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    Using Caffeine to Optimize Mental & Physical Performance

    enDecember 05, 2022
    What are the main benefits of caffeine?
    How should caffeine be used for maximum alertness?
    What is the recommended dosage of theanine with caffeine?
    Why should new caffeine users be cautious?
    What effects do caffeine and theanine have on sleep?

    • Unveiling the Positive Health Benefits & Tools of Caffeine ConsumptionUnderstanding how caffeine works at a mechanistic level can help us use it to our advantage or avoid it when needed.

      Caffeine is a powerful substance used by many people around the world.It can increase alertness and reduce feelings of sleepiness and fatigue.What most don't know is that it can also increase our liking of certain foods and drinks.In this episode of the Huberman Lab podcast, we learn about the positive health benefits of caffeine, as well as when to avoid it.Knowing how caffeine works at a mechanistic level, can help us to use it to our advantage or avoid it when needed.We will also learn about tools to help us make better decisions.This episode promises to be full of useful information for understanding caffeine and how to use it.

    • Can Yerba Maté Tea Help You Lose Weight?Yerba maté tea contains GLP-1 which reduces hunger at the level of the brain and body and stimulates thermogenesis which increases your basal metabolic rate, making you burn more calories even at rest.

      Yerba maté tea has been found to be a great tool for weight loss, mental and physical health, and performance.It contains the molecule GLP-1 which is found in the brain and body and reduces hunger in two ways.By activating certain neurons in the hypothalamus, it makes us feel full at the level of the brain, and it acts directly on the gut to give us a slight sense of fullness.It was originally discovered in Gila Monsters who can go long periods of time without ingesting anything due to the large amounts of GLP-1 they produce.Yerba maté tea also stimulates GLP-1 release and has been proven to be effective for weight loss.It blunts appetite both at the level of the brain and body, but also stimulates thermogenesis which increases our basal metabolic rate, making us burn more calories even at rest.Drinking yerba maté tea or doing fasted exercise are both good ways to stimulate GLP-1 release, and there are also prescription GLP-1 analogues available for more robust activation.

    • Harnessing the Power of Caffeine for Improved PerformanceCaffeine can be an effective tool for improving performance, both physically and mentally, due to its ability to increase neuromodulators, reaction time, and stimulate neural circuits associated with learning and memory.

      Caffeine is a widely used and regularly consumed substance that is often associated with negative connotations like addiction.However, it has been scientifically proven to have numerous benefits for both physical and mental performance.It increases neuromodulators such as dopamine and norepinephrine, which can improve alertness, motivation and drive, and may even have some antidepressant effects.Caffeine also increases reaction time and stimulates the neural circuits in the brain associated with learning and memory, making it an effective way to enhance performance.This makes it a powerful tool to have in one's arsenal when it comes to improving productivity.

    • The Power of Caffeine: A Boost of ReinforcementCaffeine can act as a powerful reinforcer, even without its taste being noticed, as it can subconsciously become a preferred taste.

      Caffeine has been found to act as a powerful reinforcer in both humans and animals.It is found in small concentrations in plants, often masked by other flavors.A recent study showed that bees were more likely to prefer caffeine containing nectars, not because of the taste, but because of the energy boost it provided.This energy boost made them more alert and able to do more work.Caffeine can act subconsciously, so even though it tastes bitter at first, it quickly becomes a preferred taste.It can even reinforce the mug you are drinking out of or the person you are with when you consume it.

    • Unveiling the Stimulating Effects of CaffeineCaffeine has the ability to increase alertness, reward pathways, and probability of returning to certain activities, making it a powerful stimulant.

      Caffeine is a stimulant that affects our brain chemistry in different ways.It stimulates the release of dopamine and acetylcholine, two neurochemicals associated with alertness and well-being.Caffeine also enhances the reward pathways of the brain, associated with activities like sex and food.This means that dopamine released in response to positive experiences is more likely to be received and produce feelings of drive and excitement.Caffeine also acts as a reinforcing agent, increasing the probability that we'll return to certain activities, and as an antagonist to adenosine, offsetting the sleepiness we'd otherwise feel.All of these effects can help us better think, adjust our strategies, and stay alert.

    • The Unconscious Effects of CaffeineCaffeine can have an effect on your body without you even realising it.

      Caffeine can have both positive and negative effects on the body.It acts as a reinforcing agent, making us feel slightly better or a lot better after consumption, making us seek out and enjoy the taste of caffeine-containing beverages.It also increases the release of dopamine and acetylcholine, which increases clarity of thought, and increases the number of dopamine receptors in the reward pathway, amplifying the effects of positive experiences.Caffeine also acts as an adenosine antagonist, reducing feelings of lethargy and fatigue and decreasing the desire to sleep.All of these effects happen without us being consciously aware of them.

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    • Unlocking Increased Energy Production through CaffeineCaffeine can provide temporary energy boosts, but it is essential to manage adenosine levels through sleep, rest, sunlight, and exercise for long-term energy.

      Caffeine is a plant alkaloid that binds to adenosine receptors in the brain and body.This prevents adenosine from breaking down parts of the energy production pathway, which leads to increased energy production.However, this is only temporary, as the caffeine will eventually become dislodged, leading to a backlog of adenosine and extreme sleepiness.Caffeine allows us to have energy at times when our natural circadian cycle would have us feeling tired and to work in shifts, something that was not possible before.To completely clear out adenosine, sleep, short naps, non-sleep deep rest, viewing morning sunlight, and certain forms of exercise can be used.

    • Can Caffeine Enhance Your Mental and Physical Health?Knowing your body weight and the caffeine content of any beverages or foods you consume can help you make informed decisions about your caffeine intake.

      Caffeine is a powerful tool that can be used to enhance mental and physical health, as well as performance.It is important to understand your own body weight in kilograms as this will help you determine the right dosage of caffeine to ingest.Generally, 1-3 milligrams of caffeine per kilogram of body weight is considered safe and effective, so if you weigh 50 kilograms that would be 50-150 milligrams of caffeine.It is possible to exceed this dosage, however, you should be careful to avoid potential issues such as headaches, anxiety, and irritability.Additionally, drinking caffeine multiple times a day can also cause problems, so it is best to spread out the doses.Finally, it is important to be aware of the caffeine content of any beverages or foods you may consume.Knowing this information can help you make informed decisions about your caffeine intake.

    • Start Your Day Right: Harnessing the Power of Sunlight and Caffeine for Maximum ProductivityTaking advantage of sunlight and caffeine in the morning can lead to increased alertness, focus, and productivity throughout the day.

      Starting the day with bright sunlight and physical exercise, such as jumping jacks or a brisk walk, is a great way to set the body up for a successful day.Delaying caffeine intake for 90-120 minutes after waking further boosts alertness, focus, and energy by allowing the body to wake up naturally and spike cortisol levels.This helps to clear out any residual adenosine in the system and reduces the afternoon crash many people experience.Ingesting caffeine at the right time in the morning can provide better alertness throughout the day, and prevent disruption of nighttime sleep.By employing these tools, you can enjoy a more productive and restful day.

    • Offsetting Afternoon Fatigue with Morning Exercise and Caffeine ConsumptionRegular exercise can be beneficial and can be offset with caffeine consumption in the morning, but caution should be taken for a potential afternoon crash.

      Exercising in the morning and having a delay for caffeine consumption can lead to more wakefulness and better sleep.For those who want to workout in the morning shortly after waking, it is ok to ingest caffeine prior to the exercise.However, it can lead to increased fatigue in the afternoon.Regular exercise is beneficial and can be incorporated into a weekly structure.For those who need caffeine shortly after waking, drinking half of the caffeine right away and the other half an hour later can help offset the afternoon crash.Caffeine has a long lasting effect with a quarter life of 12 hours.

    • Maximizing the Performance-Enhancing Effects of CaffeineConsuming caffeine on an empty stomach and combining it with theanine can increase its performance-enhancing effects while avoiding jitteriness and potential crash.

      By controlling the dosage of caffeine and consuming it on an empty stomach, one can experience the stimulant effect without feeling overly anxious and jittery.To offset the jitteriness, many people opt to take 100 milligrams of theanine.To maximize the performance-enhancing effects of caffeine, it can be helpful to abstain from caffeine for a few days or consume it on an empty stomach.To avoid the jitteriness and potential crash, one should hydrate with something containing a small amount of sodium such as a glass of water with a pinch of salt or an electrolyte drink.Finally, theanine is increasingly being used for its calming effect and can be found in many energy drinks and coffee beverages.

    • Offset Jitteriness with Theanine to Improve Sleep Quality and Reduce Depression/AnxietyTheanine consumption in dosages of 200-400 milligrams can help reduce jitteriness associated with caffeine consumption, while also improving sleep quality and reducing depression and anxiety.

      Taking theanine can help reduce jitteriness associated with caffeine consumption.It is also a nonprotein amino acid found in green tea.Theanine competes for receptors of excitatory neurotransmitters, like glutamate, which can reduce alertness.To offset jitteriness from caffeine, theanine should be taken in dosages of 200 to 400 milligrams.In addition to reducing jitteriness, it can also help reduce depression and anxiety and improve blood vessel function.It can also enhance the quality, depth and duration of sleep, though it should be avoided if one is a sleepwalker.It is important to note that the peak effects of caffeine and theanine occur at different times, so theanine should be taken accordingly.

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    • Enjoying the Benefits of Caffeine - ResponsiblyBe mindful of how much caffeine you are consuming and when, in order to reap the benefits without the risks.

      Caffeine has many effects on our body, both positive and negative.It can increase alertness and physical performance, while also negatively affecting hormone levels and osteoporosis.Studies have found that, when consumed in the appropriate dosage, caffeine can protect against depressive symptoms.However, it is important to keep the anxiety-inducing effects of caffeine in check, as these can lead to further issues.Therefore, it is important to be aware of how much caffeine is consumed and when.This can help ensure that the benefits of caffeine are enjoyed without the risks.

    • Unlocking the Power of Quality SleepCaffeine should be avoided 12 hours prior to bedtime to ensure quality sleep and promote good mental and physical health.

      Sleep is the foundation for our mental and physical health and performance.Getting quality sleep 80% of the nights is a good goal.It's ok to have an occasional afternoon caffeine intake, but it's best to avoid it in the 12 hours prior to sleep.Caffeine has a quarter life of 12 hours, so even if you drink it at noon, 25% of its effects will still be active at midnight, which can disrupt your sleep and emotional processing the following day.Slow-wave sleep is associated with somewhat mundane dreams, but it's also important for growth hormone release, protein synthesis, and immune system function.

    • Unlocking the Performance-Enhancing Effects of CaffeineAbstaining from caffeine for 5 days and then ingesting it 90-120 minutes after waking can maximize alertness-promoting effects, while abstaining for 20 days and taking it 30-60 minutes before physical activity can enhance physical performance.

      Caffeine has been studied for its performance-enhancing effects since the 1930s and is commonly used to improve reaction time, mood, alertness, focus, memory, physical dexterity, power output, endurance and feelings of well-being.Caffeine should be used correctly and the way it is taken is important.For maximum alertness-promoting effects, it is recommended to abstain from caffeine for 5 days and then ingest it 90-120 minutes after waking.For physical performance, it is recommended to abstain from caffeine for 20 days and then take it 30-60 minutes before the physical task.Regular caffeine users should still see performance-enhancing effects, although not as robust as those who abstain.Finally, those not accustomed to caffeine should be careful when ingesting it as it can cause anxiety.

    • Reaching Peak Performance with Caffeine During the Menstrual CycleCaffeine can be a beneficial ergogenic aid for women throughout their menstrual cycle to help reach peak performance.

      Menstrual cycle can have an effect on performance in women.Research suggests that drinking caffeine can be beneficial during all three phases of the menstrual cycle.Caffeine can help improve peak aerobic cycling power.To gain the benefits, women should consume 3 milligrams of caffeine per kilogram of body mass.Caffeine can be an ergogenic aid for women throughout their menstrual cycle, as it can be used to enhance physical performance regardless of the phase.Therefore, women can regularly use caffeine to help them reach their peak performance.

    • Unlocking Memory Retention with CatecholaminesTo enhance memory retention, use caffeine and other techniques before and after studying to increase catecholamine levels.

      Learning something new can be a challenge, but there are some ways to help us remember the material better.Caffeine is one such way.Drinking 1-3 milligrams of caffeine per kilogram of body weight about 30 minutes before studying can help improve focus and alertness.Furthermore, spiking adrenaline levels after learning can also increase memory retention.This can be done through cold exposure or by drinking caffeine.Exercise has also been found to help memory encoding.All of these techniques increase levels of catecholamines, which are neurotransmitters that help the brain remember things.So if you want to remember something better, try using caffeine and other techniques before and after studying.

    • Improve Memory with Caffeine and Naps - Know the LimitsRestricting caffeine intake to the earlier part of the day will maximize the effectiveness of naps for improving memory.

      Caffeine and naps have been shown to be a great way to improve memory for recently learnt information.Instead of popular trend of nappuccino, which is having coffee and then taking a nap, it is better to restrict caffeine intake to the earlier part of the day.This is because the effects of caffeine can reduce the effectiveness of the nap.Also, non-sleep deep rest protocols can be done to improve mood, focus and alertness without the need to have caffeine.These methods can be found online for free.

    • Enhance Your Performance Through Caffeine and Exercise".Caffeine can be a useful tool to improve performance, alertness, focus, and mood while exercising and can even help make exercise more enjoyable.

      Exercising with caffeine can improve your performance, focus and alertness during and after the activity.It can also increase dopamine release, which is beneficial for mood and alertness.Caffeine also acts as a reinforcer, making the experience of exercise more enjoyable and the activities that follow more reinforcing.This can be beneficial for those who don't particularly enjoy exercise and help them to stick with it.Ingesting caffeine alongside certain tastes can also make them more positive.Overall, caffeine can be a very useful tool for enhancing performance.

    • Enhancing Exercise with Caffeine While Avoiding RelianceWhen using caffeine to enhance exercise, be aware of the potential for dopamine levels to drop below baseline and cause a drop in mood.

      Exercise is a great way to increase dopamine and boost mood, alertness, and performance.It is possible to use caffeine before exercise to increase dopamine and create a reinforcing effect to make exercise more enjoyable.However, it is important to not become reliant on combining many stimuli every single time one exercises, as this can lead to dopamine levels dropping below baseline and feeling low after the effect wears off.It is best to occasionally use caffeine before exercise and be mindful of how one is feeling afterwards.If one notices a drop in mood, it is best to wait until that dopamine level returns to baseline before repeating the activity.

    • Unlocking the Positive Effects of Caffeine Through Resistance TrainingTaking advantage of the performance enhancing effects of caffeine requires careful moderation and frequency of consumption.

      Caffeine can be beneficial as it can help with performance but it can also be habit forming.To maximize the positive effects of caffeine it is best to consume it every other day.This schedule avoids the unpleasant side effects of withdrawal that occur if you suddenly stop taking it.It is also suggested to only consume caffeine on days when you are doing resistance training.This way you can take advantage of the performance enhancing effects of caffeine while still avoiding the habit forming effects.It is important to remember that everyone's experience will be different, so it is worth talking to others who have tried this and sharing your own experience.

    • Boost Your Health with Moderate Caffeine IntakeCaffeine can provide many positive health benefits, but should be used in moderation and with consideration for timing in order to support long-term health.

      Caffeine has a variety of positive effects on health and well-being.It increases dopamine levels in the brain, helping with focus and attention, and can reduce the risk of Parkinson's and Alzheimer's-related dementia.It can also provide relief from headaches and asthma.It is important to note that while caffeine can help with these health benefits, it should not be used to replace a healthy sleep schedule as it can disrupt regular rest and ultimately undermine long-term health.Caffeine is a beneficial supplement but should be used in moderation and with consideration for the timing of intake.

    • Leveraging the Effects of Caffeine for Your BenefitWe can use caffeine to increase our appetite for certain things, reduce sugar cravings, increase reinforcement of different foods and experiences, or to avoid reinforcing things we would like to stop.

      Caffeine is an incredibly powerful molecule that affects our brain and body in various ways.It can reduce fatigue and increase focus, alertness, and mood.It can also improve physical performance, increase dopamine and acetylcholine in the forebrain, and act as a powerful reinforcer of things, foods, people, and experiences.We can use caffeine to increase our appetite for certain things, like broccoli, or to reduce sugar cravings.We can also use it to increase reinforcement of different foods and experiences, or to avoid reinforcing things we would like to stop.Understanding the way caffeine works can allow us to leverage these effects in any direction we choose.

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    In this episode, my guest is Dr. Teo Soleymani, M.D., a double-board-certified dermatologist and specialist in skin cancer and reconstructive surgery. We discuss science and clinically supported protocols to improve skin health and give your skin a more youthful appearance and structure, reducing premature aging and skin cancer risk. We discuss the impact of sun exposure on skin appearance and aging and the surprising relationship between sun exposure and skin cancer. We explain how mineral-based (inorganic) sunscreens differ from chemical (organic) sunscreens, whether sunscreen can minimize premature skin aging, reduce cancer risk, and if there are any health risks associated with sunscreen use. We discuss skincare routines to significantly improve skin appearance and how to select skincare products. We discuss how caffeine, nicotine, alcohol, and stress impact the skin and describe how nutrition and anti-inflammatory diets can improve skin health. We also discuss the causes and treatments for common skin conditions, including dandruff, acne, rosacea, eczema, psoriasis, and vitiligo. Our conversation also covers topics such as the use of retinoids, laser treatments, red-light phototherapy, supplements, and how to best monitor for skin cancer. This episode provides numerous actionable protocols, most of which are zero-to-low cost, for improving skin health and appearance, reducing cancer risk, and treating skin problems. Access the full show notes for this episode at hubermanlab.com. Pre-order Andrew's new book, Protocols, at protocolsbook.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman ROKA: https://roka.com/huberman Joovv: https://joovv.com/huberman Helix Sleep: https://helixsleep.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Dr. Teo Soleymani 00:01:35 Sponsors: ROKA, Joovv & Helix Sleep 00:05:45 Skin Turnover; Skin Appearance & Stress  00:13:35 Caffeine, Vasoconstriction & Skin Redness 00:16:31 Nicotine, Vaping & Skin Appearance 00:18:37 Alcohol, Skin Health 00:24:33 Hydration, Fluid Intake & Genetics 00:26:19 Tool: Selecting a Moisturizer 00:29:28 Sponsor: AG1 00:30:40 Puffiness Under Eyes & Cause 00:32:14 Tool: Skin Cleansing; Frequency, Showers 00:41:57 Dry & Flaky Scalp, Dandruff 00:46:09 Cost & Skincare Products 00:50:20 Tool: Sun Exposure & Skin Health, Mood 00:56:24 Sponsor: LMNT 00:57:35 Sunscreens vs. Sunblocks; Mineral-Based (Inorganic) vs. Chemical (Organic) Sunscreen 01:02:45 Physical Barriers, Sunscreens, Oral Supplements & Skin Cancer 01:07:27 Skin Cancer, Genetics; Sunscreen, Premature Aging 01:12:11 Premature Aging & Skincare 00:15:56 Choose Mineral or Chemical Sunscreen? 01:20:24 Polypodium Supplement, Sun Exposure, Skin Redness 01:26:02 Tool: Selecting Mineral-Based Sunscreens 01:28:30 Chemical Sunscreens & Blood-Brain Barrier 01:30:13 Nutrition, Gut Microbiome & Skin Health 01:34:28 Tool: Nutrition for Skin Health, Protein, Anti-Inflammatory; Collagen; Omega-3 01:42:58 Retinoids vs. Retinol, Skin Appearance 01:49:45 Laser Resurfacing; Exfoliation, Microdermabrasion 01:56:52 Red Light Therapy & Phototherapy, Face Masks, Light Panels 02:04:10 Psoriasis, Phototherapy 02:10:03 Vitiligo, Immune System & Skin Cancer Risk 02:15:41 Acne, High Glycemic Index Foods, Dairy 02:19:38 Rosacea, Types & Treatments 02:23:00 Eczema, Immune System 02:25:37 Popping Pimples & Acne Scars; Corticosteroids 02:30:15 Tattoos; Tool: Monitoring for Skin Cancer, Moles, Annual Exams 02:36:28 HPV, Cancer & Warts; Vaccine & Cancer Risk 02:43:31 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures
    Huberman Lab
    enAugust 19, 2024

    Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries

    Perform with Dr. Andy Galpin: Nutrition to Support Brain Health & Offset Brain Injuries
    I'm honored to share Episode 10, the final episode of Season 1 of Perform with Dr. Andy Galpin. Dr. Andy Galpin is a tenured full professor at California State University, Fullerton, where he co-directs the Center for Sport Performance and leads the Biochemistry and Molecular Exercise Physiology Laboratory. Andy is both a friend and a colleague, and I'm delighted to have assisted in the creation of this podcast. I'm certain you'll both enjoy and learn from it. Season 1 featured 10 episodes, where Dr. Galpin covered everything from building strength, the importance of strength for long-term health, the science of breathing, the benefits of sleep extension, genetic testing for personalized training, and nutrition for injury recovery. While we have Episode 10 of Perform with Dr. Andy Galpin here, please be sure to follow Perform with Dr. Andy Galpin on your preferred platform to listen to all the episodes from Season 1 and to get notified when Season 2 is released. Show notes for this episode can be found at performpodcast.com. Timestamps 00:00:00 Introduction from Dr. Andrew Huberman 00:01:08 Brain Health & Injury   00:05:06 Sponsors: LMNT & Continuum   00:08:16 Nutrition & Supplements for Brain Injury   00:12:44 Brain Injury Categories, Traumatic Brain Injury (TBI), Concussion   00:17:09 Brain Injury Pathophysiology   00:22:16 Burst Capillaries, Initial TBI Response   00:30:03 Delayed TBI Response, Neuroinflammation   00:34:19 Sponsors: Momentous & Maui Nui   00:36:52 Creatine Monohydrate; Second Impact Syndrome   00:41:52 Strength of Evidence Scale, Creatine   00:47:15 Creatine Doses, Frequency, Adverse Issues; Food Sources   00:53:22 Sponsors: AG1 & David Protein   00:56:05 Fish Oil, DHA, EPA   01:00:38 EPA & DHA Dosage, Timing, Adverse Issues; Food Sources; Omega-3 Index   01:04:46 Vitamin B2 (Riboflavin), Vitamin B   01:08:57 Riboflavin Dosages, Timing; Food Sources   01:11:25 Choline   01:18:37 Choline Supplements & Food Sources, Alpha GPC, Dosage   01:21:30 Branched-Chain Amino Acids (BCAAs), Sleep   01:25:04 BCAAs Dosage, Whole Food Sources   01:28:02 Magnesium   01:31:20 Magnesium Dosage, Timing, Supplements, Adverse Issue; Food Sources   01:33:09 Blueberry Anthocyanins   01:35:28 Anthocyanins Dosage; Food Sources   01:37:17 Caffeine & Brain Injury Recovery   01:38:50 Perform Episodes, Perform Newsletter, Acknowledgements   01:41:19 Zero-Cost Support, YouTube, Spotify & Apple Subscribe & Reviews, Sponsors, YouTube Feedback, Social Media   01:42:56 Conclusion by Andrew Huberman   Disclaimer
    Huberman Lab
    enAugust 14, 2024

    Dr. Layne Norton: Tools for Nutrition & Fitness

    Dr. Layne Norton: Tools for Nutrition & Fitness
    In this episode, my guest is Dr. Layne Norton, Ph.D., one of the world’s top experts in nutrition and training for physical fitness. We discuss how to evaluate scientific evidence and the validity of different practices aimed at achieving fat loss, muscle strength and hypertrophy, microbiome health, vitality, and longevity. We explore many hotly debated topics, including fasting, seed oils, saturated fats, sugar, red meat, artificial/low-calorie sweeteners, and GLP-1 agonists (e.g., Ozempic). Additionally, we delve into the timing of protein and carbohydrate intake relative to fasting and exercise, fat loss and sleep, and the benefits of dietary protein and fiber on overall health. We also discuss how to accelerate hypertrophy and fat loss, improve strength, whether we need to train to “failure,” how to enhance exercise recovery, and how to manage pain. We cover training before versus after age 50, whether metabolism changes with age, and the connection between muscle health and longevity. We also address why certain behaviors and supplements might work for some people but not others. Listeners to this episode will benefit greatly from Layne’s science-based expertise on a wide range of topics, including health, nutrition, and fitness. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Mateina: https://drinkmateina.com/huberman Eight Sleep: https://www.eightsleep.com/huberman Maui Nui: https://mauinuivenison.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Dr. Layne Norton 00:01:49 Sponsors: Mateina, Eight Sleep, Maui Nui 00:06:39 Science-Based Evidence, Mechanism vs. Outcome 00:14:31 Meta-analysis, Methods, Evidence Quality 00:22:45 Evidence Hierarchy, Randomized Controlled Trials, Cohort Data 00:33:53 Sponsor: AG1 00:35:05 “Don’t Turn Your Brain Off”; Protein Synthesis 00:42:01 Protein Synthesis, Refractory Response; Resistance Training   00:46:05 Protein Intake, Intermittent Fasting & Training 00:54:52 Tool: Total Protein Intake, Distribution & Protein Synthesis 01:00:25 Muscle Quality, Protein Remodeling, Muscle Growth 01:05:34 Sponsor: LMNT 01:06:46 Early vs. Late Time-Restricted Eating; Fasting Blood Glucose & HbA1c 01:10:30 Carbohydrate Timing, Individual Response, Placebo; Tool: Tracking Diet 01:19:50 “The Norton Method”; Tool: Consistency 01:25:16 Resistance & Cardiovascular Training; Competition; Immune System & Rest 01:33:50 Mind & Body Effects, Stress; Belief Effects 01:41:30 Training to Failure, Reps in Reserve, Hypertrophy & Strength Training 01:50:24 Fatigue & Training to Failure, Speed, Strength Training 01:59:06 Tool: Training After 50, Consistency 02:09:12 Fat Cells, Diabetes, Exercise 02:16:50 Metabolism & Age-Related Changes?, Appetite 02:23:17 Ozempic, Mounjaro, GLP-1 Agonists, Lean Mass, “Food Noise” 02:33:42 GLP-1 Agonists, Judgement & Obesity 02:40:19 Sugar, Excess Calories, Body Weight 02:49:16 Satiety, Sugar & Calorie Budget 02:54:56 Tool: Individualization, Context & Diet Psychology 02:57:22 Seed Oils, Butter, Olive Oil 03:06:56 Red Meat, Carcinogenic?; Simple Diet; Fiber Benefits 03:13:43 Saturated Fat, Cholesterol; Seed Oils 03:18:41 Artificial & Low-Calorie Sweeteners, Insulin, Appetite 03:29:06 Artificial & Low-Calorie Sweeteners, Gut Microbiome; Cancer 03:37:58 Tools: Training Recovery, Glycogen Replenishment; Stress & Activity 03:45:56 Collagen Supplementation, Skin & Nails, Whey Protein 03:57:00 Evidence-Based Approach 04:01:41 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures
    Huberman Lab
    enAugust 12, 2024

    Dr. Martha Beck: Access Your Best Self With Mind-Body Practices, Belief Testing & Imagination

    Dr. Martha Beck: Access Your Best Self With Mind-Body Practices, Belief Testing & Imagination
    In this episode, my guest is Dr. Martha Beck, Ph.D., a Harvard-trained sociologist, bestselling author, and one of the world’s foremost experts on personal exploration and development.  Dr. Beck shares specific frameworks and practices to tap into your unique and deepest desires, core truths, and best life direction—all elements that comprise your authentic self. She also explains how to align your work and relationships of all kinds with your true self and how to embrace the discomfort and process of leaving unhealthy relationships. We discuss how to deal with negative thoughts and emotions, grapple with societal norms, and improve body awareness to gauge your inner truth. We also discuss codependency and self-abandonment - and how to exit and recover from these experiences.  By the end of the episode, you will have learned numerous practical tools to access your best self and live a richly fulfilling life.  Access the full show notes for this episode at hubermanlab.com. Dr. Beck's Wayfinder Life Coach Training: https://marthabeck.com/life-coach-training Thank you to our sponsors AG1: https://drinkag1.com/huberman BetterHelp: https://betterhelp.com/huberman Helix Sleep: https://helixsleep.com/huberman LMNT: https://drinklmnt.com/huberman Waking Up: https://wakingup.com/huberman Timestamps 00:00:00 Dr. Martha Beck 00:01:34 Sponsors: BetterHelp, Helix Sleep & LMNT 00:05:34 Tool: Perfect Day Exercise 00:15:31 “Clear Eyed”, Male vs. Female 00:23:31 Family & Work; Directed Attention & Miracles 00:30:21 Sponsor: AG1 00:32:10 Unease, Restlessness & Guilt; Life Worth, Fear 00:37:22 Accessing the Subconscious; Compassionate Witness Self 00:46:16 Finding Self, Suffering, Anxiety; Tool: “KIST”, Self-Parenting 00:54:01 Self, Radiance, Death; Awakening 00:59:14 Suffering & Compassionate Attention 01:02:10 Challenging Internal Thoughts, Understanding Truth, Body & Mind; 01:08:44 Sponsor: Waking Up 01:10:20 Western Society & Pressure 01:18:30 Tool: Sensing Truth in Body; Meditation, “Stopping the World” 01:25:02 Energy, Magnetoreception, Pet’s Death 01:33:49 Lying to Ourselves, Addiction 01:38:18 Tool: “Integrity Cleanse”, Lies; The Light 01:47:32 Relationship with Loss; Love, Self-Abandonment & Codependency 01:55:10 Romantic Relationships; Jobs & Family 02:02:06 Hurting Others, Relationship Imbalance 02:06:55 Tool: True Empathy 02:11:26 “Happiness is an Inside Job”, Codependency 02:18:58 Live Your Joy, Western Society 02:24:41 Relationships, Love & Integrity, “Feeling Good By Looking Weird” 02:30:42 “I Like It!”, Punk Rock Music, Love 02:34:24 Honesty & Essential Self; Helping People & Healers 02:42:12 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures
    Huberman Lab
    enAugust 05, 2024

    AMA #18: Cold Therapy Advice, Skin Health Tips, Motivation, Learning Strategies & More

    AMA #18: Cold Therapy Advice, Skin Health Tips, Motivation, Learning Strategies & More
    Welcome to a special edition of the 18th Ask Me Anything (AMA) episode, part of Huberman Lab Premium. This episode is a recording of the live stream AMA, exclusive to our Premium members. We've decided to make the full-length version available to everyone, including non-members of Huberman Lab Premium. Huberman Lab Premium was launched for two main reasons. First, it was launched in order to raise support for the main Huberman Lab podcast — which will continue to come out every Monday at zero-cost. Second, it was launched as a means to raise funds for important scientific research. A significant portion of proceeds from the Huberman Lab Premium subscription will fund human research (not animal models) selected by Dr. Huberman, with a dollar-for-dollar match from the Tiny Foundation and other donors. If you're not yet a member but enjoyed this full-length livestream AMA, we invite you to join Huberman Lab Premium. By subscribing, you'll gain access to exclusive benefits including our regular monthly full-length AMA episodes, AMA transcripts, podcast episode transcripts, early access to live events and more. Additionally, a significant portion of your membership proceeds contributes to advancing human scientific research. You can learn more about the research we were able to support in our Annual Letter 2023. If you're a Huberman Lab Premium member, you can access the transcript for this AMA episode here. Timestamps 00:00 Introduction & Announcements 00:15 Supporting Mental & Physical Health Research 01:56 Exciting New Research Initiatives 03:39 Skin Health & Appearance 14:46 Cold Therapy Benefits & Guidelines 21:18 Self-Motivation Strategies 27:05 Understanding REM Sleep 28:45 Morning Routine: Exercise & Cold Exposure 29:17 The Importance of REM Sleep 29:49 Non-Sleep Deep Rest (NSDR) Protocols 31:27 REM Sleep Rebound & Compensation 32:55 Impactful School Strategies for Learning 34:19 Meditation & Micro Gaps in Learning 39:13 Physical Activity & Learning 41:01 Exploring Shilajit & Testosterone 47:51 Writing Process & Overcoming Obstacles 51:32 Addiction & Recovery Resources 53:47 Closing Remarks & Gratitude Disclaimer & Disclosures
    Huberman Lab
    enAugust 02, 2024

    Dr. Peter Attia: Supplements for Longevity & Their Efficacy

    Dr. Peter Attia: Supplements for Longevity & Their Efficacy
    In this episode, my guest is Dr. Peter Attia, M.D., a Stanford and Johns Hopkins School of Medicine-trained physician expert in improving human healthspan and lifespan. Dr. Attia is also the host of The Drive podcast and author of the best-selling book Outlive.  We discuss the NAD pathway in human cells and its possible links to aging and health. We evaluate how supplementation can augment molecules in the NAD pathway; we compare NAD, NMN, and NR, different routes of administration, their safety, and bioavailability. Then, we discuss the broader research and clinical literature on longevity to decide if supplementation with NAD, NR, NMN, rapamycin, or resveratrol can indeed extend lifespan.  Finally, we each describe our supplement regimens and compare the role of supplementation to behaviors such as sleep, nutrition, and exercise for longevity. We also discuss whether tests of biological age are true indicators of aging and whether normal radiation levels increase cancer risk.  Listeners of this episode will learn if supplements purported to improve lifespan show any efficacy and the behaviors and other factors that can prevent disease and extend lifespan. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman LMNT: https://drinklmnt.com/huberman Levels: https://levels.link/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps 00:00:00 Dr. Peter Attia, NAD Pathway 00:02:31 Sponsors: LMNT, Levels & Eight Sleep 00:06:38 Categories of Longevity Approaches 00:17:22 Peter’s Supplements; Rapamycin & Research Data 00:25:01 NAD Pathway: Energy & DNA Repair; Knock-Out & Knock-In, Klotho 00:30:35 Sponsor: AG1 00:32:25 Yeast, Sirtuins, Caloric Restriction & Lifespan 00:38:56 Sirtuins, Transgenic Mice, Gender & Lifespan 00:43:42 DNA Repair, Sirtuins, Cancer; Resveratrol 00:53:31 Perform with Dr. Andy Galpin Podcast 00:54:18 NAD & NADH, Reactive Oxygen Species (ROS), Mitochondrial Health 01:02:17 NAD vs NR vs NMN Supplementation; IV & Oral Routes 01:11:33 NR vs. NMN, Doses, Side Effects; Interventions Testing Program 01:17:43 Fatty Liver Disease & NR; NMN & Glucose; Clinical Significance 01:25:17 Safety & FDA, NMN & NR Supplementation; Skin Cancer Benefits 01:30:38 Longevity, NR & NMN Supplementation, Inflammation 01:41:00 Rapamycin & Immune Function 01:44:37 Biological Aging Tests, Chronologic & Biologic Age; Vigor  01:55:24 Radiation & Cancer Risk 01:58:12 Tool: Self-Care in 50s-70s & Aging; Energy Decline 02:07:12 Tool: Exercise Timing & Energy Levels 02:11:22 Peter’s Supplements 02:18:46 Andrew’s Supplements 02:24:34 Tool: Supplement Use vs. Critical Behaviors; Titanic Analogy  02:26:52 NAD Pathway Supplementation for Longevity? 02:28:52 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, YouTube Feedback, Social Media, Neural Network Newsletter Disclaimer
    Huberman Lab
    enJuly 29, 2024

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