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    biosimilars

    Explore " biosimilars" with insightful episodes like "The Biopharma Buzz: Your Daily Dose of What Matters in Pharma and Biotech", "The State of Arthritis in Canada", "Rare Voices: Navigating Life with Uncommon Courage in Canada", "Drug development, review and public reimbursement in Canada" and "Biosimilars: Beyond the Switch with Dr.Carter Thorne PART 2" from podcasts like ""Pharma and BioTech Daily", "Arthritis At Home (+ On the Go)", "The Pharma Podcast", "Arthritis At Home (+ On the Go)" and "Skin and Joints Podcast"" and more!

    Episodes (41)

    The Biopharma Buzz: Your Daily Dose of What Matters in Pharma and Biotech

    The Biopharma Buzz: Your Daily Dose of What Matters in Pharma and Biotech
    Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.The biopharma industry is facing challenges with the rocky launch of Roctavian by Biomarin, as well as the departure of AbbVie CEO Richard Gonzalez. Frontier is making strides in developing a better KRAS drug with support from Galapagos. J&J has received EMA backing for earlier CAR-T use in multiple myeloma, and a NEJM paper explores a remarkable CAR-T result in autoimmune disease. Biosimilars are gaining traction in 2024 despite initial hurdles, reflecting an increase in market presence.Sanofi and Regeneron's Dupixent are undergoing a speedy FDA review for potential use in COPD, with a decision expected by June 27, 2024. AbbVie's success with Humira serves as a model for navigating the patent cliff, under the leadership of Richard Gonzalez. Frontier Medicines secures $80 million in Series C financing, while Blueprint's cancer drug Gavreto finds a new home at Rigel Pharmaceuticals. Bristol Myers Squibb is focusing on diverse therapeutic options for cancer treatment, leveraging advanced modalities. GSK ends its collaboration with Vir Biotechnology on anti-influenza antibodies, and Indian drugmakers explore the weight-loss market with new products. Yearlybird Health launches a $186 million venture capital fund.Despite recent staff cuts at companies like Galapagos, Adaptive, and Ring, the industry continues to offer job opportunities at companies like Amgen, Novo Nordisk, Kerecis, Life Edit, Emergent Biosolutions, and Moderna. Stay tuned for more updates on the latest developments in the biopharma industry.

    The State of Arthritis in Canada

    The State of Arthritis in Canada

    In this episode of Arthritis At Home, Cheryl Koehn, Founder and President, speaks to ACE’s VP Communications & Public Affairs, Kelly Lendvoy, about the highlights from the February 2024 issue of the JointHealth™ insight newsletter, including:

    • the newly published State of Arthritis in Canada Report Card
    • feature article on arthritis models of care gaps and solutions across northern communities in Canada
    • a look at biosimilars cost savings reinvestment in the healthcare system

    Additional learning resources

    Rare Voices: Navigating Life with Uncommon Courage in Canada

    Rare Voices: Navigating Life with Uncommon Courage in Canada

    On this special episode of the Pharma Podcast, we're honouring Rare Disease Month this February by delving into the personal and profound stories from the front lines of rare diseases in Canada. Our focus is on the unique challenges, healthcare experiences, and the resilience required to navigate life with a rare condition. In celebration of this important month, I’m thrilled to have Dr. Sonia Rehal with us. Sonia is not only courageously living with a rare disease but also actively participating in raising awareness and advocating for better support and research for rare diseases in Canada.

    Sonia's journey offers us a window into the day-to-day realities faced by individuals with rare diseases, from the quest for diagnosis to access to specialised care, and underscores the importance of community support. Her insights are invaluable in dispelling misconceptions about rare diseases and highlighting the ongoing efforts to improve the lives of those affected.

    Join us as we explore Sonia's story, the broader landscape of rare diseases in Canada, and what hope and advancements lie on the horizon for patients and their families. 

    Through this episode, we hope to convey a powerful message: while each rare disease may affect a small number of individuals, collectively, these conditions are not that rare at all. 

    Lipodystrophy Canada Website:

    https://lipodystrophy-canada-foundation.wiredwebsites.org/

     

    Facebook Page:

    https://www.facebook.com/profile.php?id=100092509705779

     

    Our Email address: 

    lipodystrophycanada@gmail.com



    Drug development, review and public reimbursement in Canada

    Drug development, review and public reimbursement in Canada

    In this episode, Kelly Lendvoy, VP Communications & Public Affairs speaks to ACE’s Founder and President, Cheryl Koehn, about the long and winding road towards drug development, review and public reimbursement in Canada. They discuss the highlights from a recently published JointHealth™ insight: the phases of drug development, the drug review process, price negotiations, and how it affects the lives of people living with inflammatory arthritis.

    Additional learning resources

    Biosimilars: Beyond the Switch with Dr.Carter Thorne PART 2

    Biosimilars: Beyond the Switch with Dr.Carter Thorne PART 2

    🎙️🌟 𝘽𝙞𝙤𝙨𝙞𝙢𝙞-𝙇𝙖𝙪𝙣𝙘𝙝: 𝘼 𝙏𝙖𝙡𝙚 𝙤𝙛 𝙎𝙠𝙞𝙣, 𝙅𝙤𝙞𝙣𝙩𝙨 𝙖𝙣𝙙 𝘽𝙤𝙡𝙙 𝘽𝙚𝙜𝙞𝙣𝙣𝙞𝙣𝙜𝙨 PART 2! 🌟🎙️

    🚀#𝗢𝗻𝘁𝗮𝗿𝗶𝗼 𝗵𝗮𝘀 𝘁𝗮𝗸𝗲𝗻 𝗮 𝗺𝗮𝗷𝗼𝗿 𝘀𝘁𝗲𝗽 𝗳𝗼𝗿𝘄𝗮𝗿𝗱 𝗶𝗻 𝘁𝗵𝗲 𝘄𝗼𝗿𝗹𝗱 𝗼𝗳 #𝗯𝗶𝗼𝘀𝗶𝗺𝗶𝗹𝗮𝗿 𝘁𝗵𝗲𝗿𝗮𝗽𝗶𝗲𝘀 𝘄𝗶𝘁𝗵 𝘁𝗵𝗲 𝘀𝘁𝗮𝗿𝘁 𝗼𝗳 𝘁𝗵𝗲𝗶𝗿 𝘁𝗿𝗮𝗻𝘀𝗶𝘁𝗶𝗼𝗻 𝗽𝗲𝗿𝗶𝗼𝗱 & 𝘄𝗲'𝘃𝗲 𝗴𝗼𝘁 𝘁𝗵𝗲 𝗶𝗻𝘀𝗶𝗱𝗲 𝘀𝗰𝗼𝗼𝗽!

    𝗢𝗻𝘁𝗮𝗿𝗶𝗼 𝗯𝗮𝘀𝗲𝗱 #rheumatologist, 𝗗𝗿.Carter Thorne 𝗹𝗼𝗼𝗸s 𝗶𝗻𝘁𝗼 𝘁𝗵𝗲 𝗳𝗮𝘀𝗰𝗶𝗻𝗮𝘁𝗶𝗻𝗴 𝘄𝗼𝗿𝗹𝗱 𝗼𝗳 𝗿𝗲𝗮𝗹-𝘄𝗼𝗿𝗹𝗱 𝗲𝘃𝗶𝗱𝗲𝗻𝗰𝗲 (RWE) 𝗳𝗼𝗿 𝗯𝗶𝗼𝘀𝗶𝗺𝗶𝗹𝗮𝗿 𝘁𝗵𝗲𝗿𝗮𝗽𝗶𝗲𝘀💉🔍𝗲𝗺𝗲𝗿𝗴𝗶𝗻𝗴 𝗥𝗪𝗘 transition 𝗱𝗮𝘁𝗮 𝘁𝗿𝗲𝗻𝗱𝘀, 𝗮𝗻𝗱 𝘁𝗵𝗲 𝘃𝗮𝗹𝘂𝗲 𝗶𝘁 𝗰𝗮𝗻 𝗵𝗮𝘃𝗲 𝗼𝗻 𝗷𝗼𝗶𝗻𝘁 & 𝘀𝗸𝗶𝗻 𝘁𝗿𝗲𝗮𝘁𝗺𝗲𝗻𝘁 𝗺𝗮𝗻𝗮𝗴𝗲𝗺𝗲𝗻𝘁 𝗱𝗲𝗰𝗶𝘀𝗶𝗼𝗻𝘀! 💪🤓
    𝗙𝗶𝗻𝗱 𝗼𝘂𝘁 𝗵𝗼𝘄 𝘁𝗼 𝗯𝗲 𝗮 #𝗯𝗶𝗼𝘀𝗶𝗺𝗶𝗹𝗮𝗿 wizard 💼🏆 𝘄𝗶𝘁𝗵 𝗼𝘂𝗿 𝗲𝘀𝘀𝗲𝗻𝘁𝗶𝗮𝗹 𝗴𝘂𝗶𝗱𝗲 𝘁𝗼 𝗻𝗮𝘃𝗶𝗴𝗮𝘁𝗶𝗻𝗴 𝘁𝗵𝗶𝘀 𝗻𝗲𝘄 𝘁𝗲𝗿𝗿𝗮𝗶𝗻 𝗶𝗻 𝘆𝗼𝘂𝗿 𝗱𝗮𝘆-𝘁𝗼-𝗱𝗮𝘆 𝗽𝗿𝗮𝗰𝘁𝗶𝗰𝗲 🗺️👩‍⚕️👨‍⚕️

    👨‍⚕️Dr.Thorne 𝙞𝙨 𝙞𝙣𝙫𝙤𝙡𝙫𝙚𝙙 𝙞𝙣 𝘾𝘼𝙏𝘾𝙃 (𝘾𝙖𝙣𝙖𝙙𝙞𝙖𝙣 𝙀𝙖𝙧𝙡𝙮 𝘼𝙧𝙩𝙝𝙧𝙞𝙩𝙞𝙨 𝘾𝙤𝙝𝙤𝙧𝙩), 𝙊𝘽𝙍𝙄 (𝙊𝙣𝙩𝙖𝙧𝙞𝙤 𝘽𝙚𝙨𝙩 𝙋𝙧𝙖𝙘𝙩𝙞𝙘𝙚𝙨 𝙍𝙚𝙨𝙚𝙖𝙧𝙘𝙝 𝙄𝙣𝙞𝙩𝙞𝙖𝙩𝙞𝙫𝙚) 𝙖𝙣𝙙 𝙖𝙩 𝙡𝙤𝙘𝙖𝙡, 𝙥𝙧𝙤𝙫𝙞𝙣𝙘𝙞𝙖𝙡 𝙖𝙣𝙙 𝙣𝙖𝙩𝙞𝙤𝙣𝙖𝙡 𝙢𝙤𝙙𝙚𝙡𝙨 𝙤𝙛 𝙘𝙖𝙧𝙚 𝙞𝙣𝙞𝙩𝙞𝙖𝙩𝙞𝙫𝙚𝙨.
     

    🎧 🎉Dr. Thorne is an Assistant Professor at the University of Toronto, and is on the Consultant Staff at Southlake Regional Health Centre in Newmarket, Ontario where he was Chief of the Division of Rheumatology and Director of The Arthritis Program; the latter is a unique Inter-Professional care program established to optimize outcomes for people who have arthritis and other rheumatic disorders. He is sought for his expertise in developing Outcome Based clinical Programs, not only in Arthritis Care, but also Shared Care in a Comprehensive Musculoskeletal Program, Wound Management and NeuroRehab/Stroke Care.

     

    He is active in Clinical Research as Principal Investigator with The Arthritis Program Research Group Inc. As part of a strategic interest in identifying ‘Best Practices’, he has established an Early Arthritis Clinic, collaborating with a national initiative, CATCH -of which he is a member of the Scientific Advisory Committee and Operations Director, and an Osteoporosis Intervention Clinic. He sits on the Steering and Scientific Committee of the Ontario Best Practices Research Initiative, a collaborative attempt among stakeholders to describe and disseminate outcomes and best practices, in the management of Rheumatoid Arthritis. He was an active Investigator and participant in the successful Canadian Rheumatology Research Consortium and served as Secretary-Treasurer, until its conclusion in 2014. He is a founding member of the Ontario Rheumatology Association and Past-President (2006-10). He is past President of the Canadian Rheumatology Association (2012-2014) and past Secretary-Treasurer (1996-2004). He is past Secretary-Treasurer of PANLAR, and has served on the Steering Committee of CARE, a European-based group interested in the non-pharmacologic management of arthritis. He was a member of the Rehab Committee of the American College of Rheumatology 2003-09 and served as Chair pf the Committee, till its dissolution.

     

    He has been involved in improving care for those with arthritis through the above initiatives, and his work with CRA and ORA, in Best Practices identification and dissemination strategies, and development of Models of Care frameworks (ORA); and improving the health of the community, as a past member of the York Region District Health Council (DHC) and past-Chair of the amalgamated Simcoe-York DHC. Since the recent cancellation of TAP by Southlake, he has become energized in the establishment of a Not-for-Profit organization (Centre of Arthritis Excellence - CArE) to develop a community-based MSK program, the first of its kind supported by the Ontario Ministry of Health, as a Portal of MSK Care, utilizing an Inter-Professional MoC, opening September 2022.

     

    Dr. Thorne has been recognized by his colleagues and peers, with the ORA Distinguished Rheumatologist Award (2010), the CRA Distinguished Rheumatologist Award (2015), and the Queen Elizabeth II Diamond Jubilee Medal (2012), and has been recognized as a Master of the American College of Rheumatology (2016), in Washington DC. And awarded Master CRA in

     

    Episode Learning Objectives

     

     

    In this podcast episode, we will explore the value of Real-World Evidence (RWE) in biosimilars for daily clinical practice decisions. Our discussion will be divided into two parts: the first part will focus on RWE, and the second part will center on the biosimilar switch experience.

     

    By the end of this episode, listeners should be able to:

    • Understand the concept of Real-World Evidence (RWE) in the biosimilar space and its significance for healthcare professionals.
    • Recognize the benefits and advantages of RWE, such as switch data and varying patient demographics.
    • Analyze the impact of RWE on therapeutic decision-making for inflammatory joint management.
    • Differentiate between various types of RWE in the biosimilar space (e.g., registry CATCH cohort, data based on patient records, health economic research) and evaluate their credibility and methodology.
    • Discuss the future of TNFA-i and RWE in clinical practice.
    • Identify factors to consider when differentiating between biosimilars during a switch.
    • Address potential pain points during the biosimilar switch process, such as managing patient expectations, mitigating the nocebo effect, and navigating access.
    • Share insights and strategies for healthcare professionals to approach the biosimilar switch process effectively in their clinic and practice workflow

    Biosimilars and the Problem with PBMs: Interview with Juliana M. Reed, Executive Director of the Biosimilars Forum

    Biosimilars and the Problem with PBMs: Interview with Juliana M. Reed, Executive Director of the Biosimilars Forum

    Uptake of biosimilars is lagging in the US, but why? In this episode, Sarah interviews Juliana M. Reed, Executive Director of the Biosimilars Forum, to find out the real barriers to widespread access to biosimilars, and how these problems could be addressed.

    Julie discusses the role of pharmacy benefit managers (PBMs) and the incentives that keep them from listing most biosimilars on their formularies. She applauds the recent launch of multiple new biosimilars for the blockbuster biologic Humira and explains why this moment is pivotal for the biosimilars industry and the US healthcare system as a whole. 

    Mentioned during this episode:

    Interview with Dr. Gillian Woollett, VP, Head of Regulatory Strategy and Policy at Samsung Bioepis – Xtalks Life Science Podcast Ep. 110

    For more life science and medical device content, visit the Xtalks Vitals homepage.

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    Biosimilars: Beyond the Switch with Dr.Carter Thorne PART 1

    Biosimilars: Beyond the Switch with Dr.Carter Thorne PART 1

    🎙️🌟 𝘽𝙞𝙤𝙨𝙞𝙢𝙞-𝙇𝙖𝙪𝙣𝙘𝙝: 𝘼 𝙏𝙖𝙡𝙚 𝙤𝙛 𝙎𝙠𝙞𝙣, 𝙅𝙤𝙞𝙣𝙩𝙨 𝙖𝙣𝙙 𝘽𝙤𝙡𝙙 𝘽𝙚𝙜𝙞𝙣𝙣𝙞𝙣𝙜𝙨! 🌟🎙️

    🚀#𝗢𝗻𝘁𝗮𝗿𝗶𝗼 𝗵𝗮𝘀 𝘁𝗮𝗸𝗲𝗻 𝗮 𝗺𝗮𝗷𝗼𝗿 𝘀𝘁𝗲𝗽 𝗳𝗼𝗿𝘄𝗮𝗿𝗱 𝗶𝗻 𝘁𝗵𝗲 𝘄𝗼𝗿𝗹𝗱 𝗼𝗳 #𝗯𝗶𝗼𝘀𝗶𝗺𝗶𝗹𝗮𝗿 𝘁𝗵𝗲𝗿𝗮𝗽𝗶𝗲𝘀 𝘄𝗶𝘁𝗵 𝘁𝗵𝗲 𝘀𝘁𝗮𝗿𝘁 𝗼𝗳 𝘁𝗵𝗲𝗶𝗿 𝘁𝗿𝗮𝗻𝘀𝗶𝘁𝗶𝗼𝗻 𝗽𝗲𝗿𝗶𝗼𝗱 & 𝘄𝗲'𝘃𝗲 𝗴𝗼𝘁 𝘁𝗵𝗲 𝗶𝗻𝘀𝗶𝗱𝗲 𝘀𝗰𝗼𝗼𝗽!

    𝗢𝗻𝘁𝗮𝗿𝗶𝗼 𝗯𝗮𝘀𝗲𝗱 #rheumatologist, 𝗗𝗿.Carter Thorne 𝗹𝗼𝗼𝗸s 𝗶𝗻𝘁𝗼 𝘁𝗵𝗲 𝗳𝗮𝘀𝗰𝗶𝗻𝗮𝘁𝗶𝗻𝗴 𝘄𝗼𝗿𝗹𝗱 𝗼𝗳 𝗿𝗲𝗮𝗹-𝘄𝗼𝗿𝗹𝗱 𝗲𝘃𝗶𝗱𝗲𝗻𝗰𝗲 (RWE) 𝗳𝗼𝗿 𝗯𝗶𝗼𝘀𝗶𝗺𝗶𝗹𝗮𝗿 𝘁𝗵𝗲𝗿𝗮𝗽𝗶𝗲𝘀💉🔍𝗲𝗺𝗲𝗿𝗴𝗶𝗻𝗴 𝗥𝗪𝗘 transition 𝗱𝗮𝘁𝗮 𝘁𝗿𝗲𝗻𝗱𝘀, 𝗮𝗻𝗱 𝘁𝗵𝗲 𝘃𝗮𝗹𝘂𝗲 𝗶𝘁 𝗰𝗮𝗻 𝗵𝗮𝘃𝗲 𝗼𝗻 𝗷𝗼𝗶𝗻𝘁 & 𝘀𝗸𝗶𝗻 𝘁𝗿𝗲𝗮𝘁𝗺𝗲𝗻𝘁 𝗺𝗮𝗻𝗮𝗴𝗲𝗺𝗲𝗻𝘁 𝗱𝗲𝗰𝗶𝘀𝗶𝗼𝗻𝘀! 💪🤓
    𝗙𝗶𝗻𝗱 𝗼𝘂𝘁 𝗵𝗼𝘄 𝘁𝗼 𝗯𝗲 𝗮 #𝗯𝗶𝗼𝘀𝗶𝗺𝗶𝗹𝗮𝗿 wizard 💼🏆 𝘄𝗶𝘁𝗵 𝗼𝘂𝗿 𝗲𝘀𝘀𝗲𝗻𝘁𝗶𝗮𝗹 𝗴𝘂𝗶𝗱𝗲 𝘁𝗼 𝗻𝗮𝘃𝗶𝗴𝗮𝘁𝗶𝗻𝗴 𝘁𝗵𝗶𝘀 𝗻𝗲𝘄 𝘁𝗲𝗿𝗿𝗮𝗶𝗻 𝗶𝗻 𝘆𝗼𝘂𝗿 𝗱𝗮𝘆-𝘁𝗼-𝗱𝗮𝘆 𝗽𝗿𝗮𝗰𝘁𝗶𝗰𝗲 🗺️👩‍⚕️👨‍⚕️

    👨‍⚕️Dr.Thorne 𝙞𝙨 𝙞𝙣𝙫𝙤𝙡𝙫𝙚𝙙 𝙞𝙣 𝘾𝘼𝙏𝘾𝙃 (𝘾𝙖𝙣𝙖𝙙𝙞𝙖𝙣 𝙀𝙖𝙧𝙡𝙮 𝘼𝙧𝙩𝙝𝙧𝙞𝙩𝙞𝙨 𝘾𝙤𝙝𝙤𝙧𝙩), 𝙊𝘽𝙍𝙄 (𝙊𝙣𝙩𝙖𝙧𝙞𝙤 𝘽𝙚𝙨𝙩 𝙋𝙧𝙖𝙘𝙩𝙞𝙘𝙚𝙨 𝙍𝙚𝙨𝙚𝙖𝙧𝙘𝙝 𝙄𝙣𝙞𝙩𝙞𝙖𝙩𝙞𝙫𝙚) 𝙖𝙣𝙙 𝙖𝙩 𝙡𝙤𝙘𝙖𝙡, 𝙥𝙧𝙤𝙫𝙞𝙣𝙘𝙞𝙖𝙡 𝙖𝙣𝙙 𝙣𝙖𝙩𝙞𝙤𝙣𝙖𝙡 𝙢𝙤𝙙𝙚𝙡𝙨 𝙤𝙛 𝙘𝙖𝙧𝙚 𝙞𝙣𝙞𝙩𝙞𝙖𝙩𝙞𝙫𝙚𝙨.
     

    🎧 🎉Dr. Thorne is an Assistant Professor at the University of Toronto, and is on the Consultant Staff at Southlake Regional Health Centre in Newmarket, Ontario where he was Chief of the Division of Rheumatology and Director of The Arthritis Program; the latter is a unique Inter-Professional care program established to optimize outcomes for people who have arthritis and other rheumatic disorders. He is sought for his expertise in developing Outcome Based clinical Programs, not only in Arthritis Care, but also Shared Care in a Comprehensive Musculoskeletal Program, Wound Management and NeuroRehab/Stroke Care.

     

    He is active in Clinical Research as Principal Investigator with The Arthritis Program Research Group Inc. As part of a strategic interest in identifying ‘Best Practices’, he has established an Early Arthritis Clinic, collaborating with a national initiative, CATCH of which he is a member of the Scientific Advisory Committee and Operations Director, and an Osteoporosis Intervention Clinic. He sits on the Steering and Scientific Committee of the Ontario Best Practices Research Initiative, a collaborative attempt among stakeholders to describe and disseminate outcomes and best practices, in the management of Rheumatoid Arthritis. He was an active Investigator and participant in the successful Canadian Rheumatology Research Consortium and served as Secretary-Treasurer, until its conclusion in 2014. He is a founding member of the Ontario Rheumatology Association and Past-President (2006-10). He is past President of the Canadian Rheumatology Association (2012-2014) and past Secretary-Treasurer (1996-2004). He is past Secretary-Treasurer of PANLAR, and has served on the Steering Committee of CARE, a European-based group interested in the non-pharmacologic management of arthritis. He was a member of the Rehab Committee of the American College of Rheumatology 2003-09 and served as Chair pf the Committee, till its dissolution.

     

    He has been involved in improving care for those with arthritis through the above initiatives, and his work with CRA and ORA, in Best Practices identification and dissemination strategies, and development of Models of Care frameworks (ORA); and improving the health of the community, as a past member of the York Region District Health Council (DHC) and past-Chair of the amalgamated Simcoe-York DHC. Since the recent cancellation of TAP by Southlake, he has become energized in the establishment of a Not-for-Profit organization (Centre of Arthritis Excellence - CArE) to develop a community-based MSK program, the first of its kind supported by the Ontario Ministry of Health, as a Portal of MSK Care, utilizing an Inter-Professional MoC, opening September 2022.

     

    Dr. Thorne has been recognized by his colleagues and peers, with the ORA Distinguished Rheumatologist Award (2010), the CRA Distinguished Rheumatologist Award (2015), and the Queen Elizabeth II Diamond Jubilee Medal (2012), and has been recognized as a Master of the American College of Rheumatology (2016), in Washington DC. 

     

    Episode Learning Objectives

     

     

    In this podcast episode, we will explore the value of Real-World Evidence (RWE) in biosimilars for daily clinical practice decisions. Our discussion will be divided into two parts: the first part will focus on RWE, and the second part will center on the biosimilar switch experience.

     

    By the end of this episode, listeners should be able to:

    • Understand the concept of Real-World Evidence (RWE) in the biosimilar space and its significance for healthcare professionals.
    • Recognize the benefits and advantages of RWE, such as switch data and varying patient demographics.
    • Analyze the impact of RWE on therapeutic decision-making for inflammatory joint management.
    • Differentiate between various types of RWE in the biosimilar space (e.g., registry CATCH cohort, data based on patient records, health economic research) and evaluate their credibility and methodology.
    • Discuss the future of TNFA-i and RWE in clinical practice.
    • Identify factors to consider when differentiating between biosimilars during a switch.
    • Address potential pain points during the biosimilar switch process, such as managing patient expectations, mitigating the nocebo effect, and navigating access.
    • Share insights and strategies for healthcare professionals to approach the biosimilar switch process effectively in their clinic and practice workflow

    Ukraine - Starting and Running a Business in Difficult Circumstances

    Ukraine - Starting and Running a Business in Difficult Circumstances

    On this episode of the PharmaPodcast, I have an extra special guest. Artem Brytchenko is CEO at Platforce, a company based in Ukraine that he continues to run, in spite of all the adversity he is facing during a time of war.  I’m sure you will find this interview not just informative, but also Inspirational.

    Contact Information:

    Artem Brytchenko 

    Chief Executive Officer | Platforce

    E:  support@platforce.io

    W: https://platforce.io/

    Dr. Durhane Wong-Rieger - Bringing awareness to Rare Disease Day

    Dr. Durhane Wong-Rieger - Bringing awareness to Rare Disease Day

    On this episode of the Pharma Podcast, my extra-special guest is Dr. Durhane Wong-Rieger,  President & CEO at Canadian Organization for Rare Disorders.

    To mark Rare Disease Day, which we celebrate on the last day of February, I can think of no better guest than Dr. Durhane Wong-Rieger to bring awareness to Rare Disease Day.

    She also gives a great overview of CORD and its mission.

    To learn more about CORD, upcoming events, or to make a donation, please visit: www.raredisorders.ca

    You can also follow CORD on social media:

    https://www.facebook.com/RareDisorders

    https://twitter.com/raredisorders

    https://www.youtube.com/user/CORDRareDisorders





     

    Amgen Launches Humira Biosimilar Amjevita + Potential New Blood Test for Early Detection of Alzheimer's

    Amgen Launches Humira Biosimilar Amjevita + Potential New Blood Test for Early Detection of Alzheimer's

    In this episode, Ayesha talked about the launch of Amgen’s Amjevita, the first Humira biosimilar to hit the market. Amjevita received FDA approval in 2016 and after a legal settlement with Humira maker AbbVie, has finally reached market launch. AbbVie has been embroiled in legal battles over accusations of overpatenting and price hiking to block Humira biosimilar competition. Hear more about Amjevita and how 2023 is a big year for Humira biosimilars with over half a dozen more launching this year.

    Ayesha also discussed new Alzheimer’s research from Kings College London that could lead to the development of a blood test for the early detection of the disease. The research found that certain biomarkers in the blood of patients with mild cognitive impairment (MCI), which some Alzheimer’s patients develop before being diagnosed with the disease, could predict the onset of Alzheimer’s up to 3.5 years before a clinical diagnosis is made. Learn more about the new research in this episode.

    Read the full articles here:

    Amgen’s Amjevita Enters Market as First Humira Biosimilar, But at Two Different Price Points

    Early Detection of Alzheimer’s Disease: New Research Shows How a Blood Test Could Lead to Earlier Diagnosis

    For more life science and medical device content, visit the Xtalks Vitals homepage.

    Follow Us on Social Media

    Twitter: @Xtalks
    Instagram: @Xtalks
    Facebook: https://www.facebook.com/Xtalks.Webinars/
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    YouTube: https://www.youtube.com/c/XtalksWebinars/featured 

    The NEAR Future of Regenerative medicine

    The NEAR Future of Regenerative medicine

    On this episode of the Pharma Podcast, my guest is  Dr, Drew Taylor, founder and CEO of ACORN BIOLABS.

    As an entrepreneur and regenerative medicine pioneer, Drew is making breakthrough medicine accessible for everyday people. After simultaneously earning a PhD in Biomedical Engineering at the University of Toronto and playing professional baseball, Drew worked as part of Mount Sinai Hospital’s Bio-engineering of Skeletal Tissues Team, then as Chief Science Officer at Epic Capital Management. 

    In 2017, Drew co-founded Acorn Biolabs, to help more people access the future of regenerative medicine by providing affordable, accessible, and non-invasive cell banking.


    Drew and I discuss his journey to entrepreneurship, and the NEAR FUTURE of Regenerative medicine.


    Contact Information:

    Drew Taylor, MSc, PhD

    Chief Executive Officer | Acorn Biolabs Inc.

    E: info@acorn.me

    W: acorn.me
    Instagram:
    @drdrewtaylor

    Save your cells from aging.
    Join our waitlist | Sign-up for the newsletter

    Episode 68: Biosimilars 101 & Inflammatory Arthritis

    Episode 68: Biosimilars 101 & Inflammatory Arthritis
    Access will soon expand for new biologic treatments for inflammatory arthritis called biosimilars. Learn what they are, what to expect when taking one, including safety and effectiveness, and how determine if they are right for you. Visit the Live Yes! With Arthritis Podcast episode page get show notes, additional resources and read the full transcript: https://www.arthritis.org/liveyes/podcast/new-podcast/ep68-biosimilars-101-inflammatory-arthritis We want to hear from you. Tell us what you think about the Live Yes! With Arthritis Podcast. Get started by emailing podcast@arthritis.org. Special Guest: Mark S. Box, MD, FACR, FACP.

    CPOINT CAPITAL - How a Changing Economy is Affecting Investor Appetites

    CPOINT CAPITAL - How a Changing Economy is Affecting Investor Appetites

    Welcome to the Pharma Podcast, conversations with industry experts and business leaders about important and current topics in Canadian pharma, biotech and medtech.

    On this episode of the PharmaPodcast, my guest is  Jesse Buckstein, Principle at CPoint Capital

    Jesse and I discuss the Healthcare investment market in Canada - How a changing economy is affecting investor appetites.


    Contact Information for Jesse:

    CPOINT Capital
    512-555 Richmond Street West, Toronto, ON, M5V 3B1
    T: +1 905 881 4440 x 203 | M: +1 647 981 4293 | F: +1 647 847 9055
    E: jesse@cpointcapital.ca | W: www.cpointcapital.com

    Biosimilar Series: Part 1

    Biosimilar Series: Part 1

    In this episode, the first of our biosimilar education series, Kathy Oubre, CEO of Pontchartrain Cancer Center, and Neil Udovich, Vice President of Sales for AmerisourceBergen Specialty GPOs, discuss what biosimilars are (and aren’t), interchangeability with their reference products, and Kathy’s experience with adopting them into her practice.

    If you have any questions for our guests or have a topic you would like to learn more about, email us at OnCallGPO@gmail.com

    Bloom Burton - Healthcare Investment Market in Canada

    Bloom Burton - Healthcare Investment Market in Canada

    Welcome to the Pharma Podcast, conversations with industry experts and business leaders about important and current topics in Canadian pharma, biotech and medtech.

    On this episode of the PharmaPodcast, my guest is Brian Bloom, CEO, Bloom Burton

    On the heels of the Bloom Burton Healthcare Investor Conference, which was held in Toronto on May 2-3, Brian and I will discuss the latest developments in Canadian healthcare companies.

    Contact Information for Bloom Burton:
    reception@bloomburton.com
    https://www.bloomburton.com/contact-us/

    Keren Haruvi - President, Sandoz US, Head Of North America - Global Generic Medicine Access For All

    Keren Haruvi - President, Sandoz US, Head Of North America - Global Generic Medicine Access For All

    Keren Haruvi is President of Sandoz US and Head of their North America business (https://www.novartis.us/about-us/our-leadership/us-country-leadership/keren-haruvi). Sandoz is a division of the Novartis Group and a global leader in generic pharmaceuticals and biosimilars and was established in 2003, when Novartis united all of its generics businesses under the name Sandoz – a single global brand with a long history. Since then, Sandoz has grown into a leading global generics business with annual sales of approximately US$10 billion. In her current role, Keren leads Sandoz’ largest commercial and country organization – the United States – which is responsible for over 35% of Sandoz global revenue. She also oversees Sandoz commercial operations in Canada. In addition to serving on the Novartis Country Leadership Team, Keren is a member of the Global Sandoz Executive Committee. Prior to joining Sandoz, Keren served as Global Head of M&A at Novartis International AG. Her early career began at Teva Pharmaceutical Industries where she steadily advanced in leadership roles to Senior VP, Global Business Development and Alliance Management. Keren is a value creator in the biopharmaceutical space, and brings close to 20 years of experience in the pharmaceutical industry, marked by success leading major M&A deals, enterprise innovations, and complex market strategies for large-scale, sustainable growth. Keren holds an MBA in Finance from Bar Ilan University and a Bachelor’s degrees in Economics and Chemistry from Tel Aviv University. Nominated for Top 40 Under 40 in The Marker magazine, she exemplifies the insight and wisdom needed to move global organizations forward. Outside of work, Keren enjoys spending time with her 5 children. She is an avid runner with one marathon and 3 half-marathons under her belt.

    Support the show

    The Benefits of Biosimilar Drugs

    The Benefits of Biosimilar Drugs

    The use of biosimilar drugs – which mimic existing biologic drugs – could reduce U.S. drug costs by more than $100 billion over the next five years. However, there are still challenges in getting these lower-cost medications into the hands of patients. Savitha Vivian, Senior Vice President, Clinical and Formulary Services at Optum Rx, discusses the pipeline of biosimilar drugs – including a highly-anticipated 2023 launch – and how broader use of biosimilars could improve prescription drug affordability for patients.

    FDA Approves Interchangeable Humira Biosimilar + Gene Silencing Treatment for Porphyria Gets Nod From England's NICE

    FDA Approves Interchangeable Humira Biosimilar + Gene Silencing Treatment for Porphyria Gets Nod From England's NICE

    In this episode, the editorial team discusses the FDA approval of Cyltezo as the first interchangeable biosimilar for AbbVie’s Humira. The approval lends to the growing Humira biosimilars market, which will take off in 2023 with Boehringer Ingelheim’s Cyltezo and biosimilars from Amgen, Merck and Alvotech. AbbVie has been facing a lot of heat over accusations of price gouging and patent abuses to block Humira biosimilars from entering the market. The team had an interesting discussion about public perceptions of generics and biosimilars versus their originals/reference products.

    Ayesha also talked about a new gene silencing treatment for porphyria called Givlaari that received recommendation from England’s NICE after having been initially rejected by the health watchdog last year. Additionally, long-term results from a late-stage trial for Givlaari were recently released, which showed that the treatment provides sustained benefit and has a good safety profile. However, the team discussed the high cost of the treatment, which is a concern for patients in countries that don’t have some form of socialized healthcare.

    Read the full articles here: 

    Cyltezo Becomes First FDA-Approved Interchangeable Humira Biosimilar 

    Gene Silencing Porphyria Treatment, Givlaari, Finally Wins Over England’s NICE Amid Stellar Long-Term Data 

    For more life science and medical device content, visit the Xtalks Vitals homepage.

    Follow Us on Social Media

    Twitter: @Xtalks
    Instagram: @Xtalks
    Facebook: https://www.facebook.com/Xtalks.Webinars/
    LinkedIn: https://www.linkedin.com/company/xtalks-webconferences
    YouTube: https://www.youtube.com/c/XtalksWebinars/featured

    James Robinson On The Drug Market, Innovation, Biosimilars, and What The French Get Right

    James Robinson On The Drug Market, Innovation, Biosimilars, and What The French Get Right

    Learn more about academic opportunities in Health Policy and Law at UCSF and UC Law San Francisco.


    In our multi-payer health care system, the pharmaceutical market involves the complex interplay of manufacturers, insurers, prescribers, and patients. Each seeks to protect its own interest, which can be counterproductive for overall system efficiency.

    The United States also has a high rate of generic drug use, which is considered a success story as the introduction of generics can rapidly and dramatically reduce drug prices. But we've had much less success with biosimilars, the generic equivalent of high-cost biologic drugs.

    James Robinson from the University of California, Berkeley School of Public Health joins A Health Podyssey to discuss pharmaceuticals, how they're priced, and how competition in the United States compares to other countries.

    Robinson is a contributing editor to Health Affairs and the co-author of two papers published in the August 2021 issue. In one, Robinson and coauthor Quentin Jarrion analyze prices for three drugs and 11 competing biosimilars in France's single payer health system. They find the launch of biosimilars in France is associated with price reductions for the originator drug and the similar drug.

    In the second paper, Robinson and coauthors investigated the economic burden of drug utilization management on payers, manufacturers, physicians, and patients. They report that all stakeholders would benefit from a de-escalation of utilization management, which could lower drug prices and increase patient access.

    Order the August 2021 issue.

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    Build vs. Buy Pendulum: Should CROs buy technology capabilities or should they develop them in-house?”

    Build vs. Buy Pendulum: Should CROs buy technology capabilities or should they develop them in-house?”

    On this episode of The Pharma Podcast, my guest is Raj Indupuri, CEO, eClinical Solutions. 

    Raj  and I explore the Build vs. Buy Pendulum: Should CROs buy technology capabilities or should they develop them in-house?” 

    Contact Information:
    Raj Indupuri
    CEO
    eClinical Solutions
    rindupuri@eclinicalsol.com
    tel. 508.594.6313


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