Health Via Modern Nutrition with Dr. Latt Mansor

Today, we have Robert Bent, founder of Inward, a global community to improve mental health. This episode is a wide-ranging one talking about “dark retreats,” silent meditations, and psychedelics & flow. Robert has a fascinating backstory of hedge funds, Ethereum Foundation and cryptocurrencies, and biohacking.

Inward Breathwork: https://www.inwardbreathwork.com/

Dark Retreat: https://robbiebent.substack.com/p/building-the-othership-episode-1

The Case For Vipassana: https://medium.com/@robbiebent/the-case-for-vipassana-3307abe12b1f

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Geoff and Latt are back for another research roundup!

Today, we dissect the paper by Yurista et al published in January 2021 which determines the effect of ketone ester supplementation in heart failure.

We discuss the paper’s methods and results which combines two different research groups using two different exogenous ketone esters in mice and rats.

So what's the verdict? Are ketones good for the heart?

Paper discussed:

Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure

https://pubmed.ncbi.nlm.nih.gov/33356362/

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Maintaining and optimizing brain and cognitive function is a key goal behind the H.V.M.N. community.

In this episode, Geoff brings on Dr. Dale Bredesen, a top researcher of neurodegenerative diseases to talk everything about cognitive health, cognitive decline, the fundamentals of Alzheimer’s disease, and a potential path to combat it**.**

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Geoff and Latt dissect the paper by McCarthy et al published in March 2021 which answers a key question from the previous research roundup: how to optimally dose ketone esters and is higher, always better?

They discuss the paper’s protocols, methods, results, and the athletes’ exogenous ketones dosing experience. What are the findings? Does it clarify the effect of dose-response effect of ketone supplementation on endurance performance and exercise responses?

Check out the previous research roundup here: Exogenous Ketone Oxidation Rates in Athletes - https://www.youtube.com/watch?v=A4B3Krxc3-g

Paper discussed:

Increased Cardiorespiratory Stress During Cycling After Ketone Monoester Ingestion Authors:

McCarthy, DG

Bostad, W

Powley, FJ

Little, JP

Richards, DL

Gibala, MJ

https://macsphere.mcmaster.ca/handle/11375/25548

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In this episode, Geoffrey Woo brings on Dr. Bret Scher the host of Diet Doctor podcast and a board-certified cardiologist and lipidologist in San Diego.

This is a wide-ranging conversation from Vegan vs. Keto diet, science research, advanced lipid testing, oxidized LDL, and the merits behind a “heart-healthy” seal.

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“True biohacking is not about gizmos and gadgets and the ability to spend money. It’s about a system and understanding of how to structure your sleep, your exercise, and your nutrition in a way that allows you to optimize toward your personal goals.”

-Geoffrey Woo

It’s really easy to make fun of Silicon Valley biohackers, so let’s do it.

In today’s Free Fatty Friday, Geoff pokes fun at biohackers as he breaks down the 3 core foundations in human performance and health:

1. Exercise
2. Nutrition
3. Sleep

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Twitter: @geoffreywoo

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Dr. Molly Maloof is back on the H.V.M.N. Podcast for Round 3.

Key topics discussed:

• Therapeutic potential and risks for psychedelics
• Types of meditation
• How meditation, flow state, and psychedelics are related
• Molly’s experience on state of samadhi
• Retrospective commentary on San Francisco / Silicon Valley community
• Nuances and application of fasting, especially for women

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In today’s Free Fatty Friday, Geoff breaks down the levels that people go through in their nutrition and diet journey. The whole point is to learn, understand, and master the rules, so you can ultimately make your diet work for you.

(0) Born defaults

(1) People who passively consume mainstream media about nutrition

(2) People who start going into food tribes

(3) Knowing and understanding the rules and principles so you can make diet work for you

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Geoff and Latt are back for another research roundup to unpack and discuss a new paper about the oxidation of exogenous ketones during exercise. How important are ketones as a fuel vs. a signaling molecule? How much ketones are enough for enhancing exercise performance? Is there such a thing as too much ketones?

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Dominic is an Associate Professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine. He is also a Research Scientist at the Institute for Human and Machine Cognition (IHMC).

And today, he’s back on the H.V.M.N. podcast to discuss the latest science on ketogenic diet and human metabolism.

Key point topics and studies mentioned:

• Ketogenic diets inhibit mitochondrial biogenesis and induce cardiac fibrosis -https://www.nature.com/articles/s41392-020-00411-4
• The falling heart utilizes 3-hydroxybutyrate as a metabolic stress defense - https://pubmed.ncbi.nlm.nih.gov/30668551/
• Metabolic Health Summit
• Exogenous Ketones
• Oxidized LDL
• Metabolic flexibility for Covid

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What is age? What is longevity?

There's two dominant ways in which we measure age — (1) chronological age, and (2) biological or epigenetic age. But in today’s Free Fatty Friday, Geoff introduces a new way to think about and measure age: cognitive flexibility.

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In today's Free Fatty Friday, Geoff talks about hope, optimism, and how no one in politics is talking a key lesson of COVID19: modernizing nutrition.

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Dr. Paul Mason obtained his medical degree with honors from the University of Sydney, and also holds degrees in Physiotherapy and Occupational Health. He is currently a Specialist Registrar in the Australasian College of Sports and Exercise Medicine.

Today, he joins HVMN podcast to unpack his learnings and observations from his clinical practice vs. the medical textbooks.

Some topics discussed:

• Minnesota Coronary Experiment
• Statins for diabetes
• Vegan diets to be deleterious
• 2004 study about saturated fat would increase LDL Oxidation
• Methods for measuring low-density lipoproteins
• Spiking of blood sugar and how that drives oxidative stress
• America’s dietary guidelines and modern food system

Follow Dr. Mason on: Twitter: https://twitter.com/DrPaulMason

Youtube: https://www.youtube.com/channel/UC3vzrYZcGqpgchc5sYM5Ybw

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“I want to help as many people in my short lifetime as I can.”

-Greg Taylor

He quit his job and decided to bike across America to raise funds as USA Cancer Cycle.

Starting February 20, 2021, he is now riding solo from Jacksonville to San Diego; San Diego to Seattle; Seattle to Maine; and Maine back to Jacksonville. His journey will be approximately 11,500 miles, and it’ll require smart planning, nutrition, and endurance.

In this episode, we chat nutrition (and how H.V.M.N. Keto Food Bar is a critical part of his nutrition), training, and the planning / logistics for a challenge like this.

The USA Cancer Cycle: https://www.usacancercycle.com

Follow them on Tiktok: https://www.tiktok.com/@usacancercycle

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I have officially moved to Miami, Florida! It's great so far and I break down my initial positive impressions into three categories: (1) Autophagy, (2) Novelty, and (3) Serendipity.

(3:55) 1. Autophagy - how to recycle and re-underwrite our schedule and our productivity.

(15:13) 2. Novelty - how to inject new stimuli to keep our minds and our attitude young and childlike.

(22:16) 3. Serendipity - how to maximize the random luck that physical interactions enable.

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Geoff and Dr. Latt Mansor discuss their new publication on ketones and post-exercise recovery and the inspiration behind the scholarship.

The ketogenic diet has been introduced in therapeutic areas for more than a century, but the role of ketones in exercise performance has only been explored in the past decade.

Do exogenous ketones work for post-exercise recovery? What are the current best practices and what are the potential mechanisms that drive improved recovery?

Paper PDF: https://www.frontiersin.org/articles/10.3389/fphys.2020.613648/full

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In this episode, we invite Cole Riley, the founder of Wellfare, a nonprofit food subscription service pioneering a modern approach to solve the nutrition crisis in America.

Geoff & Cole discuss:

• Wellfare’s background, vision and mission
• The hidden cost behind hyper-processed, shelf-stable consumer goods
• Healthy and bad snacking
• Food security for childhood development & poverty.
• How to solve the metabolic health crisis

We are super proud to be one of the earliest supporters and contributors to Wellfare!

Follow Cole on Twitter and Instagram here: @thecoleriley

Learn more about Wellfare here: http://wellfare.org

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“We should understand and embrace that our lives are not static, we got to be dynamic to truly self-actualize in the limited time we have on this planet.”

-Geoffrey Woo

I am moving to Miami! How I made the decision and why it’s so important to intentionally choose your environment.

2:08 (1) The importance of setting the environment.

8:40 (2) Always be the underdog.

15:45 (3) What am I going to be up to in Miami?

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In this episode, Geoffrey Woo brings on Stewart Alsop III, the host of the “Crazy Wisdom Podcast” and a Silicon Valley native who’s decamped to Brazil for the pandemic.

We explore geopolitics, groupthink, Stewart’s Covid-19 experience, movement practices, and proprioception.

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Watch this episode on Youtube: https://youtu.be/XW2eJGjQi8w

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Geoffrey Woo says “Life is too short to make all the mistakes yourself.” Geoff discusses best practices on (1) how to seek and receive advice, and (2) how to give advice.

3:30 - How to best seek and gain advice, how to qualify people before taking advice, and how to best implement advice.

17:27 - How to give advice, and considerations of high-signal, high-fidelity communication.

What is the best approach and framework to learn and take advice? Let’s discuss!

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