ketamine for depression

 Host David Flores welcomes Dr. Steven L. Mandel, President and Founder of Ketamine Clinics Los Angeles, to shed light on the misconceptions and stigmas associated with ketamine therapy. They tackle the widespread misinterpretations of Perry’s autopsy report and its unintended consequences on the public's understanding of ketamine's role in treating mood disorders. Dr. Mandel elucidates the stark difference between the recreational abuse of substances like ketamine and their controlled, therapeutic use, drawing an analogy with alcohol consumption to clarify this distinction. Throughout the episode, they explore various aspects of ketamine therapy, discussing its effectiveness, the risks associated with recreational use, and its application in addiction treatment. Insights into the high standards maintained in ketamine clinics and the impactful patient stories further illuminate the significant, life-changing breakthroughs achieved through this treatment, often in combination with psychotherapy. This enlightening conversation aims to dispel myths and educate listeners on the safe and responsible use of psychedelics like ketamine in medical settings, emphasizing their transformative potential when used correctly. 
 

It’s the ketamine episode you’ve been waiting for! Ketamine is not technically a (classic) psychedelic, yet it behaves like one. Many researchers and scientists in the psychedelic space consider it to be a psychedelic, and are applying the psychedelic assisted psychotherapy model to its use.

This episode is a treasure trove of information for those who are considering ketamine for treatment, and those who want to learn more about this “chameleon” drug. Delivering this information is Dr. Kyle Greenway; a highly respected ketamine researcher and psychiatrist. He keeps a low profile, so it was truly special to have him on the show.

Dr. Greenway is a psychiatrist and assistant professor at McGill University. He completed a research fellowship at Imperial's psychedelic research centre and co-led the development of two academic clinics utilizing ketamine in treatment-resistant depression. These clinics are amongst the only services in the world to provide ketamine-assisted therapy in public healthcare systems.

Beyond his academic accolades, Dr. Greenway is very fun to learn from. I promise you that even though this conversation is highly academic, we had a lot of fun talking about serious subject matter.

Topics covered:

• What is Ketamine? & its history
• Why Ketamine is so dose-dependent
• Why Ketamine is a “chameleon” drug
• How Ketamine started to be used for mental health conditions
• Ketamine vs classic psychedelics
• The “after glow” / anti-depressive effect
• Risks with abusing ketamine, such as “ketamine bladder”
• Who and what ketamine is effective for
• Why the “inner healing intelligence” might be harmful
• What a ketamine treatment protocol looks like
• The future of psychedelic assisted therapy and ketamine

Show Links:

• Microdosing Psychedelics - free workshop - SAVE YOUR SEAT!
• Earth Runners Earthing Sandals - LANA to save 10%
• Research paper on Imprinting
• Show Notes

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DISCLAIMER: Modern Psychedelics does not endorse or support the illegal consumption of any substances. This show is meant for entertainment purposes only. The thoughts, views and opinions on this show should not be taken as life advice, medicinal advice, or therapeutic guidance. 

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This episode was  produced in collaboration with FWI Media. Check out their beautiful work!

Please support the show and leave a review  if this episode sparked something within.
 

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DISCLAIMER: Modern Psychedelics does not endorse or support the illegal consumption of any substances. This show is meant for entertainment purposes only. Modern Psychedelics does not sell or promote the sale of any illegal substances. The thoughts, views and opinions on this show should not be taken as life advice, medicinal advice, or therapeutic guidance. 

We've talked about therapy, we've talked about antidepressants... but today we’re talking about a totally different type of treatment for depression: Ketamine.

When I say that, you might think, WOAH, that’s an anesthetic. Or, that’s a party drug. But here's how it relates to mental health - there are now places you can go, doctors you can go to, to get a Ketamine infusion for your depression.

And this is fascinaing to me. Because I am all for anything that can be proven to help people’s brains. Ketamine - because of its use as an anesthetic, is legal for medicinal use. And has been since the 1960s.

My guests today are Dr. Steven Mandel and Sam Mandel, the founders of Ketamine Clinics Los Angeles!

Dr. Mandel has been using Ketamine to treat patients for over 40 years, as a board-certified anesthesiologist. He’s also a founder of the American Society of Ketamine Physicians, Psychotherapists, and Practitioners. Sam Mandel is his son, and the Chief Operating Officer of Ketamine Clinics Los Angeles. They opened the clinic together 7 years, ago, and since then, have administered over 8 thousand treatments.

I loved talking to them about what Ketamine infusions entail, how it actually works on the brain, and how it has helped many of their patients feel SO much better.

You can keep up with Mentally Together on Instagram @mentallytogetherpod. Cassidy's Instagram is @cassidyquinntv, and you can watch the video version of each podcast episode at YouTube.com/cassidyquinn.

Books recommended by Mentally Together guests: https://bookshop.org/lists/mentally-together

Mentally Together is a creation from Cassidy Quinn in collaboration with Coba.fm.

You can keep up with Mentally Together on Instagram @mentallytogetherpod. Cassidy's Instagram is @cassidyquinntv, and you can watch the video version of each podcast episode at YouTube.com/cassidyquinn.

Books recommended by Mentally Together guests: https://bookshop.org/lists/mentally-together

Psychedelic-assisted interventions appear to be all the rage these days. Though there are many psychedelic evangelists I wanted to find a credible medical resource to discuss these treatments. Deep gratitude to my friend Ron Purser who introduced me to my esteemed guest, Sylver Quevedo, MD, a pioneer in integrative family and internal medicine, assistant professor of medicine at Stanford and UCSF, co-Founder of Polaris Insight Center for Ketamine-assisted psychotherapy, and Principle Investigator in the FDA clinical trials on MDMA for Post-traumatic Stress Disorder. Our conversation was enlightening and it was fascinating to hear about Dr. Quevedo’s long history of work in public health, his devotion to providing medical care for indigenous populations in the American Southwest and Africa, and his enduring personal and professional interest in clinical use of psychedelic plant medicines. He beautifully explicates the biologic mechanisms of psilocybin, MDMA, ketamine, ayahuasca, mescaline and how these substances differ in effect and usefulness in psychotherapy. Dr. Quevedo is limited in discussing outcomes of the current phase 3 MDMA trials but he shared results of previous MDMA for PTSD trials, as well as use of psilocybin-assisted psychotherapy for end-of-life anxiety, depression, and ketamine-assisted psychotherapy for suicidal depression and chronic pain. So sit back and enjoy the journey this amazing physician takes us on.

https://www.polarisinsight.com/

https://maps.org Multidisciplinary Association for Psychedelic Studies 

https://clinicaltrials.gov/ NIH MDMA Studies

Sylver Quevedo, MD, Internist Polaris Co-Founder and Medical Director has been in continuous practice of medicine for 40 years and practices nephrology, family, internal, and integrative medicine. He serves as Assistant Professor  at Stanford and UCSF.  He has played pivotal roles in several global health projects, including planning and development of medical and nursing school in Africa. The staff at Polaris Insight Center are dedicated to the ethical and compassionate clinical use of ketamine-assisted, and psychedelic-assisted, psychotherapy. Our founding members are all MAPS (Multi-disciplinary Association for Psychedelic Studies) trained clinicians who have participated in both Phase 2 and Phase 3 clinical trials of MDMA-assisted psychotherapy for PTSD.