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    neuroinflammation

    Explore " neuroinflammation" with insightful episodes like "Episode 151: What is the gut-brain connection and why does it matter for our kids?", "117: Brendan Vermeire, Mental & Metabolic Health Scientist & Clinical Researcher: Understanding Functional Mental Health & Neuroinflammation for Optimal Sleep & Wellbeing.", "Mit einer Neuropsychologin über neurologische Tests, Gehirnentzündungen und Brainfog bei Long Covid und ME/CFS #81", "55. Mental health and Lyme disease with Dr. Brian Fallon" and "The Top Causes of Mental Health with Brendan Vermeire" from podcasts like ""Natural Super Kids Podcast", "The Sleep Is A Skill Podcast", "Faszination Fatigue", "Looking at Lyme" and "The Root Cause Medicine Podcast"" and more!

    Episodes (25)

    Episode 151: What is the gut-brain connection and why does it matter for our kids?

    Episode 151: What is the gut-brain connection and why does it matter for our kids?

    The rise in mental health issues among children is concerning, but did you know that it's tightly woven with changes in their gut microbiome? In this episode, I will share with you how nurturing a diverse microbiome can balance neurotransmitters and enhance mental well-being to improve mood, sleep, behaviour, and more. 

    In this episode, we will delve into:

    • Understanding what the gut-brain connection is;
    • What the gut-brain connection means for our children's overall health and well-being;
    • Steps we can take to improve our children's mental health through the gut-brain connection, including dietary, lifestyle, and nutrient suggestions;
    • I will share more information on the gut and why our microbes are so important for brain health;
    • What affects microbiome diversity in our children;
    • The link between gastrointestinal complaints & mental health disorders;
    • I share more information on neuroinflammation and what we can do to reduce this;
    • I delve into the topic of psychobiotics and what specific strains have been researched in connection to improving mood, sleep, and mental health outcomes.
    • Plus my favourite herb & nutrient for gut-brain connection.


    Episode Links:



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    117: Brendan Vermeire, Mental & Metabolic Health Scientist & Clinical Researcher: Understanding Functional Mental Health & Neuroinflammation for Optimal Sleep & Wellbeing.

    117: Brendan Vermeire, Mental & Metabolic Health Scientist & Clinical Researcher:  Understanding Functional Mental Health & Neuroinflammation for Optimal Sleep & Wellbeing.

    Join us in this captivating episode as we dive into the fascinating world of functional mental health and neuroinflammation with Brendan Vermeire, a renowned Mental and Metabolic Health Scientist & Researcher and the creator of The Mental M.A.P.™️

    Discover Brendan's gripping personal journey that ignited his profound interest in the field of mental health. We explore the crucial role of microglial cells and the link between mental health and insomnia.  

    Brendan emphasizes the impact of lifestyle choices on our mental health struggles and shares the secrets to nurturing your fundamentals for optimal mental well-being.

    In addition, Brendan unveils his own sleep habits, providing valuable takeaways for restorative sleep and optimal mental health. Take advantage of this informative and engaging discussion!

     

    BIO:

    Brendan is a Mental and Metabolic Health Scientist & Researcher, Functional Medicine Educator, Writer, and Speaker. He is a Board-Certified Holistic Health Practitioner, Master Nutrition Coach, Master Personal Trainer, USAW Sports Performance Coach, and Crossfit Trainer.

    He began his career as a personal trainer and nutrition coach at the age of 18 after disappointingly being medically discharged from the United States Navy Seal training pipeline due to an injury.  After being exposed to the power of functional lab testing in the start of his career, he began intensely pursuing that as a career path which has led him to be widely regarded as one of the top leading experts in Metabolic Health and Functional Education.

    He is the proud owner and founder of the Metabolic Solutions Institute for Functional Health and Fitness Practitioners and the creator of the Functional Mental Health Practitioner Certificate Course. He is also the founder of the Metabolic Solutions Research & Education Foundation, a not-for-profit foundation dedicated to ‘changing the way the world views mental health’ through advancing the science of Mental Health Dysfunction. He is also the creator of The Mental M.A.P.™, a cutting-edge Lab Panel for Mental Health.

    When he’s not educating doctors/practitioners/professionals, helping clients overcome their most severe health struggles, or producing cutting edge scientific education, Brendan enjoys all things fitness and is probably working out. He also enjoys anything in nature and any activities that expand his heart, mind, and soul.

    To learn more about Brendan, please visit: www.metabolicsolutionsllc.com
     


    SHOW NOTES: 

    🧠 What made Brendan interested in functional mental health and neuroinflammation?

    🧠 Exploring the crucial role of microglial cells

    🧠 Link between neuroinflammation and Insomnia

    🧠 Insights into the sleep challenges faced by many Americans

    🧠 Brendan addressed that lifestyle behaviors play a significant role in people's struggles

    🧠 What are the foundational elements that coaches and practitioners should motivate their patients to implement

    🧠 How to nurture your fundamentals for mental well-being

    🧠 Objective assessment of brain cell dysfunction

    🧠 Reinforcing objective data 

    🧠 Benefits of Mental M.A.P testing

    🧠 What could we learn from Brendan's sleep-night routine?

    🧠 Learn more about The Mental M.A.P.™️ www.metabolicsolutionsllc.com


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    GUEST LINKS:

    Website: www.metabolicsolutionsllc.com

    Instagram: the_holistic_savage

    Linkedin: https://www.linkedin.com/in/brendan-vermeire-23754693/


    DISCLAIMER:

    The information contained on this podcast, our website, newsletter, and the resources available for download are not intended as, and shall not be understood or construed as, medical or health advice. The information contained on these platforms is not a substitute for medical or health advice from a professional who is aware of the facts and circumstances of your individual situation.

    Next Steps To Upleveling Your Sleep - 

    Website: https://www.sleepisaskill.com/    

    ‘Sleep Obsessions’ Monday Newsletter: https://www.sleepisaskill.com/newsletter

    8-Week Wearable Group “Optimize Your Sleep” Program: https://www.sleepisaskill.com/optimize

    Sleep Is A Skill Podcast: https://www.sleepisaskill.com/podcasts

    LinkedIn: https://www.linkedin.com/in/mollie-eastman-sleep-is-a-skill-82531825/

    Instagram: https://www.instagram.com/mollie.eastman

    TikTok: https://www.tiktok.com/@sleepisaskill 

    Facebook: https://www.facebook.com/sleepisaskill/

    Twitter: https://twitter.com/SleepIsASkill

    YouTube: 

    https://www.youtube.com/channel/UCy-IU372xapHLvXnZRbXU7A

    55. Mental health and Lyme disease with Dr. Brian Fallon

    55. Mental health and Lyme disease with Dr. Brian Fallon

    In this podcast, Sarah talks with Dr. Brian Fallon about the cognitive and mental health manifestations of Lyme disease, and about some of his past and future research collaborations. Dr. Fallon is a physician, researcher, author, and Director of the Lyme and Tick-borne Diseases (TBD) Research Center and the Lyme and TBD Clinical Trials Coordinating Center at the Columbia University Irving Medical Center in New York City. His work is focussed on the neuropsychiatric and persistent symptoms related to Lyme disease. 

    The Top Causes of Mental Health with Brendan Vermeire

    The Top Causes of Mental Health with Brendan Vermeire
    The Root Cause Medicine Podcast is created by Rupa Health, the best way to order, track & manage results from 30+ lab companies in one place for free. The Root Cause Medicine Podcast is a weekly one-on-one conversation with renowned medical experts, specialists, and pioneers who are influencing the way we look at our health and wellbeing. This week we’re joined by Brendan Vermeire, Functional Medicine Consultant and Founder of Metabolic Solutions. In this episode, Brendan Vermeire talks about mental health, from depression, anxiety, and neuroinflammation to dementia and Alzheimer's. Brendan is a mental and metabolic health researcher, functional medicine educator, board-certified holistic practitioner, personal trainer, writer, speaker, and host of The Holistic Savage podcast. He is also the owner and founder of the Metabolic Solutions Institute for Functional Health and Fitness Practitioners and the Metabolic Solutions Research & Education Foundation, a not-for-profit foundation dedicated to "changing the way the world views mental health" through advancing the science of mental health dysfunction. Key Takeaways: Debunking the classic psychiatric narrative The current model of mental health treatment in the psychiatric world offers limited treatment options, such as pills or therapy, with little consideration for underlying causes of inflammation or other factors that could contribute to mental health issues. As a result, mental health practitioners like Brendan focus on studying more predominant theories, such as cytokine or neurotrophic ones. Inflammation and mental health symptoms Brendan represents inflammation as "the cleansing fire the immune system uses to fight off pathogens and remodel tissues." Inflammation can be driven by anything, including food, mold, viruses, or pathogens. Most people aren't aware of it, but the average American is inflamed at a low chronic meta-level, which drives the chronic disease epidemic, depression, anxiety, and other mental health issues. The role of neuroplasticity in mental health Neuroplasticity refers to the brain's ability to change and adapt in response to experiences and environmental factors. It is a crucial process that underlies learning, memory formation, and the recovery of function after brain injury. Interventions that promote neuroplasticity, such as cognitive-behavioral therapy, mindfulness-based practices, and physical exercise, effectively improve symptoms of depression, anxiety, and other mental health conditions, which may help to promote positive changes in brain structure and function. How does the microbiome affect mental health? Changes in the microbiome can affect our mental health. Multiple research suggests that the microbiome composition can impact the brain through various mechanisms, including neurotransmitter regulation, inflammation, and immune system modulation. Additionally, some studies have found that a diverse and healthy microbiome is associated with better mental health outcomes. The Mental M.A.P. The Mental M.A.P. (Microglial Activation Profile) is a sophisticated lab panel that assesses the likelihood of microglial activation and neuroinflammation by evaluating multiple serological blood, urine, and even stool markers, as well as other core functions like methylation and nutrient imbalances. Also, check out Brendan’s recommended lab testing: The Mental M.A.P., C-reactive protein test, Homocysteine, Thromboxane B2, and Kryptopyrrole Order these tests through Rupa Health - https://www.rupahealth.com/reference-guide

    COVID-19 & male fertility...with Rhiannon Hardingham

    COVID-19 & male fertility...with Rhiannon Hardingham
    With the global epidemic of COVID-19 and the increasing number of infections, little is known about how COVID-19 affects the male reproductive system during acute infection or after recovery. In this podcast, naturopath and nutritionist Rhiannon Hardingham discusses the recent evidence and clinical approaches for prevention, acute management, and post-viral recovery, specific to male reproduction.

    Want Energy Like a 2 Year Old Again?

    Want Energy Like a 2 Year Old Again?

    🐱‍🏍DO YOU REMEMBER WHEN YOU WERE YOUNG…👣 AND YOU RAN EVERYWHERE YOU WENT…🏃‍♀️ AND YOU FELT GOOD DOING IT? 💃How would you feel today, if you could have energy like that again? What would it look like? What would you do? What would you do differently with your new-found energy? What about your mental energy… have you noticed that slowing down too? In today’s episode, we are going to explore some barriers that… have been… and likely… still are blocking your physical and emotional energy.

     🌟HIGHLIGHTS🌟

    ✅  02:41   Feeling Sluggish?
    ✅  08:19   What is causing low energy issues?
    ✅  10:20   Been diagnosed with chronic fatigue syndrome?
    ✅  12:23   The root cause of Chronic Fatigue
    13:40    Dr. Brian's Mantra: Inflammation is Synonymous with Immunity
    15:35    Want energy like a 2 year old?

    Dr. Brian's mantra:
     Inflammation is Synonymous to Immunity 

     Dr. Brian is a functional medicine practitioner with a subspecialty in epigenetics and nutrigenomics
    If you have a question for Dr. Brian, please contact him at https://drbriangbrown.com/question

    And if you are ready to take your life, performance, mood, and energy to the highest potential check out his FREE 5 day Gene Hack Boot Camp: https://drbriangbrown.com/genehack/bootcamp


    067: Dr. Richard Bedlack and Dr. Wissam Mansour of the Duke ALS Clinic Explain the Connection Between ALS and Sleep and Discuss Research Efforts Into ALS Reversals

    067: Dr. Richard Bedlack and Dr. Wissam Mansour of the Duke ALS Clinic Explain the Connection Between ALS and Sleep and Discuss Research Efforts Into ALS Reversals

    🧬 How Dr. Richard Bedlack came to ALS research and why he developed a multi-disciplinary team at Duke for ALS care.

    🧬 Dr. Wissam Mansour’s journey from pulmonary critical care, to sleep training, to joining Dr. Bedlack’s ALS team at Duke.

    🧬 Exploring the possible connection between ALS and sleep disorders

    🧬 Sleep-related breathing disorders, insomnia, and sleep movement disorders in ALS patients

    🧬 How sleep disorders can potentially impact quality of life and length of life in people with ALS

    🧬 The genetic factors that link ALS, sleep-wake cycles, and parts of the brain involved in sleep.

    🧬 Screening ALS patients for general sleep problems and dealing with ALS-specific sleep disorders

    🧬 How accumulating CO2 levels during an ALS patient’s sleep can cause other serious health issues

    🧬 The importance of proactive measures for treating sleep problems in ALS patients

    🧬 Demystifying the types of non-invasive ventilation options for people with ALS 

    🧬 Dr. Bedlack discusses his experience with alternative and off-label therapies for ALS 

    🧬 Creating the ALSUntangled program to investigate alternative therapies and provide patients with a better understanding of treatment options

    🧬 Dr. Bedlack’s research into ALS reversals and patients who have completely recovered from the disease

    🧬 How melatonin, a supplement usually taken for sleep regulation, can suppress neuroinflammation that can be relevant to ALS

    🧬 The potential link between poor sleep quality and other disorders like Parkinson’s and ALS

    🧬 The far-reaching impacts of ALS on sleep, both for the patients and their families

    🧬 A discussion on the value of wearables to track sleep metrics for ALS patients

    🧬 The variety of ALS symptoms that can affect sleep quality

    🧬 Dr. Bedlack and Dr. Mansour share their personal sleep routines and what is on their nightstands right now

    GUEST BIOS: 

    Dr. Richard Bedlack is a Professor of Neurology at Duke and Director of the Duke ALS Clinic. He has won awards for teaching and patient care, including best Neurology teacher at Duke, Health Care Hero, Strength Hope and Caring Award, America’s Best Doctor, the American Academy of Neurology Patient Advocate of the Year, and the Rasmussen ALS Patient Advocate of the Year. He has received ALS research grants, participated in ALS clinical trials, and published more than 100 ALS articles.  He is the leader of the international ALSUntangled program which utilizes social networking to investigate alternative and off-label treatment options for patients with ALS, and the leader of the ALS Reversals program which attempts to understand why some people with ALS recover from it, and to make this happen more often. He lives in Durham, North Carolina with his wife Shelly and two mischievous cats.

    Dr. Wissam Mansour is an Assistant Professor of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine at Duke University. His clinical and research interests are focused on sleep-related breathing disorders and neuromuscular lung disease. He is particularly interested in advancing our understanding of the pathophysiological mechanisms leading to sleep-disordered breathing and allowing for a more targeted treatment approach.

    EPISODE LINKS:

    Website:

    www.dukealsclinic.org

    Email: 

    Richard.bedlack@duke.edu

    wissam.mansour@duke.edu

    Next Steps To Upleveling Your Sleep - 

    Website: https://www.sleepisaskill.com/    

    ‘Sleep Obsessions’ Monday Newsletter: https://www.sleepisaskill.com/newsletter

    8-Week Wearable Group “Optimize Your Sleep” Program: https://www.sleepisaskill.com/optimize

    Sleep Is A Skill Podcast: https://www.sleepisaskill.com/podcasts

    LinkedIn: https://www.linkedin.com/in/mollie-eastman-sleep-is-a-skill-82531825/

    Instagram: https://www.instagram.com/mollie.eastman

    TikTok: https://www.tiktok.com/@sleepisaskill 

    Facebook: https://www.facebook.com/sleepisaskill/

    Twitter: https://twitter.com/SleepIsASkill

    YouTube: 

    https://www.youtube.com/channel/UCy-IU372xapHLvXnZRbXU7A

    AAIC 2021 – COVID-19 Impacts on Cognitive Health + Pancreatic Cancer Blood Test

    AAIC 2021 – COVID-19 Impacts on Cognitive Health + Pancreatic Cancer Blood Test

    In this episode, Ayesha discussed a presentation at this year’s Alzheimer’s Association International Conference (AAIC) 2021 about the impacts of COVID-19 on cognitive health. The study, conducted at New York University Langone Health, found that in cognitively normal COVID-19 patients that experienced the neurological symptom of confusion due to toxic-metabolic encephalopathy (TME), levels of serum biomarkers associated with neuroinflammation, neuronal injury and Alzheimer’s disease (such as phosphorylated Tau 181 and neurofilament light protein) were higher than in patients that did not have TME. The strong correlation of these serum biomarkers with the presence of neurological symptoms in COVID-19 patients suggest that COVID-19 patients could experience an acceleration of AD/ADRD symptoms and pathology.

    Ayesha also discussed another story about serum biomarkers for the early detection of pancreatic cancer. Immunovia, a Swedish biotech firm, has developed a nine-panel biomarker blood test that can be used for the detection of pancreatic in early stages. The company’s American subsidiary, located in Massachusetts, received approval for the test early this month and the Massachusetts Department of Public Health has already begun using it to test patients for the deadly cancer. The test evaluates a combination of immunoregulatory and tumor biomarkers. Early detection of pancreatic cancer is a significant unmet clinical need because the cancer is typically diagnosed in late stages when treatment options are limited and the disease is difficult to treat.

    AAIC 2021: Insights into COVID-19 Impacts on Cognitive Health

    Immunovia’s Pancreatic Cancer Blood Test is World’s First for Early Disease Detection

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    Stress, Neuroinflammation and Digestive Issues

    Stress, Neuroinflammation and Digestive Issues

    Show Summary:  “When you're bloated and have a super noisy gut, you might not be making enough enzymes to break down your food because you're stressed out.”


    Stress and digestive issues can create neuro-inflammation. The vagus nerve attaches to every organ in a human body's digestive tract, keeping you in balance and maintaining your homeostasis. But, viruses can potentially hijack the vagus nerve and the immune system depending on how well the body can balance different life stressors.


    The neck area has a direct connection with the brain. When someone has Epstein Barr or food sensitivities, they get swollen lymph nodes. Poor posture and stress can cause tight neck, preventing proper circulation and getting rid of toxins to help the body heal.


    Dr. Jannine Krause, a Naturopathic Doctor, Acupuncturist, and Podcaster, shares how strengthening the parasympathetic system can combat this issue. Listen well as she gives tips and actionable practices on how to start to calm your nervous system to prevent inflammation.


    Important Links

    Gutsy Health Website

    Dr. Jannine Krause Website

    The Health Fix Podcast

    Dr. Jannine Krause TV

    Instagram

    Exceptional Highlight:


    • Stress creates inflammation in the nervous system and we get infections because of it.
    • You can't run from a bear and digest food. The brain literally cannot do that. Your nervous system is either in a parasympathetic state (rest and digest) or it’s in a sympathetic state (fight or flight) but it can’t be in both.
    • Your oral health is related to your systemic health. When your gums keep bleeding or getting cavities, that is related to gut health.

    .


    Show Highlights: 


    The belly is your first brain


    Jannine 3:06


    • We also have all these nerves that are connected, they go all the way down the spine, so can potentially affect every single part of your body, every organ in your body..


    How do we help ourselves with neuro-inflammation?


    Jannine 14:41


    • It's not because we need to calm  the sympathetic nervous system, we need to strengthen the parasympathetic. I'm doing a lot more lifestyle stuff now and working on how we get more calm and there's this great thing called parasympathetic breathing.


    What does food sensitivities have to do with it?


    Jannine 19:46 


    • With food sensitivities, what's happening is we've got two things. One is the neck bottleneck issue here. Part of it is if your neck is dealing with stuff, you're putting food in, your neck’s already inflamed - we're adding histamine. Histamine is a neurotransmitter that comes out in response to inflammation. So if you're struggling with rashes, or hives, or any of that stuff, and you can't figure it out, this could be  neuro-inflammation.

    18. Welcome back! Dr. Theoharides tells us about mast cells and neuroinflammation

    18. Welcome back! Dr. Theoharides tells us about mast cells and neuroinflammation

    Welcome back to Season 2 of the Looking at Lyme podcast. Buckle your seatbelts, because we are going on a science adventure with Dr. Theoharis Theoharides, Professor of Immunology at Tufts University School of Medicine in Boston. Dr. Theoharides has been on the leading edge of mast cell research and recounts the fascinating history and physiology of mast cells. Mast cells have existed for over a hundred million years in many different animals and organisms and are found in all body tissues, including the brain. Mast cells are found in worms, fish, lizards; however, these species do not get allergic reactions. So why are mast cells associated with allergic reactions?


    Dr. Theoharides explains that mast cells became associated with allergies in 1947 when it was discovered that they contained histamine. He describes the activation of mast cells during anaphylaxis as the sudden release of about 50 molecules from inside these cells, followed by a delayed release 6-12 hours later of further, newly synthesized molecules. He reflects on his earlier research showing that the release of these molecules can also occur, not only with allergies, but also due to many pathogenic, environmental triggers (for example, mold), and stress hormones. He notes that triggers such as Borellia or mold can cause the release of only cytokines (not histamine, or tryptase) from the mast cells. Dr. Theoharides also explains that when mast cells are “primed” with interleuken 33, followed by stress hormone release, the mast cells can release more pro-inflammatory cytokines than any other type of immune cell. This massive release of cytokines is referred to as a “cytokine storm”.


    An Ode to The Good Doctor

    An Ode to The Good Doctor

    An Ode to The Good Doctor


    Sometimes being a HappiHuman means we must go through some grief - as I am going though right now.

    So if you’ll oblige me, I’d like to share my candid thoughts from a journal entry I wrote about my beloved Berkeley boy - my first dog who was much, much more than that.

    My intention in sharing these private moments is not to make you sad or cry or conjure up hurtful memories of your own. Rather, my intention is to open my heart in the hopes that others will open theirs.

    We must remember that love is the foundation upon which all of humanity stands. And with all the craziness and challenges humanity has faced this past year, I think we could all use this reminder - especially around the holidays.

    So as we go forth, remember the cherished people and pets in your life. Rekindle lost connections. Keep your heart open. And return to being human.

    Don’t procrastinate about feeling better…take action and invest in your health.

    Why not turbo-charge their brainpower on my blog now: https://bit.ly/2WmB09X

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    A reminder that this content is not intended to substitute professional medical advice. You should always seek the advice of a medical practitioner for your unique case.


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    More Crucial Brain Foods your Child Needs

    More Crucial Brain Foods your Child Needs

    Your child’s brain requires certain nutrients at the right stages of life to help them develop properly.

    In our most recent post, we introduced you to six nutrients that are crucial to the growth and development of your child’s brain. Because the brain health of our kids is so crucial, this week, we’d like to continue exploring a few more.

    We all know now that nutritious food builds strong bodies. But did you know that we need brain food too?

    Unsurprisingly kids who are bored, restless, inattentive and sleepy or who have a bad memory are usually those who have poor eating habits. By choosing the right brain food, kids can help ensure better academic performance and concentration.

    Our brains take up only 2% of our body weight yet consume nearly 20% of our body’s energy. Eating “brain food” improves kids’ moods, elevates learning and concentration, and sharpens memory and attention.

    The Standard American Diet falls short. It is devoid of nutrients, yet filled with sugary & fatty neuro-toxins that do nothing positive for our bodies or brains.

    As we did with the last blog, we will include some foods in which these nutrients can be found and what benefits they provide. Then we’ll offer up some power foods that contain several of the key nutrients your child’s brain needs.

    I get that it can be hard to feed a child - especially if they happen to be picky or only want to eat certain foods or textures. Hopefully, this list of power foods is the exact tool you need!

    Don’t procrastinate about feeling better…take action and invest in your brain.

    Why not turbo-charge their brainpower on my blog now: https://bit.ly/33e0vhu

    My Social Media:
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    A reminder that this content is not intended to substitute professional medical advice. You should always seek the advice of a medical practitioner for your unique case.

    https://linktr.ee/kellyaiello |

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    Six Crucial Brain Foods Your Child Needs

    Six Crucial Brain Foods Your Child Needs

    By the time your child is 3, your toddler’s brain will have tripled in size since birth. This is the biggest learning curve of his or her life and a time when his or her brain is developing trillions of connections.

    At the same time, he or she is increasingly physically active and developing his social skills too. With all that going on, our children need a wide range of food to aid in rapid brain development.

    “There is pretty solid evidence that children who are hungry are not able to focus, so they have a low attention span, behavioural issues, discipline issues in the school,” said Sibylle Kranz, an associate professor of kinesiology and a registered dietitian nutritionist in the Curry School. “Having children who are well-fed and not hungry makes a difference in their individual performance, and also how much they are contributing to or disrupting the classroom situation.”

    Scientists have found around 45 nutrients that are key to brain health, including things like protein, zinc, iron, choline, folate, iodine, vitamin A, vitamin D, vitamin B6, vitamin B12, and omega-3 fatty acids.

    “From a neuroscientist’s perspective, food is really fundamentally important for brain health, because our brains literally run on nutrients,” says Lisa Mosconi, director of the Weill Cornell Women’s Brain Initiative.

    By targeting a few food groups and experimenting with new ways of preparing them, fuelling your family’s brain growth can be easier than you might think.

    Don’t procrastinate about feeling better…take action and invest in your brain.

    Why not turbo-charge their diet with these six easy ways to boost your toddler’s brain power now on my blog: https://bit.ly/3paD6H7

    At HappiHuman.com, we pride ourselves on being able to support everyone’s optimal health - regardless of whether you are a TBI survivor, struggle with a mental health issue, wish to improve cognitive function or simply want to optimize your weight and age gracefully and reduce the chance of disease.

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    A reminder that this content is not intended to substitute professional medical advice. You should always seek the advice of a medical practitioner for your unique case.

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    44 - Preclinical Testing Part 2: Alzheimer's Disease August 2020

    44 - Preclinical Testing Part 2: Alzheimer's Disease August 2020

    You'll hear about some big topics in Alzheimer's disease research in this episode! Ellen covers all of the pre-clinical studies from August 2020 testing potential new treatments targeting neuroinflammation, oxidative stress, mitochondria, metabolism, and lipids. This is the second part of three pre-clinical testing episodes this month, check out episode #42 for part 1, and look out for part 3, coming soon!

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    Today's episode was scripted by Melissa Conti and Ellen Koch, hosted and edited by Ellen Koch,  and made possible by an entire team of volunteers behind the scenes.  

    Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic.  

     

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    41 - Neuroinflammation & Glial cells: Alzheimer's Disease August 2020

    41 - Neuroinflammation & Glial cells: Alzheimer's Disease August 2020

    Heather covers papers from August 2020 on the role of neuroinflammation and glial cells on Alzheimer's disease pathology. You'll hear about many papers studying the role of astrocytes and microglia in AD pathology, including how they interact with cell signalling pathways and AD-associated proteins such as amyloid and tau. She ends with a couple papers that aim to understand and/or model neuroinflammation in this disease. We hope you enjoy this episode of AMiNDR! 

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    Today's episode was scripted & hosted by Heather Gerrie, edited by Alexandra Pavel,  and made possible by an entire team of volunteers behind the scenes.  

    Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic.  

     

    https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w  

     

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    Brain Inflammation: What it is and what you can do about it

    Brain Inflammation: What it is and what you can do about it

    One of the most common complaints I hear in my practice is related to brain inflammation, also known as neuroinflammation.

    Most people think of inflammation in relation to arthritic joints, or maybe a sprained ankle or wrist. But did you know your brain can become inflamed, too? Inflammation is usually the body's response to injury and stress such as the redness and swelling that accompanies an injury or infection.

    The problem with inflammation in the brain is that it doesn’t necessarily cause immediate hurt. Instead, symptoms such as brain fog, slow thinking, fatigue, and depression are the hallmarks. The inflammation slows down communication between neurons. This is what causes you to feel foggy, dull, and slow.

    Other common causes of brain inflammation include chronic inflammation in the body, leaky gut, high blood sugar and diabetes, hormone imbalances, hypothyroidism, food intolerances (gluten is a notorious brain inflamer), stress, and brain autoimmunity — a disorder in which the immune system erroneously attacks and damages brain tissue. It is more common than people realize.

    Is your brain inflamed?

    To discover what common complaint this is, to learn the signs your brain may be suffering from inflammation and find out what you can do about it, keep listening!

    At HappiHuman.com, we pride ourselves on being able to support everyone’s optimal health - regardless of whether you are a TBI survivor, struggle with a mental health issue, wish to improve cognitive function or simply want to optimize your weight and age gracefully and reduce the chance of disease.

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    A reminder that this content is not intended to substitute professional medical advice. You should always seek the advice of a medical practitioner for your unique case.


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    Novel Drug Development-Part 2: Alzheimer's Disease June 2020

    Novel Drug Development-Part 2: Alzheimer's Disease June 2020

    Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!  

    Ellen tells you about more papers on drugs in development from June 2020.   These studies encompass those done in vitro or using computational models, but not animal testing. This time around, she will be focusing on papers where the target is tau protein, the cholinergic system, metabolism, mitochondria, neuroinflammation, and autophagy from June 2020! If you're interested in hearing more about treatments for AD, you should also check out our episodes on pre-clinical and clinical testing. 

     

    To receive the list of papers covered (with timestamps), please fill this form: 

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    or by tweeting at us: @AMiNDR_podcast 

    -----------------------------------------------------------------------

    List of sections in this episode:

    (2:14)      Targeting tau          

    (10.13)    Targeting the cholinergic system

    (20:56) Targeting metabolism

    (22:05) Targeting the immune system / neuroinflammation / glia

    (24.45) Targeting mitochondria and/or oxidative stress

    (30.32) Targeting autophagy

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    ----------------------------------------------------------------------- 

    Today's episode was scripted by Mahraz Parvand & Joseph Len Liang-Lee, hosted & edited by Ellen Koch, and made possible by an entire team of volunteers behind the scenes.  

    Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic 

    https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w

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    *About AMiNDR: * 

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    Preclinical Testing - Part 3: Alzheimer's Disease June 2020

    Preclinical Testing - Part 3: Alzheimer's Disease June 2020

    Having trouble keeping up with the literature in Alzheimer's Disease? We are here to help!

    In this episode, Marcia covers papers published in June 2020 on treatment development done on animal models, targeting metabolism, mitochondria, oxidative stress, the gut microbiome, inflammatory pathways, glia, and autophagy. If you are interested in learning more about these pathological events, you should check out our episode on these disease mechanisms, covered by Anusha. We also have a number of episodes dedicated to pre-clinical testing, split by the intended target the cholinergic system, the glutamatergic system, synaptic function, tau, amyloid-beta, cognitive performance, and other multitargeted approaches.  

    Enjoy!

     

    To receive the list of papers covered (with timestamps), please fill this form: 

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    -----------------------------------------------------------------------

    List of sections in this episode:

    (0.57)   Metabolism / lipids

    (3.40)   The gut microbiome

    (5.00)   Autophagy

    (8.10)     Mitochondria

    (10.54)   Oxidative stress

    (18.25)   Inflammatory pathways/ glia

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    -----------------------------------------------------------------------

    Today's episode was scripted and hosted by Marcia Jude, edited by Anusha Kamesh, and made possible by an entire team of volunteers behind the scenes.  

    Our music is from "Journey of a Neurotransmitter" by musician and fellow neuroscientist Anusha Kamesh; you can find the original piece and her other music on soundcloud under Anusha Kamesh or on her YouTube channel, AKMusic 

    https://www.youtube.com/channel/UCMH7chrAdtCUZuGia16FR4w

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    Papers published on Alzheimer's disease in February 2020: Disease Mechanisms

    Papers published on Alzheimer's disease in February 2020: Disease Mechanisms

    About the bibliography:

     

    To receive the list of papers covered (with time-stamps), please subscribe to our mailing list. You can do so by filling this form:   https://forms.gle/jJM9dK4SufapQkey8 

    or by sending us an email at amindrpodcast@gmail.com

     

    List of sections in this episode:

     

    • (1.09) Neuroinflammation/glial cells
    • (14.40) Protein aggregation and post-translation modification (eg: phosphorylation, misfolding), protein-protein interactions
    • (33.31) Cell metabolism (mitochondrial dysfunction, lipids, hormones)
    • (39.00) Neuronal plasticity : cell proliferation, differentiation, maturation, survival + cell death + survival/protection
    • (42.11) Cerebrovascular changes
    • (45.49) Synaptic Transmission
    • (54.33) Autophagy

     

    This episode was curated and produced by a group of volunteers. As we work on producing full-length episodes on ALL the publications from May 2020, we would appreciate your feedback so we can better cater to your needs. You can fill our feedback form here: https://forms.gle/5aq2JyrT6g4P1m8v6 

     

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    If you are interested in joining the team, send us your CV by email. We are specifically looking for help with abstract summary and podcast editing. However, if you are interested in helping in other ways, don't hesitate to apply anyways. 

     

     

    *About AMiNDR: *

    Learn more about this project and the team behind it by listening to our first episode: "Welcome to AMiNDR!"

     

    Our next trial episodes for the month of February 2020: Methods and Models, Risk Factors/Genetics & Biomarkers/Diagnosis, Treatments and Testing, Miscellaneous.

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