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    Fix your body clock to improve long term health with Prof. Satchin Panda

    enJune 20, 2024

    Podcast Summary

    • Circadian rhythmsCircadian rhythms regulate various functions in every cell and organ, and disruptions can damage health. Adjusting lifestyles to match these rhythms can lead to health improvements in weeks.

      Our body follows a 24-hour cycle, known as circadian rhythms, which govern various functions in every cell and organ in our body. These rhythms regulate hormones, brain chemicals, digestive juices, enzymes, and even genes. Disruptions to these rhythms, such as eating breakfast at the wrong time or inconsistent sleep patterns, can damage our health. Professor Sachin Pander, a leading circadian rhythm researcher, emphasizes that everyone has the same 24-hour clock, and adjusting our lifestyles to match these rhythms can lead to health improvements in just weeks. It's not just about sleep; our heart rate, blood pressure, and metabolism also follow these cycles. Understanding circadian rhythms can help us make healthier choices and reduce the risk of chronic diseases.

    • Circadian rhythm disruptionsDisruptions to our circadian rhythm, such as irregular sleep patterns or daylight saving time, can lead to negative health consequences including increased risk for heart disease, digestive issues, and even cancer.

      Our circadian rhythm, the internal clock that regulates various functions in our body, plays a crucial role in preparing us for daily activities and ensuring optimal health. During sleep, our body undergoes repair and rejuvenation processes, which are essential for maintaining good health. Disruptions to this circadian rhythm, such as irregular sleep patterns or daylight saving time, can lead to negative health consequences, including increased risk for heart disease, digestive issues, and even cancer. Our body's internal clock is constantly preparing us for what's to come, and when it's disrupted, it can have detrimental effects on our overall well-being. It's important to respect our body's natural rhythms and prioritize good sleep hygiene to ensure our body can carry out these vital processes effectively.

    • Circadian rhythm disruptionsDisruptions to our internal clock can negatively impact various body functions, increasing the risk for diseases, such as those affecting the gut and skin, and may lead to higher risks for people working non-daytime hours

      Our bodies have an internal clock, or circadian rhythm, which regulates various functions including metabolism, cell repair, and even heart rate. Disruptions to this rhythm, such as changing work hours or eating patterns, can lead to negative health consequences. For instance, the body cannot effectively repair the gut lining or skin when it's still digesting food or when we're exposed to sunlight, respectively. Additionally, certain chemical reactions in the body, like the process of breaking down and making fat, cannot occur at the same time. By understanding and respecting our body's natural rhythms, we can make lifestyle choices that promote better health. Ignoring these rhythms, as many of us do in our modern lives, can lead to increased risk for various diseases. Studies have shown that people who work evening or night shifts are at a higher risk for diseases compared to those with regular daytime hours.

    • Shift work and health risksShift work and irregular lifestyles can disrupt circadian rhythms, increasing the risk for metabolic, cardiovascular diseases, and some types of cancer. Time-restricted eating, a new approach to maintaining a healthy circadian rhythm, shows promising results in studies.

      Shift work, which affects a significant portion of the population in both industrialized and developing countries, poses a high risk for various metabolic and cardiovascular diseases, as well as some types of cancer. This risk is not limited to those who work traditional shift schedules, but also extends to individuals whose lifestyles mimic those of shift workers, such as those who regularly stay up late or eat late into the night. Our circadian rhythms, which regulate our sleep-wake cycles and other bodily functions, are influenced by both light and food intake. Disruptions to these rhythms, such as those caused by late-night eating, can negatively impact various organs and systems in the body. Time-restricted eating, or limiting the hours during the day when food is consumed, is a relatively new approach to maintaining a healthy circadian rhythm and has shown promising results in various studies.

    • Fasting windowRestricting eating to an 8-hour window instead of 24 hours can improve health outcomes for mice on an unhealthy diet, suggesting the importance of meal timing in addition to what and how much we eat. Humans should aim for a 12-hour eating window, with a 14-16 hour fasting period, but individual needs may vary.

      Restricting eating to an eight-hour window instead of allowing access to food around the clock can significantly improve health outcomes for mice, even when they're consuming an unhealthy diet. This discovery, which has been replicated in multiple studies, suggests that the timing of food consumption may be just as important as what we eat and how much we eat. For humans, it's estimated that less than 10% of people actually eat all their food within a 12-hour period, and many consume extra calories in the evening. The current recommendation is for most people to aim for eating all their food within a 12-hour window each day, allowing for a 14-16 hour fasting period, which may help improve overall health. However, individual needs and health conditions may require adjustments to this general guideline.

    • Time-restricted eating benefitsReducing eating window by 3+ hours leads to improved sleep, reduced BP & cholesterol, increased gut bacteria, and larger reductions in body fat, waist size, and better BG control than gov advice.

      Time-restricted eating, which involves reducing your eating window by several hours, can lead to numerous health benefits. These benefits include improved sleep, reduced blood pressure and cholesterol levels, and increased good bacteria in the gut. A recent study published in Nature Medicine showed that the ZOE membership, which helps people make smarter food choices based on their body's unique response, was more effective in improving health than government advice. Participants in the study saw larger reductions in blood fat, body weight, waist size, and better blood sugar control. Additionally, they reported improved mood, less hunger, and better sleep and energy levels. However, it's important to note that while time-restricted eating can help improve nutrition, it's not a free pass to eat unhealthy foods during your eating window. In fact, many people who practice time-restricted eating also make a conscious effort to eat healthier meals and snacks, and reduce their alcohol intake. Overall, reducing your eating window by three or more hours can lead to significant health improvements, and the specific benefits can vary depending on individual factors such as current eating habits and health conditions.

    • Circadian Rhythm DisruptionsMaintaining a consistent sleep schedule, avoiding caffeine after 2 p.m., aligning meal times with the body's natural cycle, and minimizing artificial light exposure in the evening can help maintain a healthy circadian rhythm and improve overall well-being.

      Our bodies have a natural 24-hour circadian rhythm that affects various functions, including sleep, metabolism, and organ health. Disruptions to this rhythm, such as consuming caffeine too close to bedtime or irregular eating patterns, can negatively impact health. To maintain a healthy circadian rhythm, it's recommended to avoid caffeine after 2 p.m., establish a consistent sleep schedule, and align meal times with the body's natural cycle. Light exposure also plays a role in regulating the circadian rhythm, making it essential to minimize artificial light exposure in the evening. Recent studies suggest that humans, especially in the Western world, are not eating within the recommended 12-hour window, which could contribute to various health issues. By respecting our body's natural rhythm and making simple lifestyle adjustments, we can improve our overall well-being.

    • Time-restricted eatingLimiting food consumption to an 8-10 hour window can lead to better sleep, improved energy, and reduced blood pressure. However, maintaining a balanced diet is crucial for optimal health and avoiding caffeine during the eating window for those with acid reflux or heartburn.

      Time-restricted eating, which involves limiting the hours in a day for consuming food, can lead to various health benefits such as better sleep, improved energy, and reduced blood pressure. This eating pattern suggests an eight to ten-hour window for food consumption, which can result in significant improvements, especially over a longer period of three to six months. However, it's essential to note that this approach doesn't give a free pass to consume unhealthy foods. Instead, maintaining a balanced and healthy diet is crucial for optimal health. Additionally, individuals with acid reflux or heartburn should be cautious about consuming caffeine, particularly black coffee, during their eating window as it may exacerbate their symptoms. Overall, time-restricted eating offers a promising approach to improve overall health and wellbeing, but it's essential to remember that what we eat remains the foundation of good nutrition.

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    Fix your body clock to improve long term health with Prof. Satchin Panda

    Fix your body clock to improve long term health with Prof. Satchin Panda

    Our modern lifestyles mean that most of us don’t live our lives in sync with our circadian rhythms, which puts our health and well-being at risk. Eating and sleeping at the right time are important tools to help us align our circadian rhythms and reduce our risk of chronic disease. 

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    Timecodes:

    00:00 Introduction

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    Satchin’s books:



    Books by our ZOE Scientists:



    Studies referenced in today’s episode: 


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    Timecodes

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    Timecodes:

    00:00 Introduction

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    Timecodes

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    17:20 Preventing allergies during pregnancy

    20:30 Nutrition in childhood and adolescence

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    36:00 Longevity supplement myths

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    56:30 Becoming a ZOE member is like having a nutritionist in your pocket!

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