Episode 73. Pascual Jordan's Duplicity: Ryan Dahn

Peter Agre received the 2003 Nobel Prize in Chemistry for his discovery of aquaporins. Peter is a Bloomberg Distinguished Professor in Molecular Microbiology and Immunology at Johns Hopkins Bloomberg School of Public Health, and he also directed the Johns Hopkins Malaria Research Institute until 2023. Today we discuss the history of malaria research, and Peter reflects on being a scientist. The interview is followed by Peter's keynote lecture for the University of Arizona One Health symposium, which he gave on February 12, 2024.

In 1994, while attending graduate school at the University of California, Berkeley, I had the pleasure of seeing a lecture by Oliver Sacks in which he discussed his work on sleeping sickness and various other neurological disorders. He also discussed his thoughts on the economy of a life. Today's episode is that lecture in full, with all the insights and charm that was Oliver Sacks.

Novichok is the most deadly chemical weapon ever developed. With us to discuss the history of Novichok is Vil Mirzayanov. Vil worked in the secret Soviet chemical weapons laboratory that developed Novichok. He revealed its existence to the world in 1991 and was then arrested by the Russian counterintelligence service and prosecuted in a secret trial. He won his freedom with the help of an international group of scientists, including three who have appeared as guests on this podcast. He then immigrated to the United States and published his story in the book State Secrets. An Insider's Chronicle of the Russian Chemical Weapons Program, published in 2009 by Outskirts Press.

How could a brilliant scientist and mathematician, an innovator in quantum theory, who worked closely with Jewish colleagues, become an ardent Nazi? How did this man, who has a field of mathematics named after him, escape the scrutiny of his colleagues? And what happened to him upon the collapse of Nazi Germany? The scientist who straddled this strange world of physics and Nazism was Pascual Jordan. With us to explain the history of Pascual Jordan is Ryan Dahn. Ryan is a writer, editor, science historian, and translator. He is the books editor at Physics Today, the flagship physics magazine of the American Institute of Physics.

Many of the most important secrets held in international contests are technological or scientific in nature, and wars are often settled due to technological superiority of one side over the other. This leads spy agencies to employ all manner of trickery and tools to obtain those secrets. With us to explore the history of scientific espionage is Eli Lake. Eli was a senior national security correspondent for The Daily Beast and Newsweek, and a syndicated columnist with Bloomberg. Eli is now a columnist for the Free Press and the host of the Re-Education Podcast on Nebulous media. Eli is also a contributing editor for Commentary Magazine.

A retrospective on the Franck-Hertz experiment, which resulted in James Franck and Gustav Hertz receiving the 1925 Nobel Prize in Physics.

Image credit: By Infoczo - Own work, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=35281920

A retrospective on James Franck, recipient of the 1925 Nobel Prize in Physics.

The ability to extract DNA from ancient fragments of biological material has revolutionized our understanding of recent evolutionary history, including human evolution and phylogeography. Analysis of ancient DNA in tandem with radiocarbon dating, along with traditional archeological techniques, has led to a flurry of discoveries. With us to discuss this research is Maanasa Raghavan. Maanasa is a Neubauer Family Assistant Professor of Human Genetics at the University of Chicago. 

The world just experienced a devastating pandemic, yet in the context of historical pandemics, COVID-19 was a relatively minor event in the history of disease. What do we know about the history of pandemics, including before written records, and what can we learn from this history? With us to answer these and other questions about the origins of epidemics and pandemics is Leslie Reperant. Leslie graduated with a doctorate of veterinary medicine at the National Veterinary School of Lyon, France in 2004 and obtained a PhD at Princeton University in the Department of Ecology and Evolutionary Biology in 2010. Leslie's doctoral and post-doctoral studies focused on the interplay between the pathogenesis and evolution of influenza viruses, and on factors driving pathogen emergence and spread. Leslie is the author of Fatal Jump: Tracking the Origins of Pandemics, published in 2023 by Johns Hopkins University Press.

Before the advent of the germ theory of disease in the 1870s, quarantine provided one of the few effective means to prevent or alleviate epidemics. The Lazaretto quarantine station in Philadelphia illustrates the history of quarantine both before and after the discovery of pathogenic microbes. With us to explore the history of 18th and 19th century quarantine in Philadelphia, and what it meant for public health, is David Barnes. David teaches the history of medicine and public health at the University of Pennsylvania, where he is an Associate Professor of History and Sociology of Science. David received a BA in history from Yale in 1984 and a Ph.D. in history from the University of California, Berkeley in 1992. His books include The Making of a Social Disease: Tuberculosis in Nineteenth-Century France (University of California Press, 1995), The Great Stink of Paris and the Nineteenth-Century Struggle against Filth and Germs (Johns Hopkins University Press, 2006), and Lazaretto: How Philadelphia Used an Unpopular Quarantine Based on Disputed Science to Accommodate Immigrants and Prevent Epidemics (Johns Hopkins University Press, 2023).