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    Why'd I take speed for twenty years? (Part 1)

    enOctober 27, 2023

    Podcast Summary

    • Resisting Medication for ADHDDespite initial resistance, open conversations with healthcare professionals can lead to effective medication management for ADHD.

      Sometimes, people may resist taking medication, even when it could significantly improve their quality of life. In the case of our guest, he initially resisted taking Dexedrine for his ADHD due to his straight edge beliefs and fear of being labeled as a drug user. However, after a persuasive conversation with his doctor, he came to see the medication as a tool, like glasses for his brain, and eventually decided to give it a try. This experience changed his perspective on medication and helped him manage his ADHD symptoms effectively. It's important to remember that everyone's journey with medication is unique, and it's essential to have open and honest conversations with healthcare professionals to make informed decisions.

    • A Man's Unexpected Benefits from Quitting Prescription StimulantsA long-term user of prescription stimulants shares his experience of quitting and the unexpected benefits of increased thoughtfulness and creativity.

      Prescription stimulants, such as Adderall and Ritalin, which are all amphetamines or amphetamine-like drugs, have been a common part of some people's lives for decades, helping them focus and succeed academically and professionally. However, long-term use can lead to dependency and potential negative consequences. One man, who had taken these drugs for 20 years, shared his experience of abruptly stopping their use and the unexpected benefits he gained, including increased thoughtfulness and creativity. He also wondered about the history behind the widespread use of these drugs among his generation, leading him to research and share the story of how prescription stimulants became popular in America.

    • A drug's journey from asthma treatment to stimulantThe history of amphetamines illustrates how a drug's intended use can evolve, from a medical treatment to an illicit substance, reflecting the complex relationship between drugs and society.

      Amphetamines, which started as an asthma medication in the late 1800s, transformed into a widely used prescription drug and later, an illicit substance. The discovery of its central nervous system stimulant effects led researchers to explore its potential uses beyond asthma. Initially tested on humans by its discoverer, Gordon Alles, in 1929, amphetamines were first recognized for their stimulating effects on the mind and body. Despite initial efforts to market it as an asthma medication, its central nervous system effects proved more promising, leading researchers to explore other uses. This "drug looking for a disease" phenomenon is still present in modern drug development, although it's more regulated and systematic today. The history of amphetamines serves as a reminder of the complex and evolving relationship between drugs and society.

    • Marketing Amphetamines in the 1930sIn the 1930s, with minimal regulations, a drug company mailed amphetamines to doctors for testing, leading to widespread use and misuse in psychiatric institutions.

      In the 1930s, a powerful new drug named amphetamine was discovered, and its creator, Gordon Allies, looked for a disease to apply it to. He found a small market in narcolepsy, but wanted a larger market. He partnered with Smith, Klein, and French, an American pharmaceutical company, to market and test the drug on a larger scale. At the time, there were minimal regulations on medicines, and Smith, Klein, and French mailed large amounts of the drug to doctors for them to test and report back. Many of these trials took place in psychiatric institutions, where mental patients had little say in their treatment. The drug was tested for various conditions, including schizophrenia and alcoholism, but didn't prove effective for those indications. Abraham Meyerson, a psychiatry professor from Tufts and Harvard Medical Schools, became a big champion of the drug and even used it himself. The pharmaceutical environment was much laxer than today, and it wasn't until a scandal involving a strep throat medicine that regulations on proving safety and efficacy before selling a drug were put in place.

    • The marketing of amphetamine as the world's first antidepressantAbraham Meyerson's theory of depression as a lack of motivation led to amphetamine's marketing as a treatment for depression, shifting the definition of depression from chronic weakness to a lack of productivity and zest.

      The discovery and marketing of amphetamine as the world's first antidepressant in the 1930s significantly shaped our cultural understanding of depression. Abraham Meyerson, a psychiatrist who was experimenting with amphetamine for its mood-enhancing effects, had a new theory of depression as a lack of motivation or drive. This definition aligned with the needs of the American company, Smith, Klein, and French, which was marketing amphetamine as a treatment for depression. As a result, the idea of depression shifted from being seen as chronic weakness or fatigue to a lack of productivity and zest. This marketing campaign was successful, and depression came to be defined by this new criteria in the 1940s, influencing the development of subsequent antidepressants. The way we recognize and understand depression continues to be shaped by cultural and societal factors, making it a complex and evolving concept.

    • Redefining Depression: Amphetamines from Decongestant to AntidepressantInitially considered a nasal decongestant, amphetamines were later redefined as an antidepressant, leading to a significant market opportunity during WW2 due to their potential benefits for soldiers experiencing combat fatigue.

      The experience of illness, whether physical or mental, goes through a filtration process by the medical profession, who diagnose and group symptoms together based on their theories. This process can lead to different interpretations and treatments. For instance, amphetamine, initially an unpopular nasal decongestant, became the world's first antidepressant by redefining depression and treating a lack of energy and motivation. During World War 2, this expanded understanding of depression led doctors to prescribe amphetamines to soldiers experiencing combat fatigue, marking a significant market opportunity for pharmaceutical companies. Despite initial resistance from the military, amphetamines were issued widely due to their potential benefits for soldiers. This example highlights the complex relationship between medical diagnoses, treatments, and societal perceptions.

    • Methamphetamine use in World War 2 for staying awake and boosting moraleDuring WW2, soldiers preferred methamphetamine over caffeine for staying awake and boosting morale, despite similar effects, illustrating the drug's marketing appeal

      During World War 2, both the Allied and Axis powers widely used methamphetamine, primarily in pill form and at doses similar to those used for attention deficit treatment today. The drugs were issued for various reasons, including staying awake in dangerous situations and boosting morale. Interestingly, studies conducted by the Allies showed that there was little difference between the effects of methamphetamine and caffeine, but soldiers preferred the former due to its morale-boosting effects. This use of methamphetamine as a mind-altering drug, with fatigue being the official rationale, can be seen as a form of marketing to both the military brass and the soldiers themselves. Despite its reputation as a strong and serious drug, the doses and methods of use during this time were not drastically different from those used for medical purposes today.

    • Soldiers with mental health issues during WW2 were kept near the front line for recoveryWW2 soldiers with mental health issues were given rest and talk therapy while near the front line, illustrating societal expectations and the definition of health and illness, but post-war, amphetamines led to the first epidemic due to societal shifts and new treatments

      During World War II, soldiers with mental health issues were given the belief that they would get better with rest and talking therapy, while being kept close to the front line. This approach aimed to help them recover and return to their units, illustrating the relationship between societal expectations and the definition of health and illness. Post-war, amphetamines became widely used for various purposes, including weight loss, leading to the first amphetamine epidemic in America. However, societal attitudes shifted, and the drug's reputation suffered due to a combination of factors, including the emergence of new antidepressants, cultural changes, and moral panics around drug use. This shift led to the decline of prescription stimulants' popularity.

    • The Controlled Substances Act of 1970 and the Decline of AmphetaminesThe Controlled Substances Act of 1970 led to a significant decrease in the legitimate pharmaceutical market for amphetamines, paving the way for the rise of other drugs and increasing scrutiny of their use, particularly in children. Squarespace helps entrepreneurs build a website, engage audience, and sell products/services easily.

      The Controlled Substances Act of 1970 marked a turning point in the regulation and perception of prescription stimulants, particularly amphetamines, in the United States. Prior to this act, amphetamines were widely used for various purposes, including dieting and treating depression, but their recreational use was becoming increasingly problematic. In response, the US government declared war on drug abuse and passed the Controlled Substances Act, which classified amphetamines as a Schedule 2 drug, requiring a prescription and strict monitoring. This led to a significant decrease in the legitimate pharmaceutical market for amphetamines and paved the way for the rise of other drugs, such as cocaine, in the 1970s. The act also highlighted the addictive potential of prescription stimulants and led to increased scrutiny of their use, particularly in children. Despite the challenges in creating a website, Squarespace offers an all-in-one platform for entrepreneurs to build a beautiful website, engage with their audience, and sell products or services with ease.

    • Create personalized websites with Squarespace and NerdWallet's financial toolsSquarespace offers a custom website design system and NerdWallet helps compare credit cards for optimal rewards

      Squarespace offers a personalized website design system with flexible payments and seamless checkout options. For creators looking to unlock their unbreakable creativity, Squarespace's Fluid Engine is the next generation website editor. Meanwhile, NerdWallet can help you compare top travel credit cards to maximize your rewards, potentially leading to free flights or upgrades. In the past, amphetamine was used for various purposes, but after becoming a schedule 2 drug, its uses were limited to narcolepsy and hyperkinetic disorder of childhood. The effectiveness of these drugs for cognitive enhancement is still a topic of debate, with some arguing they are confidence pills or turbo placebos. Squarespace: Start your personalized website today with a free trial at squarespace.com and save 10% off your first purchase at squarespace.com/engine. NerdWallet: Compare credit cards, savings accounts, and more to finance smarter at nerdwallet.com.

    • The use of focus-enhancing drugs like Ritalin and Adderall has surged in the US since the 1960s, particularly for treating ADHD.14 million Americans use focus-enhancing drugs for ADHD, driven by societal changes, pharmaceutical marketing, and the transformation of hyperkinetic disorder to ADHD

      The use of focus-enhancing drugs, such as Ritalin and Adderall, has significantly increased in the United States since the 1960s, particularly for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). Initially used to help children with hyperactivity, these drugs were not widely prescribed due to their classification as schedule 2 drugs under the 1970 Drug Control Act. However, as the condition became more widely recognized and accepted, prescriptions for children and adults began to climb, with an estimated 14 million Americans receiving prescriptions last year. The rise in use can be attributed to a combination of factors, including societal changes and pharmaceutical marketing. The drugs are believed to help individuals concentrate and elevate mood, although these benefits were recognized as early as the 1930s. The transformation of the condition from hyperkinetic disorder to ADHD in the 1970s also played a role in the increase in prescriptions. The disparity between the number of cases in the US compared to other countries suggests that cultural and societal factors may be contributing to the high rate of diagnosis and treatment.

    • Personal journey of being diagnosed with ADHDDiagnosis of ADHD can provide valuable insights and accommodations, but accuracy and societal expectations can impact perception

      The diagnosis of Attention Deficit Hyperactivity Disorder (ADHD) can significantly impact an individual's life, providing explanations, accommodations, and a sense of understanding. However, the accuracy of the diagnosis can be subjective, and the perception of having ADHD can vary greatly depending on societal expectations and the specific demands of one's environment. The speaker in this text shares their personal journey of being diagnosed with ADHD and the impact it had on their life, including the accommodations they received and the self-understanding it provided. However, they later discovered they did not fully meet the diagnostic criteria and had been misdiagnosed. Despite this, the speaker values the experience and the insights it gave them, even if the label was not entirely accurate. Ultimately, the speaker reflects on the importance of understanding one's brain and the complex relationship between diagnosis, societal expectations, and personal identity.

    • The Power of Family Support During Challenging TimesResilience and family support are crucial during tough experiences. Host PJ Vogt shares his personal story of having a brain tumor as a child and the reassuring words from his father that helped him get through it. The episode emphasizes the importance of positivity and leaning on loved ones during difficult times.

      Key takeaway from this episode of Search Engine is the importance of resilience and the role of family support during challenging times. Host PJ Vogt shares his personal story of having a brain tumor at the age of 8 and the reassuring words of his father that helped him get through the experience. Despite the seriousness of the situation, PJ maintains a lighthearted and engaging tone throughout the episode. He also acknowledges the team behind the show and thanks the listeners for their support. Overall, the episode highlights the power of positivity and the importance of leaning on loved ones during difficult times. If you're looking for a reminder to stay strong and keep pushing forward, give Search Engine a listen. And don't forget to rate and review the show on Apple Podcasts to help spread the word!

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