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    colocalization

    Explore "colocalization" with insightful episodes like "Tackling Racial Disparities in HCV Care" and "N-acetyllactosamine (lacNAC) reverts human TIL anergy ex vivo." from podcasts like ""CCO Infectious Disease Podcast" and "Tumor Immunology Round Table"" and more!

    Episodes (2)

    Tackling Racial Disparities in HCV Care

    Tackling Racial Disparities in HCV Care

    In this episode, Oluwaseun Falade-Nwulia, MBBS, MPH, and Joseph K. Lim, MD, examine the HCV burden and care disparities in specific populations, including Black, Hispanic, Asian, American Indian, and Alaska Native persons, and strategies to address barriers to care.

    Oluwaseun Falade-Nwulia, MBBS, MPH
    Associate Professor
    Division of Infectious Diseases
    Johns Hopkins University School of Medicine
    Attending
    Division of Infectious Diseases
    Johns Hopkins Hospital
    Baltimore, Maryland

    Joseph K. Lim, MD
    Professor of Medicine
    Director, Clinical Hepatology
    Vice-Chief
    Section of Digestive Diseases
    Yale University School of Medicine
    New Haven, Connecticut

    Content based on a CME program supported by educational grants provided by AbbVie, Gilead Sciences, Inc., and Janssen Therapeutics, Division of Janssen Products, LP 

    To follow along, download the slides at:
    https://bit.ly/36UDLVi

    Link to full program:
    https://bit.ly/3kKIb9a

    N-acetyllactosamine (lacNAC) reverts human TIL anergy ex vivo.

    N-acetyllactosamine (lacNAC) reverts human TIL anergy ex vivo.
    Hello In this edition of the podcast I will discuss a paper published by Demotte and collaborators published this year in the journal Immunity "Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes" vol 28, pag 414 of April 2008. In this paper the authors show that LacNAC can compete for galectin-3 binding freeing TCR from TIL to colocalize with CD8 and allow the recovery of efector functional on ex vivo freshly isolated TIL from ovarian cancer and gastric cancer. See you next time.
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