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    Guest Series | Dr. Matthew Walker: Protocols to Improve Your Sleep

    enApril 10, 2024
    What factors influence optimizing sleep quality?
    How can CBD potentially improve sleep quality?
    Why is THC not recommended for sleep?
    What role does caffeine play in sleep disruption?
    How do sleep hygiene practices affect overall sleep health?

    Podcast Summary

    • Exploring Factors for Optimal SleepConsider factors like light, temperature, substances, and focus on quality, quantity, regularity, and timing for better mental and physical health. Utilize tools like customized mattresses, fitness wearables, and meditation apps to enhance sleep.

      Optimizing sleep involves considering various factors such as light, temperature, and avoiding substances like alcohol, caffeine, and cannabis. By focusing on the quality, quantity, regularity, and timing of sleep, individuals can improve their mental health, physical health, and performance. Tools like Helix Sleep's customized mattresses and Woop's fitness wearable device can help enhance sleep quality, while the Waking Up meditation app can promote relaxation and focus for better sleep and overall well-being. During this episode of the Huberman Lab, Dr. Matthew Walker and Andrew Huberman discussed these topics and more, providing valuable insights for anyone seeking to optimize their sleep.

    • Improving Sleep: Conventional and Unconventional MethodsImplementing sleep hygiene practices like regularity, darkness, and avoiding stimulating substances, along with advanced techniques like meditation apps and yoga nidra, can enhance sleep quality and overall well-being.

      Optimizing sleep involves both conventional and unconventional methods. The basics, or "sleep hygiene," include regularity in sleep patterns, maintaining darkness before bed to release melatonin, and avoiding stimulating substances like caffeine and alcohol. More advanced techniques include using meditation apps like Waking Up for guided meditations and yoga nidra sessions. The science behind yoga nidra shows enhanced dopamine levels in the brain, leading to mental and physical readiness. Additionally, Dr. Matthew Walker emphasizes the importance of darkness before bed and the role of melatonin in regulating sleep. By implementing these practices, individuals can improve their sleep quality and overall well-being.

    • The Power of Morning LightMorning light exposure boosts alertness, mood, and focus while increasing cortisol amplitude. Minimize evening artificial light for optimal sleep and wake cycle.

      Exposure to bright light in the morning can significantly improve alertness, mood, and focus throughout the day, while also increasing the amplitude of the morning cortisol spike. This is because the sensitivity of the circadian visual system, which helps regulate our sleep-wake cycle, is relatively low in the morning, requiring a significant amount of bright light to effectively wake us up and suppress sleepiness signals like melatonin. Additionally, bright light in the morning can help control the amplitude of cortisol, which is highest in the morning and lowest in the evening, contributing to better mood, focus, and ease of falling asleep at night. However, it's important to note that excessive artificial light exposure in the evening can disrupt our circadian rhythm and make it difficult to fall asleep, so it's crucial to minimize artificial light exposure as much as possible after sundown. Overall, incorporating bright light exposure in the morning and minimizing artificial light exposure in the evening can help optimize our sleep and wake cycle for better overall health and well-being.

    • Cortisol's impact on sleep for insomniacsInsomniacs experience a cortisol rise during sleep onset and sometimes in the middle of the night, disrupting sleep maintenance.

      Cortisol levels play a significant role in sleep patterns, particularly for those experiencing insomnia. Healthy individuals and insomniacs show similar cortisol levels throughout the day, but insomniacs experience a rise in cortisol during the sleep onset period and sometimes in the middle of the night. This can disrupt the ability to fall back asleep, leading to sleep maintenance insomnia. To improve sleep quality, maintaining a cool sleeping environment and avoiding long periods of wakefulness in bed are recommended. The association between the bed and wakefulness can be broken by getting out of bed and engaging in relaxing activities until feeling sleepy before returning.

    • Tips for Improving Sleep QualityAvoid screens and electronics before bed, establish a consistent bedtime routine, be mindful of learned associations, cut off caffeine intake at least 10 hours before bed, and limit alcohol intake to improve sleep quality

      Our habits and associations, especially around bedtime, can significantly impact our sleep quality. Here are some specific tips from the discussion: 1. Avoid screens and electronics before bed, as the blue light can disrupt your circadian rhythm and make it harder to fall asleep. 2. Establish a consistent bedtime routine to help train your body to wind down and prepare for sleep. 3. Be mindful of the learned associations you make before bed, such as working in bed or using your bed for activities other than sleep. 4. Try to cut off caffeine intake at least 10 hours before bedtime, as it can disrupt sleep and make it harder to fall and stay asleep. 5. Alcohol may help you fall asleep initially, but it fragments your sleep, disrupts your REM sleep, and can lead to awakenings throughout the night that you may not remember. By being aware of these habits and making intentional choices to support good sleep hygiene, you can improve your overall sleep quality and feel more rested and refreshed each day.

    • Breaking the association between location and sleepMoving to a different location or engaging in relaxing activities can help you fall back asleep when you wake up in the middle of the night.

      The association between the location and the act of sleeping can significantly impact our ability to fall back asleep when we wake up in the middle of the night. The speaker shares his personal experience of breaking this association by getting out of bed and moving to the sofa to sleep, which led him to sleep better. He also suggests alternative methods such as meditation, focusing on breathing, or doing a body scan to distract the mind from ruminating and catastrophizing, which can prevent insomnia. The key is to do anything that takes your mind off itself and the stress of the day, allowing you to relax and fall back asleep more easily.

    • Addressing sleep disorders for optimal sleepTo achieve best sleep quality, deal with sleep disorders first, avoid alcohol consumption, maintain a consistent sleep schedule, and practice relaxation techniques.

      While there are various ways to improve sleep quality, such as avoiding screens before bed, maintaining a consistent sleep schedule, and practicing relaxation techniques, it's important to note that sleep disorders can also interfere with sleep optimization. These disorders, including snoring, sleep apnea, and insomnia, should be addressed with medical professionals before focusing on other sleep improvement methods. Additionally, alcohol consumption can disrupt sleep, not just through the loss of REM sleep but also due to metabolic byproducts like aldehydes. The timing of alcohol consumption is crucial, as even a single glass of wine in the afternoon can impact sleep quality.

    • Moderation is key for alcohol and sleepAvoid regular alcohol consumption before bed, and aim to eat two hours before sleep for optimal sleep quality. Individual preferences and chronotypes impact these recommendations.

      When it comes to alcohol and sleep, moderation is key. There isn't a definitive safe amount of alcohol before bed, and while having a drink or two during an special evening might be worth the trade-off, making it a regular habit could negatively impact your sleep quality. As for food, the timing of your last meal before sleep can affect your sleep quality, but the ideal time varies from person to person. Some people may experience discomfort or heartburn if they eat too close to bedtime, while others might not notice any difference. The data suggests that eating two hours before sleep onset is generally fine, but individual preferences and chronotypes play a role. Regarding macronutrients, a diet high in sugar and low in protein can negatively impact sleep, but more research is needed to determine the ideal macro and micro nutrient dietary recommendations for optimal sleep.

    • Impact of Carb Intake and Caffeine on SleepConsuming complex carbs in the evening may improve sleep due to tryptophan and serotonin production, but potential glucose spikes should be considered. Caffeine significantly impacts sleep, so be mindful of intake.

      The timing and type of carbohydrate intake can impact sleep quality. Some people may experience better sleep after consuming carbohydrates, particularly complex ones, in the evening due to the relationship with tryptophan and serotonin production, which contributes to melatonin production. However, the body's ability to dispose of sugar may be less effective in the evening, leading to potential spikes in glucose levels. The evidence is unclear for individuals without signs of type 2 diabetes or pre-diabetes. Caffeine, the most commonly used drug worldwide, can also significantly impact sleep, with Switzerland being a notable example of high consumption. Individuals should consider being more relaxed about the timing of their food intake and consider the potential effects of caffeine on their sleep.

    • Impact of Caffeine on Sleep QualityExperiment with eliminating afternoon caffeine for better sleep quality, as it can disrupt sleep by making it harder to fall asleep, keeping one in a shallower state, and making it harder to fall back asleep if woken up.

      The timing and amount of caffeine intake can significantly impact sleep quality. The speaker shares their personal experience of consuming caffeine in the morning and tapering off in the early afternoon. However, they question whether this is an optimal caffeine intake pattern and suggest experimenting with abstaining from afternoon caffeine, especially for early birds like themselves. The reason being that caffeine can disrupt sleep by making it harder to fall asleep, keeping one in a shallower state of sleep, and making it harder to fall back asleep if woken up in the middle of the night. The metabolism of caffeine and individual variations in its regulation should also be considered, as the same amount of caffeine can affect different people differently. The speaker suggests tracking sleep with a wearable to observe the impact of eliminating afternoon caffeine on sleep quality.

    • Caffeine's Long-Lasting Effects Disrupt Sleep QualityAvoiding caffeine consumption in the hours leading up to bedtime can help ensure optimal sleep quality, as caffeine's long-lasting effects can disrupt deep sleep, which is crucial for overall health and well-being.

      Consuming coffee, particularly later in the day, can negatively impact the quality of your sleep due to caffeine's long-lasting effects. Caffeine's half-life is around five to six hours, but its quarter-life can last up to 10 to 12 hours. This means that if you consume coffee in the afternoon or evening, significant amounts of caffeine can still be in your system when it's time for bed. This can lead to reduced deep sleep, which is crucial for overall health and well-being. It's important to note that individual responses to caffeine can vary based on genetic factors. Some people may metabolize caffeine more quickly than others, but generally, it's recommended to avoid caffeine consumption in the hours leading up to bedtime to ensure optimal sleep quality. While it's understandable that many people face circumstances that make it difficult to avoid late-night caffeine consumption, it's essential to be aware of the potential consequences and make informed decisions about your health.

    • Cannabis for Sleep: Proceed with CautionLong-term use of THC and CBD for sleep can lead to dependency, disrupted REM sleep, and insomnia during withdrawal. Consider potential risks and legal implications before use.

      While THC and CBD, commonly found in cannabis, can help some people fall and stay asleep, the long-term use can lead to dependency, disrupted REM sleep, and insomnia during withdrawal. InsideTracker, a health optimization platform, advises against their use for sleep due to these potential issues. It's important to consider the potential risks, especially for young people and those with developing brains, as well as the legal implications. If you're interested in trying InsideTracker for personalized health recommendations, use the code "Huberman" on InsideTracker.com for a 20% discount.

    • Exploring CBD's potential role in improving sleep qualityCBD may help reduce anxiety and lower body temperature, promoting better sleep, but more research is required for optimal dosage and full understanding of its effects.

      CBD, a non-psychoactive compound found in cannabis, shows promise in improving sleep quality. However, it's important to note that more research is needed to fully understand its effects and optimal dosage. CBD may work by reducing anxiety, which can help individuals fall asleep more easily, and by lowering body temperature, which is necessary for sleep onset. Additionally, maintaining good sleep hygiene practices, such as regularity, optimizing light exposure, and managing temperature, are essential for overall sleep health. THC, the psychoactive compound in cannabis, is not currently advised for sleep due to its potential negative side effects, including impaired memory and cognitive function.

    • Avoiding habits and substances that disrupt sleepGoing to bed too early or late, increasing caffeine intake, napping during the day, alcohol consumption, and THC/CBD use close to bedtime can negatively impact sleep. Create a buffer between last meal and bedtime, avoid alcohol in large quantities or close to bedtime, and be cautious with caffeine intake to improve sleep quality.

      When dealing with sleep issues, it's important to avoid certain habits and substances that can disrupt your sleep architecture. For instance, going to bed too early or too late after a bad night, increasing caffeine intake, or napping during the day can negatively impact your sleep quality. Additionally, alcohol, food, and THC/CBD consumption close to bedtime can also disrupt your sleep. It's recommended to create a buffer between your last meal and bedtime, avoid alcohol in large quantities or close to bedtime, and be cautious with caffeine intake, especially in the afternoon. While CBD has shown promise, more research is needed to fully understand its effects on sleep. Overall, being aware of these factors can help individuals make informed decisions about their lifestyle choices and improve their sleep quality.

    • Unexpected ways sleep deprivation affects the bodySleep deprivation can impact immune function, cardiovascular health, and hormonal balance, and these effects may not be fully offset by exercise. Personalized strategies and working with a clinician can help improve sleep quality.

      Getting a good night's sleep is crucial for overall health, and poor sleep can have significant impacts beyond just feeling groggy. Matt Miller shared some unexpected ways that sleep deprivation can affect the body, such as disrupting immune function, cardiovascular health, and hormonal balance. He emphasized that these effects may not be completely offset by exercise, and it's important to be mindful of the potential vulnerabilities when sleep is lacking. Another unconventional suggestion for improving sleep is limiting time in bed if struggling, which is a key component of cognitive behavioral therapy for insomnia. By working with a clinician to identify the root causes of sleep issues and implementing personalized strategies, individuals can improve their sleep quality and overall health.

    • Bedtime rescheduling: Make your sleep base strongLimiting time in bed can improve sleep efficiency and duration through sleep restriction therapy.

      Bedtime rescheduling, also known as sleep restriction therapy, is an effective intervention for insomnia. By limiting the amount of time spent in bed, the brain is forced to become more efficient and productive during sleep. This can be compared to making a pizza base where spreading it too thin creates gaps and holes. The same concept applies to insomnia. Instead of trying to sleep longer hours, the goal is to create a strong desire and hunger for sleep by restricting the time spent in bed. This can be done under supervision, and the gradual increase in sleep duration can help retrain the brain to sleep more efficiently. The process can be thought of as hitting the reset button on your sleep. It's important to note that this should be done carefully and under the guidance of a healthcare professional to ensure safety.

    • Rebuilding sleep confidence through sleep restriction therapySleep restriction therapy involves setting constraints, sticking to a consistent bedtime and wake-up time, and practicing a wind-down routine to regain control over sleep.

      Sleep is not a simple on-off process, but rather a complex physiological one that requires preparation and discipline. The technique of sleep restriction therapy, or bedtime rescheduling, can help individuals regain control over their sleep by gradually rebuilding sleep confidence. This method involves setting constraints, such as a consistent bedtime and wake-up time, even if it means getting less sleep initially. The motivation to stick with it should be strong, as it may be challenging at first. A wind-down routine, such as a relaxing activity before bed, is also crucial for signaling to the body that it's time to sleep. Interestingly, counting sheep has been found to be counterproductive, and instead, taking a mental walk through a familiar route in high detail can help distract the mind and facilitate falling asleep. Sleep is essential for overall health and well-being, making these techniques worth the effort.

    • Improve sleep quality through mental walks and guided meditationsMental walks and guided meditations engage procedural memory, keeping the mind focused and embodied for better sleep. Remove clock faces and limit phone use for improved sleep hygiene, leading to faster fall asleep and deeper, more restorative sleep.

      Engaging procedural memory through mental walks or guided meditations can help improve sleep quality by keeping the mind focused and embodied, while removing clock faces from the bedroom and limiting phone use before bed can reduce anxiety and improve overall sleep hygiene. These practices can help individuals fall asleep faster and experience deeper, more restorative sleep. Additionally, anticipatory anxiety caused by constant phone use and checking for notifications can negatively impact sleep quality, leading to shallower sleep and less restorative REM cycles.

    • Exploring Advanced Sleep Enhancement ToolsElectrical stimulation using transcranial direct current is a promising approach for enhancing deep sleep and memory benefits. Ongoing research is investigating the potential of closed-loop stimulation to synchronize electrical pulses with deep sleep waves for optimized sleep quality.

      Advanced sleep enhancement tools are evolving, and they can be categorized into electrical, acoustic, thermal, and kinesthetic manipulation. Among these, electrical stimulation using transcranial direct current is a promising approach. By applying electrode pads to the head and delivering a small electrical current, researchers have been able to boost deep sleep brainwaves and enhance memory benefits. The technique, called closed-loop stimulation, synchronizes the electrical pulses with the brain's deep sleep waves, amplifying their effects. Although the initial study showed impressive results, subsequent replication attempts have had mixed results, but ongoing research continues to explore the potential of this method for optimizing sleep quality.

    • Advanced Technologies for Enhanced SleepClosed-loop brain stimulation and thermal manipulation can significantly improve sleep quality by targeting specific brain waves and thermal trigger zones. Personalized solutions offer optimal benefits but wait for approved and safe products.

      Advanced technologies, such as closed-loop brain stimulation and thermal manipulation, can significantly enhance sleep quality by targeting specific brain waves and thermal trigger zones. Closed-loop brain stimulation measures electrical brain activity and delivers timed responses to boost deep-sleep brainwaves and sleep spindles, providing reliable benefits. Thermal manipulation, on the other hand, leverages the relationship between temperature and sleep by warming up to cool down for sleep onset, staying cool to maintain deep sleep, and warming up to wake up. These methods offer personalized solutions, ensuring optimal benefits for each individual. However, it's crucial to wait for approved and safe products to become available, as attempting DIY methods can lead to severe consequences.

    • Body temperature's impact on sleep qualityWarming feet can help healthy individuals sleep faster & deeper, while cooling the core can boost deep sleep for older adults

      Our body temperature plays a significant role in the quality and speed of our sleep. Research shows that warming the feet or peripheral regions can help healthy individuals fall asleep faster and increase deep sleep, while cooling the core of the body can boost deep sleep in older adults. These findings suggest that addressing thermoregulation issues could be an essential part of improving sleep quality, especially for older adults and those with insomnia. Unfortunately, most people don't have access to thermal suits for this purpose. However, understanding the connection between body temperature and sleep may lead to new methods and technologies to help people get a better night's rest.

    • Improve sleep quality with a warm bath or showerA warm bath or shower before bed can increase deep sleep by 40 minutes and help fall asleep 25 minutes faster, leading to a more restorative sleep experience.

      There are simple, cost-effective ways to improve sleep quality, and one such method is through the use of warm baths or showers before bed. Contrary to popular belief, getting out of a warm bath or shower causes your body to lose heat rapidly, triggering a deeper and more restorative sleep. Studies have shown that this thermal shock can increase deep sleep by nearly 40 minutes and help individuals fall asleep 25 minutes faster. The optimal temperature for a warm bath or shower is around 40 degrees Celsius, and the duration should be around 30 minutes, with segments of rest in between. While saunas can also provide similar benefits, they may not be ideal right before bed due to the risk of dehydration. Researchers are now exploring low-tech solutions, such as foot warming technology, to replicate these thermal benefits. Overall, incorporating a warm bath or shower into your bedtime routine is a simple yet effective way to enhance your sleep experience.

    • Exploring Auditory Stimulation for Enhancing Sleep QualityAuditory stimulation using sub-awakening level volume and slow frequency tones can enhance deep sleep duration and brainwave size, potentially improving memory, but continuous stimulation may inhibit naturally occurring deep sleep waves.

      Researchers have explored various ways to enhance sleep quality, including thermal and electrical stimulation, and more recently, auditory stimulation. The idea behind auditory stimulation is to use sub-awakening level volume and slow frequency tones to sync with the brain's slow waves during deep sleep. Early studies showed promising results in increasing deep sleep duration, but they failed to demonstrate any functional benefits, such as improved memory. Subsequent studies used closed-loop systems to deliver tones in sync with the brain's slow waves, leading to increased deep sleep brainwave size and improved memory. However, continuous stimulation beyond a few instances can inhibit naturally occurring deep sleep brainwaves. Overall, the potential of auditory stimulation as a sleep enhancement tool is promising but requires further research and refinement.

    • Exploring the benefits of acoustic stimulation for sleepAcoustic stimulation, especially closed loop, can increase sleep time and enhance sleep stages. Evidence for white noise machines is unclear, and research on body movement and positioning is promising.

      Acoustic stimulation, particularly closed loop acoustic stimulation, can provide benefits for sleep, including increasing total sleep time and enhancing certain stages of sleep. However, the evidence for white noise machines is equivocal, and more research is needed. Additionally, there is some evidence suggesting that body movement and manipulation of body position may also aid in falling asleep, as seen throughout history with practices like rocking infants to sleep. The study by the University of Geneva even went as far as suspending a bed on chains and attaching a rotating arm to it to investigate the effects of gentle rocking on sleep. These findings add to the growing body of evidence supporting the importance of sensory inputs in optimizing sleep quality.

    • Rocking a bed during sleep enhances deep sleep and memoryRocking a bed at a frequency of 0.25 hertz during sleep can enhance deep sleep, increase falling asleep speed, boost sleep spindles, and lead to modest memory benefits. The vestibular system, particularly the lateral vestibular sensation mechanism, is thought to be responsible.

      Researchers discovered that slowly rocking a bed at a frequency of 0.25 hertz during sleep can enhance deep sleep, increase the speed of falling asleep, and boost sleep spindle oscillations. These findings were replicated across a night of sleep and resulted in a modest memory benefit. The vestibular system, which plays a role in understanding motion and movement, is believed to be the mechanism behind this effect. The lateral vestibular sensation mechanism specifically seems to be crucial, as its absence in mice prevented the sleep-promoting benefits of rocking. This discovery adds to the growing body of evidence supporting the importance of sleep for overall health and well-being.

    • Exploring the connection between vestibular system, proprioception and sleepResearch suggests that losing perception of body position and proprioceptive awareness might be necessary for falling asleep. Lateral vestibular stimulation could compromise proprioception, impacting sleep benefits. Thermal neutrality also plays a role in REM sleep, with the right temperature boosting it but extreme temperatures reducing it.

      There are various ways to enhance sleep quality, from high-cost methods like space travel to low-cost techniques like taking a cold shower in the morning. A potential connection between these methods is the role of the vestibular system and proprioception in sleep. Some research suggests that losing perception of body position and proprioceptive awareness may be necessary for falling asleep. One hypothesis is that lateral vestibular stimulation could compromise proprioception, leading to a loss of sleep benefit. Another emerging area of research is the impact of thermal neutrality on REM sleep, as warming the body to the right temperature can boost REM sleep, but keeping it too hot or too cold can reduce it. Overall, understanding these mechanisms could lead to new ways to enhance sleep quality and duration.

    • New sleep medications called DORAs can help induce naturalistic sleep by blocking wakefulness promoting chemical erexinNew sleep medications called DORAs can improve overall sleep quality, including REM sleep, by selectively blocking the wakefulness promoting chemical erexin, although they are not widely prescribed due to cost and insurance issues.

      Certain sleep medications, known as sedative hypnotics, can interfere with deep, restorative sleep by reducing electrical activity in the brain's slowest frequency range. Conversely, a new class of sleep medications called DORAs (D-O-R-A stands for D2-like orphan receptor antagonists) can selectively block the chemical erexin, which is responsible for promoting wakefulness, and help induce naturalistic sleep. This approach can improve overall sleep quality, including REM sleep, which is important for brain and body health. DORAs are still not widely prescribed due to cost and insurance coverage issues.

    • Manipulating REM sleep with cautionBe aware of potential risks when enhancing REM sleep through methods like acetylcholine precursors, as they may affect deep non-REM sleep and cause increased arousal or difficulty falling asleep.

      While there are methods to enhance REM sleep, such as thermal manipulation and certain medications, it's important to be cautious as these approaches may also impact deep non-REM sleep. Acetylcholine, a neurotransmitter, plays a role in REM sleep, and taking acetylcholine precursors like alpha-GPC could potentially increase REM sleep, but it may also lead to increased aroual and difficulty falling asleep. It's crucial to consider the potential trade-offs and consult with a healthcare professional before trying such approaches. Additionally, it's important to remember that sleep is a complex process involving various neurotransmitters and sleep stages, and trying to manipulate one aspect may have unintended consequences. As always, it's essential to approach sleep enhancement methods with caution and consideration for the overall balance of sleep stages.

    • Exploring advanced techniques for improving sleep qualityAdvanced techniques for sleep improvement include thermal manipulation, auditory stimulation, kinesthetic approaches, and rapid eye movement enhancing drugs. Future advancements in technology hold great promise for sleep enhancement and monitoring.

      Improving sleep quality goes beyond traditional methods and involves various advanced techniques. These include thermal manipulation, auditory stimulation, kinesthetic approaches, and rapid eye movement enhancing drugs. Understanding the history and present state of sleep research is essential, but looking towards the future holds great promise for technological advancements in sleep enhancement and monitoring. For those interested in delving deeper into the science and specific protocols related to napping, caffeine, and other daily life impacting factors, stay tuned for episode three. Remember, supplements can aid in sleep improvement, focus, and hormone support. For more information, visit livemomentus.com/Huberman. Connect with Huberman Lab on social media for science-related content, and consider subscribing to the neural network newsletter for free podcast summaries and protocols. Thank you for your interest in science and for joining this discussion with Dr. Matthew Walker.

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    Huberman Lab
    enAugust 26, 2024

    Dr. Teo Soleymani: How to Improve & Protect Your Skin Health & Appearance

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    Huberman Lab
    enAugust 19, 2024

    Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

    Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries
    I'm honored to share Episode 10, the final episode of Season 1 of Perform with Dr. Andy Galpin. Dr. Andy Galpin is a tenured full professor at California State University, Fullerton, where he co-directs the Center for Sport Performance and leads the Biochemistry and Molecular Exercise Physiology Laboratory. Andy is both a friend and a colleague, and I'm delighted to have assisted in the creation of this podcast. I'm certain you'll both enjoy and learn from it. Season 1 featured 10 episodes, where Dr. Galpin covered everything from building strength, the importance of strength for long-term health, the science of breathing, the benefits of sleep extension, genetic testing for personalized training, and nutrition for injury recovery. While we have Episode 10 of Perform with Dr. Andy Galpin here, please be sure to follow Perform with Dr. Andy Galpin on your preferred platform to listen to all the episodes from Season 1 and to get notified when Season 2 is released. Show notes for this episode can be found at performpodcast.com. Timestamps 00:00:00 Introduction from Dr. Andrew Huberman 00:01:08 Brain Health & Injury   00:05:06 Sponsors: LMNT & Continuum   00:08:16 Nutrition & Supplements for Brain Injury   00:12:44 Brain Injury Categories, Traumatic Brain Injury (TBI), Concussion   00:17:09 Brain Injury Pathophysiology   00:22:16 Burst Capillaries, Initial TBI Response   00:30:03 Delayed TBI Response, Neuroinflammation   00:34:19 Sponsors: Momentous & Maui Nui   00:36:52 Creatine Monohydrate; Second Impact Syndrome   00:41:52 Strength of Evidence Scale, Creatine   00:47:15 Creatine Doses, Frequency, Adverse Issues; Food Sources   00:53:22 Sponsors: AG1 & David Protein   00:56:05 Fish Oil, DHA, EPA   01:00:38 EPA & DHA Dosage, Timing, Adverse Issues; Food Sources; Omega-3 Index   01:04:46 Vitamin B2 (Riboflavin), Vitamin B   01:08:57 Riboflavin Dosages, Timing; Food Sources   01:11:25 Choline   01:18:37 Choline Supplements & Food Sources, Alpha GPC, Dosage   01:21:30 Branched-Chain Amino Acids (BCAAs), Sleep   01:25:04 BCAAs Dosage, Whole Food Sources   01:28:02 Magnesium   01:31:20 Magnesium Dosage, Timing, Supplements, Adverse Issue; Food Sources   01:33:09 Blueberry Anthocyanins   01:35:28 Anthocyanins Dosage; Food Sources   01:37:17 Caffeine & Brain Injury Recovery   01:38:50 Perform Episodes, Perform Newsletter, Acknowledgements   01:41:19 Zero-Cost Support, YouTube, Spotify & Apple Subscribe & Reviews, Sponsors, YouTube Feedback, Social Media   01:42:56 Conclusion by Andrew Huberman   Disclaimer
    Huberman Lab
    enAugust 14, 2024

    Dr. Layne Norton: Tools for Nutrition & Fitness

    Dr. Layne Norton: Tools for Nutrition & Fitness
    In this episode, my guest is Dr. Layne Norton, Ph.D., one of the world’s top experts in nutrition and training for physical fitness. We discuss how to evaluate scientific evidence and the validity of different practices aimed at achieving fat loss, muscle strength and hypertrophy, microbiome health, vitality, and longevity. We explore many hotly debated topics, including fasting, seed oils, saturated fats, sugar, red meat, artificial/low-calorie sweeteners, and GLP-1 agonists (e.g., Ozempic). Additionally, we delve into the timing of protein and carbohydrate intake relative to fasting and exercise, fat loss and sleep, and the benefits of dietary protein and fiber on overall health. We also discuss how to accelerate hypertrophy and fat loss, improve strength, whether we need to train to “failure,” how to enhance exercise recovery, and how to manage pain. We cover training before versus after age 50, whether metabolism changes with age, and the connection between muscle health and longevity. We also address why certain behaviors and supplements might work for some people but not others. Listeners to this episode will benefit greatly from Layne’s science-based expertise on a wide range of topics, including health, nutrition, and fitness. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Mateina: https://drinkmateina.com/huberman Eight Sleep: https://www.eightsleep.com/huberman Maui Nui: https://mauinuivenison.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Dr. Layne Norton 00:01:49 Sponsors: Mateina, Eight Sleep, Maui Nui 00:06:39 Science-Based Evidence, Mechanism vs. Outcome 00:14:31 Meta-analysis, Methods, Evidence Quality 00:22:45 Evidence Hierarchy, Randomized Controlled Trials, Cohort Data 00:33:53 Sponsor: AG1 00:35:05 “Don’t Turn Your Brain Off”; Protein Synthesis 00:42:01 Protein Synthesis, Refractory Response; Resistance Training   00:46:05 Protein Intake, Intermittent Fasting & Training 00:54:52 Tool: Total Protein Intake, Distribution & Protein Synthesis 01:00:25 Muscle Quality, Protein Remodeling, Muscle Growth 01:05:34 Sponsor: LMNT 01:06:46 Early vs. Late Time-Restricted Eating; Fasting Blood Glucose & HbA1c 01:10:30 Carbohydrate Timing, Individual Response, Placebo; Tool: Tracking Diet 01:19:50 “The Norton Method”; Tool: Consistency 01:25:16 Resistance & Cardiovascular Training; Competition; Immune System & Rest 01:33:50 Mind & Body Effects, Stress; Belief Effects 01:41:30 Training to Failure, Reps in Reserve, Hypertrophy & Strength Training 01:50:24 Fatigue & Training to Failure, Speed, Strength Training 01:59:06 Tool: Training After 50, Consistency 02:09:12 Fat Cells, Diabetes, Exercise 02:16:50 Metabolism & Age-Related Changes?, Appetite 02:23:17 Ozempic, Mounjaro, GLP-1 Agonists, Lean Mass, “Food Noise” 02:33:42 GLP-1 Agonists, Judgement & Obesity 02:40:19 Sugar, Excess Calories, Body Weight 02:49:16 Satiety, Sugar & Calorie Budget 02:54:56 Tool: Individualization, Context & Diet Psychology 02:57:22 Seed Oils, Butter, Olive Oil 03:06:56 Red Meat, Carcinogenic?; Simple Diet; Fiber Benefits 03:13:43 Saturated Fat, Cholesterol; Seed Oils 03:18:41 Artificial & Low-Calorie Sweeteners, Insulin, Appetite 03:29:06 Artificial & Low-Calorie Sweeteners, Gut Microbiome; Cancer 03:37:58 Tools: Training Recovery, Glycogen Replenishment; Stress & Activity 03:45:56 Collagen Supplementation, Skin & Nails, Whey Protein 03:57:00 Evidence-Based Approach 04:01:41 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures
    Huberman Lab
    enAugust 12, 2024

    Dr. Martha Beck: Access Your Best Self With Mind-Body Practices, Belief Testing & Imagination

    Dr. Martha Beck: Access Your Best Self With Mind-Body Practices, Belief Testing & Imagination
    In this episode, my guest is Dr. Martha Beck, Ph.D., a Harvard-trained sociologist, bestselling author, and one of the world’s foremost experts on personal exploration and development.  Dr. Beck shares specific frameworks and practices to tap into your unique and deepest desires, core truths, and best life direction—all elements that comprise your authentic self. She also explains how to align your work and relationships of all kinds with your true self and how to embrace the discomfort and process of leaving unhealthy relationships. We discuss how to deal with negative thoughts and emotions, grapple with societal norms, and improve body awareness to gauge your inner truth. We also discuss codependency and self-abandonment - and how to exit and recover from these experiences.  By the end of the episode, you will have learned numerous practical tools to access your best self and live a richly fulfilling life.  Access the full show notes for this episode at hubermanlab.com. Dr. Beck's Wayfinder Life Coach Training: https://marthabeck.com/life-coach-training Thank you to our sponsors AG1: https://drinkag1.com/huberman BetterHelp: https://betterhelp.com/huberman Helix Sleep: https://helixsleep.com/huberman LMNT: https://drinklmnt.com/huberman Waking Up: https://wakingup.com/huberman Timestamps 00:00:00 Dr. Martha Beck 00:01:34 Sponsors: BetterHelp, Helix Sleep & LMNT 00:05:34 Tool: Perfect Day Exercise 00:15:31 “Clear Eyed”, Male vs. Female 00:23:31 Family & Work; Directed Attention & Miracles 00:30:21 Sponsor: AG1 00:32:10 Unease, Restlessness & Guilt; Life Worth, Fear 00:37:22 Accessing the Subconscious; Compassionate Witness Self 00:46:16 Finding Self, Suffering, Anxiety; Tool: “KIST”, Self-Parenting 00:54:01 Self, Radiance, Death; Awakening 00:59:14 Suffering & Compassionate Attention 01:02:10 Challenging Internal Thoughts, Understanding Truth, Body & Mind; 01:08:44 Sponsor: Waking Up 01:10:20 Western Society & Pressure 01:18:30 Tool: Sensing Truth in Body; Meditation, “Stopping the World” 01:25:02 Energy, Magnetoreception, Pet’s Death 01:33:49 Lying to Ourselves, Addiction 01:38:18 Tool: “Integrity Cleanse”, Lies; The Light 01:47:32 Relationship with Loss; Love, Self-Abandonment & Codependency 01:55:10 Romantic Relationships; Jobs & Family 02:02:06 Hurting Others, Relationship Imbalance 02:06:55 Tool: True Empathy 02:11:26 “Happiness is an Inside Job”, Codependency 02:18:58 Live Your Joy, Western Society 02:24:41 Relationships, Love & Integrity, “Feeling Good By Looking Weird” 02:30:42 “I Like It!”, Punk Rock Music, Love 02:34:24 Honesty & Essential Self; Helping People & Healers 02:42:12 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures
    Huberman Lab
    enAugust 05, 2024

    AMA #18: Cold Therapy Advice, Skin Health Tips, Motivation, Learning Strategies & More

    AMA #18: Cold Therapy Advice, Skin Health Tips, Motivation, Learning Strategies & More
    Welcome to a special edition of the 18th Ask Me Anything (AMA) episode, part of Huberman Lab Premium. This episode is a recording of the live stream AMA, exclusive to our Premium members. We've decided to make the full-length version available to everyone, including non-members of Huberman Lab Premium. Huberman Lab Premium was launched for two main reasons. First, it was launched in order to raise support for the main Huberman Lab podcast — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation and other donors. If you're not yet a member but enjoyed this full-length livestream AMA, we invite you to join Huberman Lab Premium. By subscribing, you'll gain access to exclusive benefits including our regular monthly full-length AMA episodes, AMA transcripts, podcast episode transcripts, early access to live events and more. Additionally, a significant portion of your membership proceeds contributes to advancing human scientific research. You can learn more about the research we were able to support in our Annual Letter 2023. If you're a Huberman Lab Premium member, you can access the transcript for this AMA episode here. Timestamps 00:00 Introduction & Announcements 00:15 Supporting Mental & Physical Health Research 01:56 Exciting New Research Initiatives 03:39 Skin Health & Appearance 14:46 Cold Therapy Benefits & Guidelines 21:18 Self-Motivation Strategies 27:05 Understanding REM Sleep 28:45 Morning Routine: Exercise & Cold Exposure 29:17 The Importance of REM Sleep 29:49 Non-Sleep Deep Rest (NSDR) Protocols 31:27 REM Sleep Rebound & Compensation 32:55 Impactful School Strategies for Learning 34:19 Meditation & Micro Gaps in Learning 39:13 Physical Activity & Learning 41:01 Exploring Shilajit & Testosterone 47:51 Writing Process & Overcoming Obstacles 51:32 Addiction & Recovery Resources 53:47 Closing Remarks & Gratitude Disclaimer & Disclosures
    Huberman Lab
    enAugust 02, 2024

    Dr. Peter Attia: Supplements for Longevity & Their Efficacy

    Dr. Peter Attia: Supplements for Longevity & Their Efficacy
    In this episode, my guest is Dr. Peter Attia, M.D., a Stanford and Johns Hopkins School of Medicine-trained physician expert in improving human healthspan and lifespan. Dr. Attia is also the host of The Drive podcast and author of the best-selling book Outlive.  We discuss the NAD pathway in human cells and its possible links to aging and health. We evaluate how supplementation can augment molecules in the NAD pathway; we compare NAD, NMN, and NR, different routes of administration, their safety, and bioavailability. Then, we discuss the broader research and clinical literature on longevity to decide if supplementation with NAD, NR, NMN, rapamycin, or resveratrol can indeed extend lifespan.  Finally, we each describe our supplement regimens and compare the role of supplementation to behaviors such as sleep, nutrition, and exercise for longevity. We also discuss whether tests of biological age are true indicators of aging and whether normal radiation levels increase cancer risk.  Listeners of this episode will learn if supplements purported to improve lifespan show any efficacy and the behaviors and other factors that can prevent disease and extend lifespan. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/huberman Levels: https://levels.link/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps 00:00:00 Dr. Peter Attia, NAD Pathway 00:02:31 Sponsors: LMNT, Levels & Eight Sleep 00:06:38 Categories of Longevity Approaches 00:17:22 Peter’s Supplements; Rapamycin & Research Data 00:25:01 NAD Pathway: Energy & DNA Repair; Knock-Out & Knock-In, Klotho 00:30:35 Sponsor: AG1 00:32:25 Yeast, Sirtuins, Caloric Restriction & Lifespan 00:38:56 Sirtuins, Transgenic Mice, Gender & Lifespan 00:43:42 DNA Repair, Sirtuins, Cancer; Resveratrol 00:53:31 Perform with Dr. Andy Galpin Podcast 00:54:18 NAD & NADH, Reactive Oxygen Species (ROS), Mitochondrial Health 01:02:17 NAD vs NR vs NMN Supplementation; IV & Oral Routes 01:11:33 NR vs. NMN, Doses, Side Effects; Interventions Testing Program 01:17:43 Fatty Liver Disease & NR; NMN & Glucose; Clinical Significance 01:25:17 Safety & FDA, NMN & NR Supplementation; Skin Cancer Benefits 01:30:38 Longevity, NR & NMN Supplementation, Inflammation 01:41:00 Rapamycin & Immune Function 01:44:37 Biological Aging Tests, Chronologic & Biologic Age; Vigor  01:55:24 Radiation & Cancer Risk 01:58:12 Tool: Self-Care in 50s-70s & Aging; Energy Decline 02:07:12 Tool: Exercise Timing & Energy Levels 02:11:22 Peter’s Supplements 02:18:46 Andrew’s Supplements 02:24:34 Tool: Supplement Use vs. Critical Behaviors; Titanic Analogy  02:26:52 NAD Pathway Supplementation for Longevity? 02:28:52 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Social Media, Neural Network Newsletter Disclaimer
    Huberman Lab
    enJuly 29, 2024

    Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity

    Dr. Stacy Sims: Female-Specific Exercise & Nutrition for Health, Performance & Longevity
    In this episode, my guest is Dr. Stacy Sims, Ph.D., an exercise physiologist, nutrition scientist, and expert in female-specific nutrition and training for health, performance, and longevity. We discuss which exercise and nutrition protocols are ideal for women based on their age and particular goals. We discuss whether women should train fasted, when and what to eat pre- and post-training, and how the menstrual cycle impacts training and nutrition needs. We also explain how to use a combination of resistance, high-intensity, and sprint interval training to effectively improve body composition, hormones, and cardiometabolic health, offset cognitive decline, and promote longevity.  We also discuss supplements and caffeine, the unique sleep needs of women based on age, whether women should use deliberate cold exposure, and how saunas can improve symptoms of hot flashes and benefit athletic performance. Dr. Sims challenges common misconceptions about women’s health and fitness and explains why certain types of cardio, caloric restriction, and low-protein diets can be harmful to women’s metabolic health. Listeners will learn a wealth of actionable information on how to improve their training and nutrition to enhance their health and how to age with greater ability, mobility, and vitality. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Maui Nui Venison: https://mauinuivenison.com/huberman  Eight Sleep: https://eightsleep.com/huberman   Waking Up: https://wakingup.com/huberman  Timestamps 00:00:00 Dr. Stacy Sims 00:02:24 Sponsors: Maui Nui, Eight Sleep & Waking Up 00:07:03 Intermittent Fasting, Exercise & Women 00:12:50 Cortisol & Circadian Rhythm, Caffeine & Training 00:17:25 Reps in Reserve, Rate of Perceived Exertion (RPE); Age & Women 00:21:06 Pre-Training Meal & Brain, Kisspeptin 00:26:45 Post-Training Meal & Recovery Window 00:29:59 Sponsor: AG1 00:31:48 Hormones, Calories & Women 00:34:24 Women, Strength Improvements & Resistance Training 00:39:10 Tool: Women & Training Goals by Age Range 00:44:16 Women, Perimenopause, Training & Longevity 00:47:14 Women & Training for Longevity, Cardio, Zone 2 00:51:42 Tools: How to Start Resistance Training, Machines; Polarized Training 00:58:23 Perform with Dr. Andy Galpin Podcast 00:59:10 Menstrual Cycle & Training, Tool: Tracking & Individual Variability 01:04:31 Tool: 10-Minute Rule; High-Intensity Training & Menstrual Cycle 01:08:36 “Train Hard & Eat Well”; Appetite, Nutrition & Menstrual Cycle 01:12:22 Oral Contraception, Hormones, Athletic Performance; IUD 01:20:57 Evaluating Menstrual Blood, PCOS; Hormones & Female Athletes 01:26:31 Iron, Fatigue; Blood Testing & Menstrual Cycle 01:29:33 Caffeine & Perimenopause; Nicotine, Schisandra 01:34:24 Deliberate Cold Exposure & Women, Endometriosis; Tool: Sauna & Hot Flashes 01:42:19 Tools: “Sims’ Protocol”: Post-Training Sauna & Performance; “Track Stack” 01:49:37 Women, Hormones & Sleep, Perimenopause & Sleep Hygiene 01:52:54 Supplements: Creatine, Water Weight, Hair Loss; Vitamin D3 01:57:21 Protein Powder; Adaptogens & Timing 02:00:11 Pregnancy & Training; Cold & Hot Exposure 02:06:19 Tool: Women in 50s & Older, Training & Nutrition for Longevity 02:09:38 Tool: Women in 20s-40s & Training, Lactate 02:12:18 Tool: What is High-Intensity Training?, Cardiovascular Sets & Recovery 02:17:22 Training for Longevity, Cellular & Metabolic Changes 02:19:30 Nutrition, 80/20 Rule 02:23:30 Listening to Self 02:26:00 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter  Disclaimer & Disclosures
    Huberman Lab
    enJuly 22, 2024

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    What are some simple steps to improving health? Answer: Improving stress levels and sleep quality can be simple steps to improving health.

     

    Why is being too rigid with lifestyle change negative? Answer: Being too rigid with lifestyle changes can negatively impact mental health.

     

    How can the wellness industry be dangerous?Answer: The wellness industry can be dangerous because it promotes rigid rules and labels, which can be detrimental to one's health.

     

    Why is it important to take a look at stress and emotional health to navigate a healthy lifestyle? Answer: It is important to take a look at stress and emotional health to navigate a healthy lifestyle because they can have a significant impact on physical health.

     

    What is Rose Harwood's experience with fibromyalgia? Answer: She had experienced fibromyalgia in their teenage years and had difficulty managing it, but she has since found ways to manage it and believes that getting a label for it is not always necessary.

     

    What inspired Nick to make a documentary about fibromyalgia?Answer: Nick was approached by someone with an idea to make a documentary about fibromyalgia, which appealed to him as he was already at a point of wanting to expand their creativity and open to new possibilities.

     

    What is Long COVID and how does it relate to fibromyalgia? Answer: Long COVID is a condition where people experience symptoms of COVID-19 for weeks or months after the initial infection. The episode suggests that there are similarities between Long COVID and fibromyalgia, and watching the documentary about fibromyalgia may provide education that applies to Long COVID.

     

    What is the healthcare system's role in the opioid epidemic? Answer: The healthcare system has created a population of people addicted to painkillers because they don't know what else to do. The system has given a lot of painkillers but not much other treatment, which has contributed to the opioid epidemic.

     

    Our Guests:

    The Role Crying Plays in Your Wellness

    The Role Crying Plays in Your Wellness

    Do you know why you cry? What role does it play in your health? It is fascinating that we are the only species that is capable of emotional tears, as opposed to the other two types of tears that we all have (hydration tears - just keep our eyes moist, and protective tears - like what happens when you cut into an onion, or when people get pepper-sprayed, or a big dust of wind blows in your eyes). In this episode we go into:

    • Why do you cry
    • What role it plays in your health
    • What you can learn from your tears
    • The relationship between our stress hormones and tears
    • How to deal with children and their tears and what we can learn from them May you never look at crying quite the same!

    If you have any questions about this or any other episode, feel free to reach out to me either on my website at www.marlabarr.com or on Instagram at @marla.barr

    If you have time, I would appreciate it if you could let me know what you think of the episodes by rating and reviewing this show. I love seeing everyone’s feedback, comments and questions (it always gives me so many ideas for upcoming episodes). Thank you! Thank you! Thank you! Just for listening along, I give you 5 stars :)

    Wishing you all love and light – Marla

    To join Marla's Wellness Insiders' email group, you can follow the link here

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