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Creative Biolabs offers clients a novel bispecific antibody (BsAb) format, the dual variable domain IgG (DVD-IgG), for many diverse studies in antibody engineering. We aim to provide the reliable, efficient services to meet our customer’s individual requirements.
https://www.creativebiolabs.net/Dual-variable-domain-IgG-DVD-IgG.htm

Creative Biolabs offers clients a novel bispecific antibody (BsAb) format, the dual variable domain IgG (DVD-IgG), for many diverse studies in antibody engineering. We aim to provide the reliable, efficient services to meet our customer’s individual requirements.
https://www.creativebiolabs.net/dual-variable-domain-igg-dvd-igg.htm

DVD-IgG is one type of bispecific antibody format, which is generated from two parental mAbs by placing two variable domains from one parental antibody onto the heavy chain and the light chain of another parental antibody, instead of one variable domain. The variable domain pairs can be derived from whole human, mouse or rat mAbs with phage/yeast display libraries. And the short peptides derived from the N-termini of CH1 or CL link the outer variable domain (VD1) and the inner variable domain (VD2) together. The DVD-IgG retains the antigen-binding specificity, affinity, and biologic activities from its both parental antibodies, therefore, all of its four variable domains are functional. Many different DVD-IgGs have been designed and manufactured for treating complex diseases with multiple mediators contributing to overall disease pathogenesis.
https://www.creativebiolabs.net/dual-variable-domain-igg-dvd-igg.htm

Creative Biolabs is professional in producing Fab fragment antibodies using well established methods. We provide the most comprehensive list of Fab fragment antibodies.
https://www.creativebiolabs.net/Fab-Fragment-Antibodies_24.htm

Because of its high binding capability and easy production character, tandem scFv-Fc bispecific antibody (BsAb) is one of the leading candidates for antibody drug development. Creative Biolabs elaborately integrates its multiple platforms to provide customers a desired tandem scFv-Fc BsAb with high affinity and low immunogenicity for both academic and clinical purposes.

https://www.creativebiolabs.net/tandem-scfv-fc-bispecific-antibody-bsab.htm

At Creative Biolabs, the proprietary protocol and tailored biopanning strategy allow the increase of candidates with higher affinity and desired specificity (e.g. binders recognize conformational epitope rather than linear epitope). In general, by conducting four rounds library screening, our scientists can select scFv/Fab antibodies with the affinity of 10-7. Through constructing serial sub-libraries of the isolated scFv/Fab antibodies, we can increase the affinity from 10-8 to 10-9. Moreover, Creative Biolabs has successfully obtained a scFv antibody with an extremely high affinity of 10-12.
https://www.creative-biolabs.com/phage-display-library-screening.html

Phage display technology is one of the major approaches employed in various protein interaction studies, especially in the discovery of specific antibodies, scaffolds or ligands. While binders with the desired specificity generally exist at low frequencies in the constructed libraries. In this way, phage display library screening has become an effective technique for the enrichment and identification of binders with high affinity and specificity from interested libraries.
https://www.creative-biolabs.com/phage-display-library-screening.html

Phage display technology is one of the major approaches employed in various protein interaction studies, especially in the discovery of specific antibodies, scaffolds or ligands. While binders with the desired specificity generally exist at low frequencies in the constructed libraries. In this way, phage display library screening has become an effective technique for the enrichment and identification of binders with high affinity and specificity from interested libraries.
https://www.creative-biolabs.com/phage-display-library-screening.html

Phage display technology is one of the major approaches employed in various protein interaction studies, especially in the discovery of specific antibodies, scaffolds or ligands. While binders with the desired specificity generally exist at low frequencies in the constructed libraries. In this way, phage display library screening has become an effective technique for the enrichment and identification of binders with high affinity and specificity from interested libraries.
https://www.creative-biolabs.com/phage-display-library-screening.html

At Creative Biolabs, the proprietary protocol and tailored biopanning strategy allow the increase of candidates with higher affinity and desired specificity (e.g. binders recognize conformational epitope rather than linear epitope). In general, by conducting four rounds library screening, our scientists can select scFv/Fab antibodies with the affinity of 10-7. Through constructing serial sub-libraries of the isolated scFv/Fab antibodies, we can increase the affinity from 10-8 to 10-9. Moreover, Creative Biolabs has successfully obtained a scFv antibody with an extremely high affinity of 10-12.
https://www.creative-biolabs.com/phage-display-library-screening.html

As a well-recognized expert at phage display technology, Creative Biolabs offers our worldwide clients the best phage display library screening services through our excellent biopanning strategies and state-of-the-art equipment. Our scientists are pleased to tailor the most appropriate strategies to screen the interested libraries of our customers.
https://www.creative-biolabs.com/phage-display-library-screening.html

Phage display is a kind of long-lasting laboratory platform for the large-scale study of molecules interaction, such as protein-protein, protein-peptide and protein-DNA interactions, and select molecules with the highest affinity for specific targets. The technology was firstly described by Smith (1985), and then be further expanded by such groups of pioneers, e.g. Greg Winter and John McCafferty (Laboratory of Molecular Biology), Richard Lerner and Carlos Barbas (Scripps Research Institute), and Frank Breitling and Stefan Dübel (German Cancer Research Center).
https://www.creative-biolabs.com/phage-display-platform.html

Phage display is a kind of long-lasting laboratory platform for the large-scale study of molecules interaction, such as protein-protein, protein-peptide and protein-DNA interactions, and select molecules with the highest affinity for specific targets. The technology was firstly described by Smith (1985), and then be further expanded by such groups of pioneers, e.g. Greg Winter and John McCafferty (Laboratory of Molecular Biology), Richard Lerner and Carlos Barbas (Scripps Research Institute), and Frank Breitling and Stefan Dübel (German Cancer Research Center).
https://www.creative-biolabs.com/phage-display-platform.html

Phage display is a kind of long-lasting laboratory platform for the large-scale study of molecules interaction, such as protein-protein, protein-peptide and protein-DNA interactions, and select molecules with the highest affinity for specific targets. The technology was firstly described by Smith (1985), and then be further expanded by such groups of pioneers, e.g. Greg Winter and John McCafferty (Laboratory of Molecular Biology), Richard Lerner and Carlos Barbas (Scripps Research Institute), and Frank Breitling and Stefan Dübel (German Cancer Research Center).
https://www.creative-biolabs.com/phage-display-platform.html

The incredible Magic™ High-throughput Antibody Production Service of Creative Biolabs has adopted all the mature technologies relating to the high-throughput antibody production. Meanwhile, our diligent scientists are still vigilant to any emerging novel concepts and strategies for perfecting our superior antibody screen and expression service harboring the most excellent high-throughput capacity. Currently, the gorgeous service at Creative Biolabs is able to perform the best high-throughput antibody expression with sufficient amounts among various eukaryotic and prokaryotic hosts. Noticeable, the numerous antibodies produced and purified at our service have successfully applied in almost every area of basic research and a considerable number of demanding drug screens and developments.
https://www.creativebiolabs.net/magic-high-throughput-antibody-production-service.htm

We have developed proprietary procedures for Hi-Affi™ recombinant antibody production, with optimized library construction and screening processes using hybridoma or phage display technology. We guarantee successful isolation of clones in a short time with high affinity up to sub-nanomolar level. Bulk order from 1mg to 10g is also available.
https://www.creativebiolabs.net/Hi-Affi-TM-Recombinant-Antibodies.htm

Creative Biolabs is professional in producing Fab fragment antibodies using well established methods. We provide the most comprehensive list of Fab fragment antibodies.
https://www.creativebiolabs.net/Fab-Fragment-Antibodies_24.htm

Epitope, aslo known as antigenic determinant, is the part of an antigen that is recognized by the immune system, specifically by antibody. For each antibody-related scientific research, specific epitope is always required for selection of antibody with validated binding affinity and biological function. Creative biolabs is world-renowned biotechnology company specialized in antibody development. We have already launched a series of antibody product, for which the corresponding epitope is determined.
https://www.creativebiolabs.net/epitope-specific-antibody_69.htm

Creative Biolabs is a pioneer in antibody development and production in full range of applications. We committed to provide full range of anti-ID antibody products of high-quality for using in different area. Beyond an increasing number of our anti-ID antibody products, comprehensive anti-ID antibody custom service is also available for our clients to choose for their researches.
https://www.creativebiolabs.net/anti-idiotypic-antibody_71.htm