Dermatology

Guest: Terry Faleye, MPAS, PA-C
Guest: Jonathan I. Silverberg, MD, PhD, MPH

Atopic dermatitis (AD) significantly impacts physical, social, and psychological well-being. Recently, novel and more effective treatment options have been approved, including those targeting interleukin (IL)-13. Tune in to watch this webcast on incorporating these agents to optimize care for patients with moderate to severe AD with Terry Faleye, Dermatology Physician Assistant at DermSurgery Associates in Houston, Texas, and Dr. Jonathan Silverberg, Professor, Director of Clinical Research, and Director of Patch Testing at George Washington University School of Medicine and Health Sciences in Washington, DC.

Guest: Cara Dolin, MD
Guest: Jennifer Simpson
Guest: Diana Girnita, MD ,PhD

Explore this video roundtable featuring an interdisciplinary panel of experts discussing a woman’s journey with mycophenolate therapy and strategies to approach risk mitigation. Learn more about how to provide critical education on the risks of mycophenolate, the importance of effective contraception, and navigating family planning.

Host: Jeffrey S. Weber, MD, PhD
Host: Ryan Sullivan, MD
Host: Omid Hamid, MD

Approximately 50 - 60% of patients with melanoma have BRAF-activating tumors, meaning they are amenable to treatment with combination BRAF/MEK inhibitors. However, immunotherapy is also a highly effective treatment for patients with BRAF-activating tumors. Given the benefit of both types of therapies in the adjuvant setting, there are uncertainties regarding which adjuvant treatment to offer patients with stage III disease. The critical question revolves around which adjuvant treatment strategy provides the best opportunity for sustained recurrence-free survival.

Report with a jury of your peers to debate the optimal adjuvant treatment approach for a patient with fully resected, stage III BRAF-mutant melanoma. View the persuasive evidence and listen to expert witnesses defend the pros and cons for this high-risk patient population. Cast your polling vote as the case proceeds. We’ll see you in court to render a verdict in an important case with implications for your clinical practice!

Host: Omid Hamid, MD
Host: Sapna Patel, MD
Host: Ryan Sullivan, MD
Host: Jeffrey S. Weber, MD, PhD

Approximately 50 - 60% of patients with melanoma have BRAF-activating tumors, meaning they are amenable to treatment with combination BRAF/MEK inhibitors. However, immunotherapy is also a highly effective treatment for patients with BRAF-activating tumors. Given the benefit of both types of therapies in the adjuvant setting, there are uncertainties regarding which adjuvant treatment to offer patients with stage III disease. The critical question revolves around which adjuvant treatment strategy provides the best opportunity for sustained recurrence-free survival.

Report with a jury of your peers to debate the optimal adjuvant treatment approach for a patient with fully resected, stage III BRAF-mutant melanoma. View the persuasive evidence and listen to expert witnesses defend the pros and cons for this high-risk patient population. Cast your polling vote as the case proceeds. We’ll see you in court to render a verdict in an important case with implications for your clinical practice!

Host: Jeffrey S. Weber, MD, PhD
Host: Jason J. Luke, MD, FACP
Host: Ryan Sullivan, MD
Host: Omid Hamid, MD

Approximately 50 - 60% of patients with melanoma have BRAF-activating tumors, meaning they are amenable to treatment with combination BRAF/MEK inhibitors. However, immunotherapy is also a highly effective treatment for patients with BRAF-activating tumors. Given the benefit of both types of therapies in the adjuvant setting, there are uncertainties regarding which adjuvant treatment to offer patients with stage III disease. The critical question revolves around which adjuvant treatment strategy provides the best opportunity for sustained recurrence-free survival.

Report with a jury of your peers to debate the optimal adjuvant treatment approach for a patient with fully resected, stage III BRAF-mutant melanoma. View the persuasive evidence and listen to expert witnesses defend the pros and cons for this high-risk patient population. Cast your polling vote as the case proceeds. We’ll see you in court to render a verdict in an important case with implications for your clinical practice!

Host: Jeffrey S. Weber, MD, PhD
Host: Ryan Sullivan, MD
Host: Omid Hamid, MD

Approximately 50 - 60% of patients with melanoma have BRAF-activating tumors, meaning they are amenable to treatment with combination BRAF/MEK inhibitors. However, immunotherapy is also a highly effective treatment for patients with BRAF-activating tumors. Given the benefit of both types of therapies in the adjuvant setting, there are uncertainties regarding which adjuvant treatment to offer patients with stage III disease. The critical question revolves around which adjuvant treatment strategy provides the best opportunity for sustained recurrence-free survival.

Report with a jury of your peers to debate the optimal adjuvant treatment approach for a patient with fully resected, stage III BRAF-mutant melanoma. View the persuasive evidence and listen to expert witnesses defend the pros and cons for this high-risk patient population. Cast your polling vote as the case proceeds. We’ll see you in court to render a verdict in an important case with implications for your clinical practice!

Host: Jeffrey S. Weber, MD, PhD
Host: Sapna Patel, MD
Host: Jason J. Luke, MD, FACP

Despite improved prognosis for melanoma patients due to advances in treatment options in recent years, survival rates for patients with metastatic disease remain low. With two mechanistically different immune checkpoint inhibitor combinations available, it is critical that clinicians be able to differentiate among currently approved regimens to inform frontline treatment selection in different patient populations. The crucial question revolves around which target, anti-CTLA-4 versus anti-LAG3, provides the greatest benefit in metastatic melanoma when combined with a PD-1 inhibitor.

Report with a jury of your peers to debate the optimal frontline treatment approach for a patient with unresectable stage IV BRAF-wild type melanoma. View the persuasive evidence and listen to expert witnesses defend the pros and cons for this vulnerable patient population. Cast your polling vote as the case proceeds. We’ll see you in court to render a verdict in an important case with implications for your clinical practice!

Host: Jeffrey S. Weber, MD, PhD
Host: Sapna Patel, MD
Host: Omid Hamid, MD
Host: Jason J. Luke, MD, FACP

Despite improved prognosis for melanoma patients due to advances in treatment options in recent years, survival rates for patients with metastatic disease remain low. With two mechanistically different immune checkpoint inhibitor combinations available, it is critical that clinicians be able to differentiate among currently approved regimens to inform frontline treatment selection in different patient populations. The crucial question revolves around which target, anti-CTLA-4 versus anti-LAG3, provides the greatest benefit in metastatic melanoma when combined with a PD-1 inhibitor.

Report with a jury of your peers to debate the optimal frontline treatment approach for a patient with unresectable stage IV BRAF-wild type melanoma. View the persuasive evidence and listen to expert witnesses defend the pros and cons for this vulnerable patient population. Cast your polling vote as the case proceeds. We’ll see you in court to render a verdict in an important case with implications for your clinical practice!

Host: Jeffrey S. Weber, MD, PhD
Host: Jason J. Luke, MD, FACP
Host: Ryan Sullivan, MD
Host: Sapna Patel, MD

Despite improved prognosis for melanoma patients due to advances in treatment options in recent years, survival rates for patients with metastatic disease remain low. With two mechanistically different immune checkpoint inhibitor combinations available, it is critical that clinicians be able to differentiate among currently approved regimens to inform frontline treatment selection in different patient populations. The crucial question revolves around which target, anti-CTLA-4 versus anti-LAG3, provides the greatest benefit in metastatic melanoma when combined with a PD-1 inhibitor.

Report with a jury of your peers to debate the optimal frontline treatment approach for a patient with unresectable stage IV BRAF-wild type melanoma. View the persuasive evidence and listen to expert witnesses defend the pros and cons for this vulnerable patient population. Cast your polling vote as the case proceeds. We’ll see you in court to render a verdict in an important case with implications for your clinical practice!

Host: Jeffrey S. Weber, MD, PhD
Host: Sapna Patel, MD
Host: Jason J. Luke, MD, FACP

Despite improved prognosis for melanoma patients due to advances in treatment options in recent years, survival rates for patients with metastatic disease remain low. With two mechanistically different immune checkpoint inhibitor combinations available, it is critical that clinicians be able to differentiate among currently approved regimens to inform frontline treatment selection in different patient populations. The crucial question revolves around which target, anti-CTLA-4 versus anti-LAG3, provides the greatest benefit in metastatic melanoma when combined with a PD-1 inhibitor.

Report with a jury of your peers to debate the optimal frontline treatment approach for a patient with unresectable stage IV BRAF-wild type melanoma. View the persuasive evidence and listen to expert witnesses defend the pros and cons for this vulnerable patient population. Cast your polling vote as the case proceeds. We’ll see you in court to render a verdict in an important case with implications for your clinical practice!

Host: Jason J. Luke, MD, FACP
Guest: Tara C. Mitchell, MD

The 5-year recurrence rates for stage IIB and IIC melanoma are up to 46%, but now new immunotherapy options are FDA-approved for the adjuvant treatment of stage IIB and IIC melanoma. Find out why this matters and hear Drs. Jason Luke and Tara Mitchell break down the latest data on treating stage IIB and IIC melanoma with adjuvant immunotherapy.

Guest: Peter A. Lio, MD
Guest: Mark Boguniewicz, MD
Guest: Eric Simpson, MD, MCR

Please note: This activity is no longer available for continuing education credit.

Tune in as a multidisciplinary panel discusses a clinician's question about the appropriateness of combining two biologics in a very young child with several atopic diseases.

Guest: Peter A. Lio, MD
Guest: Mark Boguniewicz, MD
Guest: Eric Simpson, MD, MCR

Please note: This activity is no longer available for continuing education credit.

A multidisiplinary panel is presented with a highly allergic, extremely refractory patient with atopic dermatitis. Her dermatologist wants to take the next step and start her on a biologic, but she's worried about the patient's occular history and dupilumab's conjunctivitis risk. Find out what the experts have to say about this doctor's dilemma.

Guest: Peter A. Lio, MD
Guest: Mark Boguniewicz, MD
Guest: Eric Simpson, MD, MCR

Please note: This activity is no longer available for continuing education credit.

Infants have the highest incidence of atopic dermatitis in the US but the fewest treatment options. This is a case a doctor submitted about a baby who is refractory to multiple oral and topical treatments. A multidisciplinary panel discusses how they would approach the baby's treatment, emerging options for this vulnerable patient population, and if anything can be done now to prevent progression of the atopic march later.

Host: Peter A. Lio, MD
Guest: Eric Simpson, MD, MCR
Guest: Mark Boguniewicz, MD

Please note: This activity is no longer available for continuing education credit.

“I begged my doctor for something else – there had to be something else,” Pam.

For over 50 years, Pam suffered with uncontrolled moderate-to-severe atopic dermatitis (AD). She experienced the evolution of treatment strategies over the course of the several decades, trying everything from topicals to off-label targeted systemic agents. She was willing to try anything to make the unbearable itch go away. In this roundtable discussion, we brought Pam and her dermatologist to discuss AD with a multidisciplinary physician panel. Together they weigh in on experimental and newly approved therapies, management strategies, impact on quality-of-life, and shared decision-making techniques, all supplemented by Pam’s unfiltered, down-to-earth reality check of what life with AD and all these drugs really feels like.