Logo
    Search

    Podcast Summary

    • Expert assistance and valuable tools for project successFerguson and Squarespace prioritize customer success through expert assistance and valuable tools, while the Stuff You Should Know podcast explores fascinating topics with humor and knowledge.

      Both Ferguson and Squarespace prioritize their customers' success. At Ferguson, they provide expert assistance in product selection, order facilitation, and delivery coordination to ensure a smooth project from start to finish. Meanwhile, Squarespace offers valuable analytics tools to help businesses grow by understanding their site visits, sales, and marketing effectiveness. In the world of education, the Stuff You Should Know podcast explores the fascinating topic of therapeutic hypothermia, a scientific process that can potentially stave off death and could be the future of modern medicine. While discussing this topic, the hosts couldn't help but poke fun at each other with their signature humor. Overall, these companies and the podcast provide valuable resources and knowledge to make every project, business, or learning experience a success.

    • Historical use of hypothermia for medical benefitsFrom ancient battlefields to modern medicine, hypothermia has shown potential in reducing tissue damage, especially in traumatic brain injuries and cardiac arrest cases.

      The use of medically induced hypothermia, also known as therapeutic hypothermia, dates back to the Napoleonic Wars when soldiers who were left in the cold after battles actually fared better than those kept warm. The practice gained scientific attention in the 1930s with Dr. Temple Fay, who used ice baths and open windows to lower patients' temperatures, primarily for traumatic brain injuries. In the 1950s, Dr. Peter Safar experimented with hypothermia in the ER to reduce tissue damage in stroke and cardiac arrest patients. Despite early controversy due to unethical experiments during World War II, therapeutic hypothermia is now used in various medical situations, including treating infants with a lack of blood flow to the brain.

    • Nazi experiments on hypothermia and its scientific significanceThe Nazi experiments on hypothermia, while historically significant, were scientifically unreliable. However, the idea that hypothermia could preserve life was later validated by scientists like James Lovelock, leading to its exploration in space travel and the famous case of a woman surviving under ice.

      The data from Nazi experiments on hypothermia, while historically significant, was scientifically unreliable due to poor record keeping and protocols. However, the idea that hypothermia could preserve life instead of causing death was later explored and validated by scientists like James Lovelock, who successfully revived frozen animals. This discovery challenged the common belief that being in a state of hypothermia meant being dead, and instead, opened up possibilities for using hypothermia as a means of preserving life in extreme situations. NASA also investigated hypothermia during the space race, with the goal of protecting astronauts from cosmic rays and the possibility of freezing them for long space journeys. The discovery of the preservative effects of hypothermia was a significant breakthrough, as evidenced by the famous case of a woman who survived after being trapped under ice for 80 minutes.

    • Exploring the complexities of medical hypothermiaMedical hypothermia is a delicate process with risks of rapid warming and is still in its early stages, while Zigazoo is a safe social media network for kids, Squarespace's Fluid Engine simplifies website creation, and Betterment automates savings and investing.

      Medical hypothermia, or intentionally lowering body temperature to save a life, is a complex and delicate process. While the concept makes intuitive sense, the fine-tuning and execution are still a mystery and a challenge for even the most brilliant doctors. Rapid warming after cooling can be just as dangerous as the initial cold exposure. This technique, while potentially lifesaving, is still in its nascent stages and carries significant risk. Elsewhere in the discussion, there was a mention of Zigazoo, a social media network for kids that is safe, human-moderated, and focused on fun. The speakers also talked about Squarespace and its new Fluid Engine website design system, which makes it easier than ever for anyone to create and customize a website. Lastly, Betterment, an automated investing and savings app, was introduced as a way to make your money work for you while you relax. In summary, the discussion touched on the complexities of medical hypothermia, the benefits of Zigazoo for kids' social media use, and the ease of creating a professional website with Squarespace, as well as the potential of Betterment to help grow your savings.

    • Lowering body temperature for improved survivalTherapeutic hypothermia is a technique to reduce body temperature for better outcomes during and after surgery, saving oxygen and energy, and applicable to various conditions like strokes and cardiac arrests.

      Therapeutic hypothermia is a medical technique used to lower body temperature to improve survival chances during and after surgery. By reducing the metabolic rate and energy demand, the body's processes are slowed down, requiring less oxygen and blood flow. This technique can be applied using ice packs, cold blankets, or chilled saline infusions. Its applications include preventing further damage from incidents like strokes or cardiac arrests and extending operating time in surgeries where the heart and lungs cannot be stopped. This method has revolutionized certain surgeries, such as open heart surgery, by allowing doctors to perform procedures on the heart and lungs while they are stopped, using a heart-lung machine. However, there are challenges associated with this technique, such as the potential damage to the blood as it passes through the machine.

    • Using hypothermia to buy time during a heart attackHypothermia can extend the time for successful intervention during a heart attack, reducing brain damage by limiting oxygen use and neurotransmitter release

      During a heart attack, the brain's lack of blood flow can lead to irreversible damage and even death. Medically induced hypothermia can help extend the time between a heart attack and irreversible brain damage, increasing the chances for successful intervention and recovery. This process, also known as return of spontaneous circulation (ROSC), can keep the heart pumping and the body alive, but if consciousness doesn't return, brain damage may be a concern. In such cases, hypothermia can be used to buy time and reduce the amount of oxygen the brain needs, limiting the damage caused by anaerobic respiration and the subsequent release of excess neurotransmitters like glutamate. However, it's important to note that only a small percentage of cardiac arrests outside of a hospital result in survival without brain damage.

    • Protecting the Brain During a Heart Attack and Fostering Positive Online ExperiencesApplying cold temperatures and inducing hypothermia during a heart attack can help prevent further brain damage. Social media platform Zigazoo offers a safe and enjoyable online experience for kids. Nice CX1 offers a scalable and flexible customer experience platform for businesses. Hosting on Airbnb can generate extra income by renting out unused space.

      During a heart attack or cardiac arrest, neurons in the brain can be damaged and release harmful substances, leading to further damage and inflammation. This process can continue for hours and days, causing significant harm. However, applying cold temperatures and inducing hypothermia can help stop this process and give the brain time to rebuild itself. Meanwhile, in a completely different context, social media platform Zigazoo offers a safe and fun environment for kids to share content and interact with friends. It's human-moderated and free of bots, trolls, and AI, making it a positive and enjoyable experience. In the business world, Nice CX1 offers a complete customer experience cloud platform that enables faster resolutions and improved customer satisfaction. It's scalable and flexible, allowing organizations of all sizes to create extraordinary customer experiences and hit key business metrics. Lastly, hosting on Airbnb can provide an opportunity to earn extra income by renting out a spare room or an entire property during events or tourist seasons. It's an easy and profitable way to make the most of unused space.

    • Cooling down and warming up the body in therapeutic hypothermiaDuring therapeutic hypothermia, the body is cooled down during induction, kept at a low temperature during maintenance, and warmed up slowly during re-warming to prevent cell damage and blood clots.

      Therapeutic hypothermia, a medical intervention used to reduce body temperature, consists of three stages: induction, maintenance, and re-warming. Induction involves sedating the patient to prevent shivering, which can interfere with the cooling process, and cooling down the body using methods such as ice packs or invasive techniques like chilled saline solutions. The maintenance phase focuses on keeping the patient at a consistent low temperature, and the re-warming phase must be done extremely slowly to prevent ice crystals from forming and causing cell damage, as well as to avoid the formation of potentially deadly blood clots. Throughout the entire process, close monitoring and careful attention are crucial to ensure the patient's safety.

    • Animals adapt to hibernation by managing their blood cellsAnimals store white blood cells during hibernation to reduce complications and prepare by gorging on food for energy

      Animals, particularly hibernators, have unique abilities to manage their blood cells during hibernation. They remove white blood cells from their bloodstream and store them in lymph nodes, only for them to reappear shortly after hibernation ends. This adaptation helps reduce the risk of post-warming complications like swelling and brain damage. Additionally, animals prepare for hibernation by gorging on food and becoming obese, which their bodies use as energy during hibernation. Humans, on the other hand, do not naturally hibernate, and if we could understand and replicate these abilities, it could lead to significant advancements in medicine, such as longer-lasting blood transfusions and organ transplants, as well as potential treatments for conditions like Alzheimer's disease.

    • The potential for human hibernationA Japanese man survived 24 days in a hibernation-like state, sparking interest in medical applications and space exploration

      The ability to hibernate or enter a state of torpor, which has long been thought to be unique to certain animals, may be present in humans to some extent. This was highlighted by the case of Mitsutake Yuchi Koshi, a Japanese man who survived for 24 days in a state of hibernation after falling and hitting his head in the cold. This discovery has sparked interest in the potential medical applications of suspended animation, such as preserving patients during wartime or during complex surgeries. NASA had previously explored this concept, but the research was later taken up by the U.S. army. The idea is that by freezing a person, doctors could buy themselves time to treat injuries or stabilize patients, much like in science fiction depictions of suspended animation. This could be particularly useful in chaotic battlefield situations, where saving every life is a priority. The potential for human hibernation also raises questions about our evolutionary connections to other primates, such as lemurs, which can hibernate. Overall, the study of hibernation in humans offers exciting possibilities for medical advancements and space exploration.

    • Medically induced hypothermia increases survival and reduces brain damageLowering body temperature during surgery enhances chances of survival and minimizes brain damage, despite risks of pneumonia and hyperthermia

      Medically induced hypothermia can significantly increase the chances of survival and reduce brain damage in patients suffering from cardiac arrest or severe trauma. This is achieved by lowering the body temperature to allow for longer surgery time and better healing. A doctor named Sam Tischerman from the University of Pittsburgh is working on a more extreme version called emergency preservation and resuscitation, which involves flushing the body with freezing cold saline solution. This method has been successful in animals but has not yet been tried on humans. While there are risks, such as pneumonia and hyperthermia, the potential benefits are substantial. The challenge lies in obtaining consent from unconscious patients and overcoming skepticism towards the procedure.

    • Therapeutic hypothermia and satire: two powerful toolsTherapeutic hypothermia improves patient outcomes, satire raises awareness and sparks change

      Therapeutic hypothermia, a medical treatment that uses low body temperature to improve patient outcomes, has been proven effective in several studies, increasing the chances of recovery significantly. Regarding satire, it can serve as a release for the populace, allowing them to express their anger towards leadership without forcing change. However, satire also has the potential to plant the seed of dissent and eventually spark change by raising awareness of leaders' foibles. Chelsea, a listener from Ireland, shared her perspective that satire can be a powerful tool for change by opening people's eyes to the ridiculousness and danger of certain actions. Overall, both therapeutic hypothermia and satire have significant impacts in their respective fields. For more information on therapeutic hypothermia, check out the Stuff You Should Know podcast episode on the topic. And if you have thoughts or theories on satire or anything else, feel free to reach out to the podcast via social media or email.

    Recent Episodes from Stuff You Should Know

    Selects: How Restaurant Health Inspections Work

    Selects: How Restaurant Health Inspections Work

    If you've ever worked in a restaurant, you know the feeling that occurs when the health inspector pays a visit. While nerve wracking, it's the best insurance patrons have that their food will be prepared and served in a proper environment. Learn all about how these inspections work, from their past history to current incarnation, in this classic episode.

    See omnystudio.com/listener for privacy information.

    Stuff You Should Know
    enJune 29, 2024

    Whistling!

    Whistling!

    Whistling is pretty cool when you think about it because it can mean many things, from simple happy tunes to legit communication. Learn all about this ubiquitous skill today. 

    See omnystudio.com/listener for privacy information.

    Stuff You Should Know
    enJune 25, 2024

    The Big Episode on Wikipedia

    The Big Episode on Wikipedia

    Wikipedia changed the world. Before it came along, you had to go to the library to get the answers you sought. And you and your friends had to just agree to disagree on facts. And as the internet grew and commercialized, Wikipedia remains free and open.

    See omnystudio.com/listener for privacy information.

    Stuff You Should Know
    enJune 20, 2024

    Related Episodes

    When to Stop Resuscitation in Critical Care: Patricia Gerritsen

    When to Stop Resuscitation in Critical Care: Patricia Gerritsen

    How do you diagnose death? In Critical Care we deal with death on a regular basis and although it seems black and white, that is often far from the truth.

    Patricia Gerritsen discusses what it means to be dead and how that knowledge can aid you in stopping a resuscitation effort.

    Patricia presents the degrees of death in her eyes as:

    1. Soon to be dead
    2. Reversibly dead
    3. Irreversibly dead
    4. Reversibly, irreversibly dead

    Changes occur following death that can be proof of death. But not always. Pallor mortis, algor mortis, rigor mortis, livor mortis and decomposition can all indicate someone has died.

    There are other clues that can indicate a person is either dead or will soon be dead – with minimal chance of any life saving intervention. The varying ways death presents itself poses a challenge for the clinician. This is especially true when deciding when to stop a resuscitation effort.

    Consider the reversibly, irreversibly dead – also known as the Lazarus phenomenon. These patients achieve return of spontaneous circulation AFTER the resuscitation effort has been stopped. There are over 50 cases in the literature, with a wide and unpredictable array of clinical situations.

    Therefore, the question becomes - what are the limits that can be survived? Patricia suggests that we must know the extreme limits in order to make an educated decision about resuscitation.

    Patricia details some of the most extreme stories of survival in the literature. Submersion has been survived after 66 minutes in a child. An individual survived being in an ice stream after 40 minutes, with a recorded temperature of 13.7 degrees. A man with a potassium of 14 mmol/L made a good recovery.

    There is a case of someone with a pH of 6.33 recovery fully and someone surviving a CO2 level of 375mmHg.

    Patricia highlights these extreme examples to show what is possible whilst acknowledging the decision to stop resuscitation is a difficult and nuanced one.

    When to Stop Resuscitation in Critical Care: Patricia Gerritsen

    For more like this, head to our podcast page. #CodaPodcast

     

    "I'm not dead" - Patricia Gerritsen

    "I'm not dead" - Patricia Gerritsen

    In Critical Care we deal with death on a regular basis and although it seems an ‘on or off’ issue where you are either dead or you are not, nothing is more true. Not only physicians but scientists, philosophers, writers and theologians have been debating about the subject for as long as we have become aware of the concept of death.
    To try to create order from chaos I divide the deceased in 5 categories:
    The soon to be dead,
    The reversibly dead,
    The irreversibly dead
    The walking dead (although this group I will leave to Hollywood to educate us about)
    and the most curious group
    The reversibly, irreversibly dead.
    They are the patients of whom we think they are irreversibly dead, we stop our resuscitation efforts, and then they have return of spontaneous circulation. This is known as the Lazarus phenomenon and although many case reports have been published about this phenomenon over the years, presumably it’s only the tip of the iceberg.
    In providing Critical Care we sometimes need to make immediate decisions on who’s dead and who’s not. Yet decisions about whether further treatment of patients is futile or not can only be made when one is aware of the limits of extremes in physiology that are survivable. Although not every patient should be treated up to these physiological limits, knowing these extremes can help in making an informed decision of whether to continue treatment.

    Ep. 630: The Eagle and The Dragon: A Story of Strength and Reinvention | Chris Duffin

    Ep. 630: The Eagle and The Dragon: A Story of Strength and Reinvention | Chris Duffin
    5-31-21 Allen Cardoza Interviews Chris Duffin

    https://christopherduffin.com/
    http://answers.network

    The world may know Chris Duffin as "The Mad Scientist of Strength", but you wouldn't have ever guessed that if you saw the scrawny kid skinning rattlesnakes and chasing dragonflies in the early '80s. The story of his unconventional life will take you from gripping tales of murder, trauma, heartbreak, and survival deep in the Pacific Northwest wilderness all the way to an idealization of the self-made man--still flawed, but never broken.

    In The Eagle and the Dragon, you'll follow one man's journey into the darkness of his own heart and witness the transformation of alcoholism, pain, and defeat into vision, character, and victory. Through Chris's powerful self-realization, you'll see how the human spirit can be either shackled by circumstance or freed from it. Are you ready to walk through the fire and make your vision a reality?