Logo
    Search

    Podcast Summary

    • Connecting with communities and utilizing technologyBuilding strong community bonds and utilizing AI can enhance our lives and prepare us for the future. Connect with neighbors, explore podcast ideas, and learn about neuroplasticity.

      Building strong community connections and utilizing technology, particularly artificial intelligence, can significantly improve our lives and prepare us for the future. Dr. Laurie Santos introduced Neighbor to Neighbor, a California volunteers network, emphasizing the importance of connecting with neighbors for social bonds and emergency preparedness. Meanwhile, the Technically Speaking podcast, hosted by Graham Klass, explores how AI is revolutionizing various industries and transforming our world. Additionally, the Black Effect Podcast Festival offers an opportunity to pitch podcast ideas and Nissan supports this adventure. In the realm of technology and brain development, neuroplasticity, the ability to adapt the brain, is a topic of great interest. As discussed in the Stuff to Blow Your Mind podcast, neuroplasticity allows adults to learn new skills as effectively as children, but it's essential to remember the importance of neuro stability as we grow older. Overall, connecting with our communities and utilizing technology can lead to personal growth and a better future.

    • Neuroplasticity: The human brain's ability to adapt and learnNeuroplasticity allows us to learn and adapt, but too much malleability can hinder efficiency. Early childhood experiences shape our brains and influence language, social norms, and cultural understanding.

      Neuroplasticity is a crucial aspect of the human brain, allowing us to adapt and thrive in various environments and learn new skills, particularly during critical periods of early childhood. This ability sets humans apart from other animals, as we can adapt to diverse conditions and tasks. However, it's essential to remember that our brains also need stability to function effectively. While neuroplasticity enables us to learn and change, having a brain that is too malleable might hinder our ability to perform tasks efficiently and consistently. The discussion also highlighted the importance of early childhood experiences in shaping our brains and influencing our language acquisition, social norms, and cultural understanding. These factors have contributed significantly to the diversity and success of the human species.

    • Childhood Neuroplasticity and PruningThough our brains prune back some neural connections during development, scientists investigate methods to reintroduce neuroplasticity in adulthood for therapeutic purposes and cognitive enhancement.

      While our neural circuitry branches out extensively during childhood to learn new skills, it eventually prunes back some connections based on our individual needs and potentials. This process, known as neuroplasticity, allows us to specialize and grow, but as we age, the window for significant neural changes narrows. However, scientists continue to explore ways to reintroduce neuroplasticity in adulthood to treat various conditions and maintain cognitive function. It's essential to remember that neuroplasticity is not an absolute good, and its limitations serve a purpose in our development.

    • Exploring the Future of Neuroplasticity-Inducing DrugsExperts believe we can extend critical periods and manipulate them with medication, but groundwork is being laid and specific drugs are yet to be discovered. Neuroplasticity manipulation is a real possibility with potential side effects.

      The future of neuroplasticity-inducing drugs is an unexplored territory with potential pitfalls and exciting possibilities. Experts believe that we will be able to extend critical periods and manipulate them with medication, but the groundwork is still being laid for this development. While we don't yet know what specific drugs might be effective, we can expect that they will have side effects that need to be addressed. The idea of neuroplasticity manipulation is not a distant fantasy but a real possibility, and it's essential to be prepared for it when it happens. In the meantime, we can explore the history of neuroplasticity and the current research being done in this field. Additionally, there are other ways to build meaningful connections in our communities, such as through volunteer networks like Neighbor to Neighbor. And for allergy sufferers, there are fast-acting solutions like Astepro nasal spray to help alleviate symptoms. Overall, it's an exciting time to learn about the potential of neuroplasticity and the advancements being made in various fields.

    • The brain's ability to adapt and changeWilliam James discovered the brain's plasticity, which allows it to change and form new neural pathways in response to external influences like sensory input and habit formation.

      The brain, like the rest of the body, is designed to be adaptable and efficient. Charles Darwin observed that the brains of domesticated animals are smaller than their wild counterparts due to their limited use, reflecting the brain's ability to adapt to environmental circumstances. This concept, known as neuroplasticity, was later explored by William James, who defined it as the brain's ability to change in response to external influences, specifically through the formation and strengthening of neural pathways. James believed that the brain's plasticity is primarily influenced by sensory input and the creation of habits. Overall, the brain's plasticity is crucial for survival and adaptation, whether in a world of scarcity or abundance.

    • Understanding Habits and Brain Plasticity through Early ObservationsEarly scientists like William James, Tanzi, and Ramon y Cajal recognized the role of habits and brain plasticity in shaping our functions and potential. They proposed that habits are linked discharges, complex functions are built from simpler ones, and learning creates associations through synaptic plasticity.

      Our brains form habits and complex functions through the reinforcement of neural pathways. William James, in the late 1800s, had a rudimentary understanding of brain function but made insightful observations about the nature of habits and brain plasticity. He suggested that habits are linked discharges of nerve centers, and complex functions are built from simpler ones in sequence. Moreover, individuals' brain potential and predispositions can change due to repeated interactions with chemicals or sensory data. This idea of brain plasticity, which encompasses various forms of learning and adaptation, is crucial to understanding how our brains adapt and learn. In the late 1800s, scientists like Tanzi and Ramon y Cajal proposed that learning and creating associations between things is due to the strengthening of connections between neurons through repetition. This strengthening process, called synaptic plasticity, is the basis for learning and memory.

    • The Evolution of Our Understanding of Brain PlasticityOur understanding of brain plasticity, the ability for the brain to adapt and learn, has evolved significantly over time, with ongoing research highlighting its importance for learning and adaptation throughout our lives.

      Our understanding of how the brain learns and adapts, specifically through the synaptic model of plasticity, has evolved significantly over time. This concept, which can be thought of as linking specific experiences or actions to corresponding responses, was first widely accepted in the early 20th century but faced competition from other theories. However, it was rehabilitated in the late 1940s by scientists like Jerzy Konorski and Donald Hebb, and later supported by extensive experimental evidence. Despite this, there is still debate about the extent of plasticity in the adult human brain, particularly in regards to language acquisition and music learning, where children exhibit greater abilities than adults. For instance, the skill of perfect pitch is believed to be nearly impossible to acquire after the age of six. While this information may seem daunting, it underscores the importance of continued research into the brain's plasticity and the potential for learning and adaptation throughout our lives.

    • Exploring ways to make adult brain more adaptable using psychedelicsResearch into using psychedelics to expand neural circuits in adults for conditions like depression, anxiety, and PTSD is ongoing. While some promising results have been found in animal studies, more research is needed to understand safety and effectiveness in humans.

      Researchers are exploring ways to make the adult brain more adaptable and learnable, similar to a child's brain, through the concept of induced neuroplasticity. While there have been promising results in animal studies using drugs like psychedelics, more research is needed to understand how to effectively and safely apply these findings to humans. The ultimate goal is to develop prescription drugs that can expand neural circuits observed to atrophy during conditions like depression, anxiety, and PTSD. The UC Davis study found that certain psychedelic compounds, such as DOI, DMT, and LSD, make neurons more likely to branch out and develop. However, more research is required to fully understand the implications and potential side effects of these compounds in humans.

    • Exploring the potential for induced neuroplasticity in adultsRecent research suggests psychedelics may induce neuroplasticity, but more study is needed. Another approach involves inhibiting HDAC to potentially reopen the window of neuroplasticity in adults, but its effectiveness is unknown.

      Recent research suggests that psychedelic substances may hold the key to inducing neuroplasticity, a process that allows the brain to form new neural connections. However, the researchers stress that this is a complex area of study and there's still much to learn. They also caution against trying to replicate the effects of psychedelics with these substances, as they are not yet ready for prime time. Another area of research involves inhibiting the enzyme HDAC, which is believed to close the window of neuroplasticity in children, to potentially reopen it in adults. This approach, using a drug like valproate, has shown promise in animal studies, but its effectiveness in humans is yet to be determined. Overall, while the potential for induced neuroplasticity in adults is an exciting area of research, it's important to approach it with caution and to continue to explore the complexities of the brain.

    • Study suggests drug may aid in identifying musical tonesA small study found that valproate could potentially help individuals without perfect pitch or musical training identify musical tones, but more research is needed before drawing conclusions. Proceed with caution when considering drugs to induce neuroplasticity.

      A small study suggested that the drug valproate may enhance the ability of individuals without perfect pitch or musical training to identify absolute musical tones by name, compared to a placebo group. However, it's important to note that this is a small study with potential limitations, and more research is needed before drawing definitive conclusions. Additionally, while there are ongoing trials exploring the potential of drugs like Donepezil and Prozac to induce neuroplasticity, it's crucial to approach such interventions with caution and consideration for the potential downsides and long-term consequences. The brain's natural developmental processes may shut down for a reason, and we should proceed with caution before attempting to manipulate them.

    • Neuroplasticity in Adulthood: Risks and RewardsNeuroplasticity's benefits in childhood extend to adulthood, but potential risks include misuse, abuse, and links to conditions like savant syndrome or autism. Consider the costs and consequences before manipulating it.

      While neuroplasticity, the brain's ability to adapt and change, can bring numerous benefits, especially in childhood, extending it into adulthood may not be without risks. The potential downsides include the possibility of misuse or abuse, as well as the potential link between excessive plasticity and conditions such as savant syndrome or autism. It's important to consider the potential costs and consequences of manipulating neuroplasticity, even for therapeutic purposes. Additionally, Nissan is offering a chance for podcasters to pitch their ideas at the Black Effect Podcast Network. The company continues to support the next generation and add excitement to people's lives.

    • Exploring the delicate balance of neuroplasticityFocus on safe practices for enhancing neuroplasticity, like getting enough sleep, exercise, nutrition, intellectual and social stimulation, and avoiding quick-fix solutions.

      The brain's neuroplasticity, or its ability to change and adapt, is a delicate balance that can be influenced by various factors, including genetics and environmental stimuli. Some research suggests that individuals with certain conditions, such as autism and schizophrenia, may be more susceptible to these influences. While neuroplasticity-enhancing drugs could hold great promise for helping people, there is a risk of unintended consequences and potential abuse. Instead, focusing on safe practices like getting enough sleep, exercise, and nutrition, using your brain through intellectual and social stimulation, and avoiding quick-fix solutions, can have positive effects on brain health over a lifetime.

    • Understanding the potential benefits and risks of neuroplasticity treatments and medicationsApproach neuroplasticity with a nuanced understanding and healthy skepticism, while also building connections and embracing financial transparency.

      While the future of neuroplasticity treatments and medications holds great promise, it's important to understand their potential benefits and risks. Reductionist attitudes that trivialize mental health issues and dismiss the need for medication do a disservice to those struggling. Instead, we should approach neuroplasticity with a nuanced understanding and a healthy dose of skepticism. In the meantime, building meaningful connections in our communities through initiatives like Neighbor to Neighbor can help us navigate the uncertainties of life. And for those seeking financial freedom, learning to unlearn outdated financial wisdom and embracing transparent wireless plans like Visible can help pave the way.

    Recent Episodes from Stuff To Blow Your Mind

    Smart Talks with IBM: AI & the Productivity Paradox

    Smart Talks with IBM: AI & the Productivity Paradox

    In a rapidly evolving world, we need to balance the fear surrounding AI and its role in the workplace with its potential to drive productivity growth. In this special live episode of Smart Talks with IBM, Malcolm Gladwell is joined onstage by Rob Thomas, senior vice president of software and chief commercial officer at IBM, during NY Tech Week. They discuss “the productivity paradox,” the importance of open-source AI, and a future where AI will touch every industry.

    This is a paid advertisement from IBM. The conversations on this podcast don't necessarily represent IBM's positions, strategies or opinions.

    Visit us at ibm.com/smarttalks

    See omnystudio.com/listener for privacy information.

    Weirdhouse Cinema: The Dungeonmaster

    Weirdhouse Cinema: The Dungeonmaster

    In this episode of Weirdhouse Cinema, Rob and Joe return to the glorious world of 80s Charles Band productions with 1984’s “The Dungeonmaster,” a supernatural dreamscape with eight directors starring Jeffrey Byron, Richard Moll and Leslie Wing. It’s time to reject the devil’s reality and substitute your own! 

    See omnystudio.com/listener for privacy information.

    New Season of Smart Talks with IBM Coming Soon

    New Season of Smart Talks with IBM Coming Soon

    Smart Talks with IBM returns with a new season on Tuesday, June 25th. This season, we’re diving back into the world of artificial intelligence, but with a focus on the powerful concept of “open,” and how it applies to AI. Host Malcolm Gladwell will invite curious colleagues from Pushkin Industries to explore how openness is already reshaping industries, ways of doing business, and our very notion of what's possible.

    This is a paid advertisement from IBM.

    Visit us at ibm.com/smarttalks

    See omnystudio.com/listener for privacy information.

    From the Vault: Dreamfall into the Dark, Part 4

    From the Vault: Dreamfall into the Dark, Part 4

    The wonders and terrors of the dreaming mind do not always flee completely with the dawn. At certain times and places in history, it seems that dreams suddenly ascend to new heights of cultural fascination. In this Stuff to Blow Your Mind series, Robert and Joe explore periods when the eye of culture fixes on the dream world. (originally published 6/27/2023)

    See omnystudio.com/listener for privacy information.

    Related Episodes

    The Scientist and the Shaman: Hallucination

    The Scientist and the Shaman: Hallucination

    In this classic episode of Stuff to Blow Your Mind, Julie and Robert continue their discussion of the overlap between shamanism and cognitive neuroscience. In particular, what sort of hallucinatory experiences do substances like DMT, psilocybin and salvia grant users? Why do humans have trace elements of DMT in their bodies? All these questions and more will be discussed.

    Learn more about your ad-choices at https://www.iheartpodcastnetwork.com

    See omnystudio.com/listener for privacy information.

    Acid Flashbacks

    Acid Flashbacks

    Acid Flashbacks: Are acid flashbacks real or are they merely a ghost story of psychedelic culture or anti-drug messaging? In this episode of Stuff to Blow Your Mind, Robert and Julie discuss the misconceptions as well as the real science of Hallucinogen Persisting Perception Disorder or HPPD. Image credit: David Crausby/Flick/Getty

    Learn more about your ad-choices at https://www.iheartpodcastnetwork.com

    See omnystudio.com/listener for privacy information.

    From Jumping Spiders to Silicon: Neuroscience and the Future of Computing - Intel on AI Season 3, Episode 1

    From Jumping Spiders to Silicon: Neuroscience and the Future of Computing - Intel on AI Season 3, Episode 1

    In this episode of Intel on AI host Amir Khosrowshahi and Bruno Olshausen talk about neuroscience and the future of computing. Bruno is a professor at Berkeley with appointments in the Helen Wills Neuroscience Institute and School of Optometry. He is also the director of the Redwood center for Theoretical Neuroscience, which brings the fields of physics, mathematics, engineering, and neuroscience together to study how networks of neurons in the brain process information.

    In the episode, Bruno and Amir discuss research about recording large populations of neurons, hyperdimensional computing, and discovering new types of engineering principles. Bruno talks about how in order to understand intelligence and its underpinnings, we have to understand the origins of intelligence and perceptual psychology outside of mammalian brains. He points to the sophisticated visual system of jumping spiders as inspiration for developing systems that use low energy in a small form factor. By better understanding the origins of perception and other biophysical structures, Bruno theorizes the artificial intelligence field may evolve beyond image recognition tasks of current neural networks. Bruno and Amir close the episode by talking about the elementary units of computation, the idea of “listening to silicon” as proposed by Carver Mead, neuromorphic computing, and what the future of research might hold.

    Academic research discussed in the podcast episode:

    PTSD, Meet MDMA

    PTSD, Meet MDMA

    Rachel Yehuda, PhD, has been at the forefront of trauma research and treatment for three decades. Her pioneering work with populations including military veterans and Holocaust survivors has illuminated the biology of post-traumatic stress disorder (PTSD). Despite scientific advances, PTSD remains difficult to treat. Even “gold standard” cognitive-behavior approaches are ineffective for too many patients. In this interview, Dr. Yehuda talks about the therapeutic potential of psychedelic-assisted psychotherapy and describes her journey from skeptic to advocate for more research.

    Dr. Yehuda is Professor of Psychiatry and Neuroscience, and Director of The Center for Psychedelic Psychotherapy and Trauma Research at the Icahn School of Medicine at Mount Sinai. She is also the Vice Chair for Veterans Affairs in the Department of Psychiatry as well as Director of the Traumatic Stress Studies Division.

    Links

    Visit https://www.mountsinai.org/clinical-trials to see if you're eligible to enroll in a clinical trial with the Mount Sinai Health System.

    Check out more episodes of Road to Resilience —as well as guest pictures, transcripts, and more— on the Mount Sinai website.

    Road to Resilience brings you stories and insights to help you thrive in a challenging world. From fighting burnout and trauma to building resilient families, we explore what’s possible when science meets the human spirit.

    The Absolute Best Ways To Change Your Brain! Scientifically Proven Guide To Improve Your Brain with Dr. Michael Merzenich

    The Absolute Best Ways To Change Your Brain! Scientifically Proven Guide To Improve Your Brain with Dr. Michael Merzenich

    If you’ve ever wanted a stronger, smarter, sharper mind, and at any age, then do we have the Soft-Wired show for you!

     

    Today I’ll be talking with Dr. Michael Merzenich the undisputed heavyweight and father of brain plasticity, award winning neuroscientist, the co-founder and chief scientific officer of Posit-Science, and the author of a brilliant book on changing your mind, Soft-Wired.

     

    We'll talk all about how the new science of brain plasticity can change your life, and how do use it for happiness, success, and longevity.

     

    Topics Include:

    1. What is brain plasticity?
    2. Can we truly change our brains?
    3. What in the world is going on with our brains?
    4. What is the latest science suggesting?
    5. How do we begin to change our brains?
    6. Are there any limits?
    7. What’s the importance of challenges?
    8. What’s the importance of getting uncomfortable?
    9. What does our “landscape” have to do with the brain?
    10. What’s the importance of nature when it comes to the mind?
    11. What’s the importance of presence – and what does it mean to truly observe the world around you?
    12. What does positivity have to do with the brain?
    13. How can helping your brain, help your mood?
    14. What brain challenges are our children facing today?
    15. What are brain games and how can they help?
    16. How often do you need to play brain games to see results?
    17. Can you change your brain without diet and exercise?
    18. What simple lifestyle changes are needed to change the brain?
    19. How can changing our brains affect our entire lives?
    20. What are the most important changes to begin making?
    21. What are the simplest changes to take beginning today?

     

    Visit: https://www.positscience.com/ & https://www.michaelmerzenich.com/ 

     

    To find out more visit:

    …….

    Follow Michael and Jessica’s exciting journey and get even more great tools, tips, and behind-the-scenes access. Go to https://www.patreon.com/inspirenation  

    For free meditations, weekly tips, stories, and similar shows visit: https://inspirenationshow.com/  

    We’ve got NEW Merch! - https://teespring.com/stores/inspire-nation-store  

    Follow Inspire Nation, and the lives of Michael and Jessica, on Instagram - https://www.instagram.com/InspireNationLive/  

    Find us on TikTok - https://www.tiktok.com/@inspirenationshow