Causes or Cures

In this episode of Causes or Cures, Dr. Eeks chats with Dr. Kirk Schneider about his new book Life-Enhancing Anxiety: Key to a Sane World.  In the podcast, Dr. Schneider tells us about himself and his own struggle with anxiety and how that got him on the path to discovering life-enhancing anxiety. He explains how we get from a state of anxiety to a state of Awe and why it's important that we go through that entire (often difficult) process and not plug or drug it away. He discusses ways to overcome the fear of uncertainty, COVID and life-enhancing anxiety, the shortcomings of Positive Psychology and even how life-enhancing anxiety can be used to bridge political divides.

Dr. Schneider PhD is a licensed psychologist and leader for contemporary existential-humanistic psychology. He was a 2022 Candidate for President of the American Psychological Association and cofounder and current president of the Existential-Humanistic Institute. He is a presenter of the bridge-building dialogue approach the Experiential Democracy Dialogue and a trained moderator for the conflict mediation group, Braver Angels. He is also a faculty member at Columbia University and Saybrook University. You can learn more about him and his book here.

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In this episode of Causes or Cures, Dr. Eeks chats with Dr. Andrew Sikora about the link between HPV, the most common sexually-transmitted disease, and head and throat cancers in men. While we hear more about HPV-linked cervical cancer in women, Dr. Sikora will discuss the  types of cancers HPV causes in men, risk factors, signs and symptoms, how it is treated once diagnosed, and prognosis after treatment. He will also talk about prevention and the HPV vaccine.
Dr. Sikora is professor and director of Research in the Department of Head and Neck surgery at University of Texas M.D. Anderson Cancer Center. He is also the Co-Deputy Division Head for Research in the Division of Surgery at M.D. Anderson Cancer Center.
His clinical expertise is in throat cancer and HPV-related heaed and neck cancers and his research focuses on tumor immunology and immunotherapies for cancer. You can learn more about him here.

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In this episode of Causes or Cures,  Dr. Eeks chats with filmmaker and documentarian David Krissman about his investigative podcast series, "The Great Social Experiment," about America's only experiment with universal healthcare, the treatment of patients with kidney failure.
David takes us back to 1972, when congress guaranteed healthcare coverage for people with kidney failure regardless of race, socioeconomic status and age. And while on the surface, this sounds like a great and altruistic endeavor..., David describes why it is a cautionary tale of inequity, faulty decisions  on life-or-death matters, putting profits first, questionable incentives and at the core, a cautionary tale about what drives human behavior.  Throughout the podcast, David references media reports, government data, interviews with prominent experts and kidney patients. So fasten your seatbelts, because this is an incredible story by an amazing storyteller. (And after you listen to this, absolutely check out David's podcast here.)

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In this episode, Dr. Eeks chats with Dr. Nicholas Seyfried about his research on a protein(s) in the brain that may hold the key to making people resilient to Alzheimer's Disease, a growing concern in western nations with aging populations and those who have a family history of the disease.
In the podcast, Dr. Seyfried discusses what the pathological hallmarks are of Alzheimer's Disease and why cognitive impairment happens. He then describes why certain proteins in the brain, with a special focus on one called Neuritin, may make people resilient to Alzheimer's and how approaches to Alzheimer's disease may evolve over the next several years. He also discusses evidence-based prevention strategies that are good for everyone to know.

Dr. Seyfried is director of the Emory Integrated Proteomics Core at Emory University School of Medicine  and a professor in the department of biochemistry. The Seyfried Lab at Emory focuses on the relationship between proteomics and biology to tackle Alzheimer's Disease and other neurodegenerative disorders.

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There has been recent reports and concerning articles suggesting that COVID-19 is leading to an uptick of new cases of Type 1 Diabetes in kids but is this potential link something parents and kids have to worry about?
Dr. Lars Stene joins Dr. Eeks on the podcast to discuss risk factors for Type 1 Diabetes and the trend of diagnosing new cases in kids over the last several years. He then discusses the potential, talked-about link between COVID and Type 1 Diabetes and provides his perspective on the current evidence. He discusses relative risk vs absolute risk (a good lesson for everyone), his current research on risk factors for Type 1 Diabetes and also talks about the "exposome."
Dr. Stene is a senior researcher at the Norwegian Institute of Public Health. For over 20 years, his focus is researching environmental factors, infections, nutritional factors and gene-environment interactions that may be risks for Type 1 Diabetes.  You can learn more about his work here.
And thank you to everyone who leaves a review and rating for the podcast! :)

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In this episode of Causes or Cures, Dr. Eeks chats with Dr. Ari Green about the latest thinking on what causes Multiple Sclerosis (MS) and who it impacts most, current treatment approaches, and research on potential new treatments involving remylenation therapies. He chats about the ReBUILD trial and something called the "Myelin Water Fraction" and how it can be used to measure remylenation. He also discusses the latest evidence on preventive factors for MS.
Dr. Green is a neurologist and neuro-ophthalmologist and medical director of the UCSF Multiple Sclerosis Center. He is also director of the UCSF Neurodiagnostic Center. His research focus is on reparative treatments for people with MS and slowing down neurodegeneration. You can learn more about him here.

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In this episode of Causes or Cures, Dr. Eeks chats with Dr. Tom Parsons about his study called The Weight of New York City, Possible Contributions to Subsidence from Anthropogenic Sources published in Earth's Future. He tells us what subsidence is and how it is measured, how and by how much the skyscrapers and buildings of NYC are contributing to it, why we should care about it, and what the potential short-term and long-term implications are. He talks about the potential implications from a "One Health" perspective, specifically in the realm of how our environment impacts our health. He also talks about what his study shows versus how it was presented by many media outlets, serving as an interesting case study for those in the scientific communications field.
Dr. Tom Parsons earned his PhD in geophysics from Stanford University and is a Research Geophysicist at the US Geological Survey in Menlo Park, California. You can learn more about his work, publications and research interests here.

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In this episode of Causes or Cures, Dr. Eeks chats with Dr. Lance Price about his recent study published in One Health on the link between the meat we eat and urinary tract infections (UTIs).
In the podcast, he explains how he conducted the study and breaks down the more technical stuff so that it is understandable. He discusses the results of his work, antibiotic resistance, the types of meat most significantly linked to UTIs and how eating and preparing these types of meat may lead to UTIs. Then he talks about preventive strategies on the individual level and the population level.
Dr. Lance Price  is a professor at George Washington University's School of Public Health in Washington DC and the founding director of the Antibiotic Resistance Action Center. You can learn more about him here.


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In this episode of Causes or Cures, Dr. Eeks chats with Dr. Stephanie James about the potential use of genetically modified mosquitoes (GMMs) to fight diseases that mosquitoes carry and spread, such as Malaria and Dengue Fever. 

In the podcast, Dr. James provides an overview on GMMs, as well as what something called Gene Drive Modified Mosquitoes (GDMMs) are. She talks about the current state of research, testing, and describes the GeneConvene Global Collaborative "GeneConvene", which was created to advance best practices and informed decision making for developing GMMs and GDMMs. She talks about the potential benefits versus the potential risks, how they are conducting risk assessments, how they plan to test GMMs, the ethical and safety concerns, and how local communities will be included in the decision-making process. 

Dr. James is the Senior Scientific Advisor, Population Health Science at the Foundation for the National Institutes of Health. She helps lead the work being conducted by the  GeneConvene Global Collaborative, has a doctorate in microbiology and a background in research on parasitic disease. She’s also led global health programs at the National Institute of Allergy and Infectious Diseases/NIH and the Ellison Medical Foundation.

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In this episode of Causes or Cures, Dr. Eeks chats with Dr. Comninos about Hypoactive Sexual Desire Disorder (HSDD) and his and his team's research on a potential new treatment called Kisspeptin. He will discuss prevalence, diagnosis, symptoms, how the diagnosis may be misdiagnosed as Erectile Dysfunction Disorder, and current treatment approaches to HSDD. In detail, he'll describe what Kisspeptin is and how it might help. He'll also talk about the clinical trials he has conducted involving both men and women diagnosed with HSDD and how well Kisspetin worked in those clinical trials.
Dr. Comninos is a Consultant Endocrinologist at Imperial College London where he also leads the Imperial Endocrine Bone Unit. He has authored over 75 clinical and translational publications in reproductive endocrinology, with a focus on reproductive hormones and their influence on both behavior and bones. You can learn more about him here.

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In this episode of Causes or Cures, Dr. Eeks chats with Dr. Andrei Gudkov and Dr. Joseph Wakshlag about their research on extending a dog's lifespan. They both are part of a group of scientists at Vaika, a non-profit medical research organization that is dedicated to extending the lifespan of domestic animals. In the podcast, they will discuss the aging process, how it might be reversed and how some of the things they are learning may apply to humans too. They will also talk about some of the research they are doing, including testing drugs to slow or prevent the aging process in retired sled dogs that were in kennels around the US and are now living out their retirement on spacious grounds in upstate NY. You will hear more about the dogs and their way of life in the podcast too. 

Dr. Gudkov is one of the founders of Vaika and a professor of oncology and senior vice president of research technology and innovation at Roswell Park Cancer Center. Dr. Wakshlag is a veterinarian with Cornell University and the medical director of this "sled dog study."  

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On a topic near and dear to her, in this episode of Causes or Cures, Dr. Eeks chats with "misinformation scientist" Dr. Sacha Altay on what we are getting wrong about misinformation. This podcast will focus on his and his peers' paper published in the journal Social Media and Society  titled Misinformation on Misinformation: Conceptual and Methodological Challenges. His article identifies 6 big misconceptions about misinformation and provides a lot to think about when it comes to our current aproaches to identifying and managing misinformation. 
In the podcast, Sacha will discuss some of the misconceptions about misinformation when it comes to prevalence and circulation, as well as misconceptions associated with its impact and reception. Essentially, concerns with how we are measuring the impact of misinformation and communicating that to the public. He will then discuss how the aformentioned things are associated with misinterpretation of research results. Finally, he will suggest a better path forward when it comes to misinformation. 

Dr. Altay  is an experimental psychologist working on misinformation, misperceptions, and (dis)trust. After completing his PhD in Cognitive Science at the École Normale Supérieure in Paris, he did a postdoc in Oxford at the Reuters Institute. 
As "misinformation policies"  is a "triggering" topic for many,  I request that you listen with a few deep breaths and a curious mind. 

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In this episode of Causes or Cures, Dr. Eeks chats with Dr. Naveed Sattar, a clinician, researcher, and professor of metabolic medicine at the Institute of Cardiovascular and Medical Sciences at the University of Glasgow and a leading expert in diabetes and cardiovascular disease research.
 In this podcast, he discusses the most accurate ways to measure body fat and why that matters, and he talks about the "obesity paradox", what that is and how it unravels when using more accurate measures of body fat...particularly when it comes to a specific kind of heart failure. (If you are interested, you can read his study on it here.)
He discusses how tackling chronic diseases without specifically focusing on and tackling excess weight leads to significantly more problems. (And you can read his study on that topic here.) He shares his views and concerns on the new obesity medications that are trending in the news, and finally, what  a good, population-level approach to obesity might look like.
You can read his bio here. 

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In this episode of Causes or Cures, Dr. Eeks chats with Dr. Victor Tseng about his and his team's study on how AI (ChatGPT) came close to passing the United States Medical Licensing Exams (USMLE), tests that all medical doctors must take and pass in order to practice medicine in the US. The study was published in Plos Digital Health here.
Dr. Tseng will tell us more about what ChatGPT is and its current capabilities, how they set up the study to test its performance on the USMLE, results of the study, future studies his company may perform, and perhaps most importantly, where ChatGPT could take medicine and public health in the future, while highlighting some of the major ethical and philosophical concerns. Will robots replace us?!? Let's see...
Dr. Tseng is a practicing pulmonologist (lung doctor) and the Medical Director and Executive Vice President for AnsibleHealth, a digital theranostics and AI-enhanced medical practice focused on care for diseases of the lungs.

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Would you ever donate your kidney to a stranger?
In this episode of Causes or Cures, Dr. Eeks chats with Elaine Perlman, Director of Waitlist Zero, an organization with the mission of representing kidney donors and ending the waitlist by making it easier for living donors to donate a kidney. Elaine will walk us through her journey (from start to finish) of donating her kidney to a stranger. She'll also tell us about the journey of her son, who donated his kidney when he was just a teenager.
Elaine will also explain what the "kidney crisis" is, how long the wait on the waitlist is, and the cost to living donors, a burden which Waitlist Zero hopes to decrease. Finally,  she'll talk about the biggest reason people give for donating a kidney to a stranger, and the main reasons people give for not wanting to do it.

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In this episode of Causes or Cures, Dr. Eeks chats wit Dr. Michael Santos about the A-PLUS trial, published in The New England Journal of Medicine, which looked at the effects of a cheap, widely available antibiotic, Azithromycin, in preventing sepsis and death in women during childbirth in low- to middle-income countries. Dr. Santos will explain the prevalence and life-threatening nature of sepsis in women during childbirth, particularly in low-resource settings. He will discuss what they knew about Azithromycin and maternal sepsis prior to the study, how they recruited for this study and conducted it, the results they found, and the wider public health implications.

Dr. Santos is Vice President of Science at the Foundations for the National Intitutes of Health (FNIH)  and was in charge of the work FNIH did on the A-PLUS trial. He was previously Deputy Director of the Global Health program of the Bill & Melinda Gates Foundation.


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In this episode of Causes or Cures, Dr. Eeks chats with Dr. Brennen McKenzie, a veterinarian, epidemiologist and Director of Veterinary Medicine at Loyal, a clinical-stage veterinary medicine company developing drugs to prolong the lifespan and healthspan of dogs.
He discusses the aging process in dogs, age-related biomarkers, and the link between dog size (big vs small) and lifespan. He explains what a dog's "methylation age" is, how that relates to "epigenetics" and  how that is similar to and differs from a dog's chronological age. He talks about the studies Loyal is conducting and the drugs they are developing to prolong a dog's lifespan. (You may be able to enroll your dog in a study, right from home, if interested!) Finally, he describes when he thinks we might see a "noticeable" difference in a dog's lifespan. 

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In this episode of Causes or Cures, Dr. Eeks chats with Dr. Anushka Ataullahjan about her research on the polio eradication efforts in Pakistan. Wild polio is still endemic in Pakistan, and Dr. Ataullahjan will discuss different eradication programs and initiatives they've tried over the years and the different barriers they've met, including threats of insecurity and  people's beliefs and concerns. She'll discuss how various  global events impacted polio eradication efforts, including how the CIA's 2011 fake vaccine campaign in Pakistan contributed to widespread vaccine mistrust.  She also will offer insights and recommendations for future efforts.
Dr. Ataullahjan is a professor, poet and researcher who studies public health issues as they relate to Pakistan, including this study on polio eradication efforts published in Expert Review of Vaccines. You can follow her on Twitter here. 

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In this episode of Causes or Cures, Dr. Eeks chats with author Susan Salenger about her book, SIDELINED, How Women Manage & Mismanage Their Health. Some of the topics covered in the book and on this podcast include why women put themselves second when it comes to health issues, why "nice girls finish last," the shame and blame game for when women are hit with an illness, a breakdown of communication when navigating the healthcare system, how pharmaceutical industries target women with their ads, the downside of the wellness industry and positive psychology, and an intriguing stroll through history to explain the context for why women mismanage their health. She will also provide tips on how women can better manage their health and even save their lives. You can learn more about Susan on her website.

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On this episode of Causes or Cures, Dr. Eeks chats with Professor Marianne Nissen Lund, who is a researcher and professor of food chemistry at the University of Copenhagen in Denmark. She will elaborate on what "food chemistry" means and how the chemical mechanisms in food and between foods can impact quality, stability and health. In this episode, she will focus on her recent work here and here and break down the chemistry into plain language to show how adding milk to coffee can increase its anti-inflammatory effects and lead to positive health outcomes. She will explain how they did the research, what they measured and describe the potential health benefits. A great one for coffee drinkers! ;)
(Photo Credit: Claus Boesen)


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