crispr gene editing

On the show today, the Food and Drug Administration expanded its approval for CRISPR gene-editing therapies. We look at the affordability of these treatments, which can cost well into the millions of dollars. Plus, is bad marketing stunting health tech companies? More on how startups can up their game. But first, at this week’s World Economic Forum in Davos, Switzerland, there were 32 scheduled events devoted to AI. When they weren’t comparing private jets, business executives were busy asking, “How do you make money off AI?” Marketplaces’ Lily Jamali is joined by Christina Farr, a health tech investor at OMERS Ventures, for her take on these stories.

Show Notes:

0:00 Quick vaccine passports update

17:15 China's massive tech crackdown: reasons, ramifications, & more

37:37 How will large firms & institutional investors react to the CCP's recent regulatory moves, mechanics of delisting public companies

41:25 CRISPR breakthrough, future possibilities

50:18 Taking the right approach to climate change with respect to population growth & consumption, carbon markets, practical solutions

1:06:03 Quentin Tarantino's approach & impact on Sacks, Chamath's poker story

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Referenced in the show:

NYT - N.F.L. Sets Stiff Penalties for the Unvaccinated, Jolting Teams

https://www.nytimes.com/2021/07/23/sports/football/nfl-vaccination-policy.html

WSJ - Google, Facebook to Require Vaccinations for On-Campus Workers

https://www.wsj.com/articles/google-to-require-vaccinations-for-on-campus-workers-11627491628

AP - Biden orders tough new vaccination rules for federal workers

https://apnews.com/article/lifestyle-joe-biden-business-health-travel-a1670ffa08f1f2eab42c675d99f1d9ad

Bloomberg - NYC’s Top Dining Rooms Will Start Requiring Proof of Vaccination

https://www.bloomberg.com/news/articles/2021-07-29/danny-meyer-restaurants-start-requiring-vaccination-for-indoor-dining

NBC Chicago - Scams and Fake Vaccination Cards: Lollapalooza Put To The Test

https://www.nbcchicago.com/news/local/scams-and-fake-vaccination-cards-lollapalooza-put-to-the-test/2569984/

WSJ - Covid-19 Pill Race Heats Up as Japanese Firm Vies With Pfizer, Merck

https://www.wsj.com/articles/covid-19-pill-race-heats-up-as-japanese-firm-vies-with-pfizer-merck-11627205403

WSJ - ByteDance Shelved IPO Intentions After Chinese Regulators Warned About Data Security

https://www.wsj.com/articles/bytedance-shelvedipo-intentions-after-chinese-regulators-warned-about-data-security-11626078000

Reuters - ByteDance founder tells staff he’s shifting away from CEO’s daily work -sources

https://www.reuters.com/business/tiktok-owner-bytedances-2020-revenue-soars-net-loss-45-bln-memo-2021-06-17

Bloomberg - China Weighs Unprecedented Penalty for Didi After U.S. IPO

https://www.bloomberg.com/news/articles/2021-07-22/china-is-said-to-weigh-unprecedented-penalty-for-didi-after-ipo?srnd=cybersecurity

Seeking Alpha - SoftBank's Didi stake loses $4B in value amid regulatory crackdown

https://seekingalpha.com/news/3719027-softbanks-didi-stake-loses-4b-in-value-amid-regulatory-crackdown

Bloomberg - China Education Tycoon Loses $15 Billion as Shares Tumble

https://www.bloomberg.com/news/articles/2021-07-26/chinese-education-tycoon-loses-15-billion-as-shares-plunge-98

Bloomberg - China to Overhaul Education Sector ‘Hijacked by Capital’

https://www.bloomberg.com/news/articles/2021-07-25/china-to-overhaul-private-education-sector-hijacked-by-capital

BBC - Tencent shares slide after Beijing crackdown on music rights

https://www.bbc.com/news/business-57966023

NPR - He Inherited A Devastating Disease. A CRISPR Gene-Editing Breakthrough Stopped It

https://www.npr.org/sections/health-shots/2021/06/26/1009817539/he-inherited-a-devastating-disease-a-crispr-gene-editing-breakthrough-stopped-it

Science Magazine - CRISPR creates first genetically modified marsupials

https://www.sciencemag.org/news/2021/07/crispr-creates-first-genetically-modified-marsupials

As 2019 draws to a close, we enlisted the help of two NPR science correspondents — Nell Greenfieldboye and Joe Palca — to look back on some of the biggest science stories of the past 10 years. Follow host Maddie Sofia on twitter @maddie_sofia. Email the show at shortwave@npr.org.

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Today we have Carl Zimmer on the podcast. Zimmer reports from the frontiers of biology, where scientists are expanding our understanding of life. Since 2004 he was written about science for the New York Times, where his column “Matter” has appeared weekly since 2013. Zimmer has won many awards for his work, including the Stephen Jay Gould Prize, awarded by the Society for the Study of Evolution to recognize individuals whose sustained efforts have advanced public understanding of evolutionary science. Zimmer is the author of thirteen books about science. His latest book is She Has Her Mother’s Laugh: The Power, Perversions, and Potential of Heredity.   In this episode, we discuss:   - The difference between genetics and heredity   - The perils and promises of gene-editing technologies   - The potential for unethical application of emerging genetics findings   - The potential for misuse of the genetics of intelligence in education   - The potential perils of genetically modified mosquitoes    - The potential perils of genetically modified crops   - The quirky nature of epigenetics   - The existence of “human chimeras”   - The limitations of DNA testing

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With the discovery of a surprising immune response in E coli bacteria, we are facing a new era of freedom from genetic mutations that lead to disease by simply and precisely editing our genes. But there is also a potential dark side to gene editing.

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