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    EP. 104: Fatty Liver 101 | Solo Episode

    enSeptember 06, 2023
    What conditions can lead to fatty liver disease?
    How did Steve Harwell and George Michael's health issues relate to fatty liver?
    Why is strength training important for weight loss?
    What should be considered regarding medications and liver health?
    What resources does Doctor Tina offer for health information?

    • Two famous musicians died from fatty liver caused by obesity and alcoholismObesity and alcoholism can lead to fatty liver, a potentially life-threatening condition. Addressing these risk factors is crucial to prevent complications.

      Obesity and alcoholism can lead to fatty liver, a condition that can have serious consequences, including death. The recent passing of Steve Harwell, lead singer of Smash Mouth, and George Michael, iconic musician, serve as tragic reminders of this. Both struggled with obesity and alcoholism, which likely contributed to their fatty liver diagnoses. Their stories underscore the importance of addressing these risk factors to prevent this condition and its potential complications. It's a critical issue that is often overlooked in the medical community and can impact anyone, regardless of fame or fortune.

    • Metabolic syndrome: A leading cause of fatty liverMetabolic syndrome, also known as MAFLD, is a condition linked to metabolic dysfunction and a major cause of fatty liver. Early recognition and addressing this condition can prevent serious health complications.

      Metabolic syndrome, a condition characterized by metabolic processes going awry inside the body, is a leading cause of fatty liver, which can progress into inflammation, cirrhosis, and liver cancer. This condition, which affects both alcoholics and non-alcoholics, is a major public health concern as it is a common, often silent, condition that can lead to serious health complications. Metabolic associated fatty liver disease (MAFLD) is the new term for this condition, emphasizing its connection to metabolic dysfunction. It's important to note that early signs of fatty liver are often overlooked or normalized, but recognizing and addressing this condition early can prevent or delay the progression to more severe health issues. Additionally, common risk factors for MAFLD include alcohol consumption, certain medications, and a sedentary lifestyle.

    • NAFLD: A Growing Health Concern Affecting 30% of Global PopulationNAFLD, affecting over 30% of the world population, can lead to severe health complications including cardiovascular diseases and increased mortality. Asian and Eastern Indian populations, even those of normal weight with excess midsection fat, are disproportionately affected. Prevention and management are crucial.

      Nonalcoholic fatty liver disease (NAFLD) is a significant health issue affecting over 30% of the global population, and its prevalence is increasing rapidly. This condition, which can lead to more serious forms like Nonalcoholic Steatohepatitis (NASH), cirrhosis, and liver cancer, is often normalized or overlooked. The obesity epidemic and high consumption of processed foods, particularly high fructose corn syrup, are major contributors. Among various demographics, Mexican Americans and Asian populations are disproportionately affected. For Asian and Eastern Indian populations, even seemingly normal weight individuals carrying excess weight in their midsection face higher risks. The progression of this condition can lead to severe health complications, including cardiovascular diseases and increased mortality. It's crucial for individuals, especially those of Asian descent, to be aware of the risks and take steps to prevent and manage NAFLD.

    • Excess midsection weight linked to serious health risksExcess midsection weight can lead to metabolic dysfunction, increasing risk for cardiovascular disease, fatty liver disease, and other health issues. Get tested for fatty liver if you have a large waist circumference, high cholesterol, or high blood pressure.

      Having excess weight in the midsection, even for lean individuals, can lead to serious health risks such as cardiovascular disease and fatty liver disease. Metabolic dysfunction, which affects nearly all Americans, can be a sign of early liver damage. This condition, which ranges from mild to severe, can manifest as high blood pressure, creeping waist circumference, and elevated blood sugar levels. If you suspect you may have metabolic dysfunction, consider getting tested for fatty liver, especially if you have a waist circumference over 35 inches for women or over 40 inches for men, high cholesterol, or high blood pressure. Don't ignore the early signs, as untreated metabolic dysfunction can lead to more severe health issues. For more information, download the "Assess Your Metabolic Health Guide" from Doctor Tina's website.

    • Health markers indicating metabolic dysfunctionStay below specific threshold numbers for waist circumference, triglycerides, and other health markers to prevent metabolic dysfunction and related conditions. Regular check-ups and healthy lifestyle choices are essential.

      Certain health markers, such as high blood pressure, large waist circumference, high triglycerides, and elevated liver enzymes, can indicate metabolic dysfunction and potential risk for conditions like type 2 diabetes and fatty liver disease. These markers serve as red flags, and individuals should aim to stay below specific threshold numbers based on their height. For example, a healthy waist circumference for women is below 35 inches and for men is below 40 inches. High triglycerides, especially when they equal or come close to total cholesterol, can also be a sign of liver issues. It's essential to have regular health check-ups and discuss any concerns with a healthcare professional. Additionally, maintaining a healthy lifestyle, including a balanced diet, regular exercise, and good sleep habits, can help prevent and manage these conditions.

    • Being lean doesn't guarantee good healthLean individuals can have hidden health issues like insulin resistance, fatty liver, and poor muscle growth. Essential aminos aid muscle growth and energy, and a balanced diet is crucial.

      Being lean does not always mean being healthy. The speaker shared examples of individuals, including marathon runners and middle-aged individuals, who appeared lean but had prediabetes labs and fatty liver infiltrate. Factors contributing to this condition included insulin resistance, lack of strength training, and poor diet choices such as consuming refined carbohydrates and artificial sweeteners. The speaker also emphasized the importance of essential amino acids for muscle protein synthesis and highlighted the benefits of using a product like Keyon Aminos for optimal muscle growth and energy. Overall, the discussion underscores the importance of focusing on overall health and wellness, not just appearance.

    • Streamline lab testing process with RUPA HealthFunctional and integrative healthcare professionals can save time and money by using RUPA Health for lab kit shipping and results management. Attract new patients with specialty lab offerings.

      Functional and integrative healthcare professionals can streamline their lab kit process and save time by using RUPA Health. This platform allows for lab kits to be shipped directly to patients' homes or sets up a branded storefront for patients to order tests themselves. The best part is that Rupa handles the money and sends results directly to the practitioner's portal, eliminating the need to log into multiple portals or handle kit shipping. Additionally, offering lab testing through Rupa can attract new patients seeking specialty labs and astute practitioners to interpret the results. The NBC News article highlights the soaring rates of nonalcoholic fatty liver disease, which is largely lifestyle-induced by factors such as obesity, diabetes, and high blood pressure. While genes may play a role, lifestyle choices are the primary drivers of this condition, which can lead to life-threatening conditions like cirrhosis and cancer of the liver. To uplevel your strength game, consider incorporating Kion Aminos into your routine, and for healthcare professionals, RUPA Health can help simplify lab testing processes.

    • Metabolic Associated Fatty Liver Disease: A Growing Health ConcernUp to 25% of the global population had MAFLD in 2013, linked to obesity, diabetes, and aging. Address it through lifestyle changes and professional help to prevent advanced liver damage and potential transplantation. Be cautious with alcohol and Tylenol/acetaminophen.

      Metabolic associated fatty liver disease (MAFLD) is a growing health concern, affecting up to 25% of the global population in 2013, with numbers likely rising. This condition, which can lead to advanced fibrosis or cirrhosis, is closely linked to obesity, type 2 diabetes, and inflammaging in older adults. MAFLD is not limited to alcoholics, as metabolic syndrome plays a significant role in its development. The condition can be addressed through lifestyle changes, including building muscle and working with healthcare professionals such as functional doctors, naturopaths, health coaches, or nutritional therapists. It's essential to take metabolic dysfunction seriously, as it can lead to liver transplantation. Additionally, be cautious when combining alcohol consumption with Tylenol or acetaminophen, as this combination can lead to liver damage.

    • Understanding Medication Risks: Acetaminophen and Liver DamageBe aware of the risks of acetaminophen, especially when combined with alcohol, an unhealthy diet, or metabolic syndrome. Maintain a healthy waist circumference, avoid excessive alcohol consumption, and make informed decisions about medication use to prevent liver damage.

      Many people underestimate the importance of understanding their medication dosages and the potential risks they face when consuming acetaminophen, especially when combined with alcohol or an unhealthy diet. The liver, which is responsible for processing these substances, can suffer significant damage leading to irreversible conditions like cirrhosis. This damage can be exacerbated by metabolic syndrome, which is increasingly common in heavier individuals. Visceral fat, a dangerous type of fat surrounding organs, is a significant contributor to metabolic health issues, including liver disease. High fructose corn syrup and artificial sweeteners are also culprits in this regard. It's crucial to be aware of these risks and take steps to maintain a healthy waist circumference, avoid excessive alcohol consumption, and make informed decisions about medication use. Ignoring these issues can lead to serious health consequences, including the need for a liver transplant.

    • Impact of Artificial Sweeteners and Importance of Strength Training for Metabolic HealthArtificial sweeteners can negatively impact liver function and contribute to metabolic dysfunction. Prioritize strength training for mitigating and modulating metabolic health, essential for maintaining insulin resistance, mitochondrial function, and overall cellular health.

      Maintaining good metabolic health goes beyond just diet and exercise. Artificial sweeteners, even for those who are active and seemingly healthy, can negatively impact liver function and contribute to metabolic dysfunction. Strength training, on the other hand, is essential for mitigating and modulating metabolic health. It sets off a biochemical cascade that is critical for maintaining insulin resistance, mitochondrial function, and overall cellular health. Without strength training, it's difficult to change body composition and reduce inflammation, even if weight is lost. Therefore, it's important to assess metabolic health regularly, educate yourself, and prioritize strength training as part of a holistic approach to maintaining optimal health.

    • Incorporate strength training for optimal weight loss and body compositionStrength training builds muscle mass, offsets insulin resistance, and positively impacts metabolic processes for effective weight loss and improved body composition. Be aware of potential liver stressors like medications, alcohol, and environmental factors to maintain overall health.

      For effective weight loss and improving overall body composition, it's crucial to incorporate strength training into your routine. This not only helps build muscle mass but also offsets insulin resistance and positively impacts various metabolic processes. Neglecting strength training while relying solely on weight loss tools may lead to a smaller version of an unhealthy body composition. Furthermore, it's essential to be aware of potential liver stressors, such as certain medications, alcohol, and environmental factors, as they can contribute to insulin resistance and liver issues. Always consult a healthcare professional for personalized advice regarding your diet, lifestyle, and medication use.

    • Invest in your health with strength trainingStrength train for better health, start with basics, consider hiring a coach, prevent liver inflammation, stay informed, and follow Doctor Tina's podcasts

      Strength training is an essential investment in your health. It's recommended for everyone, regardless of fitness level. Start with basic workouts and consider hiring a coach if you plan to lift heavy weights. Additionally, be aware that COVID can induce liver inflammation, which can worsen health complications. Prevent this by ensuring good health and avoiding chronic inflammation and obesity. Stay informed about your health by getting regular check-ups and assessments from your doctor. Furthermore, consider following Doctor Tina's podcast, "Doctor Tina Show," and her new podcast, "Digest This," for more health and wellness information. Remember, this information is for general informational purposes only and should not replace professional medical advice.

    • Learn about health, nutrition, and wellness with expert interviews and bite-sized knowledge on Digest This podcast.Digest This is a top resource in the nutrition category on Apple Podcasts, featuring expert interviews and bite-sized knowledge on various health and wellness topics, including gut health, food industry, and specific ingredients.

      Bethany's podcast, Digest This, is an informative and easy-to-digest resource for all things related to health, nutrition, and wellness. Each episode features interviews with experts and delves into topics such as gut health, food industry, and specific ingredients. Bethany also provides a weekly segment called "bite of knowledge," where she explores the benefits or dangers of various ingredients commonly used in food, skin care, and household products. With new episodes every Monday and Wednesday, Digest This has quickly become a top resource in the nutrition category on Apple Podcasts. Whether you're interested in learning about the health benefits of olive oil or the potential dangers of certain ingredients in your cereal, Bethany has you covered. Tune in to Digest This on your favorite podcast app for insightful and accessible information on all things health and wellness.

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    In this special episode of The Dr. Tyna Show, I'm tackling the puzzling phenomenon of midlife weight gain—a challenge many of us women face. If you’ve noticed your midsection thickening and overall body changes as you hit middle age, you’re definitely not alone. I’ll break down a recent study on this topic, covering metabolic dysfunction, the role of estrogen, and the impact of physical activity. Join me as I explore the complexities of this stage of life and offer practical solutions, including the benefits of exercise and resistance training. Tune in to uncover the science and get actionable insights for managing your health during this transformative period and learn WHY I think microdosing GLP1 agonists can be such a potent tool in this struggle. On This Episode We Cover: 02:04 - Summarizing the study  07:01 - Metabolic dysfunction in middle aged women  10:03 - The importance of physical activity 11:47 - Disease risk and metabolic syndrome  15:03 - Estrogen, appetite, and physical activity  19:25 - GLP1s, reward pathways, and movement 22:05 - Insulin resistance, mitochondrial and immune dysfunction   25:13 - Testosterone and estrogen rations 26:54 - Adipose tissue dysfunction  28:51 - Obesity, inflammation, and pain  30:11 - Weight affects people differently  33:36 - Therapeutic effects of exercise 35:21 - Insulin resistance 37:43 - The importance of resistance training, HIIT, and yoga  41:52 - Sleep and hormones  44:35 - Study conclusions Sponsored By: BIOptimizers Go to masszymes.com/drtynafree for your first free bottle of Masszymes Maui Nui Use code DRTYNA for 20% off at mauinuivenison.com Show Links: Adipocyte Metabolism and Health after the Menopause: The Role of Exercise Ozempic Done Right University Coupon Code: OUVIP Further Listening EP. 94: For the Men: Master Your Testosterone | Solo Episode EP. 95: Women Need Testosterone, Too | Solo Episode EP. 104: Fatty Liver 101 | Solo Episode EP 106: Ozempic Done Right Part 1 | Solo Episode EP 107: Ozempic Done Right Part 2 | Solo Episode EP. 109: Ozempic Done Right Part 3 | Solo Episode EP. 129: Ozempic Done Right Part 4: Sustained Weight Loss | Solo Episode EP. 132: Ozempic Done Right Part 5: Osteoarthritis + GLP1 Agonists | Solo Episode Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.
    The Dr. Tyna Show
    enJuly 31, 2024

    EP. 162: Optimizing Ozempic, GLP-1 + Metabolic Wellness | Leonard Pastrana

    EP. 162: Optimizing Ozempic, GLP-1 + Metabolic Wellness | Leonard Pastrana
    How do you strike the perfect balance between traditional medication and holistic health approaches? Join me on today’s episode of the Dr. Tyna Show for an enlightening conversation with Dr. Leonard Pastrana, a former pharmacist who transitioned into cellular optimization. We uncover the secrets behind optimizing Ozempic and GLP-1 treatments, focusing on the holistic integration of exercise, nutrition, and comprehensive treatment plans to enhance insulin sensitivity and overall health. Dr. Pastrana sheds light on the biochemical mechanisms of these interventions and their profound impact on mitochondrial function, inflammation reduction, and metabolic health. This episode is jam-packed with practical advice and insights to help you optimize your health journey. Ozempic Uncovered FREE 4 Part Video Series On This Episode We Cover: 01:21 - About Leonard Pastrana 03:21 - Insulin sensitivity and the highlights of exercise 07:20 - Exercise should be at the top of your tool belt 13:14 - The importance of balancing your diet in conjunction with exercise 14:36 - GLP-1 effect on eating disorders 16:43 - Is muscle loss the big crisis? 19:21  - Hydration’s effect on your strength 21:58 - Optimizing hydration 24:24 - Adding electrolytes 26:12  - Longevity Assessments and monitoring the patient 29:11 - Fatty infiltration and self-monitoring 32:25 - Low dose leucine 35:42 - Hormedic pathways and high doses of NAD 39:01 - Citronol LNA 43:35 - Utilizing GLP-1’s for cardiovascular disease 45:07 - The dangers of “skinny fat” 48:07 - Refusing to provide “dosing” over the internet 50:28 - Nucleus Pro for physicians and practitioners Show Links: NuBioAge Link for Practitioners to Register NuBioAge Public Site: Use code DRTYNA to save 10% Withings Scale inside my Amazon Store EP 106: Ozempic Done Right Part 1 | Solo Episode Sponsored By: Qualia - Go to Qualialife.com/DRTYNA for up to 50% off and use code DRTYNA at checkout for an additional 15% off.  Paleo Valley - For 15% off go to http://paleovalley.com/drtyna Divi - Go to diviofficial.com/DRTYNA and use code DRTYNA for 20% off your first order. Timeline Nutrition - Go to timelinenutrition.com/DRTYNA and use code DRTYNA for 10% off Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.
    The Dr. Tyna Show
    enJuly 24, 2024

    EP. 162: Balancing Traditional and Holistic Health: Optimizing Ozempic, GLP-1, and Metabolic Wellness | Leonard Pastrana

    EP. 162: Balancing Traditional and Holistic Health: Optimizing Ozempic, GLP-1, and Metabolic Wellness | Leonard Pastrana
    How do you strike the perfect balance between traditional medication and holistic health approaches? Join me on today’s episode of the Dr. Tyna Show for an enlightening conversation with Dr. Leonard Pastrana, a former pharmacist who transitioned into cellular optimization. We uncover the secrets behind optimizing Ozempic and GLP-1 treatments, focusing on the holistic integration of exercise, nutrition, and comprehensive treatment plans to enhance insulin sensitivity and overall health. Dr. Pastrana sheds light on the biochemical mechanisms of these interventions and their profound impact on mitochondrial function, inflammation reduction, and metabolic health. This episode is jam-packed with practical advice and insights to help you optimize your health journey. On This Episode We Cover: 01:21 - About Leonard Pastra 03:21 - Insulin sensitivity and the highlights of exercise 07:20 - Exercise should be at the top of your toolbelt 13:14 - The importance of balancing your diet in conjunction with exercise 14:36 - GLP-1 effect on eating disorders 16:43 - Is muscle loss the big crisis? 19:21  - Hydration’s effect on your strength 21:58 - Optimizing hydration 24:24 - Adding electrolytes 26:12  - Longevity Assessments and monitoring the patient 29:11 - Fatty infiltration and self-monitoring 32:25 - Low dose leucine 35:42 - Hormedic pathways and high doses of NAD 39:01 - Citronol LNA 43:35 - Utilizing GLP-1’s for cardiovascular disease 45:07 - The dangers of “skinny fat” 48:07 - Refusing to provide “dosing” over the internet 50:28 - Nucleus Pro for physicians and practitioners Show Links: Ozempic Uncovered FREE 4 Part Video Series NuBioAge Link for Practitioners to Register: https://nubioage.com/forms/practice-registration-moore/ NuBioAge Public Site: Use code DRTYNA to save 10% https://shop.nubioage.com?sca_ref=5326068.n9rmUGfOHP Withings Scale inside my Amazon Store: https://www.amazon.com/shop/drtyna Sponsored By: Qualia - Go to Qualialife.com/DRTYNA for up to 50% off and use code DRTYNA at checkout for an additional 15% off Paleo Valley - For 15% off go to http://paleovalley.com/drtyna Divi - Go to diviofficial.com/DRTYNA and use code DRTYNA for 20% off your first order. Timeline Nutrition - Go to timelinenutrition.com/DRTYNA and use code DRTYNA for 10% off Ozempic Uncovered Podcast Series: EP 106: Ozempic Done Right Part 1 | Solo Episode EP 107: Ozempic Done Right Part 2 | Solo Episode EP. 109: Ozempic Done Right Part 3 | Solo Episode Ep. 116: Berberine: NOT Nature's Ozempic | Quick & Dirty EP. 118: My GLP-1 Experience | Quick & Dirty EP. 129: Ozempic Done Right Part 4: Sustained Weight Loss | Solo Episode EP. 132: Ozempic Done Right Part 5: Osteoarthritis + GLP1 Agonists | Solo Episode EP. 136: Ozempic Does NOT Cause Muscle Loss | Solo Episode Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.
    The Dr. Tyna Show
    enJuly 23, 2024

    Related Episodes

    Ep. 10: Dalton Graham: How to Induce Fatty Liver—with Dr. Brian Kerley

    Ep. 10: Dalton Graham: How to Induce Fatty Liver—with Dr. Brian Kerley

    Dr. Kerley and I are joined by Dalton Graham, a student who found himself in a liver pathology lab at Tulane. He had the interesting idea to test if a high-linoleic acid diet could be shown to produce fatty liver disease at the same time it was causing obesity.
    The scientists in the lab required a little convincing that this was a worthy experiment, but one day he arrived to find all the materials he need waiting for him.
    Be careful what you wish for! Find out how it turned out.

    Graham, D. S., Liu, G., Arasteh, A., Yin, X.-M., & Yan, S. (2023). Ability of High Fat Diet to Induce Liver Pathology Correlates with the Level of Linoleic Acid and Vitamin E in the Diet. PLOS ONE, 18(6), e0286726. https://doi.org/10.1371/journal.pone.0286726

    Biography:
    •    Dalton is currently a PhD student at University of Florida, studying Biochemistry with a focus on metabolism. When he wrote the paper we are discussing, he was an undergrad, and then grad student at Tulane University, studying Biochemical Engineering and Pathology.
    _______________________________________
    Co-host Dr. Brian Kerley
    https://www.seedoilrebellion.com/
    https://twitter.com/SeedOilDsrspctr

    Looking to fix your diet by getting rid of seed oils?
    Check out the Seedy app!
    https://www.seedyapp.com/

    Tucker Goodrich
    Substack: https://tuckergoodrich.substack.com/
    Blog (deprecated, but still a lot there!): http://yelling-stop.blogspot.com/
    Youtube: https://www.youtube.com/channel/UCDpWmYeRapRkrZ9zw8M7iFg
    Apple podcast: https://podcasts.apple.com/us/podcast/tucker-goodrich-podcast/id1617481825
    Podcast: https://sites.libsyn.com/408758
    Twitter: https://twitter.com/TuckerGoodrich
    _______________________________________
    Show Notes
    “Alvheim papers out of the NIH”
    Alvheim, A. R., Malde, M. K., Osei‐Hyiaman, D., Hong, Y. H., Pawlosky, R. J., Madsen, L., Kristiansen, K., Frøyland, L., & Hibbeln, J. R. (2012). Dietary Linoleic Acid Elevates Endogenous 2-AG and Anandamide and Induces Obesity. Obesity, 20(10), 1984–1994. https://doi.org/10.1038/oby.2012.38
    Alvheim, A. R. (2012). Dietary linoleic acid induces obesity through excessive endocannabinoid activity [Doctor of Philosophy, The University of Bergen]. https://bora.uib.no/bora-xmlui/handle/1956/5962
    NAFLD discovered in 1980:
    Ludwig, J., Viggiano, T. R., McGill, D. B., & Oh, B. J. (1980). Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clinic Proceedings, 55(7), 434–438.
    Liver transplants and NAFLD:
    Lindenmeyer, C. C., & McCullough, A. J. (2018). The Natural History of Nonalcoholic Fatty Liver Disease—An Evolving View. Clinics in Liver Disease, 22(1), 11. https://doi.org/10.1016/j.cld.2017.08.003
    Linoleic acid and breast milk:
    Goodrich, T. D. (2022, September 1). Podcast Ep. 5: Prof. Tom Brenna on Omega-3 and Omega-6 in Human Health—with Dr Brian Kerley [Blog]. Yelling Stop. http://yelling-stop.blogspot.com/2022/09/podcast-ep-5-prof-tom-brenna-on-omega-3.html
    Gornoski, D. (2021, June 15). Bruce German on How Human Milk Does the Body Good (Jun 15 2021) [Mp3]. https://podcastaddict.com/episode/124448388
    Speakman paper on lethargy:
    Speakman, J. R., De Jong, J. M. A., Sinha, S., Westerterp, K. R., Yamada, Y., Sagayama, H., Ainslie, P. N., Anderson, L. J., Arab, L., Bedu-Addo, K., Blanc, S., Bonomi, A. G., Bovet, P., Brage, S., Buchowski, M. S., Butte, N. F., Camps, S. G. J. A., Cooper, J. A., Cooper, R., … Wong, W. W. (2023). Total Daily Energy Expenditure Has Declined Over the Past Three Decades Due to Declining Basal Expenditure, Not Reduced Activity Expenditure. Nature Metabolism, 5(4), 579–588. https://doi.org/10.1038/s42255-023-00782-2
    Vitamin E:
    Masterjohn, C. (2017, June 24). 032: Is Coconut Oil Killing Us? [Substack newsletter]. Harnessing the Power of Nutrients. https://chrismasterjohnphd.substack.com/p/041-is-coconut-oil-killing-us
    Raghavamenon, A., Garelnabi, M., Babu, S., Aldrich, A., Litvinov, D., & Parthasarathy, S. (2009). α-Tocopherol Is Ineffective in Preventing the Decomposition of Preformed Lipid Peroxides and May Promote the Accumulation of Toxic Aldehydes: A Potential Explanation for the Failure of Antioxidants to Affect Human Atherosclerosis. Antioxidants & Redox Signaling, 11(6), 1237–1248. https://doi.org/10.1089/ars.2008.2248
    NAFLD and Fructose:
    Vos, M. B., Weber, M. B., Welsh, J., Khatoon, F., Jones, D. P., Whitington, P. F., & McClain, C. J. (2009). Fructose and Oxidized LDL in Pediatric Nonalcoholic Fatty Liver Disease: A Pilot Study. Archives of Pediatrics & Adolescent Medicine, 163(7), 674–675. https://doi.org/10.1001/archpediatrics.2009.93
    Cardiolipin:
    Goodrich, T. (2016, February 5). The Cause of Metabolic Syndrome: Excess Omega-6 Fats (Linoleic Acid) in Your Mitochondria. Yelling Stop. http://yelling-stop.blogspot.com/2016/02/the-cause-of-metabolic-syndrome-excess.html

    Quotable: 
    “I made a presentation about the role of excess linoleic acid in liver diseases. …I sat down and I pitched it… to the individuals in that lab. At first they didn’t really get it… I remember when I first finished laying out the mechanisms and why this is needed. Typically at the end of a presentation there are a bunch of questions, and there was just… silence.
    “They’d never been presented with this idea that lipid peroxidation (or oxidative stress) manifests itself mainly due to this dietary factor—that no one seems to realize because it’s so ubiquitous.”
    “These animals that are eating the higher linoleic acid they appear physical slower.”
    “The females that were fed the high linoleic acid, they actually lost a lot of their fur [while under stress]. We couldn’t continue the experiment with them.”
    “I don’t think they understood the importance of [linoleic acid] in the real world.”

    Liver Health Part 2

    Liver Health Part 2

    In this episode Dr. Armitstead continues to explain what you can do for better liver health and to help the body detox.  She shares with you the health benefits of castor oil packs, coffee enemas, oil pulling, and liver flushes.  She also explains the health benefits of olive oil with lemon and different ways to take it to heal. Do you have high cholesterol?  Then listen to this episode where Dr. Armitstead explains the cholesterol myth and why the concept of staying away from high cholesterol foods when trying to lower your cholesterol is actually the opposite of what you need to do.  She also tells you what herbs and foods to add to your diet to help the liver heal.  This episode is great for anyone who wants better liver health,  is tired, has insomnia,  headaches, poor skin health, or feels the need to detox.

    Resources:
    Castor Oil Packs Directions - https://healingartsnyc.blogspot.com/2018/04/health-benefits-of-doing-castor-oil.html

    Liver Flush Directions - https://healingartsnyc.blogspot.com/2015/01/is-your-liver-toxic.html

    Coffee Enema Directions - https://healingartsnyc.blogspot.com/2020/10/the-importance-of-coffee-enemas-for.html

    Banyan Daily Swish - https://healingartsnyc.com/shop/oavjcdijcr9gzahkf8ete9vw69aogx

    Cholesterol Myths Book 



    Why NASH Drug Trials Fail: A Thoughtful, Challenging Theory - Ep 34

    Why NASH Drug Trials Fail: A Thoughtful, Challenging Theory - Ep 34

    Prof. Dr. Jörn M. Schattenberg joins the Surfers to discuss his recent article in Expert Opinion on Investigational Drugs dissecting recent drug trial failures.

    Prof. Dr. Jörn M. Schattenberg joins Stephen, Donna, Louise and Roger to discuss his recent article "The Nonalcoholic Steatohepatitis (NASH) drug development graveyard: established hurdles and planning for future successes." The discussion started with lessons from failed trials, focusing on the importance of utilizing Phase 2 trials to test hypotheses and establish appropriate targets. From there, Surfers went on to discuss commercial and patient-focused definitions of what makes a clinical trial successful.

    Berberine's Metabolic Magic: How it Enhances Your Health Through the Microbiome

    Berberine's Metabolic Magic: How it Enhances Your Health Through the Microbiome
     

    Hey there, welcome back to the Empowered Nutrition Podcast. I'm Erin Skinner, your host, and I'm excited to take you on a journey into the incredible world of Berberine in this episode. Together, we'll discover the superpowers of this natural plant compound and its profound impact on our digestive, metabolic, and hormonal health.

    Berberine: The Unsung Hero Imagine Berberine as the unsung hero of the supplement world. It's not a prescription drug, but it's gaining superstar status for its unique ability to kickstart the release of glucagon-like peptide-1 (GLP-1). These GLP-1 superpowers are a game-changer in the realm of metabolic health.

    Safety First: Navigating the Berberine Universe Let's navigate the safety of Berberine. Most adults can embrace its benefits, but we need to be cautious. Expect some minor side effects like mild abdominal discomfort, constipation, or the occasional bout of nausea. But a word of advice, Berberine is best suited for those facing health challenges. For healthy individuals, it may not be the supplement you're looking for.

    Witness Berberine's Breathtaking Feats Prepare to be wowed by Berberine's breathtaking feats. It swoops in to save the day in the battle against diabetes, polycystic ovary syndrome (PCOS), high cholesterol, and the formidable obesity villain. It's a powerful ally, but having healthcare professionals as your sidekicks when introducing Berberine to your health journey is a smart move.

    Dosing Drama and Cautious Calm Let's dive into the dosing drama. The script reads 500 milligrams, two to three times a day, for one to six months. Berberine may be a powerful ally, but long-term alliances should be approached with caution. Especially if your medication squad is already on standby.

    Berberine's Secret Weapons Discover Berberine's secret weapons as I unravel the six primary mechanisms through which it conquers the battlefield. From rallying nitrate-reducing bacteria to amping up short-chain fatty acid production, this hero doesn't back down. It's all part of the grand plan to reduce inflammation, optimize bile metabolism, foster Akkermansia bacteria growth, and control hormones to slay the dragons of appetite and sugar cravings.

    Calling All Health Warriors Berberine steps into the spotlight when health warriors face particular adversaries. When weight loss resistance, metabolic syndrome, insulin resistance, type 2 diabetes, and PCOS are the battlegrounds, Berberine is your trusty sword. For other quests, consult your healthcare professionals for guidance.

    Enduring Legacy The awe-inspiring aspect of Berberine? Its enduring legacy. Even after Berberine exits the stage, its impact on the gut microbiome continues to shine. It's like having a guardian angel looking out for your health, long after the final bow.

    The Final Act As we wrap up this episode, I hope you've gained a newfound appreciation for the superpowers of Berberine. This superhero in supplement form may be your ticket to a healthier, happier future.

    References used in this podcast episode:

    1.The Natural Medicine’s Database: Berberine (Professional Monograph) https://info.trchealthcare.com/natmed-ppc

    2.Zhang Y, Gu Y, Ren H, et al. Gut microbiome-related effects of berberine and probiotics on type 2 diabetes (the PREMOTE study). Nat Commun. 2020;11(1):5015.

    3.Habtemariam S. Berberine pharmacology and the gut microbiota: A hidden therapeutic link. Pharmacol Res. 2020;155:104722.

    4.Zhang L, Wu X, Yang R, et al. Effects of Berberine on the Gastrointestinal Microbiota. Front Cell Infect Microbiol. 2020;10:588517.

    5.Och A, Och M, Nowak R, Podgorska D, Podgorski R. Berberine, a Herbal Metabolite in the Metabolic Syndrome: The Risk Factors, Course, and Consequences of the Disease. Molecules. 2022;27(4).

    6.Cao RY, Zheng Y, Zhang Y, et al. Berberine on the Prevention and Management of Cardiometabolic Disease: Clinical Applications and Mechanisms of Action. Am J Chin Med. 2021;49(7):1645-1666.

    7.Wang H, Zhang H, Gao Z, Zhang Q, Gu C. The mechanism of berberine alleviating metabolic disorder based on gut microbiome. Front Cell Infect Microbiol. 2022;12:854885.

    8.Li J, Meng P, Zhang J, He M. Effect of Berberine Hydrochloride on the Diversity of Intestinal Flora in Parkinson's Disease Patients. Contrast Media Mol Imaging. 2022;2022:8381870.

    9.Ming J, Yu X, Xu X, et al. Effectiveness and safety of Bifidobacterium and berberine in human hyperglycemia and their regulatory effect on the gut microbiota: a multi-center, double-blind, randomized, parallel-controlled study. Genome Med. 2021;13(1):125.

    Ready to dive in? Listen here!

    Love it? Hate it? We’d love to hear your feedback!  

     

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    Heal your Metabolism with the Lean for Life app: https://empowered-nutrition.ck.page/193bb2cd67

    Help yourself feel aligned using our three phase approach: Lean for Life Membership called Heal, Optimize , and Refinewhere you will be empowered to reverse previous metabolic damage with the assistance of our team of Registered Dietitian Nutritionists. Check out more details on our website!

     

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