metabolic therapies

Maggie Jones was fortunate to establish friendships with the scientists and practitioners who are changing the cancer paradigm and she has become a prominent voice in the metabolic cancer treatment community. This is exactly what she and her husband Brad share with us in this episode.

To view full show notes, more information on our guests, resources mentioned in the episode, discount codes, transcripts, and more, visit https://www.drmindypelz.com/ep184/

Maggie and Brad's life changed when, the month she turned 40, Maggie was diagnosed with terminal cancer and received a prognosis of less than a year. She's been cancer free for three years now and has dedicated her life to sharing the evidence-based treatments that dramatically improved her survival and quality of life

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Please note our medical disclaimer.

In part 2 of this special AMA episode, ketosis expert Dom D’Agostino once again joins Bob Kaplan, Peter’s Head of Research, to discuss the impact of ketosis on various chronic diseases as well as the latest research on the metabolic management of cancer. Dom also discusses the numerous applications of hyperbaric oxygen therapy, provides insights into the application of ketosis on female health and performance, and much more. If you’re not a subscriber and listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode on your private RSS feed or on the website show notes page.

We discuss:

• Update on Dom’s Press-pulse therapeutic strategy for the metabolic management of cancer [2:05];
• Potential role for vitamin C in cancer treatment [12:45];
• Glutamine targeting in cancer therapy—evidence that the mitochondria in cancer are damaged? [17:45];
• Can a ketogenic diet lessen the toxicity of cancer therapies? [24:45];
• 3BP—a promising agent in cancer therapy [26:45];
• The relationship between cancer and ketogenic diets [29:30];
• Hyperbaric oxygen therapy (HBOT)—primer, protocols, and therapeutic uses [33:30];
• Is there a potential role for HBOT in treating COVID-19 patients? [44:15];
• Non-cancer applications of HBOT [47:30];
• The inverse relationship between glucose and ketones [50:30];
• Is a ketogenic diet appropriate for type 1 diabetics? [54:00];
• How ketosis may reduce the risk for Alzheimer’s disease and Parkinson’s disease [1:00:30];
• Ketosis for females—considerations, fertility, performance, and the latest research [1:11:00];
• Low-carb diets during pregnancy and postpartum [1:17:00];
• A high-protein diet to counteract common hormonal issues associated with the ketogenic diet [1:21:15];
• Nutritional tips for remaining metabolically flexible [1:22:45];
• What is one belief Dom has changed his mind about? [1:26:45];
• In utero experiments, and other interesting questions Dom wants to explore [1:29:45];
• The anti-catabolic effect of ketones, cancer cachexia, and nutritional interventions for cancer patients [1:38:30];
• What is the one interesting experiment Dom would do if money and time were not a barrier? [1:46:25]; and
• More.

Learn more: https://peterattiamd.com/

Show notes page for this episode: https://peterattiamd.com/domdagostinoama02/

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In this episode, Thomas Seyfried, a cancer researcher and professor of biology at Boston College, discusses a controversial view of cancer as a mitochondrial metabolic disease. Many topics related to the causes, treatments, and prevention of cancer are covered in this in-depth conversation.

We discuss:

• How Tom got interested in cancer research [9:00];
• Calorie-restricted ketogenic diets, fasting, and epileptic seizures [18:30];
• Otto Warburg and the Warburg effect [30:45];
• Germline mutations, somatic mutations, and no mutations [42:00];
• Mitochondrial substrate level phosphorylation: Warburg’s missing link [51:30];
• What is the structural defect in the mitochondria in cancer? [1:02:00];
• Peter’s near-death experience with the insulin suppression test while in ketosis [1:06:30];
• Insulin potentiation therapy and glutamine inhibition [1:13:15];
• The macrophage fusion-hybrid theory of metastasis [1:39:30];
• How are cancer cells growth dysregulated without a mutation? [1:47:00];
• What is the dream clinical trial to test the hypothesis that we can reduce the death rates of cancer by 50%? [2:03:15];
• How can the hypothesis be tested rigorously that structural abnormalities in the mitochondria impair respiration and lead to compensatory fermentation? [2:26:30];
• Case studies of GBM survivors [2:32:45]; and
• More.

Learn more at www.PeterAttiaMD.com

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