metastatic cancer

This episode features an interview with Carlos Doti, MD, Vice President, US Medical Affairs Oncology, AstraZeneca, about new breast cancer treatments.

Dr. Doti is a hematologist by training and is passionate about developing treatments that have a real impact for people living with cancer across every aspect of their disease. Dr. Doti has worked in industry for the last 14 years, including seven years at AstraZeneca in various roles, and in small markets like Argentina as well as larger global markets. Since 2022, Dr. Doti has been focusing on the US market in hematology and oncology, working in breast, lung, GI and gynecological cancers among others.

Dr. Doti has previously served in medical affairs roles at Novo Nordisk A/S and Pfizer. His work is supported by more than 70 congress presentations and several peer-reviewed publications. He has also served as an investigator in more than 25 clinical trials in hemostasis, onco-hematology and infectious disease.

Recently, AstraZeneca won approval for the company’s AKT inhibitor Truqap (capivasertib) in combination with Faslodex (fulvestrant) for the treatment of hormone receptor (HR)-positive, HER2-negative locally advanced or metastatic breast cancer with one or more biomarker alterations (PIK3CA, AKT1, or PTEN). The approval of Truqap was the first-in-class approval for AstraZeneca.

Tune into the episode to hear more about the milestone approval of the new combination breast cancer treatment, which has been a much-needed treatment option for the nearly 50 percent of patients with advanced HR-positive breast cancer who have PIK3CA and AKT1 mutations or PTEN alterations, and experience resistance to first-line treatments such as endocrine therapies and CDK 4/6 inhibitors.

For more life science and medical device content, visit the Xtalks Vitals homepage.

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Roosevelt & Shay Greenwood had already endured their share of trials when Roosevelt was diagnosed with stage 4 metastatic prostate cancer in 2016. But God worked a miracle, and not only has Roosevelt lived more than 3 years longer than expected, but his cancer is now "asleep." Listen as he and Shay share how God has made them #GreenwoodStrong.

We all have confessions – thoughts that keep us up at night, that weigh on our shoulders.  Confessions that sometimes when said out loud, we realize aren’t that crazy.  This one is deep, and the start of the Confession Series.  Follow us on Instagram, Facebook and Twitter and respond to our Confession Series posts.  We’ll be sharing confessions, kept anonymous of course.  You can comment, DM, email at badrightbreast@gmail.com or call us in your own voice at 646-494-4962.

Music by Becca Ayers
Additional Music by Baby Goes Bang (Becca Ayers & Russ Rowland)
Graphic Art by Justin West
Website Design by Alec Addalia

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WEBSITE:  www.BadRightBreast.com

In this episode, Ayesha discussed a new blood test developed by researchers at the University of Oxford that can detect cancers and even if they’ve metastasized. The test is based on measuring metabolites produced by tumor cells in blood samples using nuclear magnetic resonance (NMR) spectroscopy. The researchers found that the test could identify cancer among healthy people, those with localized cancer and individuals with cancer that has metastasized. The test could help detect cancers even before the use of conventional imaging-based methods.

The editorial team also discussed Bayer’s commitment to 100 percent green packaging for its consumer products by 2030. The target is part of the company’s sustainability program, which includes shifting to renewable energy sources and sustainably sourcing recyclable and reusable paper materials. Bayer’s most popular consumer products like Aspirin, Aleve and Claritin will all have green packaging by the target year, which will also include recycling information that is consumer friendly. Other pharmaceutical companies like AstraZeneca, GSK and Biogen also have similar sustainability programs, reflecting the growing awareness of the pharmaceutical industry’s large carbon footprint and the importance of efforts to reduce it.

Read the full articles here: 

Cancer Blood Test Developed by University of Oxford Researchers Can Detect Metastasis

Bayer Commits to 100 Percent Green Packaging by 2030

For more life science and medical device content, visit the Xtalks Vitals homepage.

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**Trigger Warning**

Discussion around Radiotherapy treatment experience and how better we can support patients. 

Jo McNamara and Naman Julka-Anderson catch up with Dr. Liz O'Riordan as part of the Living With and Beyond Cancer series (Part 2).

To use this podcast as CPD, look at these reflection points: 

1) Reflect upon your practice within the MDT and how you can utilise the opportunities to ensure that those healthcare professionals consenting patients have an insight into treatments. 

2) Reflect on how you use the patient voice within the department to help develop and enhance the patient experience. 

3) Reflect upon how you can change your practice to ensure patients and HCP’s know your role. 

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Links from podcast:

https://dontignoretheelephant.podbean.com/

https://uk.bookshop.org/books/the-complete-guide-to-breast-cancer-how-to-feel-empowered-and-take-control/9781785041877

Please like and subscribe to Rad Chat on your podcast library.

Our links:

Link Tree: https://linktr.ee/radchat 

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LinkedIn: https://uk.linkedin.com/company/radtalk 

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Twitter: https://twitter.com/rad__chat?lang=en 

When is the right time is to move from a treatment-oriented approach to hospice care? We often hear people struggle with this difficult choice.  Listen to our interview with Chris Sperry as he shares how he and his wife came to the decision to move to hospice care.

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Shanice is a vibrant young woman, who first felt her lump at the age of 23.  After overcoming everything involved with Stage 3 Breast Cancer, she did something that most ‘average’ people don’t have the courage to even attempt.  And then years later out of the blue, she started feeling pain, but no one would listen to her.  So she had to make them.  

Listen to Shanice on her podcast – Love, Her Will:  The New Voice of Willpower with Shanice J.  and follow her on Instagram. 

Music by Becca Ayers
Graphic Art by Justin West
Website Design by Alec Addalia

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WEBSITE:  www.BadRightBreast.com

It’s been one year since the start of Bad Right Breast, and we’re going to take a summer hiatus after next week’s episode.  We’re preparing to return in the fall with three new series:  Motherless Daughters, Artists’ Stories & Meta Stories.  If you feel you have a story to tell in any of these categories, please reach out to us as we’d love to share it.  Next week, will be our first episode in the Meta Stories series.

Music by Becca Ayers
Graphic Art by Justin West
Website Design by Alec Addalia

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WEBSITE:  www.BadRightBreast.com

Rob Paulsen is one of Hollywood’s busiest, most talented, and most passionate performers who specializes in the art of voice acting, a career that has earned him a Daytime Emmy, three Annie Awards, and a Peabody. He is the voice of Pinky from “Pinky and the Brain”, Yakko from “Animaniacs”, Raphael from "Teenage Mutant Ninja Turtles", just to name a few. His accolades and “sunny disposition” stand in stark defiance to the battles he has waged and triumphed over. From a crushing bout of depression at 54 years old to the diagnosis of stage 3 metastatic throat cancer, Rob remains one of the nicest human beings to ever stand in front of a microphone. Rob is now cancer-free and back doing what he loves, with a deep appreciation of what he almost lost and tirelessly using his gifts in service to those that need it the most.

Host: Paul Chamberlain

Guest: Rob Paulsen

Produced by: Cerebral Itch Labs

Engineered & Edited by: April Winchell

Learn more about Smart Funny Tortured: Visit smartfunnytortured.com

Follow Rob Paulsen on Instagram: @rob_paulsen

Follow Rob Paulsen on Twitter: @yakkopinky

Read Rob’s book, Voice Lessons: How a Couple of Ninja Turtles, Pinky, and an Animaniac Saved My Life

Rob would like you to learn more about Boo2Bullying and help eradicate bullying, intolerance and discrimination.

Caryn was a newlywed when she first discovered that she had stage 2 breast cancer.  After treatment, which included a double mastectomy and chemotherapy, she was able to have a baby that she and her husband always wanted.  Then nine years after she completed treatment, she discovered that her cancer had metastasized.  For the past seven years, she is thriving.  She created an entire wellness program, Pretty Wellness.  She wrote a book and has her own podcast, Happiness Through Hardship.  Needless to say, Caryn is living her best life.

You can follow Caryn Sullivan, a two-time cancer survivor, founder of Pretty Wellness, on facebook, instagram and twitter at PrettyWellness or even better, go to her website at PrettyWellness.com.  You can read her book Happiness Through Hardship or subscribe and listen to her podcast with the same name.

Music by Becca Ayers
Graphic Art by Justin West
Website Design by Alec Addalia

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WEBSITE:  www.BadRightBreast.com

For nearly 8 years, I had check-ups, mostly blood work, very few scans. But I admit, throughout those years, I sometimes felt a bit invincible.  One in eight women get cancer, but 30% of that have a reoccurrence.  Finding out my cancer had metastasized to my spine at the height of the pandemic in New York City did not make me feel invincible.  It was however a way for me to have yet again a new perspective on life, as if I needed one.  AND I don’t have to pick up heavy shit anymore.

References:

• Dr. Susan Love's Breast Book, the Fifth Edition

Music by Becca Ayers
Additional Music by Baby Goes Bang (Becca Ayers & Russ Rowland)
Graphic Art by Justin West
Website Design by Alec Addalia

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WEBSITE:  www.BadRightBreast.com

Jennifer is an acupuncturist, mom of two, who had a lumpectomy and then four years later had a reoccurrence and then had a single mastectomy.  But her daughter understands it as ‘it’s not the cancer that can kill you like mine almost did.’  We each have our own stories of cancer, and this is Jennifer’s.

Music by Becca Ayers
Graphic Art by Justin West
Website Design by Alec Addalia

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WEBSITE:  www.BadRightBreast.com

Our 15 volunteers each talk through how they chose their doctors.  Some got second opinions and some didn’t feel the need, while some didn’t have a choice.

You can read Allyson’s article HERE in Medium.

Music by Becca Ayers
Graphic Art by Justin West
Website Design by Alec Addalia

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WEBSITE:  www.BadRightBreast.com

Tissue transfer versus implants.  Lots to consider, time in the hospital, time to recover, invasive vs not so much.  But the idea to choose my size?  That is appealing, but so is a tummy tuck.  Oh, the decisions!  Thankfully Dr. Reconstruction broke down all of the pros and cons.   

BONUS:  At the end of the episode, listen to Baby Goes Bang’s BLUE & COLD, which is featured throughout the podcast.

Music by Becca Ayers
Additional Music by Baby Goes Bang (Becca Ayers & Russ Rowland)
Graphic Art by Justin West
Website Design by Alec Addalia

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WEBSITE:  www.BadRightBreast.com

MRIs and PET scans – why don’t they ever warn you about what it’s really like?  End of the world sirens, horrible shake that you need to drink, and radiation that makes you feel like you’re peeing yourself.  SERIOUSLY!  
References:

• PET Scans:  Healthline 
• MRIs:  WebMD

Music by Becca Ayers
Graphic Art by Justin West
Website Design by Alec Addalia

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WEBSITE:  www.BadRightBreast.com

As I’ve mentioned before, there’s no right way to tell folks you have cancer.  I wanted to be in control of my story, so that if anyone had any questions about what was happening to me, well, they could simply read the truth for themselves.  We all tell our stories in different ways, because they are just that – OUR STORIES.

BONUS:  At the end of the episode, listen to Baby Goes Bang’s THIS SONG (cello by Julia Rogers), which is featured throughout the podcast.

Music by Becca Ayers
Additional Music by Baby Goes Bang (Becca Ayers & Russ Rowland)
Graphic Art by Justin West
Website Design by Alec Addalia

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WEBSITE:  www.BadRightBreast.com

In choosing my doctor, I knew I needed someone that would take the bull by the horns, and take care of the situation, with all the confidence and expertise that was necessary.  I knew I needed someone who would answer my questions, no matter if I thought they were silly or stupid or not.  I knew I needed someone that also was extremely thorough.  And while I always suggest to others to get a second opinion, I never did.  Because I truly felt confident and comfortable with Dr. Breast.

Music by Becca Ayers
Additional Music by Baby Goes Bang (Becca Ayers & Russ Rowland)
Graphic Art by Justin West
Website Design by Alec Addalia

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WEBSITE:  www.BadRightBreast.com

Kim always thought she’d get cancer, but never thought that it would be breast cancer.  Hear how she told her husband, her daughter, her dad and the world, and what type of surgery and treatment took her to the place where she is now.

Music by Becca Ayers
Graphic Art by Justin West
Website Design by Alec Addalia

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WEBSITE:  www.BadRightBreast.com

Fifteen women tell us how they told their spouses, parents, family, loved ones and the world that they had cancer.  We all tell our stories in different ways, for the sheer fact that they are just that – OUR STORIES.  And how people react to them is guaranteed to be very different as well…

Special thanks to Marianne, Kim, Catherine, Katy, Pam, Mary, Sheila, Jennifer, Tiffany, Caryn, Heather, Allyson, Shana, Adina and my Aunt Kathleen for sharing their stories.

Music by Becca Ayers
Graphic Art by Justin West
Website Design by Alec Addalia

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WEBSITE:  www.BadRightBreast.com

Over the course of 2 months during quarantine, I interviewed over a dozen women who had been diagnosed and then treated for breast cancer. All of our stories are unique for the sheer fact that we are each unique.  Not only will you hear many differences in each person’s story, but you’ll also hear some resounding similarities.

Special thanks to Marianne, Kim, Catherine, Katy, Pam, Mary, Sheila, Jennifer, Tiffany, Caryn, Heather, Allyson, Shana, Adina and my Aunt Kathleen for sharing their stories.

Music by Becca Ayers
Graphic Art by Justin West
Website Design by Alec Addalia

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WEBSITE:  www.BadRightBreast.com