acute lymphoblastic leukemia

In this episode, Daniel J. DeAngelo, MD, PhD; Kjeld Schmiegelow, MD, DMSci; and Emily Curran, MD, answer key questions asked by the audience during a live satellite symposium at the 2022 American Society of Hematology Annual Meeting on optimizing pediatric or pediatric-inspired regimens containing asparaginase for the treatment of young and older adults with acute lymphoblastic leukemia.

Topics discussed include:

• Practical considerations for management of allergy-like reactions and hypersensitivity to asparaginase
• Indirect methods for measuring asparaginase activity
• Strategies to mitigate adverse events with asparaginase treatment, including hepatotoxicity, pancreatitis, and thrombosis
• Considerations for use of asparaginase in special populations (eg, high BMI, older age)

Presenters:

Program Director
Daniel J. DeAngelo, MD, PhD
Professor of Medicine
Department of Medicine
Harvard Medical School
Chief of the Division of Leukemia
Department of Medical Oncology
Division of Hematologic Malignancies
Dana‐Farber Cancer Institute
Boston, Massachusetts

Emily Curran, MD
Assistant Professor
Division of Hematology/Oncology
University of Cincinnati Cancer Institute
Cincinnati, Ohio

Kjeld Schmiegelow, MD, DMSci
Professor
Department of Pediatric Oncology
Righospitalet University Hospital
Copenhagen, Denmark

Content based on an online CME program supported by an independent educational grant from Jazz Pharmaceuticals.

Link to full program:
http://bit.ly/3YXkLyj

SHOW NOTES

4:35 – 35th wedding anniversary

5:25 – key qualities to a strong and meaningful relationship

6:00 – team approach

6:45 – facing unexpected fears, head on, one day at a time

7:25 – discovering inner strength

7:55 – Olivia, the amazing daughter and sister

9:05 – Special Love, Inc., Tom and Sheila Baker

9:35 ­– BRASS Camp

11:10 – Ryan, first cancer diagnosis at two years old

11:35 – ordinary family with an extraordinary circumstance

11:50 – leukemia meets it match with Ryan’s grit

15:00 ­– choosing hope is choosing life

15:15 – Make-a-Wish trips

16:15 – leading through advocacy

17:05 – management is key

17:45 – gratitude for such remarkable support – it kept us going, it keeps us going

19:25 – Camp Fantastic (Special Love, Inc.)

20:15 – no one wants to join the club of parents of children with cancer

21:00 – adult skills learned as a child through trial and error

23:30 – rhythm of life, impact on traditions, a roller coaster of life

24:35 – bringing home a puppy in the midst of the challenges

25:45 – ready to go to the hospital on a moment’s notice

27:10 – selecting quotations that capture the essence of one’s thoughts and intended message

29:05 – meeting Ryan’s bone marrow donor, Scott Harris

31:05 – consider joining the bone marrow registry

32:00 – graft versus host disease can be deadly

32:40 – Sharon and Lee Johnson, the ultimate role models and friends

35:15 – manufacturing sunshine

36:00 – Ryan’s loud pants

37:05 – writing a second book (Joyride Journeys)

38:30 – naming our cars and upcoming cross-country driving trip

39:20 – post-traumatic growth and gains

40:05 – how do we channel our loss?

41:40 – advocate for yourself

Focused Fight book

Ryan’s speech

Camp Fantastic

Bone Marrow Registry 

Terri’s website

Post-Traumatic Growth article

Music for Lead. Learn. Change. is Sweet Adrenaline by Delicate Beats

Podcast cover art is a view from Brunnkogel (mountaintop) over the mountains of the Salzkammergut in Austria, courtesy of photographer Simon Berger, published on www.unsplash.com.

Professional Association of Georgia Educators  

David’s LinkedIn page

Eight years following the death of her husband from acute lymphoblastic leukemia, Rachel reminisces on the love she lost and also the pain and lessons that came from his death as well.

Rachel found purpose through her pain in writing about her experience, which later became her book, and also through cancer advocacy.

In this episode, she shares the story of her husband's diagnosis and death two years later, as well as how she found her way to feeling better.

On top of the loss of her spouse, she would later have to come to terms with the fact that she will never have biological children and, also experienced a health setback herself, later being diagnosed with a disease of the colon.

RESOURCES:

• Ep. 40  | Dr. Chris Kerr 
• Wife, Widow, Now What?: How I Navigated the Cancer World and How You Can, Too

CONNECT:

• Instagram
• Facebook

______

Need help?

• National Suicide Prevention Lifeline: 1-800-273-8255
• Crisis Text Line provides free, 24/7 support via text message. Text HOME to 741741 to connect with a trained Crisis Counselor

If you or anyone you know is struggling with grief due to any of the 40+ losses, there are free resources available HERE.

Are you enjoying the podcast? Check out my bi-weekly newsletter, The Unleashed Letters.

💛Would you like to Learn Your Energy Type? Free Quiz ➡️HERE! ⬅️
______

SUPPORT THE SHOW:

• Rate & Review: Apple Podcasts
• Follow & Listen  Spotify |  Stitcher | Pandora
• Read & Review my published book about my grief journey.

CONNECT WITH VICTORIA: 

• Instagram
• Facebook

This episode is sponsored by Do Grief Differently™️, my twelve-week, one-on-one, in-person/online program for grievers who have suffered any type of loss to feel better. Click here to learn new tools, grief education, and the only evidence-based method for moving beyond the pain of grief.

Would you like to join the mission of Grieving Voices in normalizing grief and supporting hurting hearts everywhere? Become a supporter of the show HERE.

Leukemia & Lymphoma Society: https://www.lls.org/

Camp Quality USA: https://www.campqualityusa.org/

Camp Quality Michigan: https://www.campqualityusa.org/mi/

Make-A-Wish Foundation: https://wish.org/

Nathan Green, also known as Nate The Great, was first diagnosed with  Acute Lymphocytic Leukemia in 2011 at age 17. He was a junior in high school and battled for two and a half years before completing chemotherapy. 

This podcast was recorded in August 2019. Nate shares about life after receiving a cancer diagnosis and the journey that doesn't end when you hear the words "cancer free." He talks about walking through the journey as a young adult, dealing with the long term effects of chemo on the body, and his dreams for the future.

>> Nate is once again in the fight. On October 20, 2020, just over a year after this podcast was recorded, Nate heard what no leukemia survivor wants to hear, “the leukemia is back."

In this episode, David Marks, MD, PhD, and Stéphane de Botton, MD, answer questions from clinicians on management pearls for patients with acute leukemias. Topics include:

• MRD in the management of ALL
• Therapy choice for older patients with AML
• Optimal use of inotuzumab ozogamicin and blinatumomab for ALL
• Use of CAR T-cell therapy for acute leukemias

Content based on an online CME program supported by an educational grant from Pfizer Inc.

Link to full program:
https://bit.ly/3jiCBaD

Nothing has the potential of ruining our “perfect’ lives more than losing someone we love. Whether it’s a child, spouse, parent, significant other or friend - we all have those people in our lives that we can’t imagine living without. This episode is a raw and transparent look back to when Robin's worst nightmare came to life as her son was diagnosed and battled leukemia. No matter what the “cancer” is in your life, this conversation between Rachel and Robin can help you find hope in the midst of despair. 

Show Notes:

To watch the video Rachel created in 2018 about our cancer story:
https://www.thecrossingchurch.com/stories/matt-mays-story/

Want to connect with Robin and Rachel on Instagram? Find them here: https://instagram.com/theproblemwithperfect?igshid=9jvum57yip6l

Are you or someone you know battling cancer? Find more transparent stories and words of encouragement from the May Family's on Robin's blog at
https://bat-recorder-sznx.squarespace.com/config/pages

Need more information on navigating the blood cancer journey? Contact the Lymphoma and Leukemia Society at: https://www.lls.org/

Also connect with Robin on Facebook at Robin May Ministries
https://www.facebook.com/2330042033706535/posts/2871699789540754?sfns=mo or on Instagram at:  https://ww.instagram.com/p/B3lFRS8HELd/

Connect with Rachel and her life at the loft:
https://instagram.com/rachel__leigh__?igshid=1erbjftzgyje9

Or Email us your thoughts, questions or anything you want us to know at TheProblemWithPerfect@gmail.com

Casey Head, 3 time cancer survivor talks about her diagnosis with Acute lymphoblastic leukemia.  Diagnosed at the age of 31, Casey battled cancer 3 times with all kinds of chemotherapy and immunotherapy.  Casey discusses being hospitalized nearly 30 days straight and battling a stroke.

Reid Besch and I go a long way back...he was the older neighbor boy that played with my boys when they were little.

It's been 15 years since he was throwing footballs in our connected backyards.

In the last 2 years, he's been fighting for his life. 

He shares his story about being diagnosed with a rare form of cancer - Acute Lymphoblastic Leukemia (ALL) - and fighting to kill this disease out of his body. 

Since he was cleared of cancer, just a few short months ago, he's been asked to campaign for the Leukemia & Lymphoma Society Man of the Year Competition representing Tennessee! 

He shares all of this and more with me in our conversation. 

You're going to love it. 

And, should you feel led to support Reid, he has a donation link setup.