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    organophosphates

    Explore " organophosphates" with insightful episodes like "Reflections on Chatting with Lee Laubach" and "Episode 1 - Toxicology" from podcasts like ""K9 Detection Collaborative" and "Network Five Emergency Medicine Journal Club"" and more!

    Episodes (2)

    Reflections on Chatting with Lee Laubach

    Reflections on Chatting with Lee Laubach

    What to listen for:

    “I've had lots of people ask me questions about, should you train your dog to tell you that nothing's there. And I was like, no, you should be good enough…Lee knew there was nothing there. But this is the protocol that we use. So we have to do this. And I absolutely don't believe in training your dog to tell you that odor is not available.”


    Today the Dames of Detection - Robin Greubel, Stacy Barnett, and Crystal Wing - recap their two-part series with Lee Laubach, a professional detection dog handler and Nosework judge. The episodes in this series are #88 and #89. If you haven’t yet, feel free to give those a listen first!


    In today’s chat, Robin, Stacy, and Crystal dive deeper into the world of Nosework, exploring the many external elements that can influence a dog's detection ability. From weather impacts to the significance of training dogs to search for specific odors, they leave no stone unturned. They emphasize the importance of connection both on a dog and trainer level and in community in both Arson dog training and beyond. 



    Key Topics:

    • Intro to Recapping the Chat with Lee (02:24)
    • Becoming a Nosework Judge and Certifying Officials (03:53)
    • Dog Training, Certification, and Weather Impact (08:56)
    • Dog Training and Search and Rescue Work (13:48)
    • Scent Work (19:23)
    • Safety Protocols (23:36)
    • Dog Training and Behavior (28:12)
    • The Importance of Community (33:45)
    • Takeaways (38:15)



    Resources:




    We want to hear from you:


    Jingle by: www.mavericksings.com Instagram: @mavericktastic


    Audio editing & other podcast services by: www.thepodcastman.com Instagram: @the_podcast_man

    Episode 1 - Toxicology

    Episode 1 - Toxicology

    Theme
    Toxicology.

     

    Participants

    Dr Satish Mitter, Pramod Chandru, Samoda Wilegoda Mudalige, Kit Rowe, Rachel Ng, Shreyas Iyer, and Caroline Tyers.


    Discussion 1:
    “Clinical outcomes from early use of digoxin specific antibodies versus observation in chronic digoxin poisoning (ATOM-4)”

    Betty S. Chan, Geoffrey K. Isbister, Colin B. Page, Katherine Z. Isoardi, Angela L. Chiew, Katharine A. Kirby & Nicholas A. Buckley

    https://doi.org/10.1080/15563650.2018.1546010.

    Take-Home Points:

    • The results from this study suggest no benefit from routine use of DigiFab for chronic digoxin toxicity. 
    • Clinical indications for DigiFab use include - cardiac arrest, ventricular arrhythmias or runs of ventricular ectopic complexes and bradyarrhythmias associated with hypotension. 
    • Digoxin levels should only be performed under specific circumstances (not routinely for all patients on digoxin but rather in the context of an AKI or when there is a clinical suspicion of potential toxicity). 
    • When managing chronic digoxin toxicity, correcting any precipitating factors such as volume depletion and electrolyte abnormalities is critically important.
    • Identifying patients at risk of digoxin toxicity (the typical patient is the elderly patient with multiple comorbidities) and drugs that impair digoxin toxicity (NSAIDs and diuretics) is also vital to your overall assessment. 


    Discussion 2:

    Case of malathion (organophosphate) poisoning. 

    • 55-year-old male found unconscious surrounded by chemicals at home. 
    • Developed clear cholinergic toxidrome, tachycardia, and hypotension in ICU.
    • Received atropine on a doubling regimen every 5 minutes: reaching 16mg (and then a continuous infusion) with improvement in his symptoms (including this tachycardia).
    • Infusion weaned after 24 hours with recurrence of hemodynamic instability requiring inotropic support and recommencement of atropine on day 3.
    • Required atropine for 31 days in total. 

     Take-Home Points:

    • The standard, routinely taught presentations for cases do not always apply: this patient was tachycardic rather than bradycardic with his organophosphate toxicity (and this tachycardia responded to atropine). 
    • Atropine for organophosphate toxicity is vital. 
    • Oximes (such as pralidoxime) are occasionally used in the treatment of organophosphate toxicity but should be discussed with toxicology specialists prior to use. 


    Discussion 3:

    “Use of antipsychotics and risk of myocardial infarction: a systematic review and meta‐analysis”

    Zheng-he Yu, Hai-yin Jiang, Li Shao, Yuan-yue Zhou, Hai-yan Shi and Bing Ruan                            

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338104/.


    Take-Home Points:

    • This study suggests an association between antipsychotic use and an increased risk of MI (OR 1.88). 
    • This risk appeared to be greater within the first 30 days of use (when taking daily doses); with the risk decreasing over time. 
    • There was however significant heterogeneity in the data studied. 
    • The recent commencement of an antipsychotic may be worth considering as an added risk factor for ischaemic heart disease in a patient presenting with chest pain.


    Credits:
    The discussions were mediated by ED consultant and toxicologist Dr Satish Mitter and ED consultant Dr Pramod Chandru.

    This episode was produced by the ­­­­Emergency Medicine Training Network 5 with the assistance of Dr Kavita Varshney, Deepa Dasgupta, Cynthia De Macedo Franco, and Paul Scott.


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     ~

    Thank you for listening to our first podcast episode!

    Please send us an email to let us know what you thought.

    You can contact us at westmeadedjournalclub@gmail.com


    See you next time,

    Caroline, Kit, Pramod, Samoda and Shreyas.