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    Aging and Senior Health (Audio)

    University of California researchers and clinicians keep you in the know about the latest in aging and senior health research.
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    Episodes (50)

    Resilience and Aging

    Resilience and Aging
    Lisa Eyler, Ph.D., Colin Depp, Ph.D., Joe Garbanzos, M.B.A., and Irving Tragen, J.D., address various aspects of resilience, ageism, and healthy aging. They emphasize the need to challenge ageist stereotypes and create inclusive communities that support people of all ages. The importance of storytelling, community initiatives, and a commitment to creating possibilities for those aged 50+ is highlighted. Tragen, a centenarian, shares his unique perspective on aging with anecdotes and advice that everyone can apply to their daily lives. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 39130]

    Interventions for Healthy Longevity

    Interventions for Healthy Longevity
    Explore ways to keep your brain and body in good shape as you get older.Alison Moore, M.D., M.P.H., F.A.C.P., Steve Cummings, M.D., Steve Hornberger, M.S.W., and Judy Pa, Ph.D. discuss the impacts of exercise, eating well, staying socially active, taking vitamins, and even trying new activities like learning a new language or playing music. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 39129]

    Telomeres in Cancer and Aging with Ronald DePinho - Sanford Stem Cell Symposium 2023

    Telomeres in Cancer and Aging with Ronald DePinho - Sanford Stem Cell Symposium 2023
    Ronald DePinho, M.D., explains how telomerase, typically linked to telomere maintenance, serves as a transcriptional co-activator in the brain. Epigenetic repression of TERT, the gene for telomerase, occurs with aging, contributing to aging hallmarks like cellular senescence and inflammation. DePinho's team developed a compound that reactivates TERT, which, when administered to mice, reverses age-related changes. It restores cognitive function, reduces amyloid plaque, and alleviates inflammation. This suggests that maintaining TERT levels can counteract age-related cognitive decline and neurodegeneration, offering potential for treating neurodegenerative diseases like Alzheimer's. DePinho's work expands our understanding of telomerase's multifaceted role in aging and neurodegeneration, holding promise for interventions against these age-related processes. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39071]

    Clonal Expansion of Blood Stem Cells in Aging and Leukemia with Leonard Zon - Sanford Stem Cell Symposium 2023

    Clonal Expansion of Blood Stem Cells in Aging and Leukemia with Leonard Zon - Sanford Stem Cell Symposium 2023
    Leonard Zon, M.D., discusses cutting-edge research on the intricate relationship between macrophages, stem cells, and the development of leukemia using the zebrafish model. He delves into the fascinating interactions between these cell types, highlighting the role of a "don't eat me" signal and the influence of the leukemic niche. Through cellular barcoding and single-cell RNA sequencing, he unveils a potential therapeutic target which may offer promising insights into treating leukemia by disrupting the stromal activities that support it. Zon showcases the power of zebrafish models in advancing our understanding of hematopoiesis and cancer, promising new avenues for research and treatment. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39064]

    Drivers of Healthy Longevity

    Drivers of Healthy Longevity
    What drives longevity? Explore the keys to healthy aging in this panel discussion featuring leading experts in public health, nutrition, and medicine. You'll get a comprehensive analysis of how lifestyle choices, diet, and exercise profoundly impact our healthspan and longevity. The panelists discuss the significance of the Mediterranean diet, the role of physical activity in maintaining wellness, and the potential benefits of medications like Metformin for non-diabetic patients. This engaging session also highlights the crucial influence of our environment and social structures on individual health behaviors. Discover actionable insights and the latest scientific findings on aging gracefully and improving your quality of life. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 39127]

    Healthy Aging: Social and Societal Implications

    Healthy Aging: Social and Societal Implications
    S. Jay Olshansky, Ph.D., shares how science is unlocking the secrets of aging. Learn how we can live healthier and longer lives by understanding the biology of aging. Find out about potential breakthroughs and the impact of genetics on diseases like cancer and Alzheimer's. Explore the "longevity dividend" and the quest to compress the "red zone" of aging. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 39126]

    The Miraculous Healing Power of Food with Anthony Lim - Lee Tuh-Fuh And Ruby Lee Wang Zu-Ming Endowed Lecture

    The Miraculous Healing Power of Food with Anthony Lim - Lee Tuh-Fuh And Ruby Lee Wang Zu-Ming Endowed Lecture
    Anthony Lim, M.D., J.D. shares the keys to vibrant health. Dr. Lim shares methods to prevent kidney stones, tackle fatty liver disease through a whole-food, plant-based diet, and more. Learn how food choices can transform your well-being and get practical solutions. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 39020]

    What Do We Know About How to Foster Mental Wellbeing as We Age?

    What Do We Know About How to Foster Mental Wellbeing as We Age?
    Explore aging's impact on well-being with Barton Palmer, Ph.D. Learn how resilience, optimism, and social connections shape happiness in later life. Discover practical interventions like mindfulness and value-driven actions. Understand the role of positive psychology and spirituality. Delve into adapting interventions for cognitive changes. Gain valuable insights into navigating challenges and fostering well-being as we age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 38972]

    Physical Activity and Brain Health in Aging

    Physical Activity and Brain Health in Aging
    Engaging in everyday physical activity can influence brain and cognitive health. Zvinka Z. Zlatar, Ph.D., shares how physical activity can potentially reduce risk for Alzheimer's disease and other cognitive issues. She reviews the current excercise recommendations for older adults and how digital devices can help us reach our goals. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 38693]

    What Can Geroscience Teach Us About Healthy Longevity?

    What Can Geroscience Teach Us About Healthy Longevity?
    Aging research has come a long way in the past few decades, and scientists are now starting to understand the biology of aging. Anthony J.A. Molina, Ph.D., shares the latest findings in the field of geroscience, or the study of how to delay the onset of age-related diseases and extend healthy lifespan. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 38634]

    Looking to a Future Without Alzheimer's

    Looking to a Future Without Alzheimer's
    Alzheimer’s disease is a major health crisis that is projected to become an even larger threat in the coming decades. According to the National Institute on Aging, the number of Americans 65 and older with Alzheimer’s could rise from 5.8 million in 2020 to 13.8 million by 2050. Given the severity of this health crisis and the toll it takes on patients, their families and society, we must be prepared today to address the needs of tomorrow. Dean Frank LaFerla of UC Irvine's School of Biological Sciences presents an overview of the state of Alzheimer’s disease research. Following his presentation, the panel discusses emerging trends in research, care and the upcoming challenges we will face and how we might mitigate them. [Health and Medicine] [Show ID: 38660]

    Global Healthy Aging - A Review of Efforts to Support Healthy Aging From Around the World

    Global Healthy Aging - A Review of Efforts to Support Healthy Aging From Around the World
    The world's population is aging. How can we improve the lives of older people, their families, and their communities? Alison A. Moore, M.D., UC San Diego, shares the impacts of studying healthy aging globally. From the World Health Organization (WHO) to the UN and locally in San Diego, learn how the world community is studying aging to improve health, equity, longevity and more. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 38425]

    How Stem Cells Contribute to Aging and Age-Related Diseases with Rob Signer

    How Stem Cells Contribute to Aging and Age-Related Diseases with Rob Signer
    What challenges does aging pose to both individuals and society at large? What causes aging at the cellular and molecular level? Stem cell research is be key to finding solutions that increase our healthspan and change how we think about aging. Robert A.J. Signer, Ph.D., shares what is on the horizon. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38215]

    A Closer Look at….Aging

    A Closer Look at….Aging
    What challenges does aging pose to individuals and society at large? What causes aging at the cellular and molecular level? What if we could trick stem cells into thinking they were young again? If so, could we leverage stem cells to help live longer, healthier lives? These are just some of the fascinating questions researchers are exploring in today's closer look at the aging process. Robert A.J. Signer, Ph.D., and Shiri Gur-Cohen, Ph.D., examine aging at the molecular and cellular level to show how stem cells may be the key to preventing age-related health problems. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37968]