Logo
    Search

    Guest Series | Dr. Matthew Walker: The Biology of Sleep & Your Unique Sleep Needs

    enApril 03, 2024

    Podcast Summary

    • Understanding the Importance of Sleep Quality, Quantity, Regularity, and TimingSleep plays a vital role in mental and physical health, and optimizing its quality, quantity, regularity, and timing can significantly improve overall well-being. Identify your optimal sleep pattern and use practical tools to enhance your sleep experience.

      Sleep is essential for both mental and physical health, and the quality, quantity, regularity, and timing of sleep (QQRT) are crucial factors to optimize it. In this six-episode series, Dr. Matthew Walker and Andrew Huberman discuss the importance of sleep, its impact on emotionality, learning, and neuroplasticity, and practical tools to improve sleep. Topics include sleep stages, sleep aids, naps, dreaming, and lucid dreaming. Listeners will learn how to identify their optimal QQRT and apply it for the best possible sleep and alertness. Sponsors Eight Sleep and BetterHelp offer solutions to control sleep environment temperature and access online therapy, respectively. Element provides an electrolyte drink with essential minerals and no sugar.

    • Proper hydration requires electrolytesEnsure proper hydration with Element's electrolytes, consume a packet daily upon waking, during exercise, and in low salt situations.

      Proper hydration goes beyond just drinking enough water. Our bodies require electrolytes for our cells, especially nerve cells, to function properly. Element is an easy way to ensure proper hydration with electrolytes. The speaker recommends consuming a packet of Element in water upon waking, during exercise, and in certain situations where salt intake may be low. Sleep, on the other hand, is a complex process involving both non-REM and REM sleep. Non-REM sleep is further divided into light and deep stages, with deep sleep being the restorative stage. REM sleep, or dream sleep, is the stage where most people believe dreams occur. The ratio of non-REM to REM sleep changes throughout the night, with more deep non-REM sleep in the first half and more REM sleep in the second half. Proper sleep hygiene and understanding the specific pattern of your sleep can lead to better overall health and well-being.

    • Myth of 90-minute sleep cycleFocus on getting enough sleep naturally, without interrupting based on a 90-minute cycle. Create a sleep-conducive environment and practice good sleep hygiene instead.

      The idea of waking up based on a 90-minute sleep cycle to feel more alert is a myth. While sleep does follow a cycle, the length of each cycle varies greatly from person to person. Instead, aim for getting as much sleep as possible without artificially terminating your sleep based on a 90-minute cycle. If you feel like you could go back to sleep after waking up, consider trying to do so, but be cautious not to spend long periods of time awake in bed, as it may negatively impact your association with your bed and sleep. Instead, focus on creating a sleep-conducive environment and practicing good sleep hygiene.

    • Break the association between bed and wakefulnessEngaging in a calming activity in another room can help improve sleep by breaking the brain's conditioned association between the bed and being awake. Understanding sleep stages and their characteristics can aid in developing effective sleep hygiene practices.

      If you're having trouble falling or staying asleep after around 25 minutes, it might be beneficial to get out of bed and engage in a calming activity in another room. This is because your brain may have formed a conditioned association between your bed and being awake. By breaking this association, you can improve your chances of falling and staying asleep. During sleep, the brain goes through various stages, including lighter stages like stage one and deeper stages like stages three and four, as well as REM sleep. In stage two non-REM sleep, sleep spindles are present, which are short bursts of electrical activity in the brain that last for about a second to two seconds and occur at a frequency of 12 to 15 hertz. Understanding the different stages of sleep and their characteristics can help individuals develop effective sleep hygiene practices and improve their overall sleep quality.

    • Deep Sleep: Unity in the BrainDuring deep sleep, the brain exhibits synchronized electrical activity resulting in large, distinct waves, crucial for memory consolidation and physical recovery.

      During deep sleep, the brain exhibits large, slow waves of electrical activity that are much more powerful than when we are awake. These waves, known as deep slow wave sleep, are produced when large groups of neurons in the cortex synchronize their firing and go silent together. This synchronized activity results in waves that are much larger in amplitude than during wakefulness. The analogy given is that of a football stadium, where during wakefulness, the crowd is having various conversations, but during deep sleep, the entire stadium unites and speaks with one voice. These deep slow wave sleep stages are crucial for various functions including memory consolidation and physical recovery. The brainwave activity during these stages is quite distinct from that of wakefulness and is a unique feature of sleep.

    • Deep Sleep: Restoring the Body and Boosting ImmunityDeep sleep plays a vital role in calming the nervous system, restoring the immune system, regulating metabolic functions, and ensuring efficient blood sugar control for optimal health and well-being.

      Deep sleep plays a crucial role in various functions of the body and brain. During deep sleep, the body shifts into a parasympathetic state, leading to a calmer nervous system, reduced cardiovascular activity, and immune system restoration. Deep sleep also aids in regulating metabolic functions, specifically blood sugar control. By instigating the restocking of immune cells and increasing sensitivity to immune signals, deep sleep enhances the immune response. Additionally, deep sleep's impact on metabolic functions includes the proper release and response to insulin, ensuring efficient blood sugar control. Overall, deep sleep is essential for optimal health and well-being.

    • Deep sleep's role in brain health and Alzheimer's protectionDeep sleep is vital for brain health, including learning, memory, and Alzheimer's protection. REM sleep and stages 1 and 2 are also important, but their effects on health are less studied.

      Deep sleep plays a crucial role in brain health, particularly in regulating learning and memory functions, and protecting against Alzheimer's disease by washing away toxic proteins like beta amyloid and tau protein. However, it's essential to note that REM sleep also plays a significant role in the sleep cycle, and stages 1 and 2 of sleep should not be overlooked, as they are the transition into deeper sleep stages. During these stages, the body exhibits slow rolling eye movements and experiences hypnagogic jerks, which are the beginning of dreaming. While the effects of selectively depriving individuals of stages 1 and 2 sleep are not well-studied, it is known that it's challenging to isolate these stages, making it difficult to conduct such experiments. Overall, optimizing sleep quality and ensuring adequate time spent in all stages of sleep is essential for overall health and well-being.

    • Loss of proprioception during sleep causes strange experiencesThe loss of proprioception during sleep can result in the sensation of falling and the phenomenon of hypnagogic jerks, as well as contribute to the vividness of dreams during REM sleep.

      As we transition into sleep, we lose certain sensory perceptions, specifically proprioception, which is our sense of body position in space. This loss of proprioception can occur before or after we lose consciousness, and when it happens before, our brain may interpret it as falling, leading to the sensation of "jerking" or "hypnagogic jerks." During REM sleep, our brains also paralyze our bodies to prevent us from physically acting out our dreams. This loss and then regain of proprioception, along with other factors, may contribute to the strange and vivid experiences we have during the hypnagogic state and in our dreams.

    • The Paradox of REM Sleep: Paralyzed Muscles and Active BrainDuring REM sleep, muscles are paralyzed to ensure safe dreaming, while the brain remains highly active. This paradoxical state allows for intense brain activity without the risk of acting out dreams and potentially harming oneself.

      During REM sleep, your muscles are paralyzed to ensure safe dreaming, while your brain remains highly active. This paradoxical state allows for intense brain activity without the risk of acting out dreams and potentially harming oneself. The absence of muscle tone during REM sleep is what defines it from wakefulness, and the reasons for the exceptions, such as the extraoccular muscles and the muscle in the middle inner ear, are still a mystery. The sensation of falling asleep may be related to the progressive loss of proprioception, or the awareness of the position and movement of your body, in the early stages of sleep. Additionally, the way we describe falling asleep, such as "drifting off" or "falling into sleep," may be influenced by this feeling of falling. The experience of sleep can vary depending on the position, with horizontal sleeping leading to a different experience compared to sleeping upright.

    • The angle of your feet and temperature during sleep affect sleep qualityMaintaining a cool environment and sleeping on your side can improve sleep quality and help regulate temperature and breathing

      The position and orientation of the body during sleep, specifically the angle of the feet relative to the head and the temperature of the environment, can significantly impact the quality and pattern of sleep stages. The body's ability to regulate temperature and dissipate heat is superior when lying down, making it easier to fall asleep and maintain good sleep quality. Additionally, individuals with snoring or sleep apnea are more likely to experience breathing issues when sleeping on their backs, making it important for them to avoid this position. The distribution of blood flow and core body temperature play a role in these effects.

    • New discoveries about deep sleep and yawningAnimal research suggests that turning the head during deep sleep enhances brain cleansing, but this is not proven in humans. Yawning is contagious and triggered by mirror neurons in the brain, indicating a potential social function.

      During deep sleep, the brain's cleansing system becomes more effective when the head is turned to the side, according to some animal research. However, this finding is not definitively proven in humans and should not be considered a prescriptive recommendation. Another interesting discovery is that yawning is not solely a sign of tiredness, but also a contagious behavior triggered by the mirror neuron system in the brain. This theory is supported by the fact that yawning is contagious and can be observed in response to seeing others yawn. The exact function of yawning remains a topic of ongoing research.

    • The Complex Function of YawningYawning may be a complex behavior with functions for empathy, brain cooling, and sleep promotion

      Yawning is a complex behavior with several theories explaining its function. While some believe it's a contagious behavior for empathy and social bonding, others suggest it's a response to brain temperature getting too warm. The brain cooling theory proposes that yawning helps lower brain temperature, making it easier to fall asleep. However, the paradox remains that falling asleep requires a drop in core body temperature, which is achieved by warming up the outer surface of the body and brain. This process, in turn, can make people feel sleepier in a warm environment. So, while the exact reason for yawning remains unclear, it's likely a combination of various functions.

    • Understanding the Postprandial Dip and Its Effect on Afternoon EnergyThe postprandial dip is a natural decrease in brain alertness and increase in sleepiness that occurs between 1-4 p.m., not solely due to post-meal feelings. Optimizing sleep and wakefulness throughout the day is crucial for overall well-being.

      The afternoon dip in energy and increased desire to nap is not solely due to a post-meal feeling, but rather a genetically hardwired drop in brain alertness called the postprandial dip. This dip, which typically occurs between 1-4 p.m., can be measured by a decrease in brain activity and an increase in warmth, leading to a strong desire to sleep. Understanding this phenomenon can help us recognize the importance of optimizing our sleep and wakefulness throughout the day. Additionally, InsideTracker is a valuable resource for analyzing and improving various health factors, including sleep quality. By understanding the importance and functions of sleep, we can appreciate the significance of this seemingly wasteful state and take steps to ensure we're getting the best possible sleep for our overall well-being.

    • The Importance of Sufficient and Good Quality Sleep for Overall HealthSleep impacts reproductive health, metabolism, and immune system function, making sufficient and good quality sleep essential for optimal health

      Sleep is a non-negotiable life support system that has evolved with life itself. Lack of sufficient sleep can have a significant impact on various systems in the body. For instance, it can lead to hormonal imbalances, affecting both testosterone and estrogen levels, and impairing reproductive health. Additionally, a lack of sleep can disrupt the metabolic system, leading to impaired insulin function and potential prediabetes. Furthermore, one night of poor sleep can result in a 70% reduction in the activity of natural killer cells, which are crucial for the immune system's ability to fight against unwanted elements like cancer. Therefore, getting sufficient and good quality sleep is essential for maintaining optimal health.

    • Sleep's Impact on Health: From Immune System to GenesLack of sleep before a flu shot can make it less effective, chronic sleep deprivation increases cold/flu risk, sleep impacts heart health, disrupts genes, and affects emotional states of federal judges.

      Sleep plays a crucial role in various aspects of our health. Lack of sufficient sleep before getting a flu shot can make it less effective, and chronic sleep deprivation increases the risk of developing the common cold or flu by almost three times. Sleep also impacts the cardiovascular system, with studies showing a 24% relative increase in heart attack risk the day after losing an hour of sleep. Furthermore, sleep affects our genes, with one study finding that limiting sleep to six hours for a week distorted the activity of 711 genes, including those associated with the immune system, tumor promotion, chronic inflammation, and cellular stress. Sleep deprivation can even impact the emotional and mood states of federal judges, leading to harsher sentencing. In essence, sleep affects every aspect of our wellness, from our immune system to our cardiovascular health and even our genes. It's essential to prioritize getting enough sleep to maintain optimal health.

    • The Importance of Sleep for Learning and MemorySleep enhances learning by preparing the brain to absorb new information and consolidates memories, improving recall and reducing forgetting.

      Sleep is essential for optimal learning and memory retention. Matt Walker, a sleep scientist, emphasized that both before and after learning, sleep plays a crucial role. During sleep, the brain's learning centers are more prepared to absorb new information, making it easier to learn and retain. After learning, sleep consolidates and connects new memories, making them more likely to be remembered and less likely to be forgotten. So, instead of focusing solely on the negative consequences of sleep deprivation, it's important to recognize the benefits of getting a good night's sleep for learning and memory.

    • Sleep enhances learning and memory by building associative networksSleep improves memory by linking related information and boosts mood while maintaining hormonal balance for appetite regulation.

      Sleep plays a crucial role in enhancing our learning and memory by building associative networks in the brain. It goes beyond just storing facts and turns them into meaningful knowledge by linking related information. Sleep also acts as an emotional balm, improving mood and clearing emotional wounds. Additionally, it significantly impacts appetite regulation and weight gain by maintaining a balance of hormones that signal satiety and hunger. Overall, sleep's benefits extend to almost every aspect of brain and body health, making it essential for optimal functioning.

    • Sleep Deprivation Affects Food CravingsSleep deprivation increases hunger hormones and decreases fullness hormones, leading to cravings for unhealthy foods and weight gain.

      Lack of sleep not only makes you feel hungry and increases your appetite, but it also affects the types of foods you crave. When you're sleep-deprived, your body produces more ghrelin, a hormone that stimulates hunger, and less leptin, a hormone that signals fullness. This double whammy can lead to weight gain, especially from "obesogenic" foods like heavy carbohydrates and simple sugars. Furthermore, sleep deprivation increases the production of endocannabinoids, which are appetite-stimulating chemicals in the brain. These hormonal changes can make it difficult to make healthy food choices and lead to unhealthy eating patterns. Additionally, lack of sleep affects the brain regions responsible for regulating emotions and making healthy decisions, making it even harder to resist unhealthy foods. In summary, getting sufficient sleep is crucial for maintaining a healthy weight and making good food choices.

    • The Importance of Sleep for Emotions, Mood, and Body WeightSleeping for 8 hours helps reset health functions, improves mood, and maintains a healthy immune system and appearance

      Getting good sleep is essential for regulating emotions and improving mood and body weight. According to a study by Michael Grandner, people want to improve their sleep for these reasons. Sleep deprivation can be quickly noticed in a person's skin and eyes, and the immune system is affected, leading to a sickly look and bags under the eyes. After about 16 hours of wakefulness, the body needs about eight hours of sleep to reset various health and physiology functions. The study by Tina Sunderland further highlights the importance of sleep in maintaining a healthy immune system and appearance. Overall, the carrots for improving sleep include better mood and improved body weight.

    • Understanding the 'macros' of sleep: Quantity, Quality, Regularity, and TimingImprove sleep quality, regularity, and timing, not just quantity, for optimal rest. Focus on these 'macros' using the acronym QQRT.

      Sleep is not just about the number of hours spent sleeping, but also about the quality, regularity, and timing. These four aspects, known as the "macros of sleep," are essential for optimal sleep. The study discussed in the text demonstrated the importance of quantity, as sleep-deprived individuals were perceived as less attractive and more tired. However, sleep quality is equally important, with continuous sleep leading to better overall sleep efficiency. Regularity refers to maintaining consistent sleep patterns, while timing relates to the alignment of sleep with the body's natural circadian rhythm. Remembering the acronym QQRT (Quantity, Quality, Regularity, and Timing) can help you focus on these aspects to improve your sleep experience.

    • Measuring sleep quality beyond hours sleptStrive for adequate quantity, high-quality deep sleep, and regular sleep patterns to optimize overall health.

      While the quantity of sleep is important, it's not the only factor that determines the quality of your rest. Sleep efficiency, or the percentage of time spent asleep during your total time in bed, is another crucial measure of sleep quality. Additionally, the deep sleep stage's electrical quality also plays a role in determining the restorative power of your sleep. Regularity, or maintaining consistent sleep patterns, has also emerged as a significant factor in recent years. It's essential to strive for both adequate quantity and high-quality sleep, as well as regular sleep patterns, to optimize overall health.

    • Consistent sleep patterns linked to lower mortality riskRegular sleep schedule reduces mortality risk by 49% due to decreased cancer and cardiovascular mortality, and regularity carries a bigger impact than duration.

      The consistency and timing of our sleep plays a significant role in our overall health and mortality risk. A study using the UK Biobank database found that individuals with regular sleep patterns had a 49% reduced risk of mortality compared to those with irregular sleep. This reduction in risk was due to a 35% decrease in cancer mortality and almost a 60% decrease in cardiovascular mortality. The study also found that regularity carried almost twice the effect size of the duration of sleep. Therefore, aiming for a consistent sleep schedule and understanding your chronotype (morning, evening, or in between) can lead to better health outcomes.

    • Understanding your chronotype for optimal sleepDetermining your chronotype through a quiz or self-reflection can help optimize sleep and feel more energized, recognizing the benefits of all types and avoiding stigmatization.

      Our sleep patterns change as we grow older, and once we reach adulthood, we have a stable rhythm in place. However, there is variability, and sleep science categorizes this into five types: extreme morning, morning, neutral, evening, and extreme evening. For instance, an extreme morning type might go to bed at 8 pm and wake up at 4:30 am, while a neutral type like myself goes to bed around 11 pm and wakes up around 7:30 am. Understanding your chronotype can help you optimize your sleep and feel more energized throughout the day. To determine your chronotype, you can take an online quiz called the Chronotype MEQ, or answer the question of what time your body would like to go to sleep and wake up if you were alone on a desert island with no responsibilities. It's essential to remember that society often favors morning types, but evening types have their unique benefits and should not be stigmatized.

    • Understanding Chronotypes: Genetics and Natural Sleep PatternsRecognize and respect the diversity of chronotypes, as genetics largely determine our natural sleep patterns and work towards creating more flexible and inclusive workplaces.

      Our chronotype, or natural sleep pattern, is largely determined by genetics and not a matter of personal choice or work ethic. This means that morning types, who are more active during the day and tired in the evening, and evening types, who are more active at night and tired during the day, both have valid and natural sleep patterns. However, societal stigma and expectations can make it challenging for evening types to thrive in work environments that prioritize early hours. Additionally, disrupting our natural sleep patterns can lead to sleep deprivation and negative health consequences. It's essential to recognize and respect the diversity of chronotypes and work towards creating more flexible and inclusive workplaces that accommodate the needs of all individuals.

    • Understanding Chronotypes for Optimal SleepAligning sleep with individual chronotypes can improve sleep quality and overall health. Misalignment can lead to sleep disorders and other health issues.

      The quality and effectiveness of sleep can depend on aligning it with our individual chronotypes – our natural tendencies toward morning or evening. Those who are evening types may have difficulty falling asleep if they go to bed too early, while those who are morning types may struggle to stay asleep if they go to bed too late. Misaligning our sleep with our chronotype can lead to sleep disorders and other health issues. Therefore, it's crucial to understand our chronotype and adjust our sleep schedule accordingly. The concept of chronotypes provides insight into why shift work, which requires working against our natural rhythms, can lead to health problems. Ultimately, sleep quality is not just about quantity, but also about timing and regularity.

    • Checking for adequate sleepAssess your alertness, concentration, and response to alarm clock to determine if you're getting enough sleep. Listen to your body and aim for restoration.

      Getting enough quality sleep is crucial for our health and well-being, and there are simple tests to determine if we're getting enough. The first test is to check if we would sleep past our alarm clock if it didn't go off. If the answer is yes, we may not be getting enough sleep. Animals, on the other hand, would never do this. Another test is to assess our level of alertness and concentration. When we're under-slept, we may have lapses of attention, which can be measured through concentration tests. These lapses are caused by micro-sleeps, where the brain briefly enters a sleep-like state. Lastly, we should listen to our bodies and assess if we feel restored after a night's sleep. If not, we may need to adjust our sleep habits. It's important to remember that we may not always be aware of the negative effects of sleep deprivation, so it's essential to prioritize getting enough quality sleep for our overall health.

    • Evaluating Sleep Quality: Beyond Refreshed FeelingsSleep quality involves more than just feeling refreshed upon waking. Consider factors like sleep inertia, post-lunch energy dips, and excessive daytime sleepiness to assess overall sleep health.

      The quality and quantity of sleep are crucial for good mood, cognition, and energy levels. However, feeling refreshed and restored after a night's sleep is not the only metric to evaluate sleep quality. Some people may experience sleep inertia, a period of grogginess after waking up that can last up to an hour. Additionally, a post-lunch energy dip is a natural part of the circadian rhythm for many people and should not necessarily be a cause for concern. However, excessive daytime sleepiness throughout the day could indicate a sleep disorder, and it's essential to pay attention to energy levels around 11 a.m., as most people have reached their peak by that time. Overall, it's essential to consider various factors when evaluating sleep quality and to consult a healthcare professional if concerns persist.

    • Internal circadian rhythm and sleep pressure determine wakefulness and sleepinessOur bodies are regulated by an internal clock and sleep pressure, influencing our desire to be awake or asleep, and optimal performance hours based on individual chronotypes.

      Our wakefulness and sleepiness are determined by two main forces: our internal circadian rhythm and sleep pressure. Our circadian rhythm, regulated by the suprachiasmatic nucleus in our brain, influences our desire to be awake during the day and asleep at night. However, after being awake for approximately 16 hours, a chemical called adenosine builds up in our brains, leading to sleep pressure and the feeling of tiredness. Together, these two forces work to regulate our sleep-wake cycle. Additionally, our peak performance and optimal work output are linked to our circadian rhythm, suggesting that our bodies function best during certain hours based on our individual chronotypes.

    • Understanding Sleep and Circadian RhythmOur circadian rhythm and sleep pressure work together to regulate our sleep-wake cycle. Circadian rhythm follows a 24-hour cycle, while sleep pressure builds up as we stay awake. Both are independent processes, but sleep pressure can influence our circadian rhythm when we're sleep-deprived.

      Our circadian rhythm and sleep pressure are two independent biological processes that work together to regulate our sleep-wake cycle. While our circadian rhythm follows a 24-hour cycle, sleep pressure builds up as we stay awake, peaking when we're most tired. Normally, these two processes align, with sleep pressure determining when we feel most sleepy and our circadian rhythm guiding our natural wake-up time. However, if we're deprived of sleep, our circadian rhythm can help alleviate the excessive sleepiness by starting its upward swing, making us feel more alert. Adenosine, the chemical responsible for sleep pressure, builds up in the brain and body, making us feel sleepier as it rises. It does this by decreasing the activity of wake-promoting regions in the brain. Despite their interdependence, both processes function independently, with one having no influence on the other.

    • Clearing metabolic waste during sleep for optimal brain functionSleep helps clear waste and release growth hormone for optimal brain function and overall health

      During sleep, particularly deep non-REM sleep, the body is able to clear away metabolic waste, such as adenosine, which builds up during wakefulness and promotes feelings of sleepiness. This process is important for maintaining optimal brain function and overall health. Additionally, growth hormone, which is crucial for growth and tissue repair, is primarily released during sleep, highlighting the importance of consistent and adequate sleep for overall well-being. The timing and quality of sleep also play a role in the effectiveness of this restorative process.

    • Sleep's role in growth hormone release and cortisol regulationGetting enough and good quality sleep is vital for growth hormone release and cortisol regulation, ensuring optimal health and well-being. Deep sleep specifically helps reduce stress response and cortisol release.

      Sleep plays a crucial role in the release of growth hormone and the regulation of cortisol. While growth hormone can be released during non-natural hours due to sleep, the quality and quantity of sleep, especially deep sleep, significantly impact its release. On the other hand, cortisol, often seen as a bad hormone, is essential for immune system function, waking, and memory formation. During sleep, the body naturally keeps cortisol at bay, allowing for restorative processes. Deep sleep contributes to this by reducing the stress response and the release of cortisol. Cortisol also follows a circadian rhythm, with levels dropping during the night, making it important to avoid stressors and disturbing news in the late evening to maintain optimal sleep quality and prevent cortisol from impeding the sleep structure. In summary, getting sufficient and good quality sleep is essential for growth hormone release and cortisol regulation, contributing to overall health and well-being.

    • Understanding the importance of sleep and its impact on health and performancePrioritize good sleep hygiene by focusing on quantity, quality, regularity, and timing as the four macronutrients of good sleep. Sleep impacts mental and physical health, and poor sleep can lead to negative consequences. Improve and optimize sleep through research and resources.

      Sleep is a crucial aspect of our overall health and well-being, and it's essential to prioritize good sleep hygiene. The different sleep cycles and their interrelationships were discussed, along with the importance of quantity, quality, regularity, and timing as the four macronutrients of good sleep. Sleep impacts mental health, physical health, and performance, and the consequences of good and bad sleep were explored. A huge thank you to Dr. Matthew Walker for shedding light on this topic and for his advocacy for science and health. To improve and optimize sleep, we look forward to the next episode in this mini-series. For more information on Dr. Walker's research and resources, check out the links in the show notes. Don't forget to subscribe to the podcast and leave a review, and follow Huberman Lab on social media for science-related content. Additionally, consider checking out the supplements discussed on the Huberman Lab podcast for sleep and other health benefits. Subscribe to the neural network newsletter for zero-cost podcast summaries and protocols on various topics. And lastly, a big thank you for your interest in science.

    Recent Episodes from Huberman Lab

    Dr. Gabrielle Lyon: How to Exercise & Eat for Optimal Health & Longevity

    Dr. Gabrielle Lyon: How to Exercise & Eat for Optimal Health & Longevity
    In this episode, my guest is Dr. Gabrielle Lyon, D.O., a board-certified physician who did her clinical and research training at Washington University in geriatrics and nutrition. She is also an expert in how diet and exercise impact muscle and whole-body health and longevity. Dr. Lyon is a bestselling author and public educator. We discuss how healthy skeletal muscle promotes longevity, brain health, disease prevention, ideal body composition, and the health of other organs and bodily systems. She makes specific nutritional recommendations for optimal health: what to eat, how much to eat, the timing of meals, the essential need for adequate quality protein (including animal and plant-based options), supplementation, and how our dietary requirements change with age. She explains why specific types of resistance training are essential to build and maintain muscle and overall metabolic health. She also describes how to include resistance training as part of your exercise regimen — regardless of age or sex.  She also provides specific mindset tools to encourage sustained adherence to healthy eating and exercise practices. Women and men of all ages will benefit from Dr. Lyon’s practical, evidence-based protocols to improve muscle and whole-body appearance, function, and health. Access the full show notes, including referenced articles, books, people mentioned, and additional resources at hubermanlab.com. Andrew's New Book Protocols: An Operating Manual for the Human Body: https://protocolsbook.com Thank you to our sponsors AG1: https://drinkag1.com/huberman Maui Nui Venison: https://mauinuivenison.com/huberman  Levels: https://levels.link/huberman  Helix Sleep: https://helixsleep.com/huberman InsideTracker: https://insidetracker.com/huberman  Timestamps 00:00:00 Protocols Book; Dr. Gabrielle Lyon 00:03:23 Sponsors: Maui Nui, Levels & Helix Sleep 00:07:40 Skeletal Muscle & Longevity 00:11:25 “Under-muscled”, Leucine & Muscle Health 00:15:55 Muscle Health 00:19:45 Tool: Carbohydrate Consumption & Activity, Glycogen 00:25:14 Tools: Nutrition for Healthy Skeletal Muscle, First Meal 00:31:57 Sponsor: AG1 00:33:46 Quality Protein, Animal & Plant-Based Proteins 00:37:36 Dietary Protein Recommendations, Meal Threshold 00:41:19 Muscle Health & Aging 00:46:02 Supplements & Creatine; Dietary Protein 00:50:07 Tool: Dietary Protein Recommendation; Gout & Cancer Risk 00:52:43 Effects of Dietary Protein & Exercise on Body Composition 01:03:06 Thermic Effects, Protein  01:05:02 Sponsor: InsideTracker 01:06:14 Protein & Satiety, Insulin & Glucose 01:12:04 Tool: Older Adults, Resistance Training & Dietary Protein 01:17:48 Dietary Protein, mTOR & Cancer Risk 01:21:36 Muscle Span & Aging, Sedentary Behaviors 01:24:00 Mixed Meals, Protein Quality, Fiber 01:29:21 Inactivity & Insulin Resistance, Inflammation 01:38:43 Exercise & Myokines, Brain Health & BDNF 01:44:11 Tool: Resistance Training Protocols, Hypertrophy, “High Ground” 01:52:51 High Ground Exercises; Tendon Strength; Training Duration, Blue Zones 01:58:19 Movement, Exercise & Older Adults 02:04:25 Tool: Protein Timing & Resistance Training; VO2 Max, Aging, Blood Work 02:11:13 Supplements: Creatine, Urolithin A, Whey Protein, Fish Oil, Collagen 02:20:18 Fasting, Older Adults; Tool: Meal Timing 02:25:18 Animal Proteins & Dairy; Organ Meats, Vegan; Magnesium, Zinc 02:30:59 Medications & Muscle Health 02:32:49 Obesity & GLP-1 Analogs, Ozempic, Mounjaro, Skeletal Muscle 02:40:48 Benefits of Skeletal Muscle & Aging 02:42:16 Tools: Nutrition & Resistance Training for Muscle Health 02:45:44 Mindset Tools: Standards vs. Goals; Vulnerability Points 02:52:00 Mindset Tools: Neutrality; Health & Worth 03:01:14 Zero-Cost Support, Spotify & Apple Follow & Reviews, YouTube Feedback, Social Media, Neural Network Newsletter, Protocols Book Disclaimer
    Huberman Lab
    enJune 24, 2024

    Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It

    Perform with Dr. Andy Galpin: Why Muscle Matters & How to Build It
    I'm honored to share Episode 2 of the first season of Perform with Dr. Andy Galpin. Dr. Andy Galpin is a tenured full professor at California State University, Fullerton, where he co-directs the Center for Sport Performance and leads the Biochemistry and Molecular Exercise Physiology Laboratory. Andy is both a friend and a colleague, and I'm delighted to have assisted in the creation of this podcast. I'm certain you'll both enjoy and learn from it. Season 1 features 10 episodes, airing every Wednesday for 10 weeks. Dr. Galpin will cover everything from building strength, the importance of strength for long-term health, the science of breathing, the benefits of sleep extension, genetic testing for personalized training, and nutrition for injury recovery. While we have Episode 2 of Perform with Dr. Andy Galpin here, please be sure to subscribe and follow Perform with Dr. Andy Galpin on your preferred platform. Show notes for this episode can be found at performpodcast.com. Timestamps 00:00:00 Introduction from Dr. Andrew Huberman 00:01:06 Skeletal Muscle 00:04:06 Sponsors: Absolute Rest & Momentous 00:07:20 Quantity & Quality; Organ System; Health & Performance 00:12:58 Plasticity, “Look Good, Feel Good, Play Good”; Muscle Types 00:15:46 What is Muscle?, Muscle Fibers, Tendon 00:21:37 Muscle Fiber Number, Hyperplasia, Anabolic Steroids, Age 00:24:03 Myonuclei & Adaptability 00:26:27 Muscle Fiber Types, Variable Muscle Functions 00:32:24 Fiber Type & Lifestyle Factors 00:34:54 Sponsors: David Protein & AG1 00:37:37 Age & Muscle Loss, Slow vs. Fast-Twitch Fibers; Motor Units 00:46:36 Muscle Size vs. Muscle Strength, Quantity vs. Quality 00:50:56 Investigate: Muscle Quantity, Fat-Free Mass Index (FFMI) 00:56:21 FFMI, Elite Athletes, Muscle Mass 01:00:59 Muscle Asymmetry; Too Much Muscle Possible? 01:03:49 Interpret: Muscle Mass, FFMI Calculations & Percentiles 01:09:28 Tool: Intervene - Increase Muscle Mass, 72-Hour Rule 01:15:27 Sponsors: Maui Nui & Renaissance Periodization 01:17:51 Investigate: Muscle Quality & 4 Movement Principles 01:23:34 Muscle Quality & 3 Performance Principles  01:26:42 Interpret: Muscle Speed, Age 01:32:45 Muscle Power, Vertical Jump, Broad Jump 01:36:17 Muscle Strength, Powerlifting Elite, Bench Press, Leg Press, Grip Strength 01:44:05 Increasing Strength, Improve Health & Longevity 01:46:44 Tool: Intervene - Improve Muscle Quality, 4 Training Principles, 3-to-5 Rule 01:53:56 Zero-Cost Support, YouTube, Spotify & Apple Subscribe & Reviews, Sponsors, YouTube Feedback, Social Media 01:56:10 Conclusion from Dr. Andrew Huberman Disclaimer
    Huberman Lab
    enJune 19, 2024

    Dr. Zachary Knight: The Science of Hunger & Medications to Combat Obesity

    Dr. Zachary Knight: The Science of Hunger & Medications to Combat Obesity
    In this episode, my guest is Dr. Zachary Knight, Ph.D., a professor of physiology at the University of California, San Francisco (UCSF), and Howard Hughes Medical Institute (HHMI) investigator. We discuss how the brain controls our sense of hunger, satiety, and thirst. He explains how dopamine levels impact our cravings and eating behavior (amount, food choices, etc) and how we develop and can change our food preferences and adjust how much we need to eat to feel satisfied. We discuss factors that have led to the recent rise in obesity, such as interactions between our genes and the environment and the role of processed foods and food combinations. We also discuss the new class of medications developed for the treatment of obesity and diabetes, including the GLP-1 agonists semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro). We discuss how these medications work to promote weight loss, the source of their side effects, and the newer compounds soon to overcome some of those side effects, such as muscle loss. Dr. Knight provides an exceptionally clear explanation for our sense of hunger, thirst, and food cravings that translates to practical knowledge to help listeners better understand their relationship to food, food choices, and meal size to improve their diet and overall health. For show notes, including referenced articles and additional resources, please visit hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman  BetterHelp: https://betterhelp.com/huberman Eight Sleep: https://eightsleep.com/huberman Waking Up: https://wakingup.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Dr. Zachary Knight 00:02:38 Sponsors: BetterHelp, Helix Sleep & Waking Up 00:07:07 Hunger & Timescales 00:11:28 Body Fat, Leptin, Hunger 00:17:51 Leptin Resistance & Obesity 00:20:52 Hunger, Food Foraging & Feeding Behaviors, AgRP Neurons 00:30:26 Sponsor: AG1 00:32:15 Body Weight & Obesity, Genes & POMC Neurons 00:39:54 Obesity, Genetics & Environmental Factors 00:46:05 Whole Foods, Ultra-Processed Foods & Palatability 00:49:32 Increasing Whole Food Consumption, Sensory Specific Satiety & Learning 00:58:55 Calories vs. Macronutrients, Protein & Salt 01:02:23 Sponsor: LMNT 01:03:58 Challenges of Weight Loss: Hunger & Energy Expenditure 01:09:50 GLP-1 Drug Development, Semaglutide, Ozempic, Wegovy 01:19:03 GLP-1 Drugs: Muscle Loss, Appetite Reduction, Nausea 01:23:24 Pharmacologic & Physiologic Effects; GLP-1 Drugs, Additional Positive Effects 01:30:14 GLP-1-Plus Development, Tirzepatide, Mounjaro, AMG 133 01:34:49 Alpha-MSH & Pharmacology 01:40:41 Dopamine, Eating & Context 01:46:01 Dopamine & Learning, Water Content & Food 01:53:23 Salt, Water & Thirst 02:03:27 Hunger vs. Thirst 02:05:46 Dieting, Nutrition & Mindset 02:09:39 Tools: Improving Diet & Limiting Food Intake 02:14:15 Anti-Obesity Drug Development 02:17:03 Zero-Cost Support, Spotify & Apple Follow & Reviews, YouTube Feedback, Social Media, Neural Network Newsletter Disclaimer
    Huberman Lab
    enJune 17, 2024

    Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness

    Perform with Dr. Andy Galpin: How & Why to Strengthen Your Heart & Cardiovascular Fitness
    I'm honored to share the first episode of the new podcast, Perform with Dr. Andy Galpin. Dr. Andy Galpin is a tenured full professor at California State University, Fullerton, where he co-directs the Center for Sport Performance and leads the Biochemistry and Molecular Exercise Physiology Laboratory. Andy is both a friend and a colleague, and I’m delighted to have assisted in the creation of this podcast. I'm certain you'll both enjoy and learn from it. Season 1 features 10 episodes, airing every Wednesday for 10 weeks. Dr. Galpin will cover everything from building strength, the importance of strength for long-term health, the science of breathing, the benefits of sleep extension, genetic testing for personalized training, and nutrition for injury recovery. While we have Episode 1 of Perform with Dr. Andy Galpin here, please be sure to subscribe and follow Perform with Dr. Andy Galpin on your preferred platform. Show notes for this episode can be found at performpodcast.com. Timestamps 00:00:00 Introduction from Dr. Andrew Huberman 00:01:07 Heart 00:03:55 Sponsors: Vitality Blueprint & Rhone 00:07:27 Muscle Types 00:09:54 VO2 max, Health & Mortality 00:15:49 Overall Health, Cardiorespiratory Fitness & All-Cause Mortality 00:25:23 Sponsor: AG1 00:26:54 Disease, Health & Mortality 00:30:02 Cardiac Muscle & Heart 00:38:29 Cardiac Muscle vs. Skeletal Muscle, Cardiac Advantages 00:43:53 Pacemakers & Heart Rate, Vagus Nerve 00:50:35 Why Doesn’t the Heart Get Sore? 00:54:32 Heart & Exercise, Stroke Volume, Ejection Fraction, Cardiac Output 00:59:21 Heart Rate Variability 01:02:41 Sponsors: Momentous & LMNT 01:06:54 Why Do You Breathe?: Oxygen, Carbon Dioxide & Respiratory Rate 01:13:37 Respiratory Rate & Stress 01:15:08 Tool: The “Three I’s”, Investigate: Heart Rate, Respiratory Rate, VO2 Max 01:19:53 Tool: Interpretation, Resting Heart Rate & Ranges 01:23:16 Tool: Interpretation: VO2 Max & Ranges 01:30:45 Athletes & Highest VO2 Max Scores 01:35:53 Elite Athletes & Context for VO2 Max Scores 01:41:42 Tool: Intervention, VO2 Max, Varying Exercise Intensities, SAID Principle 01:48:20 Tool: Varying Exercise Intensity; Intervals & Continuous Training; Frequency 01:58:18 Zero-Cost Support, YouTube, Spotify & Apple Subscribe & Reviews, Sponsors, YouTube Feedback, Social Media 01:59:55 Conclusion from Dr. Andrew Huberman Disclaimer
    Huberman Lab
    enJune 12, 2024

    Dr. Jonathan Haidt: How Smartphones & Social Media Impact Mental Health & the Realistic Solutions

    Dr. Jonathan Haidt: How Smartphones & Social Media Impact Mental Health & the Realistic Solutions
    In this episode, my guest is Dr. Jonathan Haidt, Ph.D., professor of social psychology at New York University and bestselling author on how technology and culture impact the psychology and health of kids, teens, and adults. We discuss the dramatic rise of suicide, depression, and anxiety as a result of replacing a play-based childhood with smartphones, social media, and video games. He explains how a screen-filled childhood leads to challenges in psychological development that negatively impact learning, resilience, identity, cooperation, and conflict resolution — all of which are crucial skills for future adult relationships and career success. We also discuss how phones and social media impact boys and girls differently and the underlying neurobiological mechanisms of how smartphones alter basic brain plasticity and function.  Dr. Haidt explains his four recommendations for healthier smartphone use in kids, and we discuss how to restore childhood independence and play in the current generation.  This is an important topic for everyone, young or old, parents and teachers, students and families, to be aware of in order to understand the potential mental health toll of smartphone use and to apply tools to foster skill-building and reestablish healthy norms for our kids. For show notes, including referenced articles and additional resources, please visit hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman  Helix Sleep: https://helixsleep.com/huberman AeroPress: https://aeropress.com/huberman Joovv: https://joovv.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Dr. Jonathan Haidt 00:02:01 Sponsors: Helix Sleep, AeroPress & Joovv 00:06:23 Great Rewiring of Childhood: Technology, Smartphones & Social Media 00:12:48 Mental Health Trends: Boys, Girls & Smartphones 00:16:26 Smartphone Usage, Play-Based to Phone-Based Childhood 00:20:40 The Tragedy of Losing Play-Based Childhood 00:28:13 Sponsor: AG1 00:30:02 Girls vs. Boys, Interests & Trapping Kids 00:37:31 “Effectance,” Systems & Relationships, Animals 00:41:47 Boys Sexual Development, Dopamine Reinforcement & Pornography 00:49:19 Boys, Courtship, Chivalry & Technology; Gen Z Development 00:55:24 Play & Low-Stakes Mistakes, Video Games & Social Media, Conflict Resolution 00:59:48 Sponsor: LMNT 01:01:23 Social Media, Trolls, Performance 01:06:47 Dynamic Subordination, Hierarchy, Boys 01:10:15 Girls & Perfectionism, Social Media & Performance 01:14:00 Phone-Based Childhood & Brain Development, Critical Periods 01:21:15 Puberty & Sensitive Periods, Culture & Identity 01:23:55 Brain Development & Puberty; Identity; Social Media, Learning & Reward 01:33:37 Tool: 4 Recommendations for Smartphone Use in Kids 01:41:48 Changing Childhood Norms, Policies & Legislature 01:49:13 Summer Camp, Team Sports, Religion, Music 01:54:36 Boredom, Addiction & Smartphones; Tool: “Awe Walks” 02:03:14 Casino Analogy & Ceding Childhood; Social Media Content 02:09:33 Adult Behavior; Tool: Meals & Phones 02:11:45 Regaining Childhood Independence; Tool: Family Groups & Phones 02:16:09 Screens & Future Optimism, Collective Action, KOSA Bill 02:24:52 Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Social Media, Neural Network Newsletter Disclaimer
    Huberman Lab
    enJune 10, 2024

    LIVE EVENT Q&A: Dr. Andrew Huberman at the Brisbane Convention & Exhibition Centre

    LIVE EVENT Q&A: Dr. Andrew Huberman at the Brisbane Convention & Exhibition Centre
    Recently I had the pleasure of hosting a live event in Brisbane, Australia. This event was part of a lecture series called The Brain Body Contract. My favorite part of the evening was the question and answer period, where I had the opportunity to answer questions from the attendees of each event. Included here is the Q&A from our event at the Brisbane Convention & Exhibition Centre. Sign up to get notified about future events: https://www.hubermanlab.com/events Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Resources Mentioned Huberman Lab Non-Sleep Deep Rest Protocols Huberman Lab Guest Series with Dr. Matt Walker Huberman Lab Guest Series with Dr. Paul Conti Huberman Lab Guest Series with Dr. Andy Galpin Dr. Becky Kennedy: Protocols for Excellent Parenting & Improving Relationships of All Kinds Perform with Dr. Andy Galpin Timestamps 00:00 Introduction 00:31 Sponsors: AG1 & Eight Sleep 03:48 Nicotine Discussion 07:42 ADHD Management: Tools & Medications 12:43 Sleep Deprivation & Recovery 18:54 Understanding & Addressing Burnout 22:12 Daily Nutrition & Eating Habits 24:40 Understanding Food & Neural Pathways 26:21 The Benefits of Elimination Diets 27:21 Intermittent Fasting & Personal Diet Choices 28:23 Top Health & Fitness Recommendations 30:50 The Value of Non-Sleep Deep Rest (NSDR) 33:08 Testosterone Replacement Therapy Insights 38:02 Breathing Techniques for Stress & Focus 41:46 Morning Sunlight & Circadian Rhythms 43:18 Parenting Tips for a Healthy Start 49:03 Final Thoughts & Gratitude Disclaimer
    Huberman Lab
    enJune 07, 2024

    Dr. Mary Claire Haver: How to Navigate Menopause & Perimenopause for Maximum Health & Vitality

    Dr. Mary Claire Haver: How to Navigate Menopause & Perimenopause for Maximum Health & Vitality
    In this episode, my guest is Dr. Mary Claire Haver, M.D., a board-certified OB/GYN and an expert on women’s health and menopause. We discuss the biology and symptoms of perimenopause and menopause and their effects on body composition, cardiometabolic health, mental health, and longevity. She explains the lifestyle factors, including nutrition, resistance training, sleep, and supplements, that can better prepare women for and improve symptoms of both perimenopause and menopause. We also discuss hormone replacement therapy (HRT) and whether HRT impacts the incidence of breast cancer or can affect cardiovascular health. We also discuss contraception, cellulite, polycystic ovary syndrome (PCOS), and how to reduce the risk of osteoporosis. This episode is rich in actionable information related to what is known about menopause and perimenopause and the stages before, allowing women of all ages to best navigate these life stages. For show notes, including referenced articles and additional resources, please visit hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman  AeroPress: https://aeropress.com/huberman  Eight Sleep: https://eightsleep.com/huberman  BetterHelp: https://betterhelp.com/huberman  InsideTracker: https://insidetracker.com/huberman  Timestamps 00:00:00 Dr. Mary Claire Haver 00:02:04 Sponsors: AeroPress, Eight Sleep & BetterHelp 00:06:26 Menopause, Age of Onset 00:09:50 Perimenopause, Hormones & “Zone of Chaos” 00:14:42 Perimenopause, Estrogen & Mental Health 00:20:04 Perimenopause Symptoms; Tool: Lifestyle Factors & Ovarian Health 00:25:26 Early Menopause, Premature Ovarian Failure; Estrogen Therapy 00:29:42 Sponsor: AG1 00:31:31 Contraception, Transdermal, IUDs; Menopause Onset, Freezing Eggs 00:38:18 Women’s Health: Misconceptions & Research 00:45:01 Tool: Diet, Preparing for Peri-/Menopause; Visceral Fat 00:48:31 Tools: Body Composition, Muscle & Menopause, Protein Intake 00:51:42 Menopause: Genetics, Symptoms; Tools: Waist-to-Hip Ratio; Gut Microbiome 00:58:22 Galveston vs. Mediterranean Diet, Fasting, Tool: Building Muscle 01:05:18 Sponsor: InsideTracker 01:06:29 Hot Flashes; Estrogen Hormone Replacement Therapy (HRT), Breast Cancer Risk & Cognition 01:15:36 Estrogen HRT, Cardiovascular Disease, Blood Clotting; “Meno-posse” 01:24:00 Estrogen & Testosterone: Starting HRT & Ranges 01:30:36 Other Hormones, Thyroid & DHEA; Local Treatment, Urinary Symptoms 01:37:57 OB/GYN Medical Education & Menopause 01:41:30 Supplements, Fiber, Tools: Osteoporosis “Prevention Pack” 01:46:53 Collagen, Cellulite, Bone Density 01:51:42 HRT, Vertigo, Tinnitus, Dry Eye; Conditions Precluding HRT  01:55:27 Polycystic Ovary Syndrome (PCOS) & Treatment; GLP-1, Addictive Behaviors 02:01:55 Post-menopause & HRT, Sustained HRT Usage 02:04:58 Mental Health, Perimenopause vs. Menopause; Sleep Disruptions, Alcohol 02:09:09 Male Support; Rekindle Libido 02:12:46 HRT Rash Side-Effect; Acupuncture; Visceral Fat 02:16:24 Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Social Media, Neural Network Newsletter Disclaimer
    Huberman Lab
    enJune 03, 2024

    Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis

    Dr. Diego Bohórquez: The Science of Your Gut Sense & the Gut-Brain Axis
    In this episode, my guest is Dr. Diego Bohórquez, PhD, professor of medicine and neurobiology at Duke University and a pioneering researcher into how we use our ‘gut sense.’ He describes how your gut communicates to your brain and the rest of your body through hormones and neural connections to shape your thoughts, emotions, and behaviors. He explains how your gut senses a range of features such as temperature, pH, the macro- and micronutrients in our foods, and much more and signals that information to the brain to affect our food preferences, aversions, and cravings. Dr. Bohórquez describes his early life in the Amazon jungle and how exposure to traditional agriculture inspired his unique expertise combining nutrition, gastrointestinal physiology, and neuroscience. We discuss how the gut and brain integrate sensory cues, leading to our intuitive “gut sense” about food, people, and situations. This episode provides a scientific perspective into your gut sense to help you make better food choices and, indeed, to support better decision-making in all of life. For show notes, including referenced articles and additional resources, please visit hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Joovv: https://joovv.com/huberman LMNT: https://drinklmnt.com/huberman Helix Sleep: https://helixsleep.com/huberman InsideTracker: https://insidetracker.com/huberman Timestamps 00:00:00 Dr. Diego Bohórquez 00:02:37 Sponsors: Joovv, LMNT & Helix Sleep; YouTube, Spotify & Apple Subscribe 00:06:49 Gut-Brain Axis 00:11:35 Gut Sensing, Hormones 00:15:26 Green Fluorescent Protein; Neuropod Cells & Environment Sensing 00:26:57 Brain & Gut Connection, Experimental Tools & Rabies Virus 00:35:28 Sponsor: AG1 00:37:00 Neuropod Cells & Nutrient Sensing 00:43:55 Gastric Bypass Surgery, Cravings & Food Choice 00:51:14 Optogenetics; Sugar Preference & Neuropod Cells 01:00:29 Gut-Brain Disorders, Irritable Bowel Syndrome 01:03:03 Sponsor: InsideTracker 01:04:04 Gut & Behavior; Gastric Bypass, Cravings & Alcohol 01:07:38 GLP-1, Ozempic, Neuropod Cells 01:11:46 Food Preference & Gut-Brain Axis, Protein 01:21:35 Protein & Sugar, Agriculture & ‘Three Sisters’ 01:25:16 Childhood, Military School; Academics, Nutrition & Nervous System 01:36:15 Plant Wisdom, Agriculture, Indigenous People 01:41:48 Evolution of Food Choices; Learning from Plants 01:48:15 Plant-Based Medicines; Amazonia, Guayusa Ritual & Chonta Palm 01:56:58 Yerba Mate, Chocolate, Guayusa 02:00:22 Brain, Gut & Sensory Integration; Variability 02:06:01 Electrical Patterns in Gut & Brain, “Hangry” 02:12:43 Gut Intuition, Food & Bonding; Subconscious & Superstition 02:22:00 Vagus Nerve & Learning, Humming 02:26:46 Digestive System & Memory; Body Sensing 02:32:51 Listening to the Body, Meditation 02:40:12 Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Sponsors, Social Media, Neural Network Newsletter Disclaimer
    Huberman Lab
    enMay 27, 2024

    Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration

    Dr. Gary Steinberg: How to Improve Brain Health & Offset Neurodegeneration
    In this episode, my guest is Dr. Gary Steinberg, MD, PhD, a neurosurgeon and a professor of neurosciences, neurosurgery, and neurology at Stanford University School of Medicine. We discuss brain health and brain injuries, including concussion, traumatic brain injury (TBI), stroke, aneurysm, and transient ischemic attacks (TIA). We discuss key and lesser-known risk factors for brain health and explain how certain treatments and medications can improve brain health and cognitive function. We also cover novel mechanisms to improve recovery after concussions and brain injury, including the use of stem cells, temperature (mild hypothermia), and vagus nerve stimulation. Dr. Steinberg also describes new advances in neurosurgery and minimally invasive brain augmentation. This episode ought to be of interest to anyone seeking actionable tools to improve their brain health and for those seeking to improve recovery after a brain injury such as concussion, stroke, aneurysm, or TBI. For show notes, including referenced articles and additional resources, please visit hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman ROKA: https://roka.com/huberman AeroPress: https://aeropress.com/huberman LMNT: https://drinklmnt.com/huberman Timestamps 00:00:00 Dr. Gary Steinberg 00:01:44 Sponsors: Eight Sleep, ROKA & AeroPress; Subscribe on YouTube, Spotify & Apple 00:06:16 Stroke, Hemorrhage & Blood Clot 00:10:25 Blood Clots & Risk Factors, Medications, Smoking, Cholesterol 00:16:19 Heart & Brain Health; Neurosurgery & Brain Function 00:23:27 Current Technology & Neurosurgery, Minimally Invasive Techniques 00:28:13 Transient Ischemic Attacks (TIA); Spinal Cord Strokes 00:33:23 Stroke Risk: Alcohol, Cocaine & Other Drugs 00:38:24 Sponsor: AG1 00:39:55 Traumatic Brain Injury (TBI), Concussion: Sports, Testing & Recovery 00:46:45 Statins; TBI & Aspirin; Caffeine & Stroke Risk 00:48:31 Exploratory MRI: Benefits & Risks 00:51:53 Blood Pressure, Lifestyle Factors; Tool: Feeling Faint, Hydration; Sleep 00:59:52 Sponsor: LMNT 01:01:27 Chiropractic Neck Adjustment & Arterial Obstruction; Inversion Tables 01:05:16 Kids, Tackle Football, Soccer, Boxing; Mild Concussion 01:10:49 Nerve Regeneration, Stem Cells, Stroke Recovery 01:17:36 Stem Cells, Immune System, Activity 01:21:27 Injury & Recovery, Restraint Therapy 01:23:46 Neuroprotection After Injury; Mild Hypothermia 01:34:59 Platelet-Rich Plasma (PRP), Stem Cell Therapy 01:42:27 Scientific Advancements & Clinical Translation, FDA & Industry 01:47:40 Vagal Stimulation 01:53:17 Zero-Cost Support, Spotify & Apple Reviews, YouTube Feedback, Social Media, Neural Network Newsletter Disclaimer
    Huberman Lab
    enMay 20, 2024

    LIVE EVENT Q&A: Dr. Andrew Huberman at the ICC Sydney Theatre

    LIVE EVENT Q&A: Dr. Andrew Huberman at the ICC Sydney Theatre
    Recently I had the pleasure of hosting a live event in Sydney, Australia. This event was part of a lecture series called The Brain Body Contract. My favorite part of the evening was the question and answer period, where I had the opportunity to answer questions from the attendees of each event. Included here is the Q&A from our event at the ICC Sydney Theatre. Sign up to get notified about future events: https://www.hubermanlab.com/events Thank you to our sponsors AG1: https://drinkag1.com/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps 00:00 Introduction 00:15 Live Event Recap: The Brain Body Contract 00:32 Sponsors: AG1 & Eight Sleep 03:30 Q&A Session Begins: Napping and Sleep Quality 06:34 The Power of the Placebo Effect 11:31 Entering Rest and Digest State: Techniques and Tools 15:35 Muscle Growth, Learning & the Brain 20:13 Hallucinogens: Personal Experiences & Clinical Insights 27:28 The Misunderstood Effects of MDMA 27:42 Exploring the Potential of MDMA in Clinical Settings 29:25 The Complex World of Psychedelics & Mental Health 30:07 Ketamine: From Misconception to Medical Use 31:53 The Fascinating Science of DMT 33:11 Supporting Science: Funding & Future Directions 34:48 The Gut-Brain Axis: A Key to Overall Health 40:41 Sleep Patterns and Chronotypes: Personalizing Rest 42:50 Addressing ADHD & Focus in the Modern World 49:27 Closing Remarks & Gratitude Disclaimer
    Huberman Lab
    enMay 17, 2024

    Related Episodes

    Five Simple Steps to a Calmer Mind

    Five Simple Steps to a Calmer Mind

    It's no surprise that the year 2020 has more people turning to mind-body practices like yoga and meditation to find inner peace and calm. 

    Today I'm going to teach you a powerful beginner 5-step technique that can help you clear your mind and relax whenever you need it.

    You'll also learn the one key thing you need to do BEFORE you start any meditation, why listening to the wrong music can derail your calm, and how meditation has been shown to significantly improve heart health.

    Start your sound healing journey for FREE at www.donovanhealth.com

     

     

    Ep. 86: The latest research on music interventions in dementia, and two ways to get personally involved; with NIA’s Dr. Coryse St. Hillaire-Clarke

    Ep. 86: The latest research on music interventions in dementia, and two ways to get personally involved; with NIA’s Dr. Coryse St. Hillaire-Clarke

    The award-winning movie Alive Inside (2014) inspired a five-year research project that is documenting the effects of a personalized music intervention for those with dementia. Dr. Coryse St. Hillaire-Clarke of The National Institute on Aging (NIA) explains the project, which is funded by an NIA grant. We discuss other studies and developments in music interventions for dementia, including two exciting opportunities to be personally involved in policies and research on the topic. The NIA is the primary Federal agency supporting and conducting Alzheimer's disease research, which falls within the NIA's broader scientific effort to extend the healthy, active years of life.

    Links and notes related to this episode can be found at https://mpetersonmusic.com/podcast/episode86

    Connect with us:

    In-episode promos:

    How To Optimize Your Brain and Body Health

    How To Optimize Your Brain and Body Health

    How did you sleep last night? And did you get enough sleep?

    In other words, did you get enough REM sleep and deep sleep?  Because these two stages of sleep address different parts of your brain and body.

    If you don't know the answers to these questions, if you want to prioritize sleep, but have trouble falling asleep or staying asleep, this is an episode you don't want to miss.

    In this episode, I'll be reviewing:

    • What is sleep
    • The architecture of sleep
    • Why we sleep
    • The difference between deep sleep and REM sleep
    • What inhibits sleep
    • What facilitates better sleep

    Free Resources:

    RESOURCES:

    EP.87 - Emotional Detox with Sherianna Boyle, MED, CAGS, Author, Psychology, Coach

    EP.87 - Emotional Detox with Sherianna Boyle, MED, CAGS, Author, Psychology, Coach

    Welcome to the #SPAITGIRL Talk Show with Yvette Le Blowitz

    EP.87 -  Emotional Detox with Sherianna Boyle, MED, CAGS - Author, Speaker

    Sherianna Boyle, MED, CAGS, is an adjunct psychology professor, certified energy practitioner, yoga instructor, wellness expert and best selling author.

    Sherianna Boyle is the Author of Emotional Detox and the C.L.E.A.N.S.E method which is seven steps to release toxicity and energise joy.

    When we think of a detox, we usually think of a physical experience.

    But it’s not just our physical bodies that need to be cleansed of the impurities we encounter and absorb in our daily lives—it’s our minds too.

    When we find ourselves unable to process our negative emotions and feel them becoming toxic to ourselves and those around us, it’s time for an Emotional Detox, a mindful and systematic guide to freedom from these troublesome feelings.

    Sherianna Boyle talks more about what an emotional detox actually is and how we can flush out any negative feelings, to clear a path for new habits and behaviours and embrace love, acceptance and pure joy in our own life.

    Learn how to Clear your pathways, Look inward, Emit positivity, Activate, Nourish, Surrender, and Ease your way into your best self and a happier and healthier life. 

    In this episode 87 our Podcast Guest

    Sherianna Boyle, MED, CAGS

    - her personal story

    - what inspired her to write a book on Emotional Detox

    - what is an Emotional Detox

    - how can we get rid of negative feelings

    - how can we stop reacting to things that trigger our past traumas or negative experiences

    - how can we create a better relationship with our husband, wife, partner

    - how to forgive someone who has personally hurt us

    - how to love and trust again

    - how to surrender to what no longer serves our highest good

    - how to accept the now

    - how to stop comparing our now with our past life and self

    - how to become the observer of your thoughts, feelings, emotions, triggers

    - how to make peace with how you feel

    - how to create space within

    - how to cultivate a self care practice

    - how to feel less overwhelmed

    - how to feel happy again after a trumatic or hurtful event

    - how to find our true self amongst the noise of our mind chatter and the world outside and around us

    Plus we talk about so much more of course...

    Grab a copy of Sherianna Boyle, MED, CAGS books via Amazon visit *click here for our affiliated amazon link

    -----

    Hashtag #spaitgirlbookclub #spaitgirl to share the LOVE

    Now that you have been given the low down on this week's incredible podcast guest it is TIME to.......

    Tune into the #spaitgirl #podcast Episode 87- OUT NOW on Apple Podcasts 

    or Spotify Podcasts, Google Podcasts

    search for #spaitgirl on any podcast app

    --------

    Available to watch on Youtube Channel 

    Spa it Girl or Yvette Le Blowitz 

    ------

    Stay in contact with our Podcast Guest:

    Sherianna Boyle, MED, CAGS

    Website: www.sheriannaboyle.com

    ----

    IN SUPPORT - Little Random Act of Kindness 

    After you tune into this episode

    I would LOVE for you to

    - subscribe to the #spaitgirl podcast show with Yvette Le Blowitz

    - leave a 5* rating and review

    - tell a friend, family member, or anyone you meet along the way too.

    ----------

    Subscribe to #spaitgirl

    Website: www.spaitgirl.com

    Instagram: @spaitgirl

    ------

    Podcast Host 

    Yvette Le Blowitz 

    Instagram @yvetteleblowitz

    My Published Book - It Starts With Me 

    OUT NOW - ON AMAZON

    It Starts With Me by Yvette Le Blowitz *click here to grab a copy from our affiliated Amazon link

    -------

    For Your Chance To Be Featured at www.spaitgirl.com

    Email: info@spaitgirl.com with your proposal 

    Be Social - Hashtag #spaitgirl to share what you are up to - sharing is caring 

    Please note - Affiliated Links included in this spaitgirl.com blog post includes affiliated links with Amazon.com - should you order any books from Amazon.com via the links contained in this blog post spaitgirl.com will receive a small paid commission fee from Amazon.com 

    34. Collagen vs. Protein Powders with Olivia Pelaez

    34. Collagen vs. Protein Powders with Olivia Pelaez

    In this episode, Anna Marie interviews Olivia Pelaez, who is the Education Coordinator for Vital Proteins. Pelaez shares her expertise on collagen, what you should look for in collagen and when you should take it? Stay tuned to find out how and when you should be taking your collagen.  

     

    About the Guest: 

    Olivia is also a self-proclaimed 'nutrition junkie' who believes whole-heartedly that food is medicine. She received her Bachelor of Science with Honors in Nutrition and Dietetics from the University of Western Ontario and her Masters in Functional Medicine and Human Nutrition from the University of Western States. She has been with Vital since 2018 and she is super passionate about educating people on the benefits of collagen.  

     

    What this episode covers: 

    • What is the difference between collagen and regular protein shakes? 
    • Why is collagen so important to supplement with? 
    • What differences have you noticed since supplementing with collagen?  
    • What should people look for when selecting a good collagen?  
    • Is collagen good for kids?  
    • Can you overdue it on collagen? How do you know if you overdue it?  
    • How do you know if you need to supplement with collagen?