Etrasimod, a Sphingosine 1-Phosphate Receptor Modulator, for Moderate-Severe Ulcerative Colitis: New Options for Oral Therapy

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Ahmad Abu-Heija, MBBS discuss “Comparison of a novel, flavor-optimized, polyethylene glycol and sulfate bowel preparation with oral sulfate solution in adults undergoing colonoscopy,” by Summarizing Bhandari R, Goldstein M, Mishkin DS, et al. J Clin Gastroenterol; 2023;57(9):920-927.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Joseph Elmunzer, MD, MSc discuss “Indomethacin with or without prophylactic pancreatic stent placement to prevent pancreatitis after ERCP: a randomised trial,” by Elmunzer BJ, Foster LD, Serrano J et al. Lancet 2024; 403: 450-58.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Sonali Paul, MD discuss “Continued treatment with tirzepatide for maintenance of weight reduction in adults with obesity: The SURMOUNT-4 randomized clinical trial,” by Aronne LJ, Horn DB, Bays HE, et al. JAMA 2024; 3310: 38-48.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Swathi Eluri, MD, MSCR discuss “Non-erosive gastro-oesophageal reflux disease and incidence of oesophageal adenocarcinoma in three Nordic countries: population based cohort study,” by Holmberg D, Giola S, von Euler-Chelpin M, et al. BMJ 2023; 382: e076017

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Rahul Dalal, MD, MPH discuss “Mirikizumab as Induction and Maintenance Therapy for Ulcerative Colitis,” by D'Haens G, Dubinsky M, Kobayashi T, et al. N Engl J Med. 2023 Jun 29;388(26):2444-2455.

Philip Schoenfeld, MD, MSEd, MSc and Bharati Kochar, MD, MS discuss “Early Ileocecal Resection for Crohn’s Disease is Associated with Improved Long-Term Outcomes Compared with Anti-Tumor Necrosis Factor Therapy: A Population-Based Cohort Study,” by Agrawal M, Ebert AC, Poulsen G, et al. Gastroenterology 2023; 165:976-985.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Jacqueline Gaulin discuss “Endoscopist-Level and Procedure-Level Factors Associated with Increased Adenoma Detection With the Use of a Computer-Aided Detection Device,” by Shaukat A, Lichtenstein DR, Chung DC, et al. Am J Gastroenterol 2023; 118: 1891-94.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Jeffrey Lee, MD, MPH discuss “Root-cause Analysis of 762 Danish Post-colonoscopy Colorectal Cancer Patients,” by Troelsen FS, Sørensen HT, Pedersen L, Brix LD, Grode LB, Dekker E, Erichsen R. Clin Gastroenterol Hepatol. 2023 Nov;21(12):3160-3169.e5. Epub 2023 Apr 7.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Philip Okafor, MD, MPH discuss “Thalidomide for Recurrent Bleeding Due to Small Intestinal Angiodysplasia,” by Chen H, Wu S, Tang M et al. N Engl J Med 2023 Nov 2;389(18):1649-1659.

Philip Schoenfeld, MD, MSEd, MSc (Epi) and Jacqueline Gaulin discuss “Amitriptyline at Low-Dose and Titrated for Irritable Bowel Syndrome as Second-Line Treatment in Primary Care (ATLANTIS): A Randomised, Double-Blind, Placebo-Controlled, Phase 3 Trial,” by Ford AC, Wright-Hughes A, Alderson S, et al. Lancet 2023; 402: 1773-85.