The Metabolomist - Jan Krumsiek

In this episode, Alice Limonciel and Haley Chatelaine discuss the benefits of using metabolomics to study multiple diseases, the fascinating world of fat-soluble vitamins and their absorption in patients with metabolic syndrome. This episode was created in collaboration with the Early Career Members (ECM) of the Metabolomics Association of North America (MANA) and begins with a conversation about life as an early career scientist with Arpana Vaniya and Nicole Prince, who are restively chair and vice-chair of MANA-ECM.

In this episode, Alice Limonciel and Sapna Sharma discuss how to make the most of the omic data already generated in cohort studies, the place of metabolomics in multi-omics strategies, and how to go beyond associations and towards causal relationships and their implications for medicine.

In this episode, Alice Limonciel and Karel Kalecký discuss what to look out for when planning a metabolomics experiment with brain tissue samples from biobanks, what characterizes Parkinson’s and Alzheimer’s disease at the metabolic level, and his experience navigating biological interpretation as a computer scientist turned metabolomist.

In this episode, Alice Limonciel and Gary Patti discuss the applications of flux metabolomics to the study of cancer, the benefits of various biological models, and the potential of nutritional intervention to study and influence cancer metabolism.

In this episode, Alice Limonciel and Rachel Kelly discuss the relevance of metabolomics to the field of epidemiology, the challenges in combining metabolomic studies for large meta-analyses, and the application of metabolomics to create metabotypes of asthma.

In this episode, Alice Limonciel and Jennifer Kirwan talk about what stands in the way of new applications of metabolomics in the clinics, the importance of quality assurance and quality control (QA/QC), and how this can affect your experiments all the way to the interpretation of the biology.

In this episode, Alice and David Wishart talk about the many ways that clinical practice and clinical research will benefit from a broader application of metabolomics, how databases support the metabolomics field, and why we need to keep developing better tools to support data analysis and interpretation.

In this episode, Alice and Robert Ahrends talk about the importance of standardization and quantification in lipidomics, how to analyze and interpret lipidomic datasets, and how lipids are much more that structural or energy storage molecules.

In this episode, Alice talks to Prof. emer. Hannelore Daniel about the joint evolution of nutrition research and omics, common misconceptions about the microbiome, and the influence of diet and exercise on the metabolome.

In this episode, Alice talks to Prof. Karsten Suhre about the added value of combining genomics with metabolomics, tips and tricks to find confounders, and the power of computing metabolite ratios.