com/@all_in_tok

    Follow on LinkedIn:

    https://www.linkedin.com/company/allinpod

    Intro Music Credit:

    https://rb.gy/tppkzl

    https://twitter.com/yung_spielburg

    Intro Video Credit:

    https://twitter.com/TheZachEffect

    Referenced in the show:

    https://x.com/BobbyAllyn/status/1792679435701014908

    https://x.com/sama/status/1790075827666796666

    https://openai.com/index/how-the-voices-for-chatgpt-were-chosen

    https://www.washingtonpost.com/technology/2024/05/22/openai-scarlett-johansson-chatgpt-ai-voice

    https://x.com/SydSteyerhart/status/1792981291266138531

    https://www.vox.com/future-perfect/351132/openai-vested-equity-nda-sam-altman-documents-employees

    https://x.com/sama/status/1791936857594581428

    https://x.com/ilyasut/status/1790517455628198322

    https://x.com/janleike/status/1790603862132596961

    https://x.com/janleike/status/1791498184671605209

    https://openai.com/index/openai-announces-leadership-transition

    https://nvidianews.nvidia.com/news/nvidia-announces-financial-results-for-first-quarter-fiscal-2025

    https://www.google.com/finance/quote/INTC:NASDAQ

    https://www.morningstar.com/stocks/nvidia-2023-vs-cisco-1999-will-history-repeat

    https://www.fool.com/investing/2024/03/06/is-nvidia-doomed-to-be-the-next-cisco-what-investo

    https://www.elitetrader.com/et/threads/nvidia-and-the-cautionary-tale-of-cisco-systems.379022

    https://chamath.substack.com/p/2023-annual-letter

    https://www.forbes.com/sites/theapothecary/2024/03/23/summers-inflation-reached-18-in-2022-using-the-governments-previous-formula

    https://www.theguardian.com/us-news/article/2024/may/22/poll-economy-recession-biden

    https://fred.stlouisfed.org/series/CCLACBW027SBOG

    https://x.com/KariLake/status/1792986501820850333

    https://www.stlouisfed.org/on-the-economy/2024/apr/how-big-mac-index-relates-overall-consumer-inflation

    https://www.google.com/finance/quote/MCD:NYSE

    https://www.wsj.com/economy/gdp-and-the-dow-are-up-but-what-about-american-well-being-87f90e6d

    https://www.consumerreports.org/health/food-contaminants/the-plastic-chemicals-hiding-in-your-food-a7358224781

    https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2605.2007.00837.x

    https://pubmed.ncbi.nlm.nih.gov/12708228

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7559247

    https://pubmed.ncbi.nlm.nih.gov/21524797

    https://academic.oup.com/toxsci/advance-article/doi/10.1093/toxsci/kfae060/7673133

    https://www.youtube.com/watch?v=o6yuYkfNh-k

    https://www.youtube.com/watch?v=EYQjShJxCtM

    https://www.youtube.com/watch?v=r_4jrMwvZ2A

    GPT-4o launches, Glue demo, Ohalo breakthrough, Druck's Argentina bet, did Google kill Perplexity?

    GPT-4o launches, Glue demo, Ohalo breakthrough, Druck's Argentina bet, did Google kill Perplexity?

    (0:00) Bestie Intros: Recapping Phil Hellmuth's birthday weekend

    (7:38) OpenAI launches GPT-4o: better, faster, cheaper

    (29:40) Sacks demos Glue: How AI unlocked his Slack killer

    (40:12) Friedberg walks through his major breakthrough at Ohalo

    (1:01:35) Stanley Druckenmiller bets on Argentina and Javier Milei: strategy, roadmap for the US

    (1:13:54) Jason's bet on Athena, how AI will change company building

    (1:22:21) Google launches AI summaries in search

    Follow the besties:

    https://twitter.com/chamath

    https://twitter.com/Jason

    https://twitter.com/DavidSacks

    https://twitter.com/friedberg

    Follow on X:

    https://twitter.com/theallinpod

    Follow on Instagram:

    https://www.instagram.com/theallinpod

    Follow on TikTok:

    https://www.tiktok.com/@all_in_tok

    Follow on LinkedIn:

    https://www.linkedin.com/company/allinpod

    Intro Music Credit:

    https://rb.gy/tppkzl

    https://twitter.com/yung_spielburg

    Intro Video Credit:

    https://twitter.com/TheZachEffect

    Referenced in the show:

    https://www.pokernews.com/news/2024/05/phil-hellmuth-60th-birthday-bash-las-vegas-45984.htm

    https://x.com/OpenAI/status/1790130703721521305

    https://x.com/OpenAI/status/1790089513387143469

    https://crfm.stanford.edu/helm/mmlu/v1.3.0/#

    https://www.businessinsider.com/inflection-implosion-chatgpt-stall-ai-consumer-chatbot-problem-2024-3

    https://www.opencompute.org

    https://glue.ai

    https://ragie.ai

    https://ohalo.com

    https://www.cnbc.com/2024/05/07/cnbc-exclusive-cnbc-transcript-billionaire-investor-stanley-druckenmiller-speaks-with-cnbcs-squawk-box-today.html

    https://www.forbes.com/sites/theapothecary/2024/03/23/summers-inflation-reached-18-in-2022-using-the-governments-previous-formula

    https://twitter.com/DavidSacks/status/1378034932006592512

    https://www.athenawow.com/jcal

    https://calacanis.substack.com/p/startup-productivity-in-the-age-of

    https://blog.google/products/search/generative-ai-google-search-may-2024

    https://www.youtube.com/watch?v=XEzRZ35urlk

    https://finance.yahoo.com/quote/GOOG

    https://startuptalky.com/apple-failed-products

    In conversation with Sam Altman

    In conversation with Sam Altman

    (0:00) Welcoming Sam Altman to the show!

    (2:28) What's next for OpenAI: GPT-5, open-source, reasoning, what an AI-powered iPhone competitor could look like, and more

    (21:56) How advanced agents will change the way we interface with apps

    (33:01) Fair use, creator rights, why OpenAI has stayed away from the music industry

    (42:02) AI regulation, UBI in a post-AI world

    (52:23) Sam breaks down how he was fired and re-hired, why he has no equity, dealmaking on behalf of OpenAI, and how he organizes the company

    (1:05:33) Post-interview recap

    (1:10:38) All-In Summit announcements, college protests

    (1:19:06) Signs of innovation dying at Apple: iPad ad, Buffett sells 100M+ shares, what's next?

    (1:29:41) Google unveils AlphaFold 3.0

    Follow Sam:

    https://twitter.com/sama

    Follow the besties:

    https://twitter.com/chamath

    https://twitter.com/Jason

    https://twitter.com/DavidSacks

    https://twitter.com/friedberg

    Follow on X:

    https://twitter.com/theallinpod

    Follow on Instagram:

    https://www.instagram.com/theallinpod

    Follow on TikTok:

    https://www.tiktok.com/@all_in_tok

    Follow on LinkedIn:

    https://www.linkedin.com/company/allinpod

    Intro Music Credit:

    https://rb.gy/tppkzl

    https://twitter.com/yung_spielburg

    Intro Video Credit:

    https://twitter.com/TheZachEffect

    Referenced in the show:

    https://twitter.com/EconomyApp/status/1622029832099082241

    https://sacra.com/c/openai

    https://twitter.com/tim_cook/status/1787864325258162239

    https://openai.com/index/introducing-the-model-spec

    https://twitter.com/SabriSun_Miller/status/1788298123434938738

    https://www.archives.gov/founding-docs/bill-of-rights-transcript

    https://twitter.com/ClayTravis/status/1788312545754825091

    https://www.inc.com/bill-murphy-jr/warren-buffett-just-sold-more-than-100-million-shares-of-apple-reason-why-is-eye-opening.html

    https://www.youtube.com/watch?v=snbTCWL6rxo

    https://www.digitimes.com/news/a20240506PD216/apple-ev-startup-genai.html

    https://www.theonion.com/fuck-everything-were-doing-five-blades-1819584036

    https://blog.google/technology/ai/google-deepmind-isomorphic-alphafold-3-ai-model

    In conversation with Sheryl Sandberg, plus open-source AI gene editing explained

    In conversation with Sheryl Sandberg, plus open-source AI gene editing explained

    (0:00) Welcoming Sheryl Sandberg and remembering Dave Goldberg

    (11:10) What led Sheryl to get involved with "Screams Before Silence"; reaction to sexual violence on and after 10/7

    (28:18) Paths forward, documentary decisions, involvement of women in protests

    (53:03) Post-interview debrief

    (59:45) Science Corner: Open-source AI gene editing with OpenCRISPR-1

    Follow Sheryl:

    https://twitter.com/sherylsandberg

    Watch Screams Before Silence:

    https://www.youtube.com/watch?v=zAr9oGSXgak&rco=1

    Follow the besties:

    https://twitter.com/chamath

    https://twitter.com/Jason

    https://twitter.com/DavidSacks

    https://twitter.com/friedberg

    Follow on X:

    https://twitter.com/theallinpod

    Follow on Instagram:

    https://www.instagram.com/theallinpod

    Follow on TikTok:

    https://www.tiktok.com/@all_in_tok

    Follow on LinkedIn:

    https://www.linkedin.com/company/allinpod

    Intro Music Credit:

    https://rb.gy/tppkzl

    https://twitter.com/yung_spielburg

    Intro Video Credit:

    https://twitter.com/TheZachEffect

    Referenced in the show:

    https://twitter.com/fakechamath

    https://www.youtube.com/watch?v=zAr9oGSXgak&rco=1

    https://www.cnn.com/2023/11/20/opinions/sheryl-sandberg-something-we-can-all-agree-on/index.html

    https://news.un.org/en/story/2024/03/1147477

    https://thegrayzone.com/2024/03/07/media-concocts-un-hamas-rape-report/amp/

    https://www.nytimes.com/2024/01/29/world/middleeast/israel-hamas-sexual-violence-un.html

    https://github.com/Profluent-AI/OpenCRISPR

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    Happy New Year, Let's Do The Numbers

    On the latest episode of the Conduit Street Podcast, Kevin Kinnally and Michael Sanderson preview Maryland’s budget picture and fiscal outlook, including a breakdown of the driving forces behind the record State budget surplus, higher-than-expected tax receipts, and bullish revenue projections.

    Plus, a look at the Spending Affordability Committee’s recommendations to help guide fiscal 2023 budget decisions, including shoring up reserve funds, repaying unfunded liabilities, and prioritizing one-time construction costs.

    The Conduit Street Podcast is available on major platforms like Spotify, Apple Podcasts, Google Podcasts, and more. Episodes are also available on MACo’s Conduit Street blog.

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    Listen to previous episodes of the Conduit Street Podcast on our website.

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