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    TASTE BUDDIES: No Sugarcoating How Sweet Affects The Brain

    en-usJuly 28, 2022

    Podcast Summary

    • Miracle Berries: Turning Sour into SweetMiracle berries can make sour foods taste sweet by binding to sweet taste receptors, but creating a sustainable and scalable solution from these berries is complex.

      Miracle berries, a plant-derived taste modifier from West Africa, can make sour foods taste sweet by binding to human sweet taste receptors when the pH is low. These berries, which come in tablet form online, contain the protein miraculin, which activates sweetness receptors, making sour foods taste like sweet lemonade or even sugar itself. However, despite the potential appeal of using miracle berries as a sugar substitute in the context of sugar intake warnings, creating a sustainable and scalable solution from these berries is a complex process.

    • Sweet Taste Signals Calories and SurvivalExcessive sugar intake can lead to inflammation in the brain, disrupting communication between neurons and affecting memory and mood.

      Our ability to taste sweet things is essential for survival as it signals the presence of calories. However, in today's world, we are exposed to an excessive amount of sugar, leading to negative effects on our bodies and brains. When a sugar molecule binds to a sweet taste receptor on the tongue, it triggers a signal to the brain, indicating the presence of calories. Throughout evolution, this mechanism helped us survive. However, modern diets filled with processed sugars can lead to an inflammatory process in the brain. This inflammation can disrupt the communication between neurons, affecting memory formation and mood. Elevated blood glucose levels can compromise the ability to process emotions. So, while enjoying sweet treats is enjoyable, it's crucial to maintain a healthy balance to avoid the potential negative consequences on our brains.

    • Impacts of High Sugar and Fat Foods on Brain Development and MotivationConsuming high sugar and high fat foods during childhood can lead to riskier food choices and impact brain development, potentially affecting motivation for healthy eating later in life. Early life stressors may exacerbate these effects.

      The consumption of high sugar and high fat foods, particularly during childhood, can have significant impacts on brain development and motivation. The Adolescent Brain Cognitive Development (ABCD) study, the largest long-term study on brain development and child health in the US, is currently exploring these links. Research suggests that children who consume high sugar and high fat foods tend to make riskier choices when it comes to food, and those who experience early life stressors are more likely to overconsume these foods. Additionally, early life stressors can shape the brain and affect motivation for food choices later in life. Despite efforts to find a healthier substitute for sugar, no perfect solution has been found yet.

    • Exploring the Complexities of Creating a Taste-Alike Sugar SubstituteResearch into miracle berries and systemic policies are potential solutions to reducing excessive sugar consumption, but creating a true sugar substitute remains a complex challenge

      Creating a sugar substitute that truly tastes and functions like sugar is a complex challenge. Current alternatives often have off-putting tastes due to bitterness or lack of sweetness. Research into miracle berries and their ability to activate sweetness in a lower pH environment shows promise, but more work is needed to develop effective formulations. While it's true that humans need calories from sugar, the issue lies in the excessive consumption of added sugars. Systemic policies, such as regulations on food industries and reductions in added sugars in medications, are necessary to address this issue. It's an uphill battle, but with collective effort, we can make progress towards reducing sugar overconsumption.

    • Making Medicine Taste BetterHistorically, adding flavors to medicines has helped people consume them more easily, and NPR invites listeners to share their personal math stories

      The use of flavored medications, coated with sugar and artificial sweeteners, can make it easier for people to consume their medicine. This practice has historical precedents, such as the use of the miracle berry in West Africa, where a spoonful of the berry could make bitter medicines more palatable. The importance of making medicine taste better is not to be underestimated, as it can significantly impact a person's willingness and ability to take their medication as prescribed. This episode of Shortwave from NPR also touched upon the invitation to listeners to share their personal stories about how math impacts their lives and the real world. If you have a favorite math problem or a moment when you realized the power of math, record yourself in a voice memo and send it to shortwave@mpr.org. Your voice could be featured in an upcoming episode.

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