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    What Happens When An Infant Loses Half Their Brain?

    en-usMay 29, 2023

    Podcast Summary

    • A girl's story of resilience and humor despite a stroke before birthThe BBC's commitment to diverse storytelling fosters understanding and empathy, reminding us of the importance of resilience and the power of humor to bring joy and connection.

      The BBC provides valuable information and inspiration through storytelling, allowing us to broaden our perspectives without being told what to think. This was highlighted in the discussion about Mora Leeb, a 15-year-old girl who experienced a massive stroke before birth and faced numerous challenges growing up. Despite her unusual brain development, Mora's sense of humor and love for activities like tennis and soccer show that she's just like any other teenager. Her story serves as a reminder of the importance of resilience and the power of a good joke to bring joy and connection. The BBC, with its commitment to sharing diverse stories, plays a crucial role in fostering understanding and empathy in a complex world. Support for this podcast comes from Equinix, the world's digital infrastructure company, empowering businesses to achieve their goals through advanced technology and partnerships.

    • Loss of Half a Brain in Infancy: Severe Consequences and Surprising RecoveryDespite the severe consequences of losing half a brain in infancy, including the inability to roll over, smile, or speak, extensive therapy can lead to surprising recoveries, challenging previous assumptions about brain plasticity.

      The loss of half a brain in an infant, as in the case of Maura, can lead to severe consequences including the inability to roll over, smile, or speak. The damaged or dead cells in the brain cause seizures, and surgeons may offer the only solution of removing the affected side, resulting in a significant loss of functions. The left side of the brain, where speech and language usually reside, is particularly important in this context, leaving the question of whether the child will regain these abilities open. Despite the initial challenges, Maura's story is one of success, with extensive physical and cognitive therapy playing a crucial role in her recovery. The findings from her case have surprised researchers, challenging previous assumptions about the brain's plasticity and adaptability.

    • Impact of brain injury on early childhood developmentBrain injury during early childhood can lead to developmental delays and impact functions like language and face recognition, but the exact impact is not well understood.

      During early childhood development, the brain is still in the process of wiring and organizing functions such as language and face recognition. Losing half of this wiring, as in the case of Mora, can lead to developmental delays. For instance, she sat up late, walked late, and began using sentences much later than typical children. The exact impact of losing half a brain on the development of these functions is not well understood, as there are limited studies on such cases. Researchers like Michael Granovetter suggest that functions like word recognition and face recognition initially compete for space in the brain, eventually settling on opposite sides. If only one hemisphere is available, it's unclear how these functions would adapt. Doctors face challenges in providing reassurances to parents when they don't have definitive answers about the developmental trajectory of children with such injuries.

    • Children with brain injuries recover better than adults in face and word recognitionChildren who lose half of their brains as children can still achieve impressive levels of recovery in face and word recognition, with abilities significantly less impaired than adults with similar injuries

      Despite losing half of their brains as children, some individuals are able to achieve impressive levels of recovery in face and word recognition. This was a surprising finding, as research suggests that adults with stroke injuries in the left hemisphere, which is responsible for language and reading skills, experience profound impairments. However, a study conducted by Michael and his team on 40 individuals who had undergone such injuries as children revealed that these individuals were able to recognize both faces and words with 80% accuracy, even when the left hemisphere was preserved. This finding was confirmed by Marlene Berman, an expert on visual cognition at Carnegie Mellon University. Although there are some limitations to their abilities, these children's impairments are significantly less severe than those seen in adults with similar injuries. Dr. Lisa Schulman, a neurodevelopmental pediatrician, further explained that these children's brains have adapted to take on the tasks that the damaged hemisphere would normally handle. While they may not reach the same level of accuracy as individuals with typical brains, their recovery is a testament to the brain's remarkable ability to adapt and compensate for injury.

    • Brain injuries impact language and motor skills differentlyBrain injuries can result in unique language and motor challenges, but with determination and support, progress can be made.

      Brain injuries, particularly those affecting the left side, can significantly impact language abilities and motor functioning. Mora, a girl with such an injury, exhibits a high level of understanding for sophisticated linguistic concepts like idioms, but struggles with processing unfamiliar concepts or jokes with sneaky punch lines. For instance, she found a science-nerd joke about a termite in a bar difficult to comprehend. This challenge is not limited to jokes, as her right side will never be as strong as her left, making certain tasks more difficult. Despite these challenges, Mora continues to make remarkable progress, surprising her doctors with her advanced understanding of certain concepts. It's a reminder that brain injuries can lead to unique and complex challenges, but with determination and support, progress can be made.

    • The Amazing Ability of the Human Brain to Adapt and OvercomeDespite severe injuries, the human brain has the ability to adapt and rewire itself, as shown by Maura Morin's progress in social skills and personality development, offering hope for brain injury patients and challenging previous beliefs about brain plasticity.

      The human brain has an incredible ability to adapt and rewire itself, even in the face of severe injuries. Maura Morin, who has a visual deficit and only sees a half view of the world, is an extreme example of this plasticity. Despite her condition, she is making progress in other areas, such as social skills and personality development. This discovery gives neuroscientists and doctors hope for the recovery of brain injury patients, offering a renewed sense of possibility and optimism. Maura's mother, Ann Lee, is confident that her daughter will continue to exceed expectations and reach new levels in the coming years. The study of Maura's case, along with others, is helping to challenge previous beliefs about the limits of brain plasticity. This episode of Shortwave from NPR was produced by Britt Hanson, edited by Rebecca Ramirez, fact-checked by John Hamilton, and engineered by Stacy Abbot. Special thanks to Amina Khan. For more updates on Maura's progress, stay tuned to Shortwave from NPR. Support for this podcast comes from Easycater and Capella University.

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