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    Using AI to diagnose Dementia with Vistim Labs James Hamet + Jason LIVE at iConnections | E1757

    en-usJune 06, 2023

    Podcast Summary

    • Bringing Ideas to Life with CODA, Miro, and VEEDUse CODA for workflow integration, Miro for collaborative ideation, and VEED for video creation to bring ideas to life effectively.

      Ideas are abundant and meaningless without execution. Last night, each person in the room likely had dozens of ideas during their sleep. Collectively, that's 500 ideas, with potentially $3 billion worth of potential in them. However, ideas alone are not enough. The real value comes from turning those ideas into reality. Three tools that can help bring ideas to life are CODA, Miro, and VEED. CODA is an all-in-one dock for teams that helps bring together various workflow tools. Miro democratizes collaboration and input, helping ideas move from concept to reality. VEED makes video creation easy and accessible, allowing anyone to engage their audience effectively. AI is making significant strides in various industries, including business and generative art. However, its impact extends beyond these areas. In healthcare, AI is helping solve the diagnostic puzzle, which can be costly, invasive, and time-consuming for patients. James Amit from System Labs is working on using AI and hardware to detect Alzheimer's disease early and accurately, providing results in the same day instead of the typical 18-month wait for a PET scan. By focusing on diagnosis, AI can revolutionize neurological care and improve patients' lives.

    • Using AI and EEG for Early Alzheimer's DiagnosisAI and EEG technology could provide earlier and more accurate Alzheimer's diagnoses through measuring cognitive ability and brain damage, using non-invasive EEG devices and specific videos.

      Current methods for diagnosing Alzheimer's disease involve waiting for severe symptoms before conducting expensive and inconclusive tests like PET scans. A new approach being developed uses AI and EEG technology to measure cognitive ability and brain damage, potentially leading to earlier and more accurate diagnoses. The product, which is entirely software, requires patients to wear an already-existing EEG device and watch specific videos while the AI analyzes their brain activity to identify struggles in interpreting certain images. This non-invasive method could revolutionize the diagnostic process for neurodegenerative diseases.

    • CODA: A tool for startups to streamline projects and increase efficiencyCODA is an all-in-one solution for startups to manage projects, utilizing AI technology to analyze electrode data and predict outcomes, improving productivity, coordination, and communication.

      CODA is a comprehensive tool designed to help startups streamline their projects and increase efficiency. It allows teams to work on entire projects from start to finish in one place, reducing the need for multiple sub-par solutions and improving productivity, coordination, and communication. The AI technology behind CODA analyzes electrode data from a clinical database to make correlations and predictions, demonstrating its potential in various industries, including healthcare. The company has used this method with over 150 people internationally, including at Columbia University and LMU Munich, and has collected data from 160 patients, ranging from healthy elders to those with diagnosed Alzheimer's. The product is not yet available for consumer use, but it shows promise in revolutionizing the way startups and industries approach their projects.

    • FDA Exemptions for Medical Device Startups in Cognitive Performance AssessmentStartups in cognitive assessment can use FDA exemptions to expedite market entry by being classified as cognitive assessment aids, avoiding advanced approvals. Seek regulatory guidance to understand product's intended use and applicable codes.

      Startups in the medical device industry, specifically those focused on cognitive performance assessment, can take advantage of FDA exemptions that expedite their go-to-market strategy. By providing cognitive performance indicators through AI predictions, these companies can be classified as cognitive assessment aids, exempting them from advanced FDA approvals. However, not all products will qualify for these exemptions, and it's crucial for entrepreneurs to seek regulatory guidance to ensure they're making informed decisions. The key is to understand the intended use of the product and the specific regulatory codes that apply. While this route may not be suitable for all companies, it can provide a significant advantage for those in the cognitive assessment field. Remember, FDA exemption is just the first step; selling to doctors and hospitals still requires robust clinical data to secure their trust and business.

    • FDA Regulation Process for Medical Devices: From Band-Aids to Complex DevicesFounders can prepare for investors during FDA regulation process using Miro's pitch deck template. Miro is a versatile digital whiteboarding software for team collaboration. A medical EEG device using software analysis is launching this year, targeting dementia, Parkinson's, and traumatic brain injuries, with profitability expected in Q1 of next year.

      The FDA regulation process, which includes obtaining a 510k for medical devices, applies to various classes of medical devices, from simple ones like band-aids to complex ones like heart valves. The process can be lengthy and requires expertise, but founders can use tools like Miro's pitch deck template to prepare for investors while they go through the process. Miro is a versatile digital whiteboarding software that enables distributed and asynchronous team collaboration, making it ideal for hybrid or fully remote teams. The company is developing a medical EEG device that uses software to analyze brain activity and create reports, and they expect to launch the product and start collecting data for feedback this year, with profitability anticipated in Q1 of next year. The company also plans to expand into other disease states beyond dementia, including Parkinson's and traumatic brain injuries. The device, which looks like a sci-fi skull cap with webs, will allow clinicians to quickly assess brain activity and anticipate progression, providing valuable insights for patient care.

    • Recording Brain Activity with High-End DevicesHigh-end brain activity recording devices, though expensive, offer early detection of diseases like Alzheimer's and have applications in various industries.

      Brain activity recording devices, such as those used in clinical settings, can cost anywhere from $10,000 to $40,000. These devices, which include an amplifier, are used for various applications, including controlling computers, video games, and even cars. The technology has been successfully used in companies like Narable, which was founded by the speaker and has raised over $10 million. While the cost might seem high, early detection of diseases like Alzheimer's through these devices is possible, and they can pick up signs up to 10 years before clinical diagnosis. The good news is that the cost is less than a thousand dollars and is largely covered by insurance.

    • Early detection and prevention of Alzheimer's save costsEarly detection and prevention through meds, lifestyle changes save on Alzheimer's costs. Sleep, exercise, diet, mental stimulation, and good sleep hygiene help. Preventative meds like Galantamine, Denazapil cost $100/month.

      Early detection and prevention of Alzheimer's disease can lead to significant cost savings compared to expensive treatments for advanced stages of the disease. Preventative medications like Galantamine and Denazapil, which cost $100 or less per month, can help slow symptomatic decline. Additionally, lifestyle changes such as regular exercise, a balanced diet, mental stimulation, and good sleep hygiene can help prevent Alzheimer's. It's important to note that while genetics play a role, comorbidities, insomnia, and social isolation are significant contributors to the development of Alzheimer's. Research suggests that sleep deprivation, even as little as 2 hours per night, can increase the likelihood of developing Alzheimer's. Sleep is crucial for brain health, and getting adequate rest is essential for maintaining cognitive function.

    • AI in healthcare: A game-changer for preventative medicineAI technology is transforming healthcare by tracking and optimizing sleep and diet for elite athletes, and has the potential to detect and prevent conditions like diabetes, heart disease, and cancer through early intervention based on epigenetics and multiple data points.

      AI technology is revolutionizing the field of healthcare, particularly in the realm of preventative medicine. Sleep and diet are critical factors in the performance of elite athletes, and AI is being used to track and optimize these areas. In the broader context of AI in healthcare, the potential applications are vast, with conditions like diabetes, heart disease, and even cancer being potential targets for early detection and prevention. Epigenetics and the impact of stress and diet on gene expression are making symptom-free living a possibility. The use of AI to analyze multiple data points and identify potential health issues before they become serious is a game-changer. The future of healthcare could involve personalized preventative measures, such as warning systems for conditions like stroke, allowing individuals to take action before serious consequences occur. The power of performance medicine and the feedback loop it provides cannot be overstated, as it encourages individuals to make lifestyle changes that can significantly reduce their risk for various health issues.

    • Small, consistent healthy habits impact overall wellbeingDaily weigh-ins, monitoring nutritional intake, glucose levels, and regular physical activity can significantly improve wellbeing. Prioritize daily exercise to combat aging, sugar cravings, and Alzheimer's disease. Videos tend to go viral more often than audio clips.

      Implementing small, consistent healthy habits can have a significant impact on overall wellbeing, particularly in relation to weight management and brain health. The speaker emphasizes the importance of daily weigh-ins, monitoring nutritional intake and glucose levels, and engaging in regular physical activity, even if it means walking to the ice cream store instead of driving. Additionally, the speaker highlights the connection between aging, sugar cravings, and Alzheimer's disease, and encourages listeners to prioritize daily exercise, which has been well-documented as beneficial. The speaker also shares that they produce six video podcasts per week and while it is more expensive, videos tend to go viral more often than audio clips. If you're interested in learning more about the company, VISTAMLabs, or potentially joining their team, you can connect with James on LinkedIn or visit their website.

    • VEED: Easy Video Editing with AI Tools and TemplatesVEED simplifies video editing with automatic subtitles, background noise removal, AI tools, and hundreds of templates, enabling anyone to create professional-grade videos without requiring editing skills or spending hours learning complex software.

      VEED is a user-friendly web-based video editor that allows anyone to create professional-quality videos without requiring editing skills or spending hours learning complex software. It offers various features such as automatic subtitles, background noise removal, and AI tools to make editing faster and easier. Additionally, VEED provides hundreds of templates for users to get started quickly. Jason, the interviewee, is a well-known figure in the podcasting industry, having founded the Top 10 All In Podcast and planning the All In Summit. He started his career as a journalist and later founded companies, one of which was backed by Sequoia. He introduced Sequoia to three successful startups, Tesla, Zynga, and Twitter, but they passed on investing in them. Now, he is an angel investor and a scout for Sequoia. The interview also highlighted the impact of podcasting, which allows people to connect with their audience on a personal level and reach millions of listeners around the world.

    • Democratizing venture capital with public fundraises through 506C506C enables venture capitalists to publicly raise funds from accredited investors, increasing transparency and access to a larger pool of potential investors.

      The venture capital industry is evolving with the introduction of public fundraises through 506C, which aims to democratize venture capital by allowing entrepreneurs to raise funds from a wider audience of accredited investors. Previously, venture capitalists were restricted during the fundraising process due to regulatory quiet periods. However, with 506C, they can publicly announce their fundraising efforts and certify each accredited investor. This approach allows for greater transparency and the potential to meet and invest in a larger pool of investors. The speaker, who has had success in venture capital investments, is now raising a public fund using this method and believes it will revolutionize the industry.

    • Clear communication and a well-rounded team are keys to successEffective communication leads to better understanding and success. A team with diverse skills increases chances of success in a startup. Being open to feedback and learning from it improves approach.

      Effective communication and clarity in presenting one's strategy or ideas can lead to better understanding and success, even in the face of criticism or opposition. The speaker, a successful investor, shares his experience of feeling frustrated with the design process for his pitch deck and instead opted to write a clear and concise thesis. He also emphasizes the importance of having a team with diverse skills, such as builders, to increase the chances of success in a startup. Additionally, he mentions that being open to feedback and learning from it can help improve one's approach. Overall, the key takeaway is the importance of clear communication and having a well-rounded team in achieving success.

    • The key to successful investing in startups lies in the team's dedication and obsession with building a product that delights customers.Investing in startups requires focusing on the team's commitment, resilience, and product velocity, while providing personalized support and growing relationships.

      Ideas are abundant and meaningless without execution. The key to success in investing, especially in startups, lies in the team's dedication, resilience, and obsession with building a product that delights customers. While analyzing potential investments, venture capitalists look beyond grand strategies and focus on product velocity and personal connections. They put in the hustle, providing capital, introductions, and a network, and act as friends during tough times. The best founders generally don't need much advice, and the venture capitalist's role is to serve as a supportive service provider. The process involves meeting and investing in many people, tracking their progress, and growing positions in successful companies. With a large audience and thousands of applicants, the focus is on providing personalized attention and building strong relationships.

    • AI is revolutionizing productivity and industryAI is making workers 30%-40% more efficient yearly, impacting workforce, significant strides in various industries, expected to drop startup costs by 50%, leading to hiring freezes and cost savings for large companies.

      AI is revolutionizing productivity and industry, with the potential to make information workers 30% to 40% more efficient every year. This pace of innovation is unprecedented and will significantly impact the workforce, with those who embrace the technology likely to outperform those who don't. AI is already making significant strides in various industries, from sales and writing to programming, and is expected to drop the cost of starting a company by 50% for startups. For large companies, AI could lead to hiring freezes and significant cost savings, as they become more efficient and productive. The future is here, and those who adapt will thrive.

    • Democratization of Technology: Everyone a Data Scientist, Developer, and DesignerAdvancements in technology will lower the barrier to entry for creating apps, designing logos, and analyzing data, leading to exponential revenue growth for companies that adapt and an inclusive, innovative economy for all.

      The future of work is heading towards a direction where everyone will have the potential to become a data scientist, developer, and designer, thanks to advancements in technology. This means that the barrier to entry for creating apps, designing logos, and analyzing data will be significantly lowered. Companies that can leverage these tools effectively will likely see exponential revenue growth, while those that don't adapt may be left behind. The next decade is expected to bring about a wave of automation and AI integration, making it essential for individuals to upskill and stay ahead of the curve. This shift towards democratized technology will lead to a more inclusive and innovative economy, where everyone has the opportunity to contribute and create.

    • Returning to the basics in venture capitalVC industry is shifting focus to funding fewer companies, prioritizing team, product, and customer over excess resources and distractions, supporting true innovators

      The venture capital industry became oversaturated with large investments in recent years, leading to a wasteful and destructive environment in Silicon Valley. Constraints and pressure are necessary for great art and innovation, and the abundance of capital and resources created a surplus of "tourists" and false entrepreneurs. Now, we're returning to the basics, focusing on funding fewer companies, and prioritizing team, product, and customer over unnecessary perks and distractions. The greatest job in the world is helping founders navigate this new landscape and support the true innovators who are dogged, hardcore, and focused on their craft.

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    Woke Google Maps, how Wells Fargo is losing money on fintech, and the global AI race | E1967

    Woke Google Maps, how Wells Fargo is losing money on fintech, and the global AI race | E1967

    This Week in Startups is brought to you by…

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    *

    Todays show:

    Alex Wilhelm joins Jason to discuss woke Google Maps (1:57), Bilt & Wells Fargo dynamics (16:20), AI progress in China and Japan (32:00), and more!

    *

    Timestamps:

    (0:00) Jason and Alex kick off the show

    (1:57) Woke Google Maps

    (9:44) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at http://www.Squarespace.com/TWIST

    (16:20) Bilt and Wells Fargo fintech dynamics

    (17:00) CNBC interview with Bilt founder Ankur Jain

    (25:50) LinkedIn Ads - Get a $100 LinkedIn ad credit at http://www.linkedin.com/thisweekinstartups

    (32:00) AI progress in China and Japan

    (39:41 ) Mercury - Join 200K startups who use Mercury to operate at their best at http://www.mercury.com

    (45:09) Defining AGI and its implications

    (49:06) McDonald's AI ordering systems and their challenges

    (1:04:37) Audience question on EU's AI Act and its impact on startups

    *

    Subscribe to the TWiST newsletter: https://www.ticker.thisweekinstartups.com

    *

    Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

    *

    Mentioned on the show:

    https://www.ft.com/content/357f3c68-b866-4c2e-b678-0d075051a260

    https://www.theinformation.com/articles/openais-japanese-rival-gets-1-billion-valuation-from-silicon-valley-investors

    *

    Follow Alex:

    X: https://x.com/alex

    LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm/

    *

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    X: https://twitter.com/Jason

    LinkedIn: https://www.linkedin.com/in/jasoncalacanis

    *

    Thank you to our partners:

    (9:44) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at http://www.Squarespace.com/TWIST

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    (39:41 ) Mercury - Join 200K startups who use Mercury to operate at their best at http://www.mercury.com

    *

    Great 2023 interviews: Steve Huffman, Brian Chesky, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

    *

    Check out Jason’s suite of newsletters: https://substack.com/@calacanis

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    TikTok: https://www.tiktok.com/@thisweekinstartups

    *

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    This Week in Startups
    en-usJune 17, 2024

    Lessons in Unreasonable Hospitality with Will Guidara | E1966

    Lessons in Unreasonable Hospitality with Will Guidara | E1966

    This Week in Startups is brought to you by…

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    *

    Todays show:

    Will Guidara joins Jason to discuss the book Unreasonable Hospitality and how it relates to all businesses including startups (3:44), Will’s annual “The Welcome Conference” in NY (14:32), how the show The Bear lifted Will’s ‘NY street hotdog’ story and made it their own - which then led to his involvement with future seasons (36:19), and more!

    *

    Timestamps:

    (0:00) Will Guidara of Unreasonable Hospitality joins Jason.

    (3:44) Important premises from the book Unreasonable Hospitality and how it relates to all businesses including startups.

    (6:26) Will explains how it felt to see parts from his book appear on the hit show The Bear.

    (8:13) Iconic examples of hospitality and how it can turn customers into advocates for your brand.

    (10:04) Oracle - Take a free test drive of OCI at https://www.oracle.com/twist.

    (11:08) Powerful examples of going above and beyond for your customer.

    (14:32) Will’s annual “The Welcome Conference” in NY.

    (20:57) DevSquad - Get an entire product team for the cost of one US developer plus 10% off at http://www.devsquad.com/twist

    (22:13) Jason shares an anecdote of how he helps others.

    (24:17) Will and Jason riff on interesting examples of unreasonable hospitality, including one that should exist for airplane passengers.

    (30:44) LinkedIn Ads - Get a $100 LinkedIn ad credit at http://www.linkedin.com/thisweekinstartups

    (32:12) A perspective shift that changes the value of call centers.

    (36:03) How the show The Bear lifted Will’s ‘NY street hotdog’ story and made it their own - leading to his involvement for future seasons.

    (40:21) Will feels that The Bear was able to craft and articulate his message spot on in one of their best episodes.

    (42:22) How to gain from the addictive personality traits in the restaurant business.

    (51:15) The “Chicken for Two” at the NoMad hotel.

    (53:31) Breaking down the state of tipping culture and how its removal from Eleven Madison Park was highly successful.

    *

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    Check out Unreasonable Hospitality: https://www.unreasonablehospitality.com/

    Sign up for Will’s newsletter: https://www.unreasonablehospitality.com/newsletter

    Check out “The Welcome Conference”: https://www.thewelcomeconference.com/

    Check out Will’s hospitality agency “Thank You”: https://www.thankyou.nyc/

    *

    Follow Will:

    X: https://x.com/wguidara

    LinkedIn: https://www.linkedin.com/in/willguidara/

    *

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    X: https://twitter.com/Jason

    LinkedIn: https://www.linkedin.com/in/jasoncalacanis

    *

    Thank you to our partners:

    (10:04) Oracle - Take a free test drive of OCI at https://www.oracle.com/twist.

    (20:57) DevSquad - Get an entire product team for the cost of one US developer plus 10% off at http://www.devsquad.com/twist

    (30:44) LinkedIn Ads - Get a $100 LinkedIn ad credit at http://www.linkedin.com/thisweekinstartups

    *

    Great 2023 interviews: Steve Huffman, Brian Chesky, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

    *

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    *

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    TikTok: https://www.tiktok.com/@thisweekinstartups

    *

    Subscribe to the Founder University Podcast: https://www.founder.university/podcast

    This Week in Startups
    en-usJune 14, 2024

    Inflation cools, how Waymo handled a crash, and the next startups to go public | E1965

    Inflation cools, how Waymo handled a crash, and the next startups to go public | E1965

    This Week in Startups is brought to you by…

    Eight Sleep. Good sleep is the ultimate game changer. The newest generation of the pod, the Pod 4 ultra has arrived. Head to https://www.eightsleep.com/twist and use code TWIST to get $350 off the Pod 4 Ultra.

    Zendesk. The best customer experiences are built with Zendesk. Qualifying startups can join their Startup program and get Zendesk products free, for six months! Visit http://www.zendesk.com/twist today to get started.

    CLA. Innovation takes balance. CLA's CPAs, consultants, and wealth advisors can help you get from startup to where you want to end up. Get started now at ⁠https://www.claconnect.com/tech

    *

    Todays show:

    Alex Wilhelm joins Jason to discuss Waymo crash implications (3:53), Apple's AI announcements post-WWDC (17:17), inflation cooldown (27:21), and more!

    *

    Timestamps:

    (0:00) Jason and Alex kick off the show

    (3:53) How Waymo handled a crash and self-driving car standards

    (8:08) Eight Sleep - Head to https://www.eightsleep.com/twist and use code TWIST to get $350 off the Pod 4 Ultra.

    (10:04) Car safety technology

    (17:17) Apple's AI announcements and stock impact

    (25:41) Zendesk - Get six months free at

    http://www.zendesk.com/twist

    (27:21) Inflation update: Recent CPI data and its implications

    (33:34) High interest rate environment and venture capital

    (40:48) CLA - Get started with CLA's CPAs, consultants, and wealth advisors now at ⁠https://claconnect.com/tech

    (42:12) 10 companies most likely to IPO

    *

    Subscribe to the TWiST newsletter: https://www.ticker.thisweekinstartups.com

    *

    Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

    *

    Mentioned on the show:

    https://www.reddit.com/r/SelfDrivingCars/comments/1cxo27o/waymo_car_crashes_into_pole/

    https://www.theverge.com/2024/6/12/24175489/waymo-recall-telephone-poll-crash-phoenix-software-map

    https://techcrunch.com/2024/02/13/waymo-recall-crash-software-self-driving-cars/

    https://techcrunch.com/2024/06/12/waymo-second-robotaxi-recall-autonomous-vehicle/

    https://www.cnbc.com/quotes/AAPL?qsearchterm=aapl

    https://www.bls.gov/news.release/cpi.nr0.htm

    https://x.com/ashugarg/status/1800658425040253309

    https://www.cnbc.com/quotes/US2Y

    https://www.wsj.com/livecoverage/fed-meeting-fomc-interest-rate-decision-cpi-inflation-june-2024/card/traders-firmly-expect-a-rate-cut-in-september-q8qGgjh8jorUx56RBpK8

    https://kalshi.com/markets/ratecutcount/number-of-rate-cuts#ratecutcount-24dec31

    https://www.cnbc.com/2024/06/12/fed-meeting-today-on-interest-rate.html

    https://www.crunchbase.com/organization/databricks

    https://www.crunchbase.com/organization/gusto

    https://archive.is/fGJav#selection-2217.0-2226.0

    https://www.crunchbase.com/organization/shein-b79e

    https://www.sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=0001514587&owner=exclude&count=40&hidefilings=0

    https://www.crunchbase.com/organization/turo

    *

    Follow Alex:

    X: https://x.com/alex

    LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm/

    *

    Follow Jason:

    X: https://twitter.com/Jason

    LinkedIn: https://www.linkedin.com/in/jasoncalacanis

    *

    Thank you to our partners:

    (8:08) Eight Sleep - Head to https://www.eightsleep.com/twist and use code TWIST to get $350 off the Pod 4 Ultra.

    (25:41) Zendesk - Get six months free at http://www.zendesk.com/twist

    (40:48) CLA - Get started with CLA's CPAs, consultants, and wealth advisors now at ⁠https://claconnect.com/tech

    *

    Great 2023 interviews: Steve Huffman, Brian Chesky, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

    *

    Check out Jason’s suite of newsletters: https://substack.com/@calacanis

    *

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    Instagram: https://www.instagram.com/thisweekinstartups

    TikTok: https://www.tiktok.com/@thisweekinstartups

    *

    Subscribe to the Founder University Podcast: https://www.founder.university/podcast

    This Week in Startups
    en-usJune 12, 2024

    Apple’s WWDC 2024: Reactions, Highlights & Breakdowns with Jason and Alex | E1964

    Apple’s WWDC 2024: Reactions, Highlights & Breakdowns with Jason and Alex | E1964

    This Week in Startups is brought to you by…

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    LinkedIn Jobs. A business is only as strong as its people, and every hire matters. Go to https://www.linkedin.com/twist to post your first job for free. Terms and conditions apply.

    The Equinix Startup program offers a hybrid infrastructure solution for startups, including up to $100K in credits and personalized consultations and guidance from the Equinix team. Go to https://www.equinixstartups.com to apply today.

    *

    Timestamps:

    (0:00) Jason and Alex kick off the show

    (1:50) Jumping into the keynote from Apple and whether or not it impressed.

    (5:24) “Apple Intelligence” has landed!

    (8:32) Reactions to the new Siri.

    (10:00) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at http://www.Squarespace.com/TWIST

    (12:42) The importance of Apple’s addition of “on-screen awareness”.

    (16:30) Breakdown of Apple’s use of data with their AI.

    (19:48) LinkedIn Jobs - Post your first job for free at https://www.linkedin.com/twist

    (23:53) ChatGPT’s integration with Siri.

    (26:32) Unpacking the “free” use of ChatGPT with Apple products.

    (30:01) Equinix - Join the Equinix Startup Program for up to $100K in credits and much more at https://deploy.equinix.com/startups

    (31:07) Discussing the relationships between OpenAI and Microsoft and now Apple.

    (34:44) More “ooohs” and “ahhhs” from Apple’s new Image Playground.

    (40:25) Jason breaks down other key announcements from WWDC 2024 including a password manager and Apple TV’s new “Insights”.

    *

    Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

    *

    Links:

    Watch Apple’s WWDC 2024 Keynote: https://developer.apple.com/videos/play/wwdc2024/101/

    Article on Fearless Fund: https://www.bloomberg.com/opinion/articles/2024-06-06/the-fearless-fund-should-keep-fighting-racism-in-venture-capital

    *

    Follow Alex:

    X: https://x.com/alex

    LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm/

    *

    Follow Jason:

    X: https://twitter.com/Jason

    LinkedIn: https://www.linkedin.com/in/jasoncalacanis

    *

    Thank you to our partners:

    (10:00) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at http://www.Squarespace.com/TWIST

    (19:48) LinkedIn Jobs - Post your first job for free at https://www.linkedin.com/twist

    (30:01) Equinix - Join the Equinix Startup Program for up to $100K in credits and much more at https://deploy.equinix.com/startups

    *

    Great 2023 interviews: Steve Huffman, Brian Chesky, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

    *

    Check out Jason’s suite of newsletters: https://substack.com/@calacanis

    *

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    Instagram: https://www.instagram.com/thisweekinstartups

    TikTok: https://www.tiktok.com/@thisweekinstartups

    *

    Subscribe to the Founder University Podcast: https://www.founder.university/podcast

    This Week in Startups
    en-usJune 11, 2024

    The state of seed, the first TWIST500 startups, and the impact of anonymous apps on society | E1963

    The state of seed, the first TWIST500 startups, and the impact of anonymous apps on society | E1963

    This Week in Startups is brought to you by…

    Attio. A radically new CRM for the next era of companies. Head to https://attio.com/twist to get 15% off for your first year.

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    .Tech Domains - Don’t miss our “Jam with JCal” contest! To apply and get more details go to https://www.jamwithjcal.tech brought to you by .tech domains.

    *

    Todays show:

    Alex Wilhelm joins Jason to discuss concerns about the app "Fizz" (12:24), the state of seed (31:35), the first TWIST500 startups (58:58), and more!

    *

    Timestamps:

    (0:00) Jason and Alex kick off the show

    (11:15) Attio - Head to https://attio.com/twist⁠ to get 15% off for your first year.

    (12:24) Concerns about the app "Fizz" and the use of anonymity in social media apps

    (19:14) The impact of anonymous apps on society, parenting concerns, and the responsibility of investors in harmful tech startups

    (23:16) The case for banning smartphones in schools

    (30:19) OpenPhone - Get 20% off your first six months at https://www.openphone.com/twist⁠

    (31:35) The state of seed

    (35:33) Impact of AI on startup efficiency

    (38:17) .Tech Domains - Apply for the “Jam with JCal” contest today at https://www.jamwithjcal.tech

    (39:45) The variety of seed deals

    (45:13) How to leave and join a rival company legally

    (58:58) The first TWIST500 startups

    (1:05:48) Impact of AI on journalism and media companies

    *

    Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

    *

    Mentioned on the show:

    https://www.wsj.com/tech/personal-tech/fizz-is-the-latest-campus-gossip-app-it-took-two-days-to-shake-up-one-high-school-1d59ffd4

    https://www.businessinsider.com/gen-z-fizz-app-anonymous-messaging-cyber-bullying-vermont-2024-6

    https://techcrunch.com/2023/08/10/insiders-bet-more-on-fizz-a-social-network-that-has-now-bubbled-up-at-80-college-campuses/

    https://x.com/JonHaidt/status/1799525595509850522

    https://techcrunch.com/2017/04/28/yik-yak-shuts-down-after-square-paid-1-million-for-its-engineers/

    https://x.com/Jason/status/1799868195899376014/photo/1

    https://techcrunch.com/2024/06/07/y-combinator-yc-startups-tiny-seed-rounds-vc-investors-not-interested/

    https://x.com/dhh/status/1799427898652389827

    https://ticker.thisweekinstartups.com/

    https://www.forbes.com/sites/sarahemerson/2024/06/07/buzzy-ai-search-engine-perplexity-is-directly-ripping-off-content-from-news-outlets/

    https://techcrunch.com/2022/06/24/zendesk-drama-concludes-with-10-2-billion-private-equity-acquisition

    *

    Follow Alex:

    X: https://x.com/alex

    LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm/

    *

    Follow Jason:

    X: https://twitter.com/Jason

    LinkedIn: https://www.linkedin.com/in/jasoncalacanis

    *

    Thank you to our partners:

    (11:15) Attio - Head to https://attio.com/twist⁠ to get 15% off for your first year.

    (30:19) OpenPhone - Get 20% off your first six months at https://www.openphone.com/twist

    (38:17) .Tech Domains - Apply for the “Jam with JCal” contest today at https://www.jamwithjcal.tech

    *

    Great 2023 interviews: Steve Huffman, Brian Chesky, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

    *

    Check out Jason’s suite of newsletters: https://substack.com/@calacanis

    *

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    TikTok: https://www.tiktok.com/@thisweekinstartups

    *

    Subscribe to the Founder University Podcast: https://www.founder.university/podcast

    This Week in Startups
    en-usJune 11, 2024

    Great Builders & Success First with Intercom’s Eoghan McCabe | E1962

    Great Builders & Success First with Intercom’s Eoghan McCabe | E1962

    This Week in Startups is brought to you by…

    LinkedIn Ads - To redeem a $100 LinkedIn ad credit and launch your first campaign, go to http://www.linkedin.com/thisweekinstartups

    .Tech Domains - Don’t miss our “Jam with JCal” contest! To apply and get more details go to https://www.jamwithjcal.tech brought to you by .tech domains.

    Northwest Registered Agent - Northwest Registered Agent will form your business quickly and easily. In just 10 clicks and 10 minutes, set up your entire business identity—name, address, mail service, phone, email, website, and domain. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist today.

    *

    Todays show:

    Intercom’s Eoghan McCabe joins Jason to discuss: the state of the business at Intercom and his return as CEO (8:33), the future of customer service with AI (24:28), what makes a great manager (59:36), and more!

    *

    Timestamps:

    (0:00) Intercom’s Eoghan McCabe joins Jason. (1:50) Family history of the two McCabe’s: Jason and Eoghan. (5:49) The kindness and dedication of Intercom’s co-founder Des Traynor. (8:33) What Intercom is, the state of the business and Eoghan’s return as CEO. (10:41) LinkedIn Ads - Get a $100 LinkedIn ad credit at http://www.linkedin.com/thisweekinstartups (12:37) Looking at overlap and adjacencies when you are building SaaS products. (16:36) The brilliance of the pre-seed pricing model, and is it broken? (19:47) .Tech Domains - Apply for the “Jam with JCal” contest today at https://www.jamwithjcal.tech (22:16) What is next for companies with. SaaS-based pricing. (24:28) The future of customer service and AI. (30:30) Northwest Registered Agent - For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist today. (36:09) Expectations from AI one year from now. (45:23) Breaking down the negative press and social reaction to the Humane Pin. (52:34) What the world will look like as conversational AI develops. (59:36) What makes a great manager and the “return of the king” at Intercom.

    *

    Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

    *

    Check out Intercom: https://www.intercom.com/

    *

    Follow Eoghan:

    X: https://x.com/eoghan

    LinkedIn: https://www.linkedin.com/in/eoghanmccabe/

    *

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    X: https://twitter.com/Jason

    LinkedIn: https://www.linkedin.com/in/jasoncalacanis

    *

    Thank you to our partners:

    (10:41) LinkedIn Ads - Get a $100 LinkedIn ad credit at http://www.linkedin.com/thisweekinstartups

    (19:47) .Tech Domains - Apply for the “Jam with JCal” contest today at https://www.jamwithjcal.tech

    (30:30) Northwest Registered Agent - For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist today.

    *

    Great 2023 interviews: Steve Huffman, Brian Chesky, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

    *

    Check out Jason’s suite of newsletters: https://substack.com/@calacanis

    *

    Follow TWiST:

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    TikTok: https://www.tiktok.com/@thisweekinstartups

    *

    Subscribe to the Founder University Podcast: https://www.founder.university/podcast

    This Week in Startups
    en-usJune 08, 2024

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    Cómo desarrollar una mentalidad de abundancia y perder el miedo al dinero, con Nieves Villena | Episodio 307

    Cómo desarrollar una mentalidad de abundancia y perder el miedo al dinero, con Nieves Villena | Episodio 307

    ►► https://www.oscarfeito.com/clase ◄◄ ¡Muy buenas! Me alegro de que hayas decidido acompañarme una semanita más en La Academia de Marketing Online: TU podcast sobre marketing digital, negocios en Internet, y los valientes emprendedores que los construyen. En el programa de hoy vamos a tratar un problema que está bastante más arraigado de lo que yo pensaba. Es lo típico que piensas que nunca te pasará a ti, ¡hasta que te pasa! Y créeme, a medida que tu negocio va creciendo, la probabilidad de que te toque aumenta. Verás, prácticamente todos los emprendedores tienen miedo al fracaso (especialmente cuando están empezando) pero lo que nunca se imaginan es que en algún momento probablemente también van a tener miedo al éxito y a ganar dinero. A lo largo de los últimos 300 y pico episodios he intentado hacerte ver que el éxito no sólo implica ganar mucho dinero, sino también otras cosas como la libertad de poder trabajar cómo, cuándo, y desde dónde tú quieras. Pero también te he dicho que no tengo nada en contra del dinero, y desde luego ganar dinero no está reñido con aportar valor. Son dos cosas perfectamente compatibles, y de hecho ganar dinero suele ser una consecuencia natural de aportar valor. Para hablar de las mentalidades de escasez y abundancia, y de los prejuicios que rodean al dinero, hoy nos acompaña Nieves Villena. Nieves es economista como yo, coach de educación financiera, autora, e impulsora del movimiento Felicidad Económica; una iniciativa que nació con la misión de ayudar a las personas a tener una buena relación con el dinero y alinear sus valores con su economía. En el programa de hoy vas a conocer los 4 factores clave para alcanzar la felicidad económica, cosas que pueden poner en peligro ese equilibrio, por qué tantas personas tienen crometofobia (fobia al dinero), cómo vivir con la incertidumbre, metodologías para poner un precio justo a tus servicios, trucos para sentirte bien con tus precios aunque a otros les parezcan caros, la única pregunta que debes hacerte antes de ofrecer algo gratis, y secretos para convertir una habilidad o conocimiento en un negocio rentable y gratificante. Si te gusta La Academia de Marketing Online, puedes dejarme un comentario amable en tu plataforma de podcasts favorita y apuntarte en https://www.oscarfeito.com para recibir más contenidos, recursos y formación de marketing online. Este episodio está patrocinado por Webempresa (¡mi hosting de confianza!) Contrata tu espacio de alojamiento web rápido, seguro y flexible con un descuento del 25% en https://www.oscarfeito.com/webempresa y llévate un año de dominio gratis y mi último libro para emprendedores de regalo. Gracias por escuchar, ¡y hasta la próxima semana!

    Prof G Markets: Why TikTok Will Be Spun, Credit Suisse, the Big Bitcoin Bet, and Blank Street Coffee

    Prof G Markets: Why TikTok Will Be Spun, Credit Suisse, the Big Bitcoin Bet, and Blank Street Coffee
    This week on Prof G Markets, Scott explains why he thinks TikTok is headed for a spin-out rather than a ban. He then breaks down Credit Suisse’s spectacular fall from grace and shares his thoughts on the million dollar bet on bitcoin and hyper inflation. We close out with a look at Blank Street Coffee’s brand strategy after its latest funding round. Dig further: read Fast Company's story on Blank Street Coffee. Learn more about your ad choices. Visit podcastchoices.com/adchoices

    369. What Consumer Founders Often Get Wrong, How to Build a Culture that Breeds Creativity, and Scaling Bark to IPO (Henrik Werdelin)

    369. What Consumer Founders Often Get Wrong, How to Build a Culture that Breeds Creativity, and Scaling Bark to IPO  (Henrik Werdelin)

    Henrik Werdelin of BARK joins Nate to discuss What Consumer Founders Often Get Wrong, How to Build a Culture that Breeds Creativity, and Scaling Bark to IPO. In this episode we cover:

    • The Founding of Bark
    • Tips for Consumer Founders
    • Breeding a Creative Culture
    • The Path to IPO

    Missed a recent episode? Go to The Full Ratchet blog and catch up!

    #68 Nachhaltigkeit als Trend? – Benjamin Sadler, Erlich Textil

    #68 Nachhaltigkeit als Trend? – Benjamin Sadler, Erlich Textil
    Benjamin Sadler und Sarah Heuberger | Benjamin Sadler ist der Gründer von Erlich Textil. Seit 2016 produziert das Startup nachhaltige Kleidung und Dessous. Damals war Nachhaltigkeit noch eine Nische, inzwischen ist das Thema Mainstream geworden. Davon hat Erlich profitiert. Mittlerweile präsentieren aber auch viele große Konzerne ihre grüne Seite. Sadler zeigt sich davon wenig beeindruckt. Dennoch hat er sich mit anderen Nachhaltigkeits-Startups wie Everdrop zu der Initiative „Startups for Tomorrow“ zusammengeschlossen. Erlich Textil ist bislang nur gebootstrapt, das soll auch erst mal so bleiben. Ob sich Nachhaltigkeit und Wagniskapital für Sadler gänzlich ausschließen, erzählt der Gründer im Podcast.